scholarly journals PREVALENCE OF OVERWEIGHT AND OBESITY AND ASSESSMENT OF LIPID PROFILE AND FASTING BLOOD GLUCOSE LEVELS AMONG FEMALE PREMEDICAL STUDENTS AT NNAMDI AZIKIWE UNIVERSITY, NNEWI CAMPUS, NIGERIA

2018 ◽  
Vol 11 (7) ◽  
pp. 481
Author(s):  
Emmanuel Ikechukwu Onwubuya ◽  
Nkiruka Rose Ukibe ◽  
Ofia Anya Kalu ◽  
Obiageli Fidelia Emelumadu ◽  
Ifeoma Nwamaka Monago ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Significant Risk ◽  
Density Lipoprotein ◽  
Significant Risk Factor ◽  
Overweight And Obesity ◽  
Lipoprotein Cholesterol ◽  
Public Health Issue ◽  
Premedical Students ◽  
And Control

Objective: Obesity is a major public health issue and a significant risk factor for metabolic disorders. This prospective study was aimed at evaluating the prevalence of obesity, lipid profiles, and fasting blood glucose (FBG) among female premedical students of NAU, Nnewi Campus, Nigeria.Methods: A total of 320 female premedical students aged 18–35 years were recruited. The participants were classified using Body mass index(BMI) as underweight (35), overweight (104), obese (26), and control (155). FBG and lipids were estimated using enzymatic methods. Obesity was assessed using BMI and waist circumference. Blood pressure (BP) was measured using accoson sphygmomanometer.Results: The study observed 10.9% underweight, 32.5% overweight, and 8.1% obesity. Underweight was higher among participants aged 18–23 years (48.6%), while overweight and obesity were more among participants aged 24–29 years (57.7% and 53.8%). Central obesity was observed in 28.8% of participants. BPs were higher in obese and overweight participants than in other groups. FBG was higher in obese and overweight participants than in other groups. The mean total cholesterol (TC) and low-density lipoprotein cholesterol (LDLC) were significantly higher in obese and overweight participants, while high-density lipoprotein cholesterol (HDLC) was significantly lower when compared to their corresponding values in underweight and control participants (p<0.05).Conclusions: The study showed high prevalence of underweight, overweight, and obesity among the study population. The significantly higher levels of TC, LDLC, FBG, and elevated BP with significantly lower HDLC in overweight and obese participants compared to control suggests a possible risk of dyslipidemia, diabetes mellitus, and hypertension. The significant correlation between the lipid parameters, FBG, and anthropometric indices suggests high-risk cardiovascular disorders.

scholarly journals ASSOCIATION BETWEEN BLOOD LIPID PROFILE AND BLOOD GLUCOSE LEVELS IN MEN WITH CORONARY HEART DISEASE, METABOLIC SYNDROME, AND TYPE 2 DIABETES MELLITUS

2013 ◽  
Vol 12 (5) ◽  
pp. 29-33
Author(s):  
S. A. Matveeva
Keyword(s):  
Blood Glucose ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Blood Lipid ◽  
Lipoprotein Cholesterol ◽  
Blood Lipid Profile ◽  
Glucose Levels ◽  
Blood Glucose Levels

Aim.To study the associations between blood lipid profile and blood glucose levels in men with coronary heart disease (CHD), stable effort angina (SEA), metabolic syndrome (MS), and Type 2 diabetes mellitus (DM-2).Material and methods.The study included 82 men (mean age 50,5±0,9 years) with CHD, Functional Class I–III SEA, MS, and DM-2. The following lipid profile parameters were assessed: total cholesterol (TCH), triglycerides (TG), low-density lipoprotein cholesterol (LDL–CH), very low-density lipoprotein cholesterol (VLDL–CH), high-density lipoprotein cholesterol (HDL–CH), atherogenic index (AI), and triglyceride index (TGI), together with fasting blood glucose.Results.There were positive (direct) associations between higher levels (>90th percentile) of lipid profile parameters (TCH, TG, LDL–CH, VLDL– CH, HDL–CH, AI, TGI) and blood glucose, as well as between lower levels (≤10th percentile) of lipid profile parameters (TCH, TG, LDL–CH, VLDL– CH, AI, TGI) and blood glucose. At the same time, there were negative (inverse) associations between lower lipid levels (≤10th percentile of TCH, TG, LDL–CH, VLDL–CH, HDL–CH, AI, TGI) and higher glucose levels (>90th percentile), as well as between higher lipid levels (>90th percentile of TCH, TG, LDL–CH, VLDL–CH, HDL–CH, AI, TGI) and lower glucose levels (≤10th percentile).Conclusion.Dyslipidemia and hyperglycemia demonstrate synergetic proatherogenic effects in patients with CHD, SEA, MS, and DM-2, as suggested by significant heterogeneous (direct and inverse) associations between lipid profile parameters and fasting blood glucose. The results obtained provide an opportunity for the assessment of risk levels, prognosis, and need for pharmacological prevention and treatment in patients with combined cardiovascular pathology. 

scholarly journals Rising Thyroid Disorders Among Type 2 Diabetic Mellitus Patients: Case-Control Study

2018 ◽  
Vol 10 (8) ◽  
pp. 61
Author(s):  
Abdulbari Bener ◽  
Abdulla O.A.A. Al-Hamaq ◽  
Cem Cahit Barisik ◽  
Yasar Özdenkaya ◽  
Mustafa Öztürk
Keyword(s):  
Blood Glucose ◽  
Family History ◽  
Thyroid Dysfunction ◽  
Thyroid Nodules ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
History Of ◽  
And Control ◽  
Control Study

AIM: The objective of study to explore the association between thyroid dysfunction and Type 2 diabetes mellitus (T2DM) related to family history and co-morbid conditions.METHODS: This was a case and control study, 762 T2DM patients and 762 control study participants were enrolled, aged between 25 and 65 years. The study based on biochemistry parameters included: fasting blood glucose levels (FBG), glycosylated hemoglobin (HbA1c), serum cholesterol, triglycerides, high density lipoprotein (HDL), low density lipoprotein (LDL), thyroid stimulating hormone (TSH), T3, and T4.RESULTS: There were statistically significant differences between T2DM patients and control subjects regarding BMI, physical activity, smoking, metabolic syndrome, hypertension, family history thyroid nodules, and number of sleeping hours. The study found statistically significant differences between T2DM and control subjects on calcium (p=0.028), magnesium (p&lt;0.001), potassium (p&lt;0.001), phosphorous (p=0.038), fasting blood glucose (p&lt;0.001), HbA1c (p&lt;0.001), LDL (p=0.002), albumin (p&lt;0.001), billirubin (p=0.015), triglyceride (p&lt;0.001), SBP (p=0.009) and, DBP (p=0.002), TSH (p&lt;0.001), T3 (p&lt;0.001), and T4 (p&lt;0.001). There were statistically significant differences between subjects with and those without thyroid nodules for calcium (p&lt;0.001), magnesium (p&lt;0.001), phosphorous (p=0.022), HDL (p=0.050), TSH (p&lt;0.001), T3 (p&lt;0.001), and T4 (p&lt;0.001). Multivariable stepwise logistic regression analysis showed that TSH mIU/L ( &lt;0.001), HbA1c ( p&lt; 0.001),  family history of thyroid (p&lt; 0.001), Waist circumference, (p&lt;0.001), SBP mmHg (p= 0.002), [DBP mmHg ( p= 0.003), BMI (p= 0.006), Serum Calcium level (mmol/L) (p &lt;0.001], and family history of DM ( p= 0.015) were considered at higher risk as a predictors of thyroid amongT2DM patients.CONCLUSION: The study found a high prevalence of thyroid dysfunction in Turkish T2DM patients compared to the general population. This study suggests that obesity, HbA1c, the environment, and genetic susceptibility among T2DM, may increase the risk of thyroid disease and cancer.

scholarly journals Associations of dietary polyunsaturated fatty acids with dyslipidemia among the U.S. adults: the findings from NHANES 2009-2016

2021 ◽  
pp. 1-28
Author(s):  
Jiawei Zhou ◽  
Lixin Cai ◽  
Senmiao Ni ◽  
Zihang Zhong ◽  
Min Yang ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Low Density Lipoprotein ◽  
Significant Risk ◽  
Density Lipoprotein ◽  
Significant Risk Factor ◽  
Lipoprotein Cholesterol ◽  
Inverse Association ◽  
Dietary Pufa ◽  
Pufa Intake

Abstract Dyslipidemia, a significant risk factor of cardiovascular disease, is threatening human health worldwide with a high economic burden. Polyunsaturated fatty acids (PUFAs) are crucial long-chain fatty acids for triglyceride synthesis and removal, potentially decreasing dyslipidemia risk. We examined dyslipidemia prevalence among 15,244 adults aged ≥20 years from NHANES 2009-2016. The dyslipidemia was defined as total cholesterol ≥240 mg/dL, or high-density lipoprotein cholesterol <40 mg/dL/50 mg/dL for males/females respectively, or low-density lipoprotein cholesterol ≥160 mg/dL, or triglyceride ≥200 mg/dL, or taking lipid-modifying medications. We measured the daily PUFA intake using a 24-h dietary recall. Demographics, social-economics, and lifestyle factors were collected using questionnaires/interviews. Additionally, we measured selenium and mercury levels in the whole blood. Logistic regression models were used to examine the association between PUFAs and dyslipidemia. The unweighted and weighted dyslipidemia prevalences were 72.4% and 71.0%, respectively. When grouped into tertiles, PUFA intake above 19.524 g/day was associated with an independent 19% decrease in dyslipidemia risk [O.R.=0.81(95%C.I.: 0.71-0.94)] compared with the lowest tertile (PUFA intake ≤12.349 g/day). A threshold inverse association was further determined by the restricted cubic spline analysis. When PUFA intake was increased to its turning point, i.e., 19 g/day, the lower nadir risk for dyslipidemia was obtained [O.R.=0.72(95% C.I.: 0.56-0.89)]. When the exposure was the sum of α-linolenic acid and octadecatetraenoic acid, the inverse linear association remained. Dietary PUFA intake is a beneficial factor for dyslipidemia among American adults, independent of many potential confounders, including mercury and selenium. Future prospective studies are warranted.

Pediatric Victims of Unexplained Stroke and Their Families: Familial Lipid and Lipoprotein Abnormalities

PEDIATRICS ◽  
1982 ◽  
Vol 69 (3) ◽  
pp. 308-316
Author(s):  
Charles J. Glueck ◽  
Stephen R. Daniels ◽  
Stephen Bates ◽  
Corning Benton ◽  
Trent Tracy ◽  
...  
Keyword(s):  
Familial Aggregation ◽  
Low Density Lipoprotein ◽  
Significant Risk ◽  
Density Lipoprotein ◽  
Significant Risk Factor ◽  
Lipoprotein Cholesterol ◽  
Pediatric Stroke ◽  
Ischemic Cerebrovascular Disease ◽  
Premature Coronary Heart Disease ◽  
Low Levels

The finding of low levels of high-density lipoprotein cholesterol (C-HDL) and/or high levels of triglyceride in several children with "unexplained" ischemic cerebrovascular accidents led to a systematic review of lipids and lipoproteins in 11 pediatric victims of unexplained stroke and their families. Each of the children, 1 to 17 years of age, had an acute, nonhemorrhagic cerebrovascular accident documented by symptoms, signs, history, physical examination, and laboratory radiographic studies; no known causes or strong preclisposing factors were elicited. Of the 11 pediatric stroke probands, only one had normal lipid and lipoprotein levels; five had low C-HDL levels alone, two had elevated levels of plasma triglycerides with low C-HDL levels, two had high levels of triglycerides with normal C-HDL levels, and one had high levels of low-density lipoprotein cholesterol (C-LDL) alone. A consistent trend toward familial clustering of low C-HDL, elevated triglyceride, and/or C-LDL levels was observed. Nine of the 11 kindreds had two generation parent:child stroke proband, or parent:child clustering of elevated triglyceride and/or depressed C-HDL levels, whereas one parent:child stroke proband pair had elevated levels of C-LDL. In five of nine kindreds for whom siblings of the pediatric stroke probands were available for testing, there were low C-HDL and/or high triglyceride levels in otherwise healthy and entirely asymptomatic siblings. In nine of the 11 kindreds premature coronary heart disease and/or ischemic cerebrovascular disease was observed in the probands' adult relatives. We speculate that familial lipoprotein abnormalities, particularly those involving low levels of C-HDL and/or high levels of triglycerides, may mediate occlusive cerebrovascular arteriosclerosis, and thus may predispose children to ischemic cerebrovascular strokes. The apparent association of lipoproteins and ischemic strokes in children and their families merits further exploration with a particular focus on familial aggregation of low C-HDL levels, already known to be a significant risk factor for ischemic cerebrovascular and cardiovascular disease in adults.

P008 Lipid profile disorders in children and adolescents with Juvenile Idiopathic Arthritis

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_5) ◽  
Author(s):  
Samah I Nasef ◽  
Sara S I M Abouzied ◽  
Samar M Elfiky ◽  
A Zeiton
Keyword(s):  
Risk Factor ◽  
Juvenile Idiopathic Arthritis ◽  
Disease Activity ◽  
Lipid Profile ◽  
Children And Adolescents ◽  
Significant Risk ◽  
Density Lipoprotein ◽  
Significant Risk Factor ◽  
Lipoprotein Cholesterol ◽  
Active Disease

Abstract Background Dyslipidaemia is a well-recognized risk factor for cardiovascular diseases. Inflammation has been linked to alterations of the lipid profile and accelerated atherogenesis. Lipid profile disorders are one of the most studied problems in adult patients with rheumatoid arthritis. However, few studies addressed this problem in juvenile idiopathic arthritis patients. The objective is to describe the prevalence of dyslipidaemia in children and adolescents with Juvenile Idiopathic Arthritis. Methods One hundred patients diagnosed with JIA were included. Exclusion criteria were patients previously treated with lipid lowering drugs, history of familial dyslipidaemia, thyroid disease, and diabetes mellitus. Data obtained from the patients included age, gender, duration of disease and body mass index (BMI). Fasting lipid profiles included triglycerides (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL) and high-density lipoprotein cholesterol (HDL). Fasting lipid profiles were measured after overnight fasting and consumption of normal diet for previous 2 days (without fat restriction). Normal values were considered according to reference values. Other laboratory tests included ESR, CRP, RF, and ANA. Disease activity was classified according to juvenile disease activity score (JADAS-27). Results The study included 100 JIA patients. Out of them, 78 patients were females, 51 patients had RF negative Polyarticular type, 20 patients had RF positive polyarticular type, 24 patients had systemic onset type and 5 patients had extended oligoarticular type. Mean age was 11.55 ± 4.02 years. Mean age at disease onset was 8.3 ± 1.5 years. Mean disease duration was 4.30 ± 1.7 years. Mean BMI was 22.3 ± 7.32 Kg/m2. Mean ESR was 31.24 ± 10.4 mm/h. Mean CRP level was 7.56 ± 4.61 mg/dl. About 20% of the patients had positive RF and about 8% had positive ANA. Twenty-six patients had active disease. Mean TC was 153.818 ± 29.8 mg/dl, mean HDL was 47.65 ± 16.8 mg/dl, mean LDL was 87.43 ± 28.1 and mean TG was 89.04 ± 26.1 mg/dl. The most common lipid abnormality was disturbed HDL, it was found in 40% patients followed by disturbed TG in 21% of patients. Abnormal TC was found in 15% of the patients and abnormal LDL was found in 12% of the patients. Active disease was significantly associated with abnormal TC, HDL, and TG levels (P = 0.03*), (P = 0.03*) and (P = 0.04*) respectively. No associations were found with ESR or CRP levels. Active disease is a significant risk factor for abnormal TG with increased risk of abnormal TG by 2.9 among cases with active disease than cases with inactive disease. The overall percent predicted was 73.8%. Conclusion Children and adolescents with JIA showed significant lipid profile abnormalities. Abnormal TC, HDL and TG are significantly associated with active disease. Active disease is a significant risk factor for abnormal TG. Therefore, we recommend monitoring lipid profile in JIA patients regularly to reduce the long-term risk of CVD.

scholarly journals Six Air Pollutants Associated With Increased Risk of Thyroid Nodules: A Study of 4.9 Million Chinese Adults

2021 ◽  
Vol 12 ◽  
Author(s):  
Yunjing Zhang ◽  
Kai Wang ◽  
Wei Qin ◽  
Cheng Jin ◽  
Yiqing Song ◽  
...  
Keyword(s):  
Sex Education ◽  
Air Pollutants ◽  
Thyroid Nodules ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Public Health Issue ◽  
Outdoor Air ◽  
Increased Risk ◽  
Urine Iodine

BackgroundThyroid nodules has become a significant public health issue worldwide with a rapidly increasing prevalence. However, its association with outdoor air pollution remains poorly understood. We aim to investigate the relationship between six outdoor air pollutants (PM2.5, PM10, NO2, SO2, CO, and O3) and the risk of thyroid nodules.MethodsWe utilized a database including 4,920,536 participants who attended the annual physical examinations in the Meinian HealthCare Screening Center in 157 Chinese cities in 2017. City-specific concentrations of six pollutants (PM2.5, PM10, NO2, SO2, CO, and O3) from 2015 to 2017 were estimated based on the China’s National Urban Air Quality Real Time Publishing Platform. Thyroid nodule was measured with ultrasound. Multivariable Logistic regression was used to examine the associations between air pollutants and thyroid nodules with adjustment for age, sex, education, smoking, body mass index, fasting blood glucose, triglyceride, low density lipoprotein cholesterol, high density lipoprotein cholesterol, urine iodine, gross domestic product, and thyroid stimulating hormone. We conducted stratified analyses to investigate potential effect modification by sex, age, and urine iodine groups.ResultsApproximately 38% of the participants (1,869,742) were diagnosed with thyroid nodules. Each of the six air pollutants was significantly and linearly associated with the risk for thyroid nodules. The adjusted odds ratios [95% CI] for every increase of 10 μg/m3 for PM2.5, PM10, NO2, SO2, and O3 were 1.062 [1.061, 1.064], 1.04 [1.03, 1.04], 1.10 [1.09, 1.10], 1.11 [1.11, 1.12], and 1.151 [1.149, 1.154], respectively; The odds ratio for each increase of 1 mg/m3 for CO was 1.50 [1.49 to 1.52]. Furthermore, these associations were significantly higher in the participants who were men, younger, or having lower urine iodine level (p &lt;0.001).ConclusionThe six air pollutants may contribute to the high prevalence of thyroid nodules in China.

scholarly journals Relationship of Glycated Haemoglobin with Lipid Profile among Patients with Type 2 Diabetes Mellitus

2017 ◽  
Vol 7 (1) ◽  
pp. 43-47 ◽  
Author(s):  
Tasrina Shamnaz Samdani ◽  
Palash Mitra ◽  
Muhammad Abdur Rahim
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Lipid Profile ◽  
Significant Positive Correlation ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Diabetic Patients ◽  
Positive Correlation

Background: Glycated hemoglobin (HbA1c) is widely used as an index of mean glycaemia, a measure of risk for the development of diabetic complications and a measure of the quality of diabetes care. Patients with type 2 diabetes have an increased prevalence of dyslipidemia. Treatment of dyslipidaemia improves cardiovascular outcomes. The aim of this study was to determine the impact of glycemic control on lipid profile.Methods: This cross-sectional study was conducted among 300 type 2 diabetic patients admitted in BIRDEM General Hospital from November 2013 to April 2015. Fasting blood samples were collected and different lipid fractions along with fasting blood glucose and HbA1c were estimated. Pearson’s correlation test was applied to evaluate the correlation between HbA1c and components of lipid profile.Results: The mean value of total cholesterol (TC), triglyceride (TG), low density lipoprotein-cholesterol (LDLC), fasting blood glucose (FBG) and HbA1c were higher and high density lipoprotein-cholesterol (HDL-C) was lower in females when compared with these values for males. HbA1c had significant positive correlation with LDL-C (p=0.045) and negative correlation with HDL-C (p=0.024). Serum lipid profile and glycaemic controls were significantly (p=0.000) better in older age group (age ? 50 years).Conclusions: Significant positive correlation of HbA1c with lipid profiles specially LDL-C suggested that HbA1c can also be used as predictor of dyslipidemia in addition to glycemic control.Birdem Med J 2017; 7(1): 43-47

scholarly journals Effect of Bushen Huoxue Prescription on Cognitive Dysfunction of KK-Ay Type 2 Diabetic Mice

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Shao-Yang Zhao ◽  
Huan-Huan Zhao ◽  
Ting-Ting Hao ◽  
Wei-Wei Li ◽  
Hao- Guo
Keyword(s):  
Cognitive Impairment ◽  
Blood Glucose ◽  
Morphological Changes ◽  
Neuroprotective Effect ◽  
Serum Insulin ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Microvascular Damage

Diabetic cognitive impairment is one of the common complications of type 2 diabetes, which can cause neurological and microvascular damage in the brain. Bushen Huoxue prescription (BSHX), a compound Chinese medicine, has been used clinically to treat diabetes-induced cognitive impairment. However, its underlying mechanisms remain unclear. In this study, KK-Ay diabetic model mouse was administered BSHX daily for 12 weeks. Bodyweight, random blood glucose (RBG), and fasting blood glucose (FBG) were measured every 4 weeks. Triglycerides (TG), cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), fasting serum insulin (FINS), and Morris water maze were tested after 12 weeks of administration. On the day of sacrifice, the hippocampus was collected for pathological staining and advanced glycation end products (AGEs) analysis to evaluate the neuroprotective effect of BSHX. Our results showed that BSHX treatment significantly ameliorated the T2DM related insults, including the increased bodyweight, blood glucose, TG, insulin levels, AGEs, the reduced HDL-C, the impaired spatial memory, and the neurological impairment. Moreover, Western blot analysis showed that increased expression of receptors of AGEs (RAGEs), inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and activation of nuclear factor-κB (NF-κB) in the hippocampus were significantly inhibited by BSHX treatment. These results indicate that BSHX can significantly ameliorate glucose and lipid metabolism dysfunction, reduce the morphological changes in hippocampus tissues, and improve the cognitive function of KK-Ay mice. These protective effects of BSHX may involve regulation of the AGEs/RAGE/NF-κB signaling pathway.

scholarly journals Study of fasting blood glucose, glycated hemoglobin and lipid profile in male and female type 2 diabetic patients

2020 ◽  
Vol 11 (1) ◽  
pp. 17-21
Author(s):  
Md Shajedul Islam ◽  
Farzana Akonjee Mishu ◽  
Mahbuba Khatun ◽  
Mohammad Amirul Islam
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Glucose ◽  
Low Density Lipoprotein ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Low Density

Background: Lipid abnormalities are more common in type 2 diabetes mellitus and are aggravated with poor glycaemic control. Lipid abnormalities play an important role in atherosclerosis, a leading cause of mortality in patients with diabetes mellitus. Thus there is a need to evaluate lipid profile and glycemic status in type 2 diabetes mellitus population and determine the major lipid risk factors for coronary artery disease. Present study focuses on the dyslipidemic pattern and glycemic status of male and female with type 2 diabetes mellitus. Methods: Total 270 patients with type 2 diabetes,age 30-60 years, both genderwere included for this crosssectional study which was carried out from January 2019 to December 2019at Bogura Diabetic Hospital, Bogura. A Structured questionnaire was prepared for each study subject after taking informed written consent. Detail personal, medical, family and socioeconomic history of study subjects were collected through history taking and review of clinical and biochemical records from the participants. Diabetic patients were diagnosed depending on history, clinical features and American Diabetes Association(ADA) criteria (2018). Fasting blood glucose, glycatedhaemoglobin (HbA1c)), fasting lipid profile were estimated in all study subjects by standard laboratory methods. Appropriate statistical tests were done. Results: Type 2 male diabetes mellitus participants showed mean fasting blood glucose, HbA1c, total cholesterol, triglyceride and low density lipoprotein cholesterol and high density lipoprotein cholesterol were 8.64 ± 3.38(mmol/L),7.86 ± 2.36(%), 233.09 ± 73.71, 198.19 ± 61.38, 152.98 ± 57.33 and 40.41 ± 5.44 (mg/ dl)respectively. Incase of female patients,fasting blood glucose, HbA1c, total cholesterol, triglyceride and low density lipoprotein cholesterol and high density lipoprotein cholesterol 8.59 ± 3.62(mmol/L),7.88 ± 2.496(%),215.899 ± 83.01, 186.18 ± 67.595, 139.10 ± 65.59 and 40.28 ± 5.66 mg/dlrespectively. There were statistically significant difference (p <0.05) of fasting blood glucose, fasting blood glucose, total cholesterol, triglyceride and low density lipoprotein cholesterol between male and female type 2 diabetic patients. Conclusion: Our study had shown that total cholesterol, triglycerides, and low-density lipoprotein levels were significantly increased in male type 2 diabetes mellitus patients, compared with female type 2 diabetes mellitus patients, while high-density lipoprotein had shown a statistically non-significant difference.This study demonstrated the existence of dyslipidemia in male diabetic population than female which is major risk factor for atherosclerosis and coronary artery disease. Birdem Med J 2021; 11(1): 17-21

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