Epidemiological and Clinical Characteristics of Infants with Visceral Leishmaniasis hospitalized in Ardabil city Hospital during 2011-6

Author(s):  
Adel Mirzaei
2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Abdoulaye K. Kone ◽  
Doumbo Safiatou Niaré ◽  
Martine Piarroux ◽  
Arezki Izri ◽  
Pierre Marty ◽  
...  

Visceral leishmaniasis (VL) is the most serious form of human leishmaniasis. VL is understudied in West Africa. The increasing number of patients at-risk, including persons living with HIV and other chronic immunosuppressive diseases, and likely underreporting of VL related to diagnostic challenges advocate for review of existing data to understand VL regional epidemiology. Our review aims to describe the clinical characteristics and epidemiology of Human VL (HVL) in West Africa. We conducted a literature search to identify peer-reviewed articles and grey literature sources using the search terms “Visceral leishmaniasis West Africa”, “Leishmania donovani West Africa”; and “Leishmania infantum West Africa”. Thirty published articles report HVL from seven countries, including The Gambia, Niger, Nigeria, Ivory Coast, Togo, Burkina Faso, and Guinea Bissau. Three countries report cases of Canine Visceral Leishmaniasis (CVL), including The Gambia, Senegal, and Burkina Faso. Niger, Nigeria, and Ivory Coast report the greatest number of HVL cases. As VL is present in West Africa, active surveillance, increased diagnostic capacity, and studies of vectors and reservoirs are essential to better understand VL epidemiology in the region.


2021 ◽  
pp. 563-572
Author(s):  
Ingrid Faustine ◽  
Amarila Malik ◽  
Retnosari Andrajati ◽  
Septelia Inawati Wanandi

Corona virus infection (COVID-19) is still an unsolved problem in Indonesia until this year. Apart from Java, other islands, including Sulawesi, were also badly affected. The very high mortality rate in Central Sulawesi (3.36%) poses a challenge for health workers; therefore, they should be well informed and with up-to-date information about correct therapeutic decisions. One of the most common comorbidities that often occurs with the severity and mortality of COVID-19 is hypertension. This study aims to determine the clinical characteristics and severity profile and their relationship with the mortality rate of COVID-19 patients with hypertension in Palu, Central Sulawesi. A total of 185 data on COVID-19 patients undergoing treatment at the Palu City Hospital during 2021 and meeting the criteria were recruited as research samples. Patients were divided into two categories, hypertensive (43%) and non-hypertensive (57%). The results showed that the age group, comorbid diabetes mellitus, cardiovascular, blood pressure, and blood glucose levels showed a significant relationship between the two groups (p < 0.05). The median length of stay was 12 days, with conditions leading to discharge (83%) and death (17%); patients who died were hospitalized in moderate and severe clinical conditions. Age group, liver function, and kidney function were positively correlated with severity and mortality. However, hypertension did not show a significant relationship with the severity and mortality of COVID-19 patients.


Author(s):  
Ghasem Fattahzadeh-Ardalani ◽  
Afshan Sharghi ◽  
Abolfazl Atalu ◽  
Farzad Noori

Introduction: Stroke is the third most common cause of death in world after heart diseases and cancer. Due to the higher rate of stroke and less attention to its occurrence, assessing the prevalence of ischemic brain stroke and its clinical patterns across countries and nations such as Iran could be valuable and important. Objectives: The aim of this study was to assess the epidemiological, Risk factor and clinical characteristics of ischemic stroke in Ardabil province. Materials and Methods: This descriptive cross-sectional study has been done on 676 patients with ischemic stroke who referred to Ardabil city hospital during at year 2018. Data collected by using a checklist including demographic and clinical data of patients. Collected data were analyzed by statistical methods in SPSS version 21. The p-value less than 0.05 was considered as significant. Results: Of all patients, 294 (43.5%) were female and rest of them were male. The mean age of patients was 69.3±13.2 years. Of all patients, 25.3% arrived to the hospital in less than 4.5 hours. The difference between arrival time to the hospital in rural and urban patients was significant. The most risk factors were seen in both sexes was HTN and in female only was DM and in male only was CVA. The results of CT and MRI showed that 30% and 64.9% of patients had lesion respectively that of them the most lesion in MRI was SMALL VESSEL and in CT was Middle Cerebral Artery (MCA). Conclusion: Results showed that the patients who live in urban areas arrive to emergency sooner than rural patients. The significant relation was seen between AF, residence place and valvular with arriving time to hospital.


2010 ◽  
Vol 15 (7) ◽  
pp. 848-855 ◽  
Author(s):  
Zewdu Hurissa ◽  
Samuel Gebre-Silassie ◽  
Workagegnehu Hailu ◽  
Tewodros Tefera ◽  
David G Lalloo ◽  
...  

Author(s):  
Lina Díaz-Castro ◽  
Kurt Hoffman ◽  
Héctor Cabello-Rangel ◽  
Armando Arredondo ◽  
Miguel Ángel Herrera-Estrella

Background Schizophrenia (SCH) and bipolar disorder (BD) have both shared and unique genetic risk factors and clinical characteristics. The aim of the present study was to identify potential risk factors significantly associated with SCH, relative to a BD reference group. Methods Data were obtained from medical records of patients that entered a major Mexico City hospital during 2009–2010 presenting psychotic symptoms (n = 1132; 830 cases of SCH, 302 cases of BD; 714 men and 418 women). SCH and BD diagnoses were compared with respect to a number of family and clinical characteristics. Logistic and linear regression analyses were used to respectively identify factors selectively associated with the SCH diagnosis relative to the BD diagnosis and explore the relationship between PANSS scores and parental age at time of birth to the age of SCH onset. Results Patients with SCH showed greater functional impairment than those with BD. Family history of mental illness, premorbid schizoid-like personality, and obstetric trauma were significantly associated with the SCH diagnosis. The association of obstetric trauma with SCH was greatest in male patients with a family history of mental illness. In women, increased paternal and decreased maternal age at time of the patient’s birth were associated with an earlier age of SCH onset. Conclusion Male gender, showing premorbid schizoid-like personality, familial SCH, and obstetric trauma are risk factors that distinguish SCH from BD. Additionally, our results suggest that risk for SCH relative to BD may be importantly influenced by interactions between familial risk, gender, and obstetric trauma.


2017 ◽  
Vol 111 (2) ◽  
pp. 91-97 ◽  
Author(s):  
Patricia Rodrigues Naufal Spir ◽  
Luiz Euribel Prestes-Carneiro ◽  
Elivelton Silva Fonseca ◽  
Aline Dayse ◽  
Rogério Giuffrida ◽  
...  

Author(s):  
Roshan Kamal Topno ◽  
Manas Ranjan Dikhit ◽  
Maneesh Kumar ◽  
. Madhukar ◽  
Kanhaiya Agrawal ◽  
...  

In view of the significant role of Post kala-azar dermal Leishmaniasis (PKDL) patients in the transmission/recurrence of visceral leishmaniasis (VL) outbreaks, control of PKDL is among the priorities. As the Single Dose AmBisome 10 mg/kg (SDA) became the obvious choice for the treatment of VL, therefore, in this study, 896 patients were included to explore the probability of developing PKDL. Among the treated patients, 30 (3.35%) of them found confirmed as PKDL with clinical symptoms. Out of the 30 patients, 53.33% male and 46.67% female patients had macular lesions respectively, with a median time (Interquartile range [IQR]) to development of 13.5 (9–23.5) and 23 (9-17) months following treatment. No, significant associations were established concerning any patient's demographics and clinical characteristics. However, with the patients presenting with confirmed PKDL, females were significantly younger than males. This study suggests the rate of PKDL appearance is directly associated with 10 mg/kg of SDA and therefore there is a need for more concerns regarding doses during treatment.


2020 ◽  
Vol 12 (4) ◽  
pp. 72-77
Author(s):  
T. N. Ermak ◽  
A. V. Kravchenko ◽  
V. I. Shahgil’dyan ◽  
E. N. Ponirovskij ◽  
N. Yu. Gankina

The aim of the work is the clinical characteristics of all known cases of combined visceral leishmaniasis (VL) and HIV infection in the Russian Federation.Results. The article contains information on the problem of the combined course of HIV infection and leishmaniasis: a number of statistical and overview data in the world. A brief description of known cases of high blood pressure in patients with HIV infection in the Russian Federation, as well as a detailed description of the last patient diagnosed with VL in 2019 in Moscow. In all cases, the diagnosis of VL was difficult, which was due to clinical features and the lack of alertness of physicians in relation to VL. All but one of the patients contracted VL during their stay in Crimea.Conclusion. The authors point to the need for the formation of diagnostic alertness among doctors on this pathology, especially since with the expansion of tourist routes abroad in endemic countries, as well as in the Crimea, the relevance of this problem increases.


2020 ◽  
Vol 10 (4) ◽  
pp. 223-231 ◽  
Author(s):  
Jerald Pelayo ◽  
Kevin Bryan Lo ◽  
Ruchika Bhargav ◽  
Fahad Gul ◽  
Eric Peterson ◽  
...  

Introduction: Emerging data have described poor clinical outcomes from infection with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) among African American patients and those from underserved socioeconomic groups. We sought to describe the clinical characteristics and outcomes of acute kidney injury (AKI) in this special population. Methods: This is a retrospective study conducted in an underserved area with a predominance of African American patients with coronavirus disease 2019 (COVID-19). Descriptive statistics were used to characterize the sample population. The onset of AKI and relation to clinical outcomes were determined. Multivariate logistic regression was used to determine factors associated with AKI. Results: Nearly half (49.3%) of the patients with COVID-19 had AKI. Patients with AKI had a significantly lower baseline estimated glomerular filtration rate (eGFR) and higher FiO2 requirement and D-dimer levels on admission. More subnephrotic proteinuria and microhematuria was seen in these patients, and the majority had a pre-renal urine electrolyte profile. Patients with hospital-acquired AKI (HA-AKI) as opposed to those with community-acquired AKI (CA-AKI) had higher rates of in-hospital death (52 vs. 23%, p = 0.005), need for vasopressors (42 vs. 25%, p = 0.024), and need for intubation (55 vs. 25%, p = 0.006). A history of heart failure was significantly associated with AKI after adjusting for baseline eGFR (OR 3.382, 95% CI 1.121–13.231, p = 0.032). Conclusion: We report a high burden of AKI among underserved COVID-19 patients with multiple comorbidities. Those who had HA-AKI had worse clinical outcomes compared to those who with CA-AKI. A history of heart failure is an independent predictor of AKI in patients with COVID-19.


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