scholarly journals Probiotic Lactococcus lactis: A Review

2017 ◽  
Vol 5 (6) ◽  
pp. 556 ◽  
Author(s):  
Priti Khemariya ◽  
Sudhir Singh ◽  
Gopal Nath ◽  
Anil K Gulati
Keyword(s):  
Lactococcus Lactis ◽  
Critical Role ◽  
Cottage Cheese ◽  
Cream Cheese ◽  
Different Types ◽  
Health Promoting ◽  
Fresh Cheese ◽  
Pickled Vegetables ◽  
Probiotic Activity ◽  
Natural Way

Lactococcus lactis plays a critical role in food, dairy and health sectors. In food and dairy industries, it is found in production processes of various fermented products such as sausages, pickled vegetables, beverages such as beer and wine, breads, soymilk kefir, sour milk, butter, cream, fresh cheese and different types of cheeses, like Cheddar, Colby, Cottage cheese, Camembert, cream cheese, Roquefort and Brie. Additionally, there is an increasing interest towards the possible health benefits of the probiotic activity of this organism which generally is species and strain specific and depends upon the survival in gastrointestinal tract with sufficient number. Certain strains have the ability to produce antimicrobial peptide called nisin which exhibits preservative potential. Therefore, application of bacteriocinogenic Lactococcus lactis in food and dairy sectors to preserve foods as a natural way and contributing health promoting attributes due to probiotic activity would definitely fulfil today’s consumer demands. This paper aimed to review the adaptation, antibiotic resistance, therapeutic and preservation potential of bacteriocinogenic and probiotic Lactococcus lactis.

Development of fresh cheese made from coconut milk in combination with cow’s milk

2017 ◽  
Vol 119 (10) ◽  
pp. 2183-2193 ◽  
Author(s):  
Tatsawan Tipvarakarnkoon ◽  
Sangrawee Sornsa-ard ◽  
Wutcharee Imcha
Keyword(s):  
Fat Content ◽  
Coconut Milk ◽  
Cottage Cheese ◽  
Cow’S Milk ◽  
Process Conditions ◽  
Content Type ◽  
Cow's Milk ◽  
Different Types ◽  
Fresh Cheese ◽  
Cheese Curd

Purpose The purpose of this paper is to develop fresh cheese made from different types of coconut milk (fresh, UHT, and reconstituted coconut milk) mixed with pasteurized cow’s milk (50:50) by rennet coagulation. The main aim of this study was to achieve successful formation of cheese curd with fully coconut milk aroma and flavor. Design/methodology/approach Fresh cheese made from different types of coconut milk mixed with cow’s milk (50:50) were developed and compared to fresh cheese made from cow’s milk (100:0). Physicochemical analysis including pH, acidity, percentage of yield, protein and fat content, texture analysis and sensory evaluation has been performed. The nine-point hedonic preference test (n=35) and consumer testing (n=235) were conducted. Findings In comparison, fresh cheese made with the presence of coconut milk (50:50) had higher fat content, lower crude protein content, higher firmness, and adhesiveness than those made from cow’s milk alone (0:100). The cheese with the presence of coconut milk was liked better by consumers (7.35 out of 9). Rehydrated coconut milk was mostly preferred to use among all three types of coconut milk which showed firmer texture and admired flavor. The texture of the developed product was proved to be similar to commercial cottage cheese. Using the rehydrated coconut milk in the formulation gave successful results for making fresh coconut milk cheese, which has also not been used previously in any research. Research limitations/implications In this paper, the effect of process conditions on the quality of cheese curd formation was not yet investigated and discussed. The process parameters including heat treatment and renneting time should be further studied. Originality/value A novel fresh cheese made from coconut milk mixed with pasteurized cow’s milk was successfully developed. The cheese curd was formed with fully coconut milk aroma and flavor.

Accessing resources for service innovation – the critical role of network relationships

2014 ◽  
Vol 25 (1) ◽  
pp. 2-29 ◽  
Author(s):  
Helena Rusanen ◽  
Aino Halinen ◽  
Elina Jaakkola
Keyword(s):  
Critical Role ◽  
Service Innovation ◽  
Innovation Process ◽  
Research Strategy ◽  
Future Research ◽  
Theoretical Understanding ◽  
Resource Access ◽  
Content Type ◽  
External Resources ◽  
Different Types

Purpose – This paper aims to explore how companies access resources through network relationships when developing service innovations. The paper identifies the types of resource that companies seek from other actors and examines the nature of relationships and resource access strategies that can be applied to access each type of resource. Design/methodology/approach – A longitudinal, multi-case study is conducted in the field of technical business-to-business (b-to-b) services. An abductive research strategy is applied to create a new theoretical understanding of resource access. Findings – Companies seek a range of resources through different types of network relationships for service innovation. Four types of resource access strategies were identified: absorption, acquisition, sharing, and co-creation. The findings show how easily transferable resources can be accessed through weak relationships and low-intensity collaboration. Access to resources that are difficult to transfer, instead, necessitates strong relationships and high-intensity collaboration. Research limitations/implications – The findings are valid for technical b-to-b services, but should also be tested for other kinds of innovations. Future research should also study how actors integrate the resources gained through networks in the innovation process. Practical implications – Managers should note that key resources for service innovation may be accessible through a variety of actors and relationships ranging from formal arrangements to miscellaneous social contacts. To make use of tacit resources such as knowledge, firms need to engage in intensive collaboration. Originality/value – Despite attention paid to network relationships, innovation collaboration, and external resources, previous research has neither linked these issues nor studied their mutual contingencies. This paper provides a theoretical model that characterizes the service innovation resources accessible through different types of relationships and access strategies.

scholarly journals Paracrine interactions between epithelial cells promote colon cancer growth

2020 ◽  
Author(s):  
Guillaume Jacquemin ◽  
Annabelle Wurmser ◽  
Mathilde Huyghe ◽  
Wenjie Sun ◽  
Meghan Perkins ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Cancer Cells ◽  
Stromal Cells ◽  
Critical Role ◽  
Essential Factor ◽  
Transcriptional Responses ◽  
Tumour Formation ◽  
Different Types ◽  
The Impact

AbstractTumours are complex ecosystems composed of different types of cells that communicate and influence each other. While the critical role of stromal cells in affecting tumour growth is well established, the impact of mutant cancer cells on healthy surrounding tissues remains poorly defined. Here, we uncovered a paracrine mechanism by which intestinal cancer cells reactivate foetal and regenerative Yap-associated transcriptional programs in neighbouring wildtype epithelial cells, rendering them adapted to thrive in the tumour context. We identified the glycoprotein Thrombospondin-1 (Thbs1) as the essential factor that mediates non-cell autonomous morphological and transcriptional responses. Importantly, Thbs1 is associated with bad prognosis in several human cancers. This study reveals the Thbs1-YAP axis as the mechanistic link mediating paracrine interactions between epithelial cells, promoting tumour formation and progression.

scholarly journals The Role of α-Synuclein Oligomers in Parkinson’s Disease

2020 ◽  
Vol 21 (22) ◽  
pp. 8645
Author(s):  
Xiao-yu Du ◽  
Xi-xiu Xie ◽  
Rui-tian Liu
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Theoretical Basis ◽  
Critical Role ◽  
Treatment Regimens ◽  
Propagation Effects ◽  
Different Types ◽  
Oligomeric Forms ◽  
Neurodegeneration Disease

α-synuclein (α-syn) is a protein associated with the pathogenesis of Parkinson’s disease (PD), the second most common neurodegeneration disease with no effective treatment. However, how α-syn drives the pathology of PD remains elusive. Recent studies suggest that α-syn oligomers are the primary cause of neurotoxicity and play a critical role in PD. In this review, we discuss the process of α-syn oligomers formation and the current understanding of the structures of oligomers. We also describe seed and propagation effects of oligomeric forms of α-syn. Then, we summarize the mechanism by which α-syn oligomers exert neurotoxicity and promote neurodegeneration, including mitochondrial dysfunction, endoplasmic reticulum stress, proteostasis dysregulation, synaptic impairment, cell apoptosis and neuroinflammation. Finally, we investigate treatment regimens targeting α-syn oligomers at present. Further research is needed to understand the structure and toxicity mechanism of different types of oligomers, so as to provide theoretical basis for the treatment of PD.

scholarly journals Experiences of the Urban Green Local Environment as a Factor for Well-Being among Adults: An Exploratory Qualitative Study in Southern Sweden

2019 ◽  
Vol 16 (14) ◽  
pp. 2464 ◽  
Author(s):  
Hanna Weimann ◽  
Jonas Björk ◽  
Carita Håkansson
Keyword(s):  
Local Environment ◽  
Well Being ◽  
Derived Categories ◽  
Outdoor Environment ◽  
Multiple Perspectives ◽  
Social Contacts ◽  
Different Types ◽  
Health Promoting ◽  
The Life Course

The amount and quality of greenness in the local outdoor environment has repeatedly been linked to human well-being. Different types of green areas are likely required in order to meet the various needs of people throughout the course of their lives and with regard to individual social and economic living conditions. The aim of the present study was to increase the understanding of different pathways between green environments, well-being and health. We conducted 16 interviews to explore perceptions and experiences among adults residing in a semi-urban to urban area and derived categories and subcategories from the data using content analysis. We identified six categories; promoting activities, supporting social contacts, stimulating sensory impressions, providing a retreat, offering ways to influence and creating a sense of coherence, and we recognized that the availability to, and contrasts between and maintenance of the environment were experienced as prerequisites for health-promoting properties of the green local environment. The results illustrate a rich variety in potential pathways through which the green local environment may promote well-being. The study highlights the need to plan the local environment from multiple perspectives, as well as carefully considering prerequisites of various kinds in order for the green environment to support health across the life-course.

Critical Role of Supply Chain Decoupling Point in Mass Customisation from Its Upstream and Downstream Information Systems Point of View

2011 ◽  
pp. 185-196
Author(s):  
S. Saghiri
Keyword(s):  
Supply Chain ◽  
Information Systems ◽  
Critical Role ◽  
Point Of View ◽  
Information Flows ◽  
Mass Customisation ◽  
Different Types ◽  
Type Information ◽  
Different Levels

Concentrating on the role of supply chain decoupling point, this chapter introduces different levels of customisation and mass operations and three types of mass customisation. It argues that in each mass customisation type, information systems which are upstream and downstream of the decoupling point can be varied. Consequently, information flows in different types of mass customisation have been examined. This analysis is an endeavour to organise mass customisation information systems across the supply chain, while it can be a useful structure for future researches in this area as well.

Improved Microbiological Assay for Penicillin Residues in Milk and Dairy Products

1978 ◽  
Vol 61 (4) ◽  
pp. 918-922
Author(s):  
Stanley E Katz ◽  
Carol A Fassbender
Keyword(s):  
Phosphoric Acid ◽  
Dairy Products ◽  
Microbiological Assay ◽  
Base Layer ◽  
Cottage Cheese ◽  
Cream Cheese ◽  
Dry Milk ◽  
Nonfat Dry Milk ◽  
Consistent Measurement ◽  
Milk And Dairy Products

Abstract The microbiological assay for penicillin residues in milk was improved. Acidification of milk with phosphoric acid to pH 4.5, centrifugation to remove precipitated proteinaceous matter, adjustment of pH to 6.0, a second centrifugation, and the use of a 2% agar base layer resulted in the consistent measurement of 0.01 unit penicillin activity/ml milk. Sarcina lutea was used as the assay organism. Recoveries in milk averaged 94%, in nonfat dry milk 84%, in cottage cheese 97%, and in cream cheese 94%.

scholarly journals Isolation, identification and antibiotic susceptibility of nis+ Lactococcus lactis from dairy and non-dairy sources

2013 ◽  
Vol 31 (No. 4) ◽  
pp. 323-331 ◽  
Author(s):  
P. Khemariya ◽  
S. Singh ◽  
G. Nath ◽  
A.K. Gulati
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Antimicrobial Agent ◽  
Lactococcus Lactis ◽  
Antibiotic Susceptibility ◽  
Pcr Amplification ◽  
Food Borne ◽  
Antibiotic Susceptibility Test ◽  
Different Types ◽  
Zones Of Inhibition

Eight isolates of Lactococcus lactis subsp. lactis were isolated and identified by phenotypic and molecular characterisation out of 23 isolates of lactic acid bacteria (LAB) from different dairy and non-dairy sources. Out of eight strains, four were obtained from dairy and four from non-dairy sources. All eight strains of L. lactis subsp. lactis were able to produce zones of inhibition against the Lactobacillus acidophilus NCDC 015. The antimicrobial agent produced by the isolates inhibited the growth of a range of related lactic acid bacteria and certain Gram positive food-borne microorganisms. The antimicrobial agent, i.e. nisin, produced by the strains was confirmed by PCR amplification of nisin gene sequences of 174 bp size. Antibiotic susceptibility test to 21 different types of antibiotics was evaluated. All the isolates were resistant to fosfomycin, cefepime, amikacin, kanamycin, neomycin, nalidixic acid, pipemidic acid, norfloxacin, sulphadiazine, colistin, polymixin, teicoplanin, nystatin, and amphotericin B but susceptible to ampicillin, erythromycin, spiramycin, spectinomycin, ciprofloxacin, rifampicin, and trimethoprim.  

Autophagy Defects in Skeletal Myopathies

2020 ◽  
Vol 15 (1) ◽  
pp. 261-285 ◽  
Author(s):  
Marta Margeta
Keyword(s):  
Clinical Presentation ◽  
Critical Role ◽  
Lysosomal Degradation ◽  
Cellular Mechanisms ◽  
Biological Stress ◽  
Evolutionarily Conserved ◽  
Different Types ◽  
Muscle Homeostasis ◽  
Catabolic Process ◽  
Cellular Organelles

Autophagy is an evolutionarily conserved catabolic process that targets different types of cytoplasmic cargo (such as bulk cytoplasm, damaged cellular organelles, and misfolded protein aggregates) for lysosomal degradation. Autophagy is activated in response to biological stress and also plays a critical role in the maintenance of normal cellular homeostasis; the latter function is particularly important for the integrity of postmitotic, metabolically active tissues, such as skeletal muscle. Through impairment of muscle homeostasis, autophagy dysfunction contributes to the pathogenesis of many different skeletal myopathies; the observed autophagy defects differ from disease to disease but have been shown to involve all steps of the autophagic cascade (from induction to lysosomal cargo degradation) and to impair both bulk and selective autophagy. To highlight the molecular and cellular mechanisms that are shared among different myopathies with deficient autophagy, these disorders are discussed based on the nature of the underlying autophagic defect rather than etiology or clinical presentation.

scholarly journals Lifestyles, Depression, Anxiety, and Stress as Risk Factors in Nursing Apprentices: A Logistic Regression Analysis of 1193 Students in Lima, Peru

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Jessica Diaz-Godiño ◽  
Luz Fernández-Henriquez ◽  
Florencia Peña-Pastor ◽  
Patricia Alfaro-Flores ◽  
Gloria Manrique-Borjas ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Nursing Students ◽  
Marital Status ◽  
Depression And Anxiety ◽  
Number Of Children ◽  
Dependent Variables ◽  
Different Types ◽  
Health Promoting ◽  
Normal States

Currently, it is considered that mental disorders are related to different types of chronic pathologies; for this reason, efforts to improve general health should also focus on preserving mental health. Therefore, the objective of this study was to determine through logistic regression if the independent variables (risk factors) such as (X1) age, (X2) sex, (X3) marital status, (X4) number of children, and (X5) occupation have influence on the dependent variables such as lifestyles, depression, anxiety, and stress in Peruvian nursing students. The research study was descriptive, transversal, and prospective; 1193 nursing students from Chorrillos, Ica, and Chincha were evaluated, which constituted the total population for the 2018 semester. The Health Promoting Life Profile-II (HPLP-II) and the Depression and Anxiety Stress Scale-21 (DASS-21) were used as instruments. 53.9% of nursing students had unhealthy lifestyles; however, they presented moderate (19.7%), slight (14.2%), severe (2.5%), and extremely severe (2.4%) anxiety. With respect to depression, it was found that 61.2% and 59.9% of affected students were stressed. A significant association was found only between depression and age (p=0.040) and OR = 2.0 (95% CI 1.3–3.1), anxiety and marital status (p=0.043) and OR = 1.7 (95% CI 1.0–2.6), and lifestyles and sex of the students (p=0.003) and OR = 1.1 (95% CI 1.1–2.3). Finally, it is concluded that Peruvian nursing students showed levels of anxiety ranging from moderate to extremely severe, while most of them had “normal” states of depression and stress and also showed unhealthy lifestyles.

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