scholarly journals Low Bone Mass and Osteoporosis in Women Referring themselves to Dual X-Ray Absorptiometry - Experience with a Health Promotion Action

2010 ◽  
Vol 3 (1) ◽  
pp. 29-33
Author(s):  
Gerhard W. Goerres ◽  
Jaap Swanenburg ◽  
Daniel Uebelhart
Keyword(s):  
Health Promotion ◽  
Bone Mass ◽  
The Self ◽  
Low Bone Mass ◽  
X Ray ◽  
Female Patients ◽  
Bmd Testing ◽  
Significant Difference ◽  
The Difference ◽  
Prevalence Of Osteoporosis

Aims: This retrospective analysis was done to describe the difference in the prevalence of osteoporosis/low bone mass between women referring themselves to bone mineral density (BMD) testing with dual X-ray absorptiometry (DXA) and women referred by their family practitioner. Methods: Women were recruited by a health promotion action in a Swiss weekly periodical and compared with female patients sent by their physician for DXA testing for various medical indications during the same period. Patients under steroid treatment, known previous fracture and undergoing follow-up for low bone mass were excluded. Self referred women were compared to female patients aged 40 years and older and the same evaluation was repeated for women aged 65 and older. Results: No differences were found in the prevalence of osteoporosis /low bone mass in women referred by their physician vs those who were self referred. However, a significant difference was found with age: the self referred women were 63.1 ± 8.6 years of age whereas the patient group’s mean age was 59.7 ± 9.4 (p=0.0001, 95% CI of the difference: 21 – 61 years). Conclusion: We suggest that health promotion actions might be able to recruit the correct candidates for BMD testing, since we found no significant difference in the prevalence of osteoporosis/ low bone mass between self referred and physician referred women. Our data further suggest that physicians may react earlier on their patient’s risk profiles than the time frame of action by the self-referred women.

scholarly journals SAT0450 GLUCOCORTICOID-INDUCED OSTEOPOROSIS IN PATIENTS WITH CHRONIC INFLAMMATORY RHEUMATIC DISEASES: A MULTIVARIATE LINEAR REGRESSION ANALYSIS IDENTIFYING PREDICTIVE FACTORS FOR LOW BONE MASS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1182.2-1182
Author(s):  
E. Wiebe ◽  
D. Freier ◽  
D. Huscher ◽  
R. Biesen ◽  
S. Hermann ◽  
...  
Keyword(s):  
Bone Mass ◽  
Rheumatic Diseases ◽  
Positive Association ◽  
Fragility Fractures ◽  
Life Time ◽  
Inflammatory Rheumatic Diseases ◽  
Low Bone Mass ◽  
Cross Sectional ◽  
Chronic Inflammatory Rheumatic Diseases ◽  
Prevalence Of Osteoporosis

Background:Rheumatic diseases are associated with increased systemic bone loss and fracture risk related to chronic inflammation, disease-specific, general and demographic risk factors as well as treatment with glucocorticoids (GC). Yet, there is evidence that GCs may, by adequately suppressing systemic inflammation, also have a positive effect on bone mineral density (BMD) and fracture risk1.Objectives:The purpose of this study was to investigate the prevalence of osteoporosis and fragility fractures in patients with inflammatory rheumatic diseases and to analyze the impact that treatment with GCs, other known risk factors and preventive measures have on bone health in these patients.Methods:Rh-GIOP is an ongoing prospective observational study collecting and analyzing disease- and bone-related data from patients with chronic inflammatory rheumatic diseases and psoriasis treated with GCs. In this cross-sectional analysis, we evaluated the initial visit of 1091 patients. A multivariate linear regression model with known or potentially influential factors adjusted for age and sex was used to identify predictors of BMD as measured by dual-energy X-ray absorptiometry (DXA). Multiple imputation was applied for missing baseline covariate data.Results:In the total cohort of 1091 patients (75% female of which 87.5% were postmenopausal) with a mean age of 62.1 (±13.2) years, the prevalence of osteoporosis by DXA was 21.7%, while fragility fractures have occurred in 31.2% of the study population (6.7% vertebral, 27.7% non-vertebral). Current GC therapy was common (64.9%), with a median daily dose of 5.0mg [0.0;7.5], a mean life-time total GC dose of 17.7g (±24.6), and a mean GC therapy duration of 7.8 years (±8.5). Bisphosphonates were the most commonly used anti-osteoporotic drug (12.6%).Multivariate analysis showed that BMD as expressed by the minimum T-Score at all measured sites was negatively associated with higher age, female sex and menopause as well as Denosumab and Bisphosphonate treatment. A positive association with BMD was found for body mass index as well as current and life-time (cumulative) GC dose. While comedication with proton-pump-inhibitors significantly predicted low bone mass, concomitant use of non-steroidal anti-inflammatory drugs showed a positive association with BMD. Of the measured bone-specific laboratory parameters, higher alkaline phosphatase levels were determinants of low DXA-values, while the association was positive for gamma-glutamyltransferase.BMD was neither predicted by duration of GC treatment nor by treatment with disease modifying anti-rheumatic drugs.Predictive variables for BMD differed at the respective anatomical site. While treatment with Denosumab predicted low bone mass at the lumbar spine and not at the femoral neck, the opposite was true for health assessment questionnaire (HAQ) score. Current and life-time GC-dose as well as direct sun-exposure of more than 30 minutes daily were positively associated with bone mass at the femoral sites only.Conclusion:This cross-sectional analysis of a prospective cohort study quantified the prevalence of osteoporosis and identified predictive variables of BMD in patients with rheumatic diseases.Multivariate analyses corroborated low BMD to be predicted by traditional factors like age, female sex and menopause but showed current and well as life-time GC dose to be positively associated with BMD in our cohort of patients with chronic inflammatory rheumatic diseases. This suggests that optimal management of disease activity with GCs might be beneficial in order to avoid bone loss due to inflammation.References:[1]Güler-Yüksel et al. “Glucocorticoids, Inflammation and Bone.” Calcified Tissue International (January 08 2018).Disclosure of Interests:Edgar Wiebe: None declared, Desiree Freier: None declared, Dörte Huscher: None declared, Robert Biesen: None declared, Sandra Hermann: None declared, Frank Buttgereit Grant/research support from: Amgen, BMS, Celgene, Generic Assays, GSK, Hexal, Horizon, Lilly, medac, Mundipharma, Novartis, Pfizer, Roche, and Sanofi.

scholarly journals Femoral Neck Width Predict Low Bone Mass in Patients with Multiple Hereditary Exostoses

2021 ◽  
Author(s):  
Kazu Matsumoto ◽  
Hiroyasu Ogawa ◽  
Satoshi Nozawa ◽  
Haruhiko Akiyama
Keyword(s):  
Femoral Neck ◽  
Bone Mass ◽  
Z Score ◽  
Low Bone Mass ◽  
Mineral Density ◽  
Multiple Hereditary Exostoses ◽  
Neck Width ◽  
T Score ◽  
Significant Difference ◽  
Femoral Neck Width

Abstract Background: Recent report revealed multiple hereditary exostoses (MHE) patients showed the osteoporosis. This study aimed to determine if proximal femur deformities can indicate low bone mass in MHE patients and to investigate the correlation between Z-score or T-score and hip geometry parameters. Patients and Methods: Twenty MHE patients from unrelated families were included in this study. Bone mineral density (BMD) of both femoral neck (n = 40) was examined using dual-energy x-ray absorptiometry. We examined femoral neck axis length (FNAL), femoral head diameter (FHD), femoral neck width (FNW), femoral shaft width (FSW), and femoral neck angle (FNA) and calculated the femoral head-neck ratio (FHNR=FHD/FNW). We examined the correlation between these parameters and Z-score or T-score using linear regression analysis followed by Spearman rank correlation coefficient.Results: Of the patients, 91.7% (22 of 24) male and 100% (16 of 16) female had a Z-score <0 in the femoral neck area. Results also showed that the femoral neck area of 62.5% (15 of 24) male and 56.3% (9 of 16) female patients are within the range for osteopenia. The femoral neck are of seven patients (17.5%) were found to be within the range for osteoporosis. These results suggest that MHE patients tend to have low bone mass. We found a significant correlation between FNW and Z-score (r = -0.3924, P = 0.0123), but there was no significant difference between Z-score and FNAL, FHD, FSW, NSA, and FHNR. We also found that there were significant differences between T-score and FNW and T-score and FHNR (r = -0.4787, P = 0.0018 and r = 0.3636, P = 0.0211, respectively). There was no significant difference between T-score and the other parameters.Conclusions: We found that the femoral neck width significantly correlates with Z-score or T-score. These results suggest that the femoral neck width may be a reliable predicting factor of bone mineral density.

scholarly journals THE ERGONOMIC ELDERLY GYM IMPROVING PHYSICAL FITNESS AND INCREASING THE BONE MASS OF THE ELDERLY

2020 ◽  
Vol 1 (2) ◽  
pp. 1
Author(s):  
N.N. Ariati ◽  
N. Adiputra ◽  
K. Tirtayasa ◽  
I.P.G. Adiatmika ◽  
A. Pangkahila ◽  
...  
Keyword(s):  
Bone Mass ◽  
Physical Fitness ◽  
The Elderly ◽  
T Test ◽  
Wilcoxon Test ◽  
Whole Body ◽  
Distribution Data ◽  
Paired Sample ◽  
Significant Difference ◽  
The Difference

The public is increasingly aware of the importance of exercise for the elderly because exercise is an option to reduce complaints due to setbacks and improve the health of the elderly. In fact the implementation in the field is often wrong as in Banjar Benaya which implements routine exercises only once a week with a duration less than 30 minutes, does not pay attention to nutritional needs, does not use sports clothing, and displays that are not clear. The measurement of elderly physical fitness is still relatively low. Based on these problems, improvements were made to the application of ergonomic elderly gymnastics due to improve elderly’s physical fitness and increase the bone mass.  This study used a treatment by subject design conducted in April 2017-August 2018. The target population was all elderly in Denpasar and the affordable population was determined by multistage random sampling then selected Banjaya Benaya Peguyangan Village with a sample of 20 people who met the inclusion criteria. The data collection were physical fitness and bone mass. The difference in treatment effects were analyzed using a Paired Sample t-Test with α = 0.05 for data with normal distribution and Wilcoxon test, α = 0.05 for data with abnormal distribution. Data showed that there were differences in physical fitness improvement in Period I and Period II after 8 weeks of gymnastics at 43.43% with very bad categories being bad, the difference in increase in whole body bone mass was 16.76% and leg bone mass 68.67%. Analysis of Paired Sample-t-Test physical fitness data and Wilcoxon test for bone mass data in Period I and Period II after gymnastics for 8 weeks, found that there was a significant difference (p <0.05). It can be concluded that ergonomic elderly gym can significantly improve physical fitness and increase bone mass of the elderly. It is recommended that the elderly continue to exercise with a duration of 30-45 minutes, the frequency of 3 times a week to maintain elderly’s physical fitness.

scholarly journals Occupational structure of bearers of Jewish rabbinical, occupational and generic surnames

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 971
Author(s):  
Alexander Jonathan Vidgop ◽  
Nelly Norton ◽  
Nechama Rosenberg ◽  
Malka Haguel-Spitzberg ◽  
Itzhak Fouxon
Keyword(s):  
Confidence Interval ◽  
The Self ◽  
The Other ◽  
Occupational Structure ◽  
Significant Difference ◽  
Standard Classification ◽  
The Difference ◽  
The Individual ◽  
Study Choice

We study choice of profession in three groups of Russian-speaking Jewish families with different occupational distributions of the ancestors. This study continues exploration of the persistence of social status of families over centuries that was initiated in recent years. It was found previously that in some cases professions remain associated with the same surnames for many generations. Here the studied groups are defined by a class of the surname of individuals composing them. The class serves as a label that indicates a professional bias of the ancestors of the individual. One group are the bearers of the class of surnames which were used by rabbinical dynasties. The other group is constituted by occupational surnames, mostly connected to crafts. Finally, the last group are generic Jewish names defined as surnames belonging to neither of the above groups. We use the self-collected database that consists of 858 and 1057 of the first two groups, respectively, and 7471 generic Jewish surnames. The statistics of the database are those of individuals drawn at random from the considered groups. We determine shares of members of the groups working in a given type of occupations together with the confidence interval. The occupational type’s definition agrees with International Standard Classification of Occupations. It is demonstrated that there is a statistically significant difference in the occupational structure of the three groups that holds beyond the uncertainty allowed by 95% confidence interval. We quantify the difference with a numerical measure of the overlap of professional preferences of different groups. We conclude that in our study the occupational bias of different population groups is preserved at least for two centuries that passed since the considered surnames appeared.

scholarly journals Semi-automated approach in the evaluation of low bone mass using clavicle radiogrammetry technique

2018 ◽  
Vol 7 (2.8) ◽  
pp. 169
Author(s):  
U Snekhalatha ◽  
D Ashok Kumar ◽  
Padma Javasan
Keyword(s):  
Bone Mineral Density ◽  
Bone Mass ◽  
Bone Mineral ◽  
Cortical Thickness ◽  
Total Population ◽  
Low Bone Mass ◽  
Mineral Density ◽  
X Ray ◽  
Post Menopausal ◽  
The Right

Background: Low bone mineral density increasing with age is a universally observed phenomenon. This leads to osteoporosis, which is a regressive change that occurs in the bone and it is diagnosed before the occurrence of fractures. The dual energy x -ray absorptiometry (DXA) is considered to be the standard measurement for the detection of bone mineral density (BMD).Objectives: To measure the various bone mass indices in the clavicle bone by radiogrammetric method from a posterior-to-anterior (PA) view of chest digital X-ray using semi- automated method.Methods: Forty women whose mean age was found to be 46.05±15.53 years were included in this study. For the total population (n=40), the right femur BMD was acquired by DXA scanner. The digital chest radiographs were taken for all the subjects. In all cases, the geometrical variables such as periosteal width (CLR-D), endosteal width (CLR-d), cortical thickness (CLR-CT) and percentage cortical thickness %(CLR-CT) were measured in the right clavicle bone region by semi-automated method approach developed in MATLAB software.Results: The CLR-CT (r=0.77) as well as with % CLR-CT (r=0.72) has provided statistically significant correlation (p < 0.01) with the total hip BMD in the total population studied. The pre-menopausal and post-menopausal of the studied population demonstrated a high significance value of (p < 0.01).Conclusion: The semi-automated measurement of low bone mass indices in clavicle radiogrammetry will be useful in the evaluation of low bone mass in post-menopausal women and elderly aged population. This method can be used as a screening tool for mass population, especially in rural India.

scholarly journals Size Does Not Make the Difference: 3D/4D Transperineal Sonographic Measurements of the Female Urethra in the Assessment of Urinary Incontinence Subtypes

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Tomas Kupec ◽  
Ulrich Pecks ◽  
Charlotte M. Gräf ◽  
Elmar Stickeler ◽  
Ivo Meinhold-Heerlein ◽  
...  
Keyword(s):  
Urinary Incontinence ◽  
Stress Urinary Incontinence ◽  
Study Groups ◽  
Transperineal Ultrasound ◽  
Urgency Urinary Incontinence ◽  
Control Group ◽  
Female Urethra ◽  
Female Patients ◽  
Significant Difference ◽  
The Difference

Purpose.The objective was to evaluate the usefulness of transperineal ultrasound in the assessment of the urethral length and urethral lumen by 3D/4D transperineal sonography to discriminate between female patients with subtypes of urinary incontinence.Methods.A total of 150 female patients underwent an examination because of urinary incontinence. 41 patients were diagnosed with urgency urinary incontinence (OAB), 67 patients were diagnosed with stress urinary incontinence (SUI), and 42 patients were in the control group (CTRL). Three diameters of the urethral lumen (proximal (U1), medial (U2), and distal (U3)) and the urethral length were measured. By the assessment of the urethral lumen, the presence of the urethral funneling was evaluated.Results.We found a significant difference in the urethral length and urethral lumen U2 of OAB and SUI versus CTRL. The urethral length was significantly greater (P<0.05) and the urethral lumen was significantly wider (P<0.05) in the patients with urinary incontinence. The incidence of the urethral funneling was significantly higher (P<0.05) in the study groups with urinary incontinence than in the control group.Conclusions.Our results have shown the urethral changes obtained by ultrasound in patients with urinary incontinence, but they are still insufficient to distinguish between subtypes of urinary incontinence.

scholarly journals Objective Quantification of Trochlea Dysplasia: Assessment of Morphology Difference Between Control and Chronic Patellofemoral Instability Patients

2017 ◽  
Vol 5 (4_suppl4) ◽  
pp. 2325967117S0013
Author(s):  
Andreas Voss ◽  
Andrea Achtnich ◽  
Shin Sanghin ◽  
Akin M. Murakami ◽  
Cory Edgar
Keyword(s):  
Trochlear Dysplasia ◽  
Patellofemoral Instability ◽  
Volumetric Analysis ◽  
Patella Instability ◽  
Control Cohort ◽  
X Ray ◽  
Significant Difference ◽  
Trochlea Dysplasia ◽  
The Difference ◽  
Gender Based

Aims and Objectives: Trochlear dysplasia is an important risk factor associated with patellofemoral instability, but it remains difficult to classify with consistency. Currently there is no objective way to quantify the dysplasia. The purpose of this study to define and quantify objectively the trochlea morphology by volume and length via computed tomography (CT). Hypothesis: A significant difference in trochlea groove volume and length is present within a cohort of patients with recurrent patellofemoral instability if compared to a control cohort of similar patients. Materials and Methods: One-hundred control patients (136 knees) were retrospectively reviewed and compared to 36 consecutive patients (72 knees) who were treated surgically for recurrent patella instability and known trochlea dysplasia based on a lateral x-ray. Trochlea morphology was analyzed from a pre-operative CT and data presented as trochlear sulcus volume trochlea length. To determine where along the trochlea length dysplasia is most variable, the trochlea length was radiographically divided into thirds, volume was quantified along that section and compared to control trochlea. Results: A significant difference in trochlea morphology exists between cohorts, volume (1.98 vs 3.77 cm3) and length (31.97 vs 34.66 mm). However, there appears to be a gender based difference in trochlea morphology. The trochlea volumetric analysis between the female cohorts (L: 2.02 cm3 vs. 2.94 cm3, R: 1.95 cm3 vs. 2.93 cm3) demonstrated significant less volume in instability patients (p<0.001). The proximal 30% of trochlea contributed the majority of dysplasia difference determined by comparing mean trochlea volume, 95% of the difference. This difference decreased in distal sections, 53% and 32% respectively. The total trochlea length did not appear to be significant (L: p=0.858, R: p=0.913). It appears dysplasia alone may not directly lead to symptoms demonstrated by trochlea volumetric comparisons within symptomatic recurrent patella instability and contralateral asymptomatic patella (p=0.274). Conclusion: The authors believe this reproducible technique can be used to quantify the trochlea morphology into measurements to be used describing the severity of the dysplasia. The data confirms that symptomatic trochlea dysplasia is a “proximal” process affecting early knee flexion contact between patella and trochlea.

scholarly journals An Investigation Into Learners’ Autonomy At An Institution In Vietnam

2021 ◽  
Vol 04 (10) ◽  
Author(s):  
Pham Thu Trang ◽  
Keyword(s):  
Learning Styles ◽  
Learning Style ◽  
Mixed Method ◽  
Female Students ◽  
The Self ◽  
Mixed Method Research ◽  
Significant Difference ◽  
Medium Level ◽  
The Difference ◽  
The Relationship

The study employed a mixed method research design to investigate the self-perceived levels of learners’ autonomy at the institution where the researcher works. The study also explores the teachers’ support in fostering students’ autonomy. In addition, the study attempts to determine the relationship between genders, learning styles and the learners’ levels of autonomy. The main findings reveal that the level of learners’ autonomy where the study was conducted was at medium level (M = 2.66 out of 5.0 scale). In terms of the students’ perception of their teachers’ roles in fostering students’ autonomy, the finding of the current study reveals that it was quite supportive (M = 3.29 out of 5.0 scale). The finding also indicated that the difference in level of autonomy is not significant between male and female students (M = 2.667 for male compared with M = 2.668 for female students). Finally, the result showed that there a statistically significant difference in the levels of autonomy between students with different learning styles. To be specifically, the students who prefer kinesthetic learning style possess the highest level of autonomy (M = 2.75) compared with M = 2.60 and 2.59 for visual and individual learning style students. M=2.72; M=269 and M=2.62 are the level of autonomy for group, tactile and auditory students respectively.

scholarly journals The Difference of Educational Effectiveness Using Presentation Slide Method with Video About Prevention of Hypertension on Increasing Knowledge and Attitude in People with the Hypertension Risk in Amplas Health Center

2019 ◽  
Vol 7 (20) ◽  
pp. 3478-3482 ◽  
Author(s):  
Arlinda Sari Wahyuni ◽  
Rina Amelia ◽  
Immanuel F. F. Nababan ◽  
Dary Pallysater ◽  
Nadhilah Khairina Lubis
Keyword(s):  
Health Promotion ◽  
Slide Presentation ◽  
Significant Difference ◽  
Quasi Experimental ◽  
Patients At Risk ◽  
Increasing Knowledge ◽  
The Difference ◽  
Knowledge And Attitude ◽  
Prevention Of Hypertension ◽  
Comparison Of Effectiveness

BACKGROUND: The prevalence of prehypertension in the world reaches 20-25% with a figure that is still high in Indonesia (48.4%). The role of health promotion is substantial in an effort of prevention and treatment of hypertension. AIM: This study aims to determine the difference of effect between health promotion using media slides presentation and with video in increasing knowledge and attitude regarding the prevention of hypertension in patients at risk hypertension at Puskesmas Amplas. METHODS: his study uses a Quasi-Experimental design which from 48 samples that meet the criteria inclusion will be immediately given health promotion interventions with slides presentation and video. Respondents will be asked to fill out a questionnaire about knowledge and attitudes before and after the intervention. Data processing is done using the SPSS version 20 application. RESULTS: Distribution level of the knowledge of respondents before the intervention (Pretest) and after the intervention (Posttest) is (9.8, 2.68 vs 13.2, 1.58). Distribution of the pretest vs respondent's attitude level. Post test is (29.7, 2.76 vs 33.2, 3.52). Based on the comparison of effectiveness between video and slide presentation, the significance value of knowledge was 0.072, and the significance value of attitude was 0.000. CONCLUSION: There was a significant difference in effectiveness between video with a slide presentation on improving attitudes towards hypertension prevention, and there were no significant differences in effectiveness between videos with slides presentation on increasing knowledge about prevention of hypertension.

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