scholarly journals Evaluation of some biological activities of phenolic compounds obtained from two Algerian medicinal plants: Mentha rotundifolia and Satureja calamintha

2020 ◽  
pp. 87-102
Author(s):  
Benfares Redhouane ◽  
Boudjema Khaled ◽  
Behlali Hadjira ◽  
Imedjdouben Imene ◽  
Kennas Abderrezak ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Biological Activities ◽  
Plant Secondary Metabolites ◽  
Antimicrobial Properties ◽  
Antibacterial Activities ◽  
Microbial Strains ◽  
High Concentrations

In this work phytochemical characterization of two medicinal plants from Lamiaceae family, Mentha rotundifolia and Satureja calamintha, has been carried out. Extracts obtained with different solvents were screened for different plant secondary metabolites and were biologically characterized by defining their antiradical and antibacterial activities. Phytochemical screening of M. rotundifolia and S. calamintha confirmed their richness in different secondary metabolites. The determination of phenolic compounds revealed high polyphenols contents in water: methanol (30:70) extracts with concentrations of 20.64?1.74 mg EAG/g DW and 13.45?0.91 mg EAG/g DW for M. rotundifolia and S. calamintha, respectively. These extracts were also characterized by high concentrations of flavonoids (Mentha rotundifolia 12.33?1.58 mg EQ/g DW, Satureja calamintha 7.11?0.02 mg EQ/g DW). Furthermore, the water: methanol (30:70) extract of M. rotundifolia was the most effective in inhibiting free radicals. Recorded inhibition diameters for both plant samples and tested microbial strains ranged from 6.66 mm to 13.66 mm. Presented results confirmed that tested indigenous Algerian plants are favorable sources of polyphenols with antioxidant and antimicrobial properties.

scholarly journals Antimicrobial Efficiency of Aloe arborescens and Aloe barbadensis Natural and Commercial Products

Plants ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 92
Author(s):  
Kaja Kupnik ◽  
Mateja Primožič ◽  
Željko Knez ◽  
Maja Leitgeb
Keyword(s):  
Biological Activities ◽  
Antimicrobial Properties ◽  
Aloe Barbadensis ◽  
Commercial Products ◽  
Qualitative And Quantitative ◽  
Gram Positive Bacteria ◽  
Antimicrobial Efficiency ◽  
Aloe Arborescens ◽  
Pharmaceutical Industries

Nowadays, there are many commercial products from natural resources on the market, but they still have many additives to increase their biological activities. On the other hand, there is particular interest in natural sources that would have antimicrobial properties themselves and would inhibit the growth and the reproduction of opportunistic microorganisms. Therefore, a comparative antimicrobial study of natural samples of aloe and its commercial products was performed. Qualitative and quantitative determination of antimicrobial efficiency of Aloe arborescens and Aloe barbadensis and its commercial products on fungi, Gram-negative, and Gram-positive bacteria was performed. Samples exhibited antimicrobial activity and slowed down the growth of all tested microorganisms. Research has shown that natural juices and gels of A. arborescens and A. barbadensis are at higher added concentrations comparable to commercial aloe products, especially against microbial cultures of Bacillus cereus, Candida albicans, and Pseudomonas aeruginosa, whose growths were completely inhibited at a microbial concentration of 600 μg/mL. Of particular importance are the findings of the good antimicrobial efficacy of fresh juice and gel of A. arborescens on tested microorganisms, which is less known and less researched. These results show great potential of A. arborescens for further use in medicine, cosmetics, food, and pharmaceutical industries.

scholarly journals Chemical composition, antimicrobial activity and biological properties of essential oils

2015 ◽  
Vol 9 (2) ◽  
pp. 9-13 ◽  
Author(s):  
Amir Hossein Saeidnejad ◽  
Peyman Rajaei
Keyword(s):  
Chemical Composition ◽  
Medicinal Plants ◽  
Essential Oil ◽  
Essential Oils ◽  
Antimicrobial Properties ◽  
Biological Properties ◽  
Antioxidant Agents ◽  
Ancient Times ◽  
High Concentrations ◽  
Oil Repellent

Essential oils constitute a heterogeneous collection of chemical compounds. Their main characteristics are that they all synthesized by plants and are volatile and mostly soluble in ethanol. They have traditionally been obtained from plants and they have been widely used for insecticidal, medicinal and cosmetic purposes. Essential oils contains about 20–60 components at quite different concentrations and they are characterized by two or three major components at fairly high concentrations. Lately, the essential oils and various extracts of plants have gained special interest as sources of natural antimicrobial and antioxidant agents because of the resistance to antibiotics that some microorganisms have acquired and the possible toxicities of the synthetic antioxidants. Spices consumed daily in different types of food to improve flavors, since ancient times, are well known for their antioxidant and antimicrobial properties. During recent decades, numerous numbers of plants have been monitored for their possible role as repellents and insecticides. In this review, the chemical composition profile of some important medicinal plants was evaluated, then antimicrobial properties of a number of essential oils was compared. Antioxidant activity of some essential oils was also considered. Finally, essential oil repellent properties an an important characteristics was evaluated. Further investigation for available data related to the other biological properties of medicinal plants essential oil is recommended.DOI: http://dx.doi.org/10.3126/ijls.v9i2.12043 International Journal of Life Sciences 9 (2) : 2015; 9-13

scholarly journals Pharmacology and Phytochemistry of Ecuadorian Medicinal Plants: An Update and Perspectives

2021 ◽  
Vol 14 (11) ◽  
pp. 1145
Author(s):  
Chabaco Armijos ◽  
Jorge Ramírez ◽  
Melissa Salinas ◽  
Giovanni Vidari ◽  
Alírica I. Suárez
Keyword(s):  
Chemical Composition ◽  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Essential Oils ◽  
Volatile Compounds ◽  
Biological Activities ◽  
Indigenous Communities ◽  
Therapeutic Agents ◽  
Practical Applications ◽  
Pharmacological Studies

The use of plants as therapeutic agents is part of the traditional medicine that is practiced by many indigenous communities in Ecuador. The aim of this study was to update a review published in 2016 by including the studies that were carried out in the period 2016–July 2021 on about 120 Ecuadorian medicinal plants. Relevant data on raw extracts and isolated secondary metabolites were retrieved from different databases, resulting in 104 references. They included phytochemical and pharmacological studies on several non-volatile compounds, as well as the chemical composition of essential oils (EOs). The tested biological activities are also reported. The potential of Ecuadorian plants as sources of products for practical applications in different fields, as well the perspectives of future investigations, are discussed in the last part of the review.

scholarly journals Emerging Technologies for the Extraction of Marine Phenolics: Opportunities and Challenges

Marine Drugs ◽  
2020 ◽  
Vol 18 (8) ◽  
pp. 389 ◽  
Author(s):  
Adane Tilahun Getachew ◽  
Charlotte Jacobsen ◽  
Susan Løvstad Holdt
Keyword(s):  
Phenolic Compounds ◽  
Secondary Metabolites ◽  
Organic Solvents ◽  
Emerging Technologies ◽  
Biological Activities ◽  
Extraction Yield ◽  
Ultrasound Assisted Extraction ◽  
Assisted Extraction ◽  
Challenging Environment ◽  
Pharmaceutical Industries

Natural phenolic compounds are important classes of plant, microorganism, and algal secondary metabolites. They have well-documented beneficial biological activities. The marine environment is less explored than other environments but have huge potential for the discovery of new unique compounds with potential applications in, e.g., food, cosmetics, and pharmaceutical industries. To survive in a very harsh and challenging environment, marine organisms like several seaweed (macroalgae) species produce and accumulate several secondary metabolites, including marine phenolics in the cells. Traditionally, these compounds were extracted from their sample matrix using organic solvents. This conventional extraction method had several drawbacks such as a long extraction time, low extraction yield, co-extraction of other compounds, and usage of a huge volume of one or more organic solvents, which consequently results in environmental pollution. To mitigate these drawbacks, newly emerging technologies, such as enzyme-assisted extraction (EAE), microwave-assisted extraction (MAE), ultrasound-assisted extraction (UAE), pressurized liquid extraction (PLE), and supercritical fluid extraction (SFE) have received huge interest from researchers around the world. Therefore, in this review, the most recent and emerging technologies are discussed for the extraction of marine phenolic compounds of interest for their antioxidant and other bioactivity in, e.g., cosmetic and food industry. Moreover, the opportunities and the bottleneck for upscaling of these technologies are also presented.

scholarly journals Microbiological and Antioxidant Activity of Phenolic Compounds in Olive Leaf Extract

Molecules ◽  
2020 ◽  
Vol 25 (24) ◽  
pp. 5946
Author(s):  
Dragana Borjan ◽  
Maja Leitgeb ◽  
Željko Knez ◽  
Maša Knez Hrnčič
Keyword(s):  
Phenolic Compounds ◽  
Leaf Extract ◽  
Biological Activities ◽  
Olive Leaf ◽  
Olive Leaves ◽  
Olive Leaf Extract ◽  
Antimicrobial Potential ◽  
Isolation And Characterization ◽  
Wide Range

According to many reports, phenolic compounds isolated from olive leaves have very good biological activities, especially antimicrobial. Presently, the resistance of microorganisms to antibiotics is greater than ever. Therefore, there are numerous recent papers about alternative solutions for inhibiting their influence on human health. Olive leaf is studied as an important source of antimicrobials with low cost and used in medicine. Numerous publications on involving green technologies for isolation of active compounds from olive leaves have appeared over the past few decades. The present review reports on current knowledge of the most isolated phenolic compounds from olive leaf extract as well as methods for their isolation and characterization. This paper uses recent research findings with a wide range of study models to describe the antimicrobial potential of phenolic compounds. It also describes the vast range of information about methods for determination of antimicrobial potential focusing on effects on different microbes. Additionally, it serves to highlight the role of olive leaf extract as an antioxidants and presents methods for determination of antioxidant potential. Furthermore, it provides an overview of presence of enzymes. The significance of olive leaves as industrial and agricultural waste is emphasized by means of explaining their availability, therapeutic and nutritional effects, and research conducted on this field.

scholarly journals Spectroscopic determination of ecologically relevant plant secondary metabolites

2016 ◽  
Vol 7 (11) ◽  
pp. 1402-1412 ◽  
Author(s):  
John J. Couture ◽  
Aditya Singh ◽  
Kennedy F. Rubert‐Nason ◽  
Shawn P. Serbin ◽  
Richard L. Lindroth ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Plant Secondary Metabolites ◽  
Spectroscopic Determination

scholarly journals Plant Secondary Metabolites Produced in Response to Abiotic Stresses Has Potential Application in Pharmaceutical Product Development

Molecules ◽  
2022 ◽  
Vol 27 (1) ◽  
pp. 313
Author(s):  
Karma Yeshi ◽  
Darren Crayn ◽  
Edita Ritmejerytė ◽  
Phurpa Wangchuk
Keyword(s):  
Abiotic Stress ◽  
Drug Discovery ◽  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Natural Habitat ◽  
Plant Secondary Metabolites ◽  
Sample Collection ◽  
Pharmacological Activities ◽  
Alternative Source ◽  
Pharmaceutical Industries

Plant secondary metabolites (PSMs) are vital for human health and constitute the skeletal framework of many pharmaceutical drugs. Indeed, more than 25% of the existing drugs belong to PSMs. One of the continuing challenges for drug discovery and pharmaceutical industries is gaining access to natural products, including medicinal plants. This bottleneck is heightened for endangered species prohibited for large sample collection, even if they show biological hits. While cultivating the pharmaceutically interesting plant species may be a solution, it is not always possible to grow the organism outside its natural habitat. Plants affected by abiotic stress present a potential alternative source for drug discovery. In order to overcome abiotic environmental stressors, plants may mount a defense response by producing a diversity of PSMs to avoid cells and tissue damage. Plants either synthesize new chemicals or increase the concentration (in most instances) of existing chemicals, including the prominent bioactive lead compounds morphine, camptothecin, catharanthine, epicatechin-3-gallate (EGCG), quercetin, resveratrol, and kaempferol. Most PSMs produced under various abiotic stress conditions are plant defense chemicals and are functionally anti-inflammatory and antioxidative. The major PSM groups are terpenoids, followed by alkaloids and phenolic compounds. We have searched the literature on plants affected by abiotic stress (primarily studied in the simulated growth conditions) and their PSMs (including pharmacological activities) from PubMed, Scopus, MEDLINE Ovid, Google Scholar, Databases, and journal websites. We used search keywords: “stress-affected plants,” “plant secondary metabolites, “abiotic stress,” “climatic influence,” “pharmacological activities,” “bioactive compounds,” “drug discovery,” and “medicinal plants” and retrieved published literature between 1973 to 2021. This review provides an overview of variation in bioactive phytochemical production in plants under various abiotic stress and their potential in the biodiscovery of therapeutic drugs. We excluded studies on the effects of biotic stress on PSMs.

scholarly journals Phytochemicals: Extraction and Preliminary Investigation of Bioactive Compounds from Rumex Vesicarius and Terminalia Catappa Plant

2019 ◽  
Vol 8 (3) ◽  
pp. 21-24
Author(s):  
Anandika Suryavanshi ◽  
Anand Murari Saxena
Keyword(s):  
Medicinal Plants ◽  
Bioactive Compounds ◽  
Metabolic Pathways ◽  
Biological Activities ◽  
Preliminary Investigation ◽  
Terminalia Catappa ◽  
Long Time ◽  
Soxhlet Method ◽  
Phytochemical Compounds

The present study was carried out for the determination of bioactive compounds from different extracts of Terminalia catappa and Rumex vesicarius. The plants are mines of several bioactive compounds also called as phytochemical compounds. These bioactive compounds are responsible for imparting such a potential medicinal property in the plants. The medicinal plant contains various types of bioactive compounds including phenols, alkaloids, terpenoids, tannins, glycosides, flavonoids etc. These bioactive compounds take part in various metabolic pathways and impart their effect. Terminalia catappa and Rumex vesicarius are such medicinal plants which are being used for medicinal purposes for long time. Both of them are rich source of potential bioactive compounds and hence carry out several biological activities effective for the treatment of various diseases. Hence the study focuses on determining the types of bioactive compounds they acquire. For this the leaves of T. catappa and dry stems of R. vesicarius were used for the extraction using different solvents with soxhlet method. The extract of different solvents was analyzed for the phytochemical test. The results obtained revealed that the type of solvents is crucial in determining the type of bioactive compounds to be present in extract. The results showed that ethanol and methanol are good solvent choice for extraction for these two plants. The results concludes that the presence of such potential and effective bioactive compounds in their extract makes them important medicinal plants and are hence employed for several researches and also used for treatment of various kinds of diseases.

scholarly journals Analysis of phenolic compounds, antioxidant and antimicrobial properties of some endemic medicinal plants

2018 ◽  
pp. 75-86 ◽  
Author(s):  
Ersan Bektaş ◽  
Kaan Kaltalıoğlu ◽  
Hüseyin Şahin ◽  
Zafer Türkmen ◽  
Ali Kandemir
Keyword(s):  
Phenolic Compounds ◽  
Medicinal Plants ◽  
Antimicrobial Properties

scholarly journals Review of Phytochemicals and Its Biological Activities and Contemporary Nutraceuticals

2019 ◽  
Vol 4 (6) ◽  
pp. 298-310
Author(s):  
Laode Rijai
Keyword(s):  
Secondary Metabolites ◽  
Biological Activities ◽  
Aloe Vera ◽  
Plant Secondary Metabolites ◽  
World Market ◽  
Genetically Engineered ◽  
Pomegranate Juice ◽  
Omega 3 ◽  
Aloe Vera Gel ◽  
High Level

Nutraceutical is food for health with functions of preventive, promotive, rehabilitation, aesthetic, intelligence to curative. Nutraceuticals as food products can have a contemporary value, which is a trend or extraordinary circumstance that attracts consumers because of its function as a supplement, functional food, medical food, and genetically engineered food so that it penetrates the world market without limits. Nutraceuticals that are contemporary make it easy to achieve the goals of health care by using the "nutraceuticals" approach because the client wishes to himself with a high level of confidence in the benefits of the product for health and therefore uses it. Potential compound for nutraceuticals is secondary metabolites because it has multipotential for health, but specific to certain functions. Secondary metabolites, generally sourced from low plants and animals, because these biological groups do not have a perfect secretion system so that metabolites resulting from secondary metabolism are stored in cells and tissues properly, with several functions, among others, for defense and attractiveness of the biological. Some of the classes and compounds of plant secondary metabolites that are known to have potential for nutraceuticals are Terpenoids, Terpenoids non-Carotenoids, Polyphenolics, Phenolic Acids, Non-Flavonoid Polyphenolics, Glucosinolates, Thiosulphinates, Phytosterols, Anthraquinones, Glucosamines, Octacosanolines, Characticines, Chines) Pectin, Pigments, Tocotrienols and Tocopherols, Ubiquinon and -Lipoic Acid. Furthermore, some contemporary nutraceuticals are Spiruline, Broccoli, Aloe Vera Gel and Aloe Juice, Soyfoods, Omega-3- Fatty Acids, Pomegranate Juice, Walnuts, and Organic Mushroom Nutrace.

Sign in / Sign up

Export Citation Format

Share Document