scholarly journals Key indicators and issues of the development of culture and leisure in Moscow

2021 ◽  
Vol 7 (Extra-D) ◽  
pp. 506-516
Author(s):  
Alexey Nikolaevich Boyko ◽  
Elena Evgenevna Kabanova ◽  
Tatiana Anatolyevna Evstratova ◽  
Elena Vladimirovna Litvinova ◽  
Veronika Andreevna Danilova
Keyword(s):  
Human Activity ◽  
Ancient Greece ◽  
Close Relative ◽  
Ancient Rome ◽  
Huge Number ◽  
Object Condition ◽  
Wide Range ◽  
Original Sense ◽  
Almost All ◽  
Key Indicators

The concept of culture exists in almost all languages and is used in a wide range of situations, with a huge number of meanings in different areas of human activity. In its original sense, the word "culture" has never referred to any particular object, condition, or content. The notion of culture first appears in Latin. Poets and scholars of Ancient Rome have used it in their treatises and letters to mean "to cultivate" something or "cultivate" it to improve it. In ancient Greece, a close relative of the term culture has been paideia, which refers to "internal culture" or, in other words, the "culture of the soul". In Latin sources, the word first appears in a treatise on agriculture by the Roman statesman and writer Marcus Porcius Cato (234-149 B.C.), whose Latin translation of the title sounds something like this: agroculture. Hence, the word "culture" is originally used as an agronomic term.

Liberty, Manners, and Politeness in Early Eighteenth-Century England

1989 ◽  
Vol 32 (3) ◽  
pp. 583-605 ◽  
Author(s):  
Lawrence E. Klein
Keyword(s):  
Eighteenth Century ◽  
Fifteenth Century ◽  
Middle Ages ◽  
English Language ◽  
Ancient Greece ◽  
Ancient Rome ◽  
Polite Society ◽  
Wide Range ◽  
Aesthetic Standard ◽  
Early Eighteenth Century

In the early eighteenth century, the language of politeness became a major fixture of English discourse. Centring on the term ‘politeness’ and consisting of a vocabulary of key words (such as ‘refinement’, ‘manners’, ‘character’, ‘breeding’, and ‘civility’) and a range of qualifying attributes (‘free’, ‘easy’, ‘natural’, ‘graceful’, and many others), the language was used to make a wide range of objects intelligible. Though the word ‘polite’ had been in the English language from at least the fifteenth century, denoting the state of being polished or neat in quite literal and concrete ways, the term entered on its significant career only in the mid-seventeenth century, when it began to convey the meanings of studied social behaviour of the sort inspired by and associated with princely courts. However, in the late seventeenth and early eighteenth century, ‘politeness’ grew to cover a range of meanings, considerably freed from the initial association with courts. Several broad categories of usage of the term ‘polite’ are indicative: as a behavioural and moral standard for members of an elite (e.g. ‘polite gentlemen’, ‘polite ladies’, ‘polite society’, ‘polite conversation’); as an aesthetic standard for many kinds of human artifacts and products (e.g. ‘polite arts’, ‘polite towns’, ‘polite learning’, ‘polite buildings’); and as a way of generalizing about and characterizing society and culture (‘polite age’, ‘polite nation’, ‘polite people’). In the latter usage, ‘politeness’ was frequently deployed retrospectively as an attribute of classical civilizations. ‘Politeness’ helped recast the renaissance model of history, in which modernity was separated from its true ancestor, the ancient world, by the vast dark gulf of the middle ages: the ‘politest’ nations were ancient Greece and ancient Rome; the ‘politest’ ages, the spells of Hellenic and Roman creativity.

From the history of the development of electronic dictionaries: foreign and domestic experience

2020 ◽  
Vol 11 (1) ◽  
pp. 6-12
Author(s):  
O. Y. Balalaieva ◽  
Keyword(s):  
Human Activity ◽  
Current Level ◽  
Ease Of Use ◽  
Advanced Search ◽  
Wide Range ◽  
Promising Area ◽  
History Of ◽  
Machine Readable ◽  
Everyday Communication ◽  
Educational Professional

The purpose of the article is to study the dynamics of electronic dictionaries development abroad and in Ukraine using methods of analysis of scientific sources, comparison, generalization and systematization. Electronic dictionaries have been found to be a relatively new phenomenon in the lexicographic market, evolving from machine-readable dictionaries, exact copies of paper editions to complex digital lexicographic systems with a powerful arsenal of functions over the decades. The stages of development of autonomous and online dictionaries are described. Electronic dictionaries due to the advanced search capabilities, speed, simplicity, ease of use, accessibility and compactness have gained popularity among a wide range of users. Today they are used in many spheres of human activity – scientific, educational, professional, everyday communication. However, the analysis of the current level of development of Ukrainian electronic resources indicates a shortage of electronic dictionaries both common and terminological vocabulary. The lack of electronic dictionaries is due to a number of objective problems, both practical and theoretical, that is why research in the field of domestic computer lexicography is a promising area of further research.

First Detection of Tobacco Mosaic Virus in Tobacco Fields in Northern Lebanon

2020 ◽  
Vol 20 ◽  
Author(s):  
Rami Obeid ◽  
Elias Wehbe ◽  
Mohamad Rima ◽  
Mohammad Kabara ◽  
Romeo Al Bersaoui ◽  
...  
Keyword(s):  
Tobacco Mosaic Virus ◽  
Mosaic Virus ◽  
Viral Genome ◽  
Virus Genome ◽  
Enzyme Linked Immunosorbent Assay ◽  
Virus Family ◽  
Crop Fields ◽  
Wide Range ◽  
Almost All ◽  
Das Elisa

Background: Tobacco mosaic virus (TMV) is the most known virus in the plant mosaic virus family and is able to infect a wide range of crops, in particularly tobacco, causing a production loss. Objectives: Herein, and for the first time in Lebanon, we investigated the presence of TMV infection in crops by analyzing 88 samples of tobacco, tomato, cucumber and pepper collected from different regions in North Lebanon. Methods: Double-antibody sandwich enzyme-linked immunosorbent assay (DAS-ELISA), revealed a potential TMV infection of four tobacco samples out of 88 crops samples collected. However, no tomato, cucumber and pepper samples were infected. The TMV+ tobacco samples were then extensively analyzed by RT-PCR to detect viral RNA using different primers covering all the viral genome. Results and Discussion: PCR results confirmed those of DAS-ELISA showing TMV infection of four tobacco samples collected from three crop fields of North Lebanon. In only one of four TMV+ samples, we were able to amplify almost all the regions of viral genome, suggesting possible mutations in the virus genome or an infection with a new, not yet identified, TMV strain. Conclusion: Our study is the first in Lebanon revealing TMV infection in crop fields, and highlighting the danger that may affect the future of agriculture.

INFLUENCE OF WEATHER ON TEMPORARY AND PERMANENT MIGRATION IN RURAL INDIA

2013 ◽  
Vol 04 (02) ◽  
pp. 1350007 ◽  
Author(s):  
K. S. KAVI KUMAR ◽  
BRINDA VISWANATHAN
Keyword(s):  
National Sample ◽  
Sample Survey ◽  
Urban Migration ◽  
Temporary Migration ◽  
Urban Migrants ◽  
Wide Range ◽  
Permanent Migration ◽  
Sample Survey Data ◽  
Almost All ◽  
Temporary Migrants

While a wide range of factors influence rural–rural and rural–urban migration in developing countries, there is significant interest in analyzing the role of agricultural distress and growing inter-regional differences in fueling such movement. This strand of research acquires importance in the context of climate change adaptation. In the Indian context, this analysis gets further complicated due to the significant presence of temporary migration. This paper analyzes how weather and its variability affects both temporary and permanent migration in India using National Sample Survey data for the year 2007–2008. The paper finds that almost all of the rural–urban migrants are permanent. Only temperature plays a role in permanent migration. In contrast, many temporary migrants are rural–rural and both temperature and rainfall explain temporary migration.

scholarly journals Isolation and Characterization of Bacteriophage ZCSE6 against Salmonella spp.: Phage Application in Milk

Biologics ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 164-176
Author(s):  
Abdallah S. Abdelsattar ◽  
Anan Safwat ◽  
Rana Nofal ◽  
Amera Elsayed ◽  
Salsabil Makky ◽  
...  
Keyword(s):  
Pathogenic Bacteria ◽  
Raw Milk ◽  
Salmonella Spp ◽  
Isolation And Characterization ◽  
Food Borne ◽  
Wide Range ◽  
Almost All ◽  
And Control ◽  
Milk And Dairy Products

Food safety is very important in the food industry as most pathogenic bacteria can cause food-borne diseases and negatively affect public health. In the milk industry, contamination with Salmonella has always been a challenge, but the risks have dramatically increased as almost all bacteria now show resistance to a wide range of commercial antibiotics. This study aimed to isolate a bacteriophage to be used as a bactericidal agent against Salmonella in milk and dairy products. Here, phage ZCSE6 has been isolated from raw milk sample sand molecularly and chemically characterized. At different multiplicities of infection (MOIs) of 0.1, 0.01, and 0.001, the phage–Salmonella interaction was studied for 6 h at 37 °C and 24 h at 8 °C. In addition, ZCSE6 was tested against Salmonella contamination in milk to examine its lytic activity for 3 h at 37 °C. The results showed that ZCSE6 has a small genome size (<48.5 kbp) and belongs to the Siphovirus family. Phage ZCSE6 revealed a high thermal and pH stability at various conditions that mimic milk manufacturing and supply chain conditions. It also demonstrated a significant reduction in Salmonella concentration in media at various MOIs, with higher bacterial eradication at higher MOI. Moreover, it significantly reduced Salmonella growth (MOI 1) in milk, manifesting a 1000-fold decrease in bacteria concentration following 3 h incubation at 37 °C. The results highlighted the strong ability of ZCSE6 to kill Salmonella and control its growth in milk. Thus, ZCSE6 is recommended as a biocontrol agent in milk to limit bacterial growth and increase the milk shelf-life.

Soul of Classicality in Western Architectural Design

2014 ◽  
Vol 638-640 ◽  
pp. 2253-2256
Author(s):  
Cong Ru Liu ◽  
Ming Sen Lin ◽  
Qing Li
Keyword(s):  
Significant Role ◽  
Architectural Design ◽  
Ancient Greece ◽  
Architecture Design ◽  
Ancient Rome ◽  
The Past ◽  
Renaissance Period

The classicality of the western architecture establishes its foundation at the beginning of the ancient Greece, is flourished in the ancient Rome and revitalized in the renaissance period, extends to the classicism and the classical revival, and finally is overthrown by the postmodernism. By going through development and prosperity in the past thousands of years, the classical spirit has always played a greatly significant role in the field of western architecture design.

Human RecQ helicases in transcription-associated stress management: bridging the gap between DNA and RNA metabolism

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Tulika Das ◽  
Surasree Pal ◽  
Agneyo Ganguly
Keyword(s):  
Genome Integrity ◽  
Complex Structures ◽  
Huge Number ◽  
Dna Helicases ◽  
Dna Structures ◽  
Recq Helicases ◽  
Dna And Rna ◽  
Cellular Dna ◽  
Almost All ◽  
Transcription And Replication

Abstract RecQ helicases are a highly conserved class of DNA helicases that play crucial role in almost all DNA metabolic processes including replication, repair and recombination. They are able to unwind a wide variety of complex intermediate DNA structures that may result from cellular DNA transactions and hence assist in maintaining genome integrity. Interestingly, a huge number of recent reports suggest that many of the RecQ family helicases are directly or indirectly involved in regulating transcription and gene expression. On one hand, they can remove complex structures like R-loops, G-quadruplexes or RNA:DNA hybrids formed at the intersection of transcription and replication. On the other hand, emerging evidence suggests that they can also regulate transcription by directly interacting with RNA polymerase or recruiting other protein factors that may regulate transcription. This review summarizes the up to date knowledge on the involvement of three human RecQ family proteins BLM, WRN and RECQL5 in transcription regulation and management of transcription associated stress.

Actual Challenges, Risks and Security Safety

2020 ◽  
Vol 1 (1) ◽  
pp. 65-83
Author(s):  
Božidar Forca ◽  
Dragoljub Sekulović ◽  
Igor Vukonjanski
Keyword(s):  
National Security ◽  
Modern World ◽  
Security Strategy ◽  
Theoretical Understanding ◽  
National Security Strategy ◽  
Security Challenges ◽  
Wide Range ◽  
The Subject ◽  
Almost All ◽  
The Relationship

Security is one of the most common terms in the modern world. This statement is supported by the fact that the term security is used in a wide range of areas. The subject of this paper is national security and the challenges, risks and threats to that security in contemporary international relations. The purpose of the work is twofold. First, to show the diversity of theoretical understanding of the term challenge, risk and threat by various authors. On the other hand, the overriding goal is to analyze the relationship to the challenges, risks and threats in different countries. When it comes to national security, challenges, risks and threats, most often, are identified in a document called the national security strategy. This document, as one of the highest in the hierarchy of political acts of every state, when it comes to security, is passed by almost all modern states of the world. The analysis of numerous national security strategies has revealed that it is possible to identify: 1) the challenges, risks and threats that appear in all strategies, 2) the challenges, risks and threats of security that appear in most strategies, and 3) the challenges, risks and threats of security which are country specific.

What Kind of Friction Model Is Needed to Predict Brake Squeal?

2012 ◽  
Author(s):  
Tore Butlin ◽  
Jim Woodhouse
Keyword(s):  
Large Scale ◽  
Dynamic Properties ◽  
Theoretical Work ◽  
Friction Model ◽  
Coupled Systems ◽  
Brake Squeal ◽  
Model Framework ◽  
Wide Range ◽  
Pin On Disc ◽  
Almost All

Predictive models of friction-induced vibration have proved elusive despite decades of research. There are many mechanisms that can cause brake squeal; friction coupled systems can be highly sensitive to small perturbations; and the dynamic properties of friction at the contact zone seem to be poorly understood. This paper describes experimental and theoretical work aimed at identifying the key ingredients of a predictive model. A large-scale experiment was carried out to identify squeal initiations using a pin-on-disc test rig: approximately 30,000 squeal initiations were recorded, covering a very wide range of frequencies. The theoretical model allows for completely general linear systems coupled at a single sliding point by friction: squeal is predicted using a linearised stability analysis. Results will be presented that show that almost all observed squeal events can be predicted within this model framework, but that some subsets require innovative friction modelling: predictions are highly dependent on the particular choice of friction model and its associated parameters.

scholarly journals Two Populations of Glucocorticoid Receptor-Binding Sites in the Male Rat Hippocampal Genome

Endocrinology ◽  
2013 ◽  
Vol 154 (5) ◽  
pp. 1832-1844 ◽  
Author(s):  
J. Annelies E. Polman ◽  
E. Ronald de Kloet ◽  
Nicole A. Datson
Keyword(s):  
Receptor Binding ◽  
Binding Sites ◽  
Glucocorticoid Receptors ◽  
Full Range ◽  
Male Rat ◽  
Motif Analysis ◽  
Wide Range ◽  
Neuronal Processes ◽  
Almost All

Abstract In the present study, genomic binding sites of glucocorticoid receptors (GR) were identified in vivo in the rat hippocampus applying chromatin immunoprecipitation followed by next-generation sequencing. We identified 2470 significant GR-binding sites (GBS) and were able to confirm GR binding to a random selection of these GBS covering a wide range of P values. Analysis of the genomic distribution of the significant GBS revealed a high prevalence of intragenic GBS. Gene ontology clusters involved in neuronal plasticity and other essential neuronal processes were overrepresented among the genes harboring a GBS or located in the vicinity of a GBS. Male adrenalectomized rats were challenged with increasing doses of the GR agonist corticosterone (CORT) ranging from 3 to 3000 μg/kg, resulting in clear differences in the GR-binding profile to individual GBS. Two groups of GBS could be distinguished: a low-CORT group that displayed GR binding across the full range of CORT concentrations, and a second high-CORT group that displayed significant GR binding only after administering the highest concentration of CORT. All validated GBS, in both the low-CORT and high-CORT groups, displayed mineralocorticoid receptor binding, which remained relatively constant from 30 μg/kg CORT upward. Motif analysis revealed that almost all GBS contained a glucocorticoid response element resembling the consensus motif in literature. In addition, motifs corresponding with new potential GR-interacting proteins were identified, such as zinc finger and BTB domain containing 3 (Zbtb3) and CUP (CG11181 gene product from transcript CG11181-RB), which may be involved in GR-dependent transactivation and transrepression, respectively. In conclusion, our results highlight the existence of 2 populations of GBS in the rat hippocampal genome.

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