scholarly journals Joinpoint Regression Analysis of Potential Years of Life Lost Due to Main Causes of Death in Poland, Years 2002–2011

2013 ◽  
Vol 35 (1) ◽  
pp. 157-167
Author(s):  
Michalina Krzyżak ◽  
Dominik Maślach ◽  
Martyna Skrodzka ◽  
Katarzyna Florczyk ◽  
Anna Szpak ◽  
...  

Abstract The purpose of the study was to analyse the level and the trends of Potential Years of Life Lost due to the main causes of death in Poland in the years 2002-2011. The material for the study was the information from the Central Statistical Office on the number of deaths due to the main causes of death in Poland in the years 2002-2011. The premature mortality analysis was conducted with the use of the PYLL (Potential Years of Life Lost) indicator. PYLL rate was calculated following the method proposed by J. Romeder, according to which premature mortality was defined as death before the age of 70. Time trends of PYLL rate and the average annual percent change (APC - Annual Percent Change) were assessed using jointpoint models and the Joinpoint Regression Program. In the years 2002-2011, PYLL rate for all-cause deaths decreased by 7.0% among men and 8.1% among women. In 2011, the main reasons for PYLL among men were: external causes (27.6%), cardiovascular diseases (24.2%) and cancers (20.3%). Among women the leading causes were: cancers (41.1%), cardiovascular diseases (19.7%) and external causes (12.5%). PYLL rate increased among men for colorectal cancer, and among women for colorectal and lung cancer. The presented epidemiological situation for premature mortality in Poland shows that in the majority of cases it is caused by preventable deaths, which highlights a need to intensify measures in primary and secondary prevention.

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
S Sauliune ◽  
O Mesceriakova-Veliuliene ◽  
R Kalediene

Abstract Introduction Health inequalities have emerged as a big issue of public health in Lithuania. Recent studies have demonstrated increasing mortality differentials between marital status groups, occurring mainly due to a decline in mortality of the married populations. The aim of the study - to determine changes in inequalities in mortality from major causes of death by marital status in Lithuania during 2001-2014. Methods Individual records from population censuses conducted in 2001 and 2011, National Mortality Register (period of 2001-2014), and Population Register (period of 2001-2014) have been linked using personal identification number. Study included those aged 30+. Mortality rates from cardiovascular diseases, cancer, external causes and digestion system diseases by the marital status (married and unmarried - never married, the widowed and the divorced) were calculated per 100 000 person years and standardized by age. Inequalities in mortality were assessed calculating rate ratio, while trends in it - conducting the Joinpoint regression analysis. Results Mortality from all analyzed causes of death among males and females in 2001 and 2014 was statistically significantly higher in unmarried compared to married. Inequalities in mortality by marital status increased statistically significantly in Lithuania throughout the period of 2001-2014 from cardiovascular diseases, cancer and external causes. The most significant increase in inequalities by 3.3% (p < 0.05) on average per year was estimated from external causes among males. Inequalities in mortality from digestion system diseases did not change significantly throughout the study period. Conclusions Inequalities in mortality by marital status increased significantly in Lithuania throughout the period of 2001-2014 with the most significant increase from external causes. Key messages Mortality from all analyzed causes of death among Lithuanian males and females in 2001 and 2014 was statistically significantly higher in unmarried compared to married. Inequalities in mortality by marital status increased significantly in Lithuania throughout the period of 2001-2014 with the most significant increase from external causes.


Author(s):  
U. Fedeli ◽  
E. Schievano ◽  
S. Masotto ◽  
E. Bonora ◽  
G. Zoppini

Abstract Purpose Diabetes is a growing health problem. The aim of this study was to capture time trends in mortality associated with diabetes. Methods The mortality database of the Veneto region (Italy) includes both the underlying causes of death, and all the diseases mentioned in the death certificate. The annual percent change (APC) in age-standardized rates from 2008 to 2017 was computed by the Joinpoint Regression Program. Results Overall 453,972 deaths (56,074 with mention of diabetes) were observed among subjects aged ≥ 40 years. Mortality rates declined for diabetes as the underlying cause of death and from diabetes-related circulatory diseases. The latter declined especially in females − 4.4 (CI 95% − 5.3/− 3.4), while in males the APC was − 2.8 (CI 95% − 4.0/− 1.6). Conclusion We observed a significant reduction in mortality during the period 2008–2017 in diabetes either as underlying cause of death or when all mentions of diabetes in the death certificate were considered.


2020 ◽  
Author(s):  
Bogdan Wojtyniak ◽  
Jakub Stokwiszewski

Our study, availing the new, agreed by the OECD and Eurostat, lists of preventable and treatable causes of death, seeks to quantify the contribution of avoidable causes to premature mortality and its dynamics in Poland and Central European countries – Czechia, Hungary, Lithuania and Slovenia, in comparison with Sweden serving as a benchmark country in 1999–2017. We calculated age standardised death rates for the broad groups of avoidable causes and more specific ones, which comprised preventable and treatable cancer and diseases of the circulatory system (DCS), preventable injuries and alcohol-related diseases. Deaths from not avoidable causes were also analysed. The analysis of time trends in the death rates and calculation of the Average Annual Percent Change (AAPC) for the overall trend were performed with joint-point models. The contribution of changes in mortality from avoidable causes to increase life expectancy during 1999–2017 and contribution of the difference in mortality from these causes to the difference in life expectancy between five countries and Sweden were based on the decomposition of temporary life expectancy between birth and age 75 [e(0-75)]. For the calculation of life expectancy, we used the classic Chiang method and the decomposition of life expectancy by the death causes and age was conducted with the Arriaga method. The AAPC of death rates from avoidable causes in 1999–2017 was similar in all the countries but Lithuania, where the decline started later. The decline in the death rates from not avoidable causes is much slower than the rates from avoidable causes. Mortality from treatable causes was decreasing faster than from preventable causes in most populations. In 1999–2017, the average rate of mortality decline for preventable cancer was greater among men than among women, while for treatable cancer the sex-related differences were much smaller and in favour of women. As for preventable and treatable death from DCS, their decrease was faster among women than men in all the countries but Sweden. Improvements in mortality from causes that could be avoided through prevention or treatment made substantial positive contributions to the overall change in life expectancy in all the countries. The differences in temporary life expectancy e(0-75) between the analysed Central European countries and Sweden were much smaller in 2017 than in 1999, due to the reduction of the gap in mortality from avoidable causes. Our results show that among men, and to a lesser extent among women, mortality from preventable causes contributes more than mortality from causes that can be effectively treated to shorter life expectancy in the countries of Central Europe than in Sweden. This indicates that in reducing the health gap between the inhabitants of Central Europe and Western Europe, the healthcare system should consider disease prevention even to a greater extent than just treating them.


2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Alex Rodrigues Moura ◽  
Adriane Dórea Marques ◽  
Mylena Santos Dantas ◽  
Érika de Abreu Costa Brito ◽  
Mariana do Rosário Souza ◽  
...  

Abstract Objectives This study was conducted to analyze the trends in colorectal cancer (CRC) incidence and mortality in the city of Aracaju, Sergipe State, Brazil, between 1996 and 2015 with Joinpoint Regression Program 4.7.0.0 and to identify the geographical distribution of CRC in the municipality. Results A total of 1322 cases of CRC and 467 CRC-related deaths during the study period were included. In total, 40% of the incident cases and 43% of the deaths occurred in men, while 60% of the incident cases and 57% of the deaths occurred in women. Males who were 20 to 44 years old had the most significant trend in growth. Among women, those in the group aged 45 to 64 years had the highest observed annual percent change (APC). In both sexes, mortality was stable. Regarding the geographic distribution, there were constant hotspots in the northeast region of the municipality. This study showed a significant increase in incidence, mainly in young men between 20 and 44 years of age, but stable mortality in Aracaju.


2020 ◽  
Vol 9 (11) ◽  
pp. e3389119799
Author(s):  
Luisa Chrisdayla Macêdo Santos ◽  
Anando Rodrigues de Carvalho ◽  
Maria Bianca Pereira Freitas ◽  
Emanuel Thomaz de Aquino Oliveira ◽  
Fernando Rocha dos Santos ◽  
...  

Introduction: Injuries or any other health problems with sudden onset, generated by violence or other exogenous cause, are called external causes (EC). The indicator Potential Years of Life Lost - PYLL expresses the impact of early deaths in relation to the life expectancy for a given population. ECs were the major causes of death in children aged 1 to 9 years with 1,037 deaths (19.38%). Objective: To determine PYLL by EC among children aged 1 to 9 years in the state of Piauí, Brazil. Methods: This is a retrospective, longitudinal study with a quantitative approach. Its scenario is the State of Piauí. The population and sample were composed of deaths from EC registered in the Mortality Information System - MIS from Brazil, which occurred in children in the intended age group. For data analysis, the method that establishes a limit age for the calculation of PYLL was used, based on the average life of the population. Results: In Piauí between January 2000 and December 2018, there were 1,037 deaths (11.67%). The highest number of PYLL was found among male children, aged 5 to 9 years. Deaths caused by drowning were predominant, with 258 deaths (24.9%), being responsible for 16,857 PYLL, followed by accidents with pedestrians, with 184 deaths (17.8%), adding up to 11,911.5 years. Conclusion: Accidental drowning and submersion and pedestrian accidents predominate as the main EC. It can be estimated that 67,581 years of life for children aged 1 to 9 years were lost by EC in Piauí.


2020 ◽  
Author(s):  
Xin Hu ◽  
Yong Lin ◽  
Lanjing Zhang

AbstractOverall mortality among U.S. adults was stable in the past years, while racial disparity was found in 10 leading causes of death or age-specific mortality in U.S. Blacks or African Americans. However, the trends in sex- and race-adjusted age-standardized cause-specific mortality are poorly understood. This study was aimed at identifying the UCD with sex- and race-adjusted, age-standardized mortality that was changing in recent years. We extracted the data of underlying causes of death (UCD) from the Multiple Cause of Death database of the Centers for Disease Control and Prevention (CDC). Multivariable log-linear regression models were used to estimate trends in sex- and race-adjusted, age-standardized mortality during 2013-2017. A total of 31,029,133 deaths were identified. Among the list of 113 UCD compiled by the CDC, there were 29 UCD with upward trend, 33 UCD with downward trend and 56 UCD with no significant trend. The 2 UCD with largest annual percent change were both nutrition related (annual percent change= 17.73, 95% CI [15.13-20.33] for malnutrition and annual percent change= 17.49, 95% CI [14.94-20.04] for Nutritional deficiencies), followed by Accidental poisoning and exposure to noxious substances. This study thus reported the UCD with changing mortality in recent years, which was sex- and race-adjusted and age-standardized. More efforts and resources should be focused on understanding, prevention and control of the mortality linked to these UCD. Continuous monitoring of mortality trends is recommended.


Medicina ◽  
2013 ◽  
Vol 49 (1) ◽  
pp. 7 ◽  
Author(s):  
Ramunė Kalėdienė ◽  
Skirmantė Sauliūnė

The aim of the study was to analyze trends in overall mortality and mortality from major causes of death, detect differences in cut points, and estimate the contribution of the major causes of death to the changes in overall mortality throughout 2 decades of independence in Lithuania (1991–2000 and 2001–2010). Material and Methods. Overall mortality and mortality from cardiovascular diseases, cancer, and external causes were analyzed for the periods of 1991–2000 and 2001–2010. Joinpoint analysis was used to identify the best-fitting points wherever a statistically significant change in mortality occurred, and analysis of components was applied for the assessment of the contribution of major causes of death. Results. The 1991–1994 period was identified as the most negative in terms of increasing mortality from all major causes of death, while the 2007–2010 period was most favorable, when the most significant decline in overall mortality was observed (4.84% per year for males and 4.41% per year for females). External causes contributed most to the growing overall mortality in 1991–1994 both for males and females (37.20% and 25.29%, respectively). Since 2007, all major causes contributed positively to the declining overall mortality of the Lithuanian population. The most significant contribution was made by cardiovascular diseases and external causes. Conclusions. Despite the considerable transformations of socioeconomic situation and economic crisis, it is likely that Lithuania is entering into the stage of positive health development. For assuring this trend in the future, investments in sustainable health and social developments are inevitable.


2020 ◽  
Author(s):  
Alex Rodrigues Moura ◽  
Adriane Dorea Marques ◽  
Mylena Santos Dantas ◽  
Érika Abreu Costa Brito ◽  
Mariana Rosário Souza ◽  
...  

Abstract Objectives: This study was conducted to analyse the trends in the incidence and mortality of colorectal cancer (CRC) in the city of Aracaju, Sergipe State, Brazil, between 1996 and 2015 through statistical analysis using the Joinpoint Regression Program 4.7.0.0. and to identify its geographical distribution in the municipality. Results: A total of 1,322 cases and 467 deaths of CRC over the study period were included. Men´s incident cases comprised 40% of the sample, and women´s 60%. The death cases were 43% for men and 57% for women. Among the 20 – 44 year age group, for males, there was a highest significant growth trend. For women, the growth trend, with the Annual Percent Change (APC) observed, was the 45 and 64 years age group. Regarding mortality both genders, trends were stable. Regarding geographic distribution, there was a constancy of hotpoints in the northeast region of the municipality. This study showed the increasing in incidence mainly the young men between 20 to 44 years, with significantly statistical, but with mortality stability in Aracaju.


2021 ◽  
Vol 18 (3) ◽  
pp. 27-45
Author(s):  
A. V. Korolenko

The continuation and deepening of regional studies of the nosological and age and gender structure of mortality and its temporal dynamics is due both to the need for scientific monitoring of the implementation of regional programs and projects of the Vologda Oblast dedicated to the protection and promotion of public health, and the need to update the trends in mortality of the region residents in the context of modern socio-demographic challenges (population aging, depopulation, a complex epidemiological situation against the background of the spread of coronavirus infection).The purpose of the study was the analysis of the nosological and age and gender profile of mortality in the Vologda Oblast and the resulting demographic losses, including their transformation over the period from 2015 to 2019. The choice of the analyzed period is not accidental: if in 2015 the region was characterized by the most positive indicators of natural population movement (the total coefficient of natural loss since the beginning of the 2000s reached a minimum of -1.1 per mille), then by 2019 the situation changed dramatically — the indicator of natural loss increased and amounted to - 4.5 per mille.Materials and methods. The study was based on both general scientific and special statistical and demographic methods of research — structural and dynamic analysis of mortality indicators of the Vologda oblast population; assessment of demographic losses due to premature mortality by calculating lost years of potential life; calculation of mortality rates. The information base was the data of the territorial body of the Federal state statistics service for the Vologda Oblast, in particular, the annual data on the distribution of the deceased by sex, age groups and causes of death for 2015-2019.Results. The conducted study allowed us to establish that, in general, the structure of mortality in the region shows signs of its gradual modernization: the level of mortality from diseases of the circulatory system, external causes of death and their share in the total number of deaths are reduced, while increasing the proportion of neoplasms, symptoms, signs, deviations from the norm detected in clinical and laboratory tests, which is quite natural due to the shift in mortality to older age groups. At the same time, its features “slow down” the evolution of the mortality structure, such as a high proportion of young age groups (under 45 years old), especially categories 30-44 years old, in mortality from external causes, infectious and parasitic diseases, endocrine diseases, nutritional disorders, metabolic disorders and, as a result, the large scale of premature mortality of the region's population; male premature super-mortality, as well as the high contribution of the child population (0-14 years old) to premature mortality from diseases of the nervous system and sensory organs.Conclusion. Against the background of the coronavirus pandemic, the fact of a high contribution of young age groups (up to 45 years) to mortality from infectious and parasitic diseases is of great concern due to the likelihood of a sharp increase in the scale of human losses as a result of the layering of new premature deaths due to the consequences of COVID-19. It is considered necessary to include additional indicators of mortality reflecting its gender, age and nosological profile in the regional comprehensive program “Public health — in the center of attention”.


2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
O Meščeriakova-Veliulienė ◽  
R Kalėdienė ◽  
S Sauliūnė ◽  
S Kaselienė

Abstract Background The aim of the study was to evaluate mortality inequalities from major causes of death by education in Lithuania during 2001-2014. Methods Information on deaths (aged 30+) from cardiovascular diseases (ICD-10 codes I00-I99), cancer (ICD-10 codes C00-C97), external causes (ICD-10 codes V01-Y98), and digestive system diseases (ICD-10 codes K00-K93) was obtained from Statistics Lithuania. Mortality rates from these causes were calculated by the level of education (high (post-secondary non-tertiary, tertiary) and low (unknown, preprimary or no education, primary, lower secondary, upper secondary)) per 100,000 person-years. For the assessment of mortality trends during 2001-2014, the Joinpoint regression analysis was applied. Results During the analyzed period, mortality from all major causes was higher in the lower educational group (p < 0.05). The most prominent differences in mortality rates between educational groups were found from external causes and cardiovascular diseases. Mortality from cardiovascular diseases (by 2.22% per year), cancer (by 1.87% per year) and particularly from external causes (by 5.2% per year) declined in higher educational group (p < 0.05). In the lower educational groups mortality declined only from cardiovascular diseases (by 0.73% per year), however mortality increased from cancer (by 0.64% per year) and digestion system diseases (by 5.20% per year) (p < 0.05). Conclusions Mortality from major causes of death in both educational groups changed unevenly during 2001-2014. In higher educational group mortality declined from cardiovascular diseases, cancer, and especially from external causes, while in lower educational group - just from cardiovascular diseases. Key messages In Lithuania, there are still significant inequalities in mortality from the major causes of death by education. Therefore, more attention should be paid for the improvement of the health of the population with lower education.


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