Covid-19: Outbreak to Global

2020 ◽  
Vol 18 ◽  
Author(s):  
Deepika Paliwal ◽  
Shoaib Khan ◽  
Anindita Chaki

: Corona viruses (CoV) are known respiratory pathogen causing a major pandemic such as, severe acute respiratory syndrome (SARS, Middle East respiratory syndrome (MERS) and corona virus disease 2019 COVID-19). The World Health Organization (WHO) has acknowledged that recent outbreak as a global public health emergency. Presently, the study on novel coronavirus is still in the primary stage. Based on the current data, we summarizes the clinical characteristics, pathogenesis, diagnosis, treatment and prevention of information regarding COVID-19. In this mini-review, we aims at investigating the most recent trend of COVID-19 for helping the community effectively recognize and deal with the 2019 novel coronavirus (SARS-CoV-2), and providing a reference for forthcoming studies.

2020 ◽  
Vol 10 (3) ◽  
pp. 241-252
Author(s):  
Ruchi Jain ◽  
Nilesh Jain ◽  
Surendra Kumar Jain ◽  
Ram C Dhakar

The 2019-nCoV is officially called SARS-CoV-2 and the disease is named COVID-19. The Novel coronavirus (SARS-CoV-2) caused pneumonia in Wuhan, China in December 2019 is a highly contagious disease. The World Health Organization (WHO) has declared it as a global public health emergency. This is the third serious Coronavirus outbreak in less than 20 years, following SARS in 2002–2003 and MERS in 2012. Currently, the research on novel coronavirus is still in the primary stage. It is currently believed that this deadly Coronavirus strain originated from wild animals at the Huanan market in Wuhan by Bats, snakes and pangolins have been cited as potential carriers. On the basis of current published evidence, we systematically summarize the epidemiology, clinical characteristics, diagnosis, treatment and prevention of COVID-19. This review in the hope of helping the public effectively recognize and deal with the novel coronavirus (SARS-CoV-2) and providing a reference for future studies. Keywords: SARS-CoV-2, COVID-19, Coronavirus, pneumonia, Respiratory infection


2020 ◽  
Vol 18 ◽  
Author(s):  
Rina Das ◽  
Dinesh Kumar Mehta ◽  
Meenakshi Dhanawat

Abstract:: A novel virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), appeared and expanded globally by the end of year in 2019 from Wuhan, China, causing severe acute respiratory syndrome. During its initial stage, the disease was called the novel coronavirus (2019-nCoV). It was named COVID-19 by the World Health Organization (WHO) on 11 February 2020. The WHO declared worldwide the SARS-CoV-2 virus a pandemic on March 2020. On 30 January 2020 the first case of Corona Virus Disease 2019 (COVID-19) was reported in India. Now in current situation the virus is floating in almost every part of the province and rest of the globe. -: On the basis of novel published evidences, we efficiently summarized the reported work with reference to COVID-19 epidemiology, pathogen, clinical symptoms, treatment and prevention. Using several worldwide electronic scientific databases such as Pubmed, Medline, Embase, Science direct, Scopus, etc were utilized for extensive investigation of relevant literature. -: This review is written in the hope of encouraging the people successfully with the key learning points from the underway efforts to perceive and manage SARS-CoV-2, suggesting sailent points for expanding future research.


2020 ◽  
Vol 3 (3) ◽  
pp. 01-02
Author(s):  
Khadiga Ismail

COVID-19 has high transmissibility and infectivity among human. On January 30, 2020, the World Health Organization (WHO) in an effort to slow down the global spread of the virus declared the outbreak, “A global public health emergency of international concern". The skin manifestations of the novel coronavirus COVID-19 were not recognized at the early stages of the pandemic but have received much recent attention in scientific journals. Reported manifestations range from pseudo-chilblains to a morbilliform (measles-like) exanthem, urticaria, vesicular eruptions, a dengue-like petechial rash and ovate scaling macules, and plaques mimicking pityriasis rosea.


Author(s):  
Calvin W. L. Ho ◽  
Tsung-Ling Lee

Abstract Recognizing that antimicrobial resistance (AMR) poses a serious threat to global public health, the World Health Organization (WHO) has adopted a Global Action Plan (GAP) at the May 2015 World Health Assembly. Underscoring that systematic misuse and overuse of drugs in human medicine and food production is a global public health concern, the GAP-AMR urges concerted efforts across governments and private sectors, including pharmaceutical industry, medical professionals, agricultural industry, among others. The GAP has a threefold aim: (1) to ensure a continuous use of effective and safe medicines for treatment and prevention of infectious diseases; (2) to encourage a responsible use of medicines; and (3) to engage countries to develop their national actions on AMR in keeping with the recommendations. While the GAP is a necessary step to enable multilateral actions, it must be supported by effective governance in order to realize the proposed aims. This chapter has a threefold purpose: (1) To identify regulatory principles embedded in key WHO documents relating to AMR and the GAP-AMR; (2) To consider the legal and regulatory actions or interventions that countries could use to strengthen their regulatory lever for AMR containment; and (3) To highlight the crucial role of the regulatory lever in enabling other levers under a whole-of-system approach. Effective AMR containment requires a clearer understanding of how the regulatory lever could be implemented or enabled within health systems, as well as how it underscores and interacts with other levers within a whole-of-system approach.


2020 ◽  
Vol 22 (4) ◽  
pp. 630-652
Author(s):  
Puneeta Ajmera ◽  
Jaseela Majeed ◽  
Ramesh K. Goyal ◽  
Sheetal Yadav ◽  
Debraj Mukhopadhyay

World Health Organization (WHO) has declared the recent outbreak of coronavirus disease (COVID-19) a Pandemic and a global public health emergency. The eventual scope and consequences of this outbreak are uncertain at present as the condition is swiftly evolving. The purpose of this article is to cumulate existing published data and researches, identify the challenges with reference to India and develop a comprehensive preventive plan to prevent the spread of this deadly pandemic. The authors explored WHO situation dashboards, the web portal of Ministry of Health and Family Welfare of India and press reports of different countries, published literature on coronavirus transmission, textbooks, scientific and medical journals and several other sources to identify ongoing challenges in the fight against COVID-19 in India. After an exhaustive literature search, 15 ongoing challenges in the fight against novel COVID-19 especially with reference to India have been identified. After a thorough analysis of all these challenges along with the lessons from the International community, a preventive plan has been established to be devised by different agencies from our personal perspectives to overcome the challenges which may assist decision-makers in the prevention and control of COVID-19 in India.


2020 ◽  
Author(s):  
Qin Chen

UNSTRUCTURED The outbreak of novel coronavirus pneumonia has been declared a public health emergency of international concern by World Health Organization since January 30, 2020 and the new coronavirus pneumonia was named Corona Virus Disease 2019(COVID-19) in February 11th. Novel coronavirus has been effectively controlled in China, but has spread worldwide and been epidemic in some countries. By March 30th, more than 600 thousand people were confirmed infected in areas other than China, and increased by more than 50 thousand people per day3. Our hospital is a district-level public hospital directly under the Jinniu District Government. Since February 5, our hospital has been listed by the Chengdu Municipal Government as the primary designated medical unit for treating new crown patients in Jinniu District.Recently, how to deal with COVID-19 more effectively and interrupt the transmission has become the concern of medical staff. Now we will share our experience on COVID-19 with you.


Author(s):  
Hui Yang ◽  
Yingying Lyu ◽  
Fajian Hou

Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak began in December 2019, causing the illness known as the novel coronavirus disease 2019 (COVID-19). The virus spread rapidly worldwide to become a global public health emergency. As of 15 November 2020, more than 53 million confirmed cases and over one million deaths worldwide have been reported (World Health Organization, 2020). The SARS-CoV-2 genome was sequenced and studies are ongoing to further understand the epidemiology, clinical manifestations, etiological structure, cellular receptor angiotensin II converting enzyme (ACE2), and intracellular replication process of the virus. Currently, thousands of clinical trials related to SARS-CoV-2 are underway (https://clinicaltrials.gov/). However, no vaccines or drugs have yet been approved, until very recently, for direct treatment or prevention of COVID-19 and only supportive treatment has been applied clinically. This review will discuss the possible mechanism of the innate immune response to SARS-CoV-2 infection and provide insight into the development of related therapeutics.


Author(s):  
Abhishek Kumar Soni

The 2019 novel coronavirus (previously 2019-nCoV) or coronavirus infectious disease 2019 (COVID-19) outbreak has been summarized as on March 29, 2020. COVID-19 is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2 (SERS-CoV-2). The disease was first seen during an outbreak in Wuhan, China and continuous spreading from human to human around the sphere. The disease is uncontrolled and increasing the death toll through. The world is facing a global challenge to protect human lives caused by coronavirus outbreak. The number of infected patients is increasing day by day due to COVID-19 as a pandemic. The world health organization (WHO) has declared global public health emergency on January 30, 2020. The disease has been spread around 201 countries with total confirmed cases 634835 and death cases 29891 as on March 29, 2020. The goal of this review to summaries and update the clinical/medical features and suggestions for diagnosis of the COVID-19 as a pandemic. The discussion of the various therapeutic algorithms, risk, prevention and control based on the latest reports has been provided.


2021 ◽  
pp. 1-3
Author(s):  
Rajvi Dave ◽  
Bhavesh Jarwani ◽  
Sanket Nandani ◽  
Tirth Patel

BACKGROUND : Coronavirus disease 2019(COVID 19) is an illness which is associated with the novel coronavirus known as severe acute respiratory syndrome coronavirus 2(SARS-CoV -2).On December 2019, Wuhan City in China, became the epicenter of this pandemic. On March 17 2020 Ahmedabad reported its first positive case. On January 2020, Chinese scientists identified this as a novel coronavirus, temporarily labelled as, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1]. Its name was then changed to coronavirus disease 2019 (COVID-19) by the World Health Organization in February 2020 as the disease spread worldwide [2]. COVID 19 pandemic has posed a huge threat to global public health .The clinical features of COVID-19 are very diverse, ranging from asymptomatic state to acute respiratory distress syndrome and multi organ dysfunction. The common clinical features include fever, cough, sore throat, headache, fatigue, headache, myalgia and breathlessness. Emergency workers carry a huge responsibility in this pandemic. We have to provide early triage and management of patients with suspected or confirmed infection in which inflammatory markers play an important role. More importantly we have to try to prevent the spread of infection and also be prepared to tackle such large footfalls in ED


2020 ◽  
Vol 11 (6) ◽  
pp. 9-14
Author(s):  
Ravichandra Ravi ◽  
Srividya Athkuri ◽  
Charishma Chowdary Ponugubati ◽  
Roopesh Borugadda ◽  
Sahithi Pamidimukkala ◽  
...  

Background: The pandemic caused by novel coronavirus (SARS-CoV-2) in Wuhan, China, in December 2019 is a highly infectious disease. The World Health Organization (WHO) has declared the outbreak of Corona Virus Diseases (COVID 19) as a global public health emergency. Currently, research on novel coronaviruses is still in the primary stage. Aims and Objective: The aim of this study is to assess knowledge and awareness on the usage of mouth masks among dental fraternity during this pandemic COVID-19. Materials and Methods: A total of 507 dentists from the Andhra Pradesh (India) region completed a questionnaire-based survey on knowledge, awareness, and infection control measures, such as usage of mouth masks during the pandemic COVID -19. The questionnaire was tailored from the guidance and the information provided for healthcare workers issued by the US Centres for Disease Control and Prevention (CDC). A suitable sampling method was used for the collection of data, and the distribution of responses was presented as percentages. Explanatory statistics were performed for all groups based on the percentage of correct responses. Results: A total of 530 participated in the survey, out of which 507 dentists completely answered the survey, and the response rate was 95.6%. Among the respondents, general practitioners and postgraduates accounted for 58.8% and 41.2%, respectively. There was a statistically significant difference for all the questions solicited among the respondents. General or private practitioners seem to be more aware than postgraduates, as they have answered correctly (>65%) for almost all the questions. Conclusion: The inputs from the study help us to throw some light and fill up space where required. There is a specific and strong need to implement periodic educational programmes and training sessions on infection control practices for COVID-19 among dentists in particular.


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