scholarly journals The Smoking Patterns of Women in Their Forties: Their Relationship to Later Osteoporosis

2012 ◽  
Vol 110 (2) ◽  
pp. 351-362 ◽  
Author(s):  
Judith S. Brook ◽  
Elinor B. Balka ◽  
Chenshu Zhang
Keyword(s):  
Public Health ◽  
Logistic Regression ◽  
Tobacco Use ◽  
Trajectory Analysis ◽  
Osteoporotic Fractures ◽  
Regression Analyses ◽  
Women Smokers ◽  
Smoking Patterns ◽  
Heavy Smokers

Osteoporosis is prevalent among women 50 years of age and older and accounts for numerous fractures and the related deaths of many sufferers. In this study, 22.4% of the women reported having osteoporosis. Smoking contributes substantially to osteoporotic fractures. This study assessed how different trajectories of women's smoking, covering the ages 40 to 48 years, relate to osteoporosis at age 65. Trajectory analysis of tobacco use data reveals smoking patterns which may have differing relationships to osteoporosis. Logistic regression analyses revealed the varying relationships of different smoking patterns to osteoporosis. As hypothesized, the chronic/heavy smokers were significantly more likely than the non-smokers to report having osteoporosis. Quitters and moderate smokers did not differ significantly from non-smokers on the osteoporosis measure. Chronic/heavy smokers should not be the only focus of public health efforts to reduce smoking and the associated risks of osteoporosis. The findings also highlight the efficacy of women smokers quitting in their 40s in order to reduce their likelihood of contracting osteoporosis.

scholarly journals Risk factors for symptomatic Avascular Necrosis (AVN) in a multi-ethnic Systemic Lupus Erythematosus (SLE) cohort

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248845
Author(s):  
Syahrul Sazliyana Shaharir ◽  
Siew Huoy Chua ◽  
Rozita Mohd ◽  
Ruslinda Mustafar ◽  
Malehah Mohd Noh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Avascular Necrosis ◽  
Lupus Erythematosus ◽  
Osteoporotic Fractures ◽  
Protective Effects ◽  
Regression Analyses ◽  
Mobility Limitations ◽  
Factors Associated ◽  
Multivariable Logistic Regression

Avascular necrosis of bone (AVN) is increasingly being recognized as a complication of SLE and causes significant disability due to pain and mobility limitations. We studied the prevalence and factors associated with avascular necrosis (AVN) in a multiethnic SLE cohort. SLE patients who visited the outpatient clinic from October 2017 to April 2019 were considered eligible. Their medical records were reviewed to identify patients who developed symptomatic AVN, as confirmed by either magnetic resonance imaging or plain radiography. Subsequently, their SLE disease characteristics and treatment were compared with the characteristics of patients who did not have AVN. Multivariable logistic regression analyses were performed to determine the independent factors associated with AVN among the multiethnic SLE cohort. A total of 390 patients were recruited, and the majority of them were females (92.6%); the patients were predominantly of Malay ethnicity (59.5%), followed by Chinese (35.9%) and Indian (4.6%). The prevalence of symptomatic AVN was 14.1%, and the mean age of AVN diagnosis was 37.6 ± 14.4 years. Both univariate and multivariable logistic regression analyses revealed that a longer disease duration, high LDL-C (low density lipoprotein cholesterol), positive anti-cardiolipin (aCL) IgG and anti-dsDNA results, a history of an oral prednisolone dose of more than 30 mg daily for at least 4 weeks and osteoporotic fractures were significantly associated with AVN. On the other hand, hydroxychloroquin (HCQ), mycophenolate mofetil (MMF) and bisphosphonate use were associated with a lower risk of AVN. No associations with ethnicity were found. In conclusion, several modifiable risk factors were found to be associated with AVN, and these factors may be used to identify patients who are at high risk of developing such complications. The potential protective effects of HCQ, MMF and bisphosphonates warrant additional studies.

scholarly journals Adolescent Light Cigarette Smoking Patterns and Adult Cigarette Smoking

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
R. Constance Wiener ◽  
Alcinda K. Trickett Shockey ◽  
Susan K. Morgan
Keyword(s):  
Cigarette Smoking ◽  
Healthcare Providers ◽  
Regression Analyses ◽  
Heavy Smoking ◽  
National Longitudinal Study ◽  
Light Smoking ◽  
Smoking Patterns ◽  
The Relationship ◽  
Practical Implications ◽  
Heavy Smokers

Purpose. Light cigarette smoking has had limited research. The purpose of this study was to examine the relationship between light smoking in adolescence with smoking in adulthood. Methods. National Longitudinal Study of Adolescent Health data, Waves I and IV, were analyzed. Previous month adolescent smoking of 1–5 cigarettes/day (cpd) (light smoking); 6–16 cpd (average smoking); 17 or more cpd (heavy smoking); and nonsmoking were compared with the outcome of adult smoking. Results. At baseline, 15.9% of adolescents were light smokers, 6.8% were average smokers, and 3.6% were heavy smokers. The smoking patterns were significantly related to adult smoking. In logistic regression analyses, adolescent light smokers had an adjusted odds ratio (AOR) of 2.45 (95% CI: 2.00, 3.00) of adult smoking; adolescent average or heavy smokers had AOR of 5.57 (95% CI: 4.17, 7.43) and 5.23 (95% CI: 3.29, 8.31), respectively. Conclusion. Individuals who initiate light cigarette smoking during adolescence are more likely to smoke as young adults. Practical Implications. When screening for tobacco use by adolescents, there is a need to verify that the adolescents understand that light smoking constitutes smoking. There is a need for healthcare providers to initiate interventions for adolescent light smoking.

scholarly journals Association of anemia and COVID-19 in hospitalized patients

2021 ◽  
Author(s):  
Chong Chen ◽  
Wenhui Zhou ◽  
Wenliang Fan ◽  
Xianying Ning ◽  
Shuai Yang ◽  
...  
Keyword(s):  
Public Health ◽  
Logistic Regression ◽  
Clinical Characteristics ◽  
Early Stage ◽  
Laboratory Data ◽  
Severe Pneumonia ◽  
Regression Analyses ◽  
Major Threat ◽  
Close Relationship ◽  
Union Hospital

Aim: COVID-19 is a major threat to public health worldwide. A large proportion of COVID-19 patients is proved to develop anemia. Herein, we investigate the association between anemia and severe pneumonia. Materials & methods: 137 of COVID-19-confirmed patients admitted to Wuhan Union Hospital (Wuhan, China) from 13 February to 17 March 2020 were included. Their clinical characteristics and laboratory data were studied, and multivariable logistic regression analyses were performed. Results: The anemic patients were less likely to develop fever in the early stage of COVID-19. Elevated IL-6 levels were found in anemic COVID-19 patients compared with those without anemia. COVID-19 patients with anemia had an 8.2 times greater possibility of developing severe pneumonia compared with their counterparts without anemia. Conclusion: This study comprehensively describes the clinical characteristics of anemic patients with ordinary, severe and critical COVID-19 and demonstrates the close relationship between the anemia and severe COVID-19.

scholarly journals 0241 Habitual Daytime Sleepiness and the Timing of Use of Alcohol, Tobacco, and Caffeine

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A92-A93
Author(s):  
A Tubbs ◽  
L Hale ◽  
C Branas ◽  
W D Killgore ◽  
C C Wills ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Tobacco Use ◽  
Real World ◽  
Daytime Sleepiness ◽  
Regression Analyses ◽  
Drinking Alcohol ◽  
Use Patterns ◽  
Healthy Activity ◽  
The Impact ◽  
The Relationship

Abstract Introduction Alcohol, caffeine, and tobacco are frequently used in the community, and the timing of use may impact daytime sleepiness. The present analysis examined relationships between daytime sleepiness and timing of alcohol, tobacco, and caffeine use in a real-world sample. Methods Data were from the Sleep and Healthy Activity, Diet, Environment, and Socialization (SHADES) study of N=1007 adults age 22–60 from the community. Daytime sleepiness was assessed with the Epworth Sleepiness Scale (ESS). Participants were asked if they had ever used caffeine, alcohol and tobacco. If they reported using a substance, they were then asked which times of day they were likely to use the substance: 5AM-8AM, 8AM-11AM, 11AM-2PM, 2PM-5PM, 5PM-8PM, 8PM-11PM, 11PM-2AM, and 2AM-5AM. Logistic regression analyses examined the relationship between ESS score and likelihood of use of substances at each time. Results ESS score was associated with increased odds of ever using alcohol (OR: 1.05, 95% CI: 1.01 to 1.09) or tobacco (OR: 1.04, 95% CI: 1.01 to 1.07). ESS score was associated with an increased likelihood of drinking alcohol in the morning (5AM-8AM, OR: 1.13) and night (11PM-5AM, OR: 1.05). Sleepiness was also associated with increased likelihood of tobacco use in the afternoon (11AM-2PM, OR 1.04) and night (11PM-2AM, OR 1.05). Finally, ESS score was associated with increased likelihood of caffeine use during the midday and afternoon (11AM-5PM, OR: 1.04). Conclusion Greater sleepiness is associated with use of alcohol in the morning and at night, and with use of tobacco in the afternoon and at night. Finally, increased sleepiness was associated with caffeine use during the latter part of the workday. Some of these use patterns may be a cause of sleepiness (e.g., morning alcohol use or nighttime smoking) and some a consequence (e.g., daytime caffeine and tobacco use). More research on the impact of real-world sleepiness on real-world substance use is warranted. Support This work was supported by a grant from Jazz Pharmaceuticals Dr. Grandner is supported by R01MD011600The SHADES study was funded by R21ES022931

Perceived Effectiveness of Random Testing for Alcohol and Drugs in the Australian Aviation Community

2012 ◽  
Vol 2 (2) ◽  
pp. 72-81
Author(s):  
Christina M. Rudin-Brown ◽  
Eve Mitsopoulos-Rubens ◽  
Michael G. Lenné
Keyword(s):  
Logistic Regression ◽  
Online Survey ◽  
Random Testing ◽  
Regression Analyses ◽  
Perceived Effectiveness ◽  
Student Pilots ◽  
Alcohol And Drugs ◽  
Positive Attitudes ◽  
One Year ◽  
Alcohol And Other Drugs

Random testing for alcohol and other drugs (AODs) in individuals who perform safety-sensitive activities as part of their aviation role was introduced in Australia in April 2009. One year later, an online survey (N = 2,226) was conducted to investigate attitudes, behaviors, and knowledge regarding random testing and to gauge perceptions regarding its effectiveness. Private, recreational, and student pilots were less likely than industry personnel to report being aware of the requirement (86.5% versus 97.1%), to have undergone testing (76.5% versus 96.1%), and to know of others who had undergone testing (39.9% versus 84.3%), and they had more positive attitudes toward random testing than industry personnel. However, logistic regression analyses indicated that random testing is more effective at deterring AOD use among industry personnel.

Epidemiology of pediatric hydrocephalus in Haiti: analysis of a surgical case series

2019 ◽  
Vol 23 (5) ◽  
pp. 568-576
Author(s):  
Michael Ragheb ◽  
Ashish H. Shah ◽  
Sarah Jernigan ◽  
Tulay Koru-Sengul ◽  
John Ragheb
Keyword(s):  
Public Health ◽  
Logistic Regression ◽  
Head Circumference ◽  
Rainy Season ◽  
Statistical Tests ◽  
Multivariate Logistic Regression Analysis ◽  
Case Series ◽  
Multivariate Logistic Regression ◽  
Surgical Case ◽  
Operative Notes

OBJECTIVEHydrocephalus is recognized as a common disabling pediatric disease afflicting infants and children disproportionately in the developing world, where access to neurosurgical care is limited and risk of perinatal infection is high. This surgical case series describes the Project Medishare Hydrocephalus Specialty Surgery (PMHSS) program experience treating hydrocephalus in Haiti between 2008 and 2015.METHODSThe authors conducted a retrospective review of all cases involving children treated for hydrocephalus within the PMHSS program in Port-au-Prince, Haiti, from 2008 through 2015. All relevant epidemiological information of children treated were prospectively collected including relevant demographics, birth history, hydrocephalus etiology, head circumference, and operative notes. All appropriate associations and statistical tests were performed using univariate and multivariate logistic regression analyses.RESULTSAmong the 401 children treated within PMHSS, postinfectious hydrocephalus (PIH) accounted for 39.4% (n = 158) of cases based on clinical, radiographic, and endoscopic findings. The majority of children with hydrocephalus in Haiti were male (54.8%, n = 197), born in the rainy season (59.7%, n = 233), and born in a coastal/inland location (43.3%, n = 61). The most common surgical intervention was endoscopic third ventriculostomy with choroid plexus cauterization (ETV/CPC) (45.7%, n = 175). Multivariate logistic regression analysis yielded coastal birth location (OR 3.76, 95% CI 1.16–12.18) as a statistically significant predictor of PIH. Increasing head circumference (adjusted OR 1.06, 95% CI 0.99–1.13) demonstrated a slight trend toward significance with the incidence of PIH.CONCLUSIONSThis information will provide the foundation for future clinical and public health studies to better understand hydrocephalus in Haiti. The 39.4% prevalence of PIH falls within observed rates in Africa as does the apparently higher prevalence for those born during the rainy season. Although PIH was the most frequent etiology seen in almost all birth locations, the potential relationship with geography noted in this series will be the focus of further research in an effort to understand the link between climate and PIH in Haiti. The ultimate goal will be to develop an appropriate public health strategy to reduce the burden of PIH on the children of Haiti.

PELAYANAN PUBLIK KESEHATAN PUSKESMAS DALAM MEMBERIKAN KEPUASAN MASYARAKAT DI KABUPATEN SUMENEP

2018 ◽  
Vol 3 (3) ◽  
Author(s):  
Aryo Wibisono ◽  
R. Amilia Destryana
Keyword(s):  
Public Health ◽  
Logistic Regression ◽  
Patient Satisfaction ◽  
Health Center ◽  
Public Service ◽  
Public Health Center ◽  
The Public ◽  
Regression Methods ◽  
Total Satisfaction ◽  
The Relationship

This study aims to determine the index of public satisfaction in public health center services in Sumenep Regency and the relationship between the services to the public satisfaction. The analysis measured the index of public satisfaction and logistic regression methods to determine the effect of the relationship on total satisfaction in the health services of Public Health Center. The results of the study are the alignment between interests and patient satisfaction is still not aligned, there are still differences between interests and satisfaction, the pattern of the result is the relationship between the assurance dimension to the service satisfaction of the public health center, and the results of the index of public satisfaction  values show that the results of the community assess the public health center performance is very good by getting an A grade. Keywords: public service, logistic regretion, index of public satisfaction

Tobacco as a Matter of Public Health: Ethical Issues

2019 ◽  
pp. 494-510
Author(s):  
Kristin Voigt
Keyword(s):  
Public Health ◽  
Tobacco Use ◽  
Ethical Issues ◽  
Population Level ◽  
Third Parties ◽  
Background Factors ◽  
Normative Issues

This chapter considers normative issues that tobacco raises at the population level, particularly with respect to the anti-smoking strategies policymakers might pursue and the reasons and justifications underlying these strategies. After setting out several background factors that shape the debate, the chapter discusses different grounds on which state and public health actors might seek to restrict tobacco use, considering in turn those justifications that focus on protecting smokers and those that seek to protect third parties. The chapter then considers normative problems arising in relation to specific anti-smoking strategies, such as restrictions on the sale, use, and marketing of cigarettes; taxation; incentives for cessation; and denormalization strategies. Issues of paternalism and the stigma associated with smoking are also discussed.

scholarly journals Impact of digitally acquired peer diagnostic input on diagnostic confidence in outpatient cases: A pragmatic randomized trial

2020 ◽  
Author(s):  
Elaine C Khoong ◽  
Valy Fontil ◽  
Natalie A Rivadeneira ◽  
Mekhala Hoskote ◽  
Shantanu Nundy ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Randomized Trial ◽  
Odds Ratio ◽  
Primary Outcome ◽  
Mixed Effects ◽  
Regression Analyses ◽  
Diagnostic Confidence ◽  
Diagnostic Uncertainty ◽  
Intervention Impact ◽  
High Uncertainty

Abstract Objective The study sought to evaluate if peer input on outpatient cases impacted diagnostic confidence. Materials and Methods This randomized trial of a peer input intervention occurred among 28 clinicians with case-level randomization. Encounters with diagnostic uncertainty were entered onto a digital platform to collect input from ≥5 clinicians. The primary outcome was diagnostic confidence. We used mixed-effects logistic regression analyses to assess for intervention impact on diagnostic confidence. Results Among the 509 cases (255 control; 254 intervention), the intervention did not impact confidence (odds ratio [OR], 1.46; 95% confidence interval [CI], 0.999-2.12), but after adjusting for clinician and case traits, the intervention was associated with higher confidence (OR, 1.53; 95% CI, 1.01-2.32). The intervention impact was greater in cases with high uncertainty (OR, 3.23; 95% CI, 1.09- 9.52). Conclusions Peer input increased diagnostic confidence primarily in high-uncertainty cases, consistent with findings that clinicians desire input primarily in cases with continued uncertainty.

785 Reported Restful Sleep Predicting Emotional Distress: Does Exercise (and its modalities) moderate?

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A305-A306
Author(s):  
Jesse Moore ◽  
Ellita Williams ◽  
Collin Popp ◽  
Anthony Briggs ◽  
Judite Blanc ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Aerobic Exercise ◽  
Regression Models ◽  
Regression Analyses ◽  
Logistic Regression Models ◽  
The Past ◽  
Strengthening Exercise ◽  
Waking Up ◽  
The Relationship ◽  
Age And Sex

Abstract Introduction Literature shows that exercise moderates the relationship between sleep and emotional distress (ED.) However, it is unclear whether different types of exercise, such as aerobic and strengthening, affect this relationship differently. We investigated the moderating role of two types of exercise (aerobic and strengthening) regarding the relationship between ED and sleep. Methods Our analysis was based on data from 2018 National Health Interview Survey (NHIS), a nationally representative study in which 2,814 participants provided all data. Participants were asked 1) “how many days they woke up feeling rested over the past week”, 2) the Kessler 6 scale to determine ED (a score >13 indicates ED), and 3) the average frequency of strengthening or aerobic exercise per week. Logistic regression analyses were performed to determine if the reported days of waking up rested predicted level of ED. We then investigated whether strengthening or aerobic exercise differentially moderated this relationship. Covariates such as age and sex were adjusted in the logistic regression models. Logistic regression analyses were performed to determine if subjective reporting of restful sleep predicted level of ED. We investigated whether strengthening exercise or aerobic exercise differentially moderated this relationship. Covariates such as age and sex were adjusted in the logistic regression models. Results On average, participants reported 4.41 restful nights of sleep (SD =2.41), 3.43 strengthening activities (SD = 3.19,) and 8.47 aerobic activities a week (SD=5.91.) We found a significant association between days over the past week reporting waking up feeling rested and ED outcome according to K6, Χ2(1) = -741, p= <.001. The odds ratio signified a decrease of 52% in ED scores for each unit of restful sleep (OR = .48, (95% CI = .33, .65) p=<.001.) In the logistic regression model with moderation, aerobic exercise had a significant moderation effect, Χ2(1) = .03, p=.04, but strengthening exercise did not. Conclusion We found that restful sleep predicted reduction in ED scores. Aerobic exercise moderated this relationship, while strengthening exercise did not. Further research should investigate the longitudinal effects of exercise type on the relationship between restful sleep and ED. Support (if any) NIH (K07AG052685, R01MD007716, K01HL135452, R01HL152453)

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