scholarly journals Periodontal intervention effects on pregnancy outcomes in women with preeclampsia.

1969 ◽  
Vol 40 (2) ◽  
pp. 177-184
Author(s):  
Julián A. Herrera ◽  
Santiago Vélez Medina ◽  
Rodolfo Molano ◽  
Virna Medina ◽  
Javier E. Botero ◽  
...  
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Hellp Syndrome ◽  
Severe Preeclampsia ◽  
Maternal Complications ◽  
Frequent Finding ◽  
Mild Preeclampsia ◽  
Social Demographic ◽  
Study Inclusion ◽  
Clinical Stability

Objective: To determine the efficacy of periodontal intervention on pregnancy outcome in mild preeclamptic women. Methods: A sample of 60 pregnant women with mild preeclampsia (blood pressure levels < 160/110 mm and proteinuria >300 mg/l in 24 hours urine) from the Hospital Universitario del Valle (Cali, Colombia) was included to the study. Preeclamptic women were randomized in two groups, one with periodontal intervention (PIG, N=28) and another in which the periodontal intervention was practiced after childbirth (NPIG, N=32). Maternal socio-demographic, medical and periodontal data were obtained. PIG included patients in which supragingival and subgingival cleaning within ultrasonic and manual devices were performed after study inclusion. The progression from mild to severe preeclampsia, eclampsia or HELLP syndrome, the number of days of clinical stability and the percentile of birth-weight adjusted for gestational age were evaluated in both groups. Results: Most of the patients (60%) were multigravids. Gestational age at inclusion was 31.8±1.6 weeks. Chronic periodontitis was a frequent finding (61.7%). Social, demographic, medical and periodontal conditions were similar between both groups. Disease progression to severe preeclampsia, eclampsia or HELLP syndrome was also similar (89.2% PIG versus 84.4%, p=0.65) (OR=1.06 IC 95% 0.87-1.29, p=0.65). Days of clinical stability were similar between the groups (median 10 days , range 1-46, PIG versus 12 days, range 1-59, p=0.57) and the percentile of birth weight adjusted with gestational age had no differences between the groups (median percentil 50 range 5-90 PIG versus percentil 55 range 5-95, p=0.73). Conclusion: Periodontal intervention does not seem to harm the health, the severity or alter the frequency on maternal complications in mild preeclampsia subjects.

scholarly journals Outcome of Hypertensive Disorders of Pregnancy

2014 ◽  
Vol 3 (1) ◽  
pp. 46-52
Author(s):  
Akhter Zahan ◽  
Md Nazrul Islam ◽  
Netay Kumer Sharma ◽  
Khadiza Begum ◽  
Kinkon Rani Bhowmik
Keyword(s):  
Birth Weight ◽  
Severe Preeclampsia ◽  
Neonatal Outcomes ◽  
Hypertensive Disorders Of Pregnancy ◽  
Maternal Complications ◽  
Cross Sectional ◽  
Hypertensive Disorders ◽  
Mild Preeclampsia ◽  
Adverse Pregnancy ◽  
The Impact

Hypertension is the most common medical problem encountered in pregnancy and are leading causes of maternal, fetal and neonatal morbidity and mortality worldwide. Definitions, classifications, assessment and management of hypertensive disorders vary considerably in the literature and from country to country. In light of this, we aimed to evaluate different types of hypertensive disorders of pregnancy and to determine the impact of hypertensive disorders of pregnancy (HDP) on maternal, fetal and neonatal outcomes. This Cross Sectional descriptive study was conducted in the Department of Gynaecology and Obstetrics of Community Based Medical College, Mymensingh, Bangladesh from April 2012 to March 2013. All the patients who were diagnosed with HDP and gestational age of 20-40 weeks during the study period were included in the study. Patients with preexisting renal disease, diabetes mellitus, active urinary tract infection or who refused to cooperate with the study were excluded. The data regarding demographic variables, clinical features, pregnancy characteristics, maternal complications, fetal and neonatal outcomes were gathered from available data on medical record files. Edema was the most common clinical symptom. Primipara mothers were predominant in the both mild and severe preeclampsia group. Majority (88%) of mothers in mild preeclampsia group had a history of spontaneous vaginal birth, however 82.9% in severe preeclampsia group by Lower Segment Caesarean Section (LSCS). A higher proportion of mother in mild preeclampsia group delivered at term, whereas 65.7% in severe preeclampsia group delivered preterm. The proportion of maternal complications such as were significantly higher in severe preeclampsia group than those in mild preeclampsia group. Most babies (92%) were born with a birth weight 2500 grams in mild preeclampsia group, while 70% born with birth weight between 1500 - 2499 grams in severe preeclampsia group. All the babies were born with apgar score less than 7 between mild and severe preeclampsia groups. About three quarter (74.3%) of neonates born to women the severe preeclampsia group required resuscitation compared to 40% in mild preeclampsia group. The maternal death, still birth and neonatal death were found higher in severe preeclampsia group than those in mild preeclampsia group. Pregnancies affected by hypertensive disorders require careful monitoring due to the increased risks of adverse pregnancy outcomes. Frequency of severe hypertensive disorders is high in our set up. It is associated with high maternal, fetal and neonatal mortality CBMJ 2014 January: Vol. 03 No. 01 P: 46-52

scholarly journals Factors Influencing Maternal Mortality from Severe Preeclampsia and Eclampsia

2016 ◽  
Author(s):  
Denny Khusen
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Maternal Mortality ◽  
Maternal Death ◽  
Gestational Age ◽  
Post Partum ◽  
Severe Preeclampsia ◽  
Maternal Complications ◽  
History Of ◽  
Post Partum Bleeding

Objective: To analyze risk factor, both clinical and laboratory findings, associated with maternal mortality from severe preeclampsia and eclampsia in Atma Jaya Hospital. Methods: This was a retrospective case control study. All medical records of maternal death associated with severe preeclampsia and eclampsia between 1st January 2009 and 31st December 2011 were obtained and then information about risk factors were collected and tabulated. Risk factor analyzed were maternal age, gestational age, parity, coexisting medical illness (hypertension), antenatal examination status, maternal complications, systolic and diastolic blood pressure at admission, and admission laboratory data. Results: There were 19 maternal deaths associated with severe preeclampsia and eclampsia during period of study (Consisted of 6 cases of eclampsia and 13 cases of severe preeclampsia). Maternal mortality rate for severe preeclampsia and eclampsia were 16.7% and 33.3% respectively. Multivariate analysis identified the following risk factors associated with maternal death: gestation age <32 week, history of hypertension, thrombocyte count < 100.0000/μl, post partum bleeding, acute pulmonary edema, HELLP syndrome, and sepsis. Conclusion: In this study, we found that gestational age, history of hypertension, and platelet count are the cause of maternal mortality. Maternal complications associated with maternal mortality are post partum bleeding, acute pulmonary edema, HELLP syndrome, and sepsis. [Indones J Obstet Gynecol 2012; 36-2: 90-4] Keywords: eclampsia, maternal mortality, preeclampsia

scholarly journals Maternal and perinatal outcome in patients with severe pre eclampsia/ eclampsia with and without HELLP syndrome

2014 ◽  
Vol 1 (4) ◽  
pp. 7-12
Author(s):  
T Gupta ◽  
N Gupta ◽  
J Jain ◽  
S Gupta ◽  
P Bhatia ◽  
...  
Keyword(s):  
Birth Weight ◽  
Hellp Syndrome ◽  
Perinatal Outcome ◽  
P Value ◽  
Maternal Complications ◽  
Singleton Pregnancy ◽  
Prospective Longitudinal Study ◽  
Entire Study ◽  
Group 3 ◽  
Prospective Longitudinal

OBJECTIVE: To evaluate the occurrence of HELLP syndrome inpatients with severe pre eclampsia & eclampsia and to compare the maternal & perinatal outcome in patients with and without HELLP syndrome (partial and true). METHOD: This was a prospective longitudinal study conducted in the Department of Obstetrics & Gynaecology, E.S.I. PGIMSR,NewDelhi from August 2011-April 2013. 50 pregnant women with singleton pregnancy with severe pre eclampsia detected at 28 or more weeks of gestation were enrolled. Patients were divided into three groups: group 1 with severe pre eclampsia, group 2 with severe pre eclampsia with partial HELLP syndrome and group 3 with severe pre eclampsia with true HELLP syndrome. Patients in three groups were compared in regard to maternal complications, gestational age atdelivery, mode ofdelivery, hospital stay andperinatal outcome. RESULTS: Prevalence of HELLP syndrome in severe pre eclampsia was 40% (partial HELLP= 28% and true= 12%). Antenatal and maternal complications were more in true HELLP syndrome patients as compared to other groups. PPH was observed in 40% of entire study group. DIC was found more in true HELLP syndrome patient with high statistically significant p value<0.001 Blood and its product transfusion was more in true HELLP syndrome. There was 100% ICU admission in group 3. In severe pre eclampsia, 11 neonates had birth weight >2.5kg. Where as in partial and true HELLP syndrome, no neonate had birth weight more than 2.5kg.This difference was statistically significant. There was 100% NICU admission in HELLP syndrome, 91.66% in partial HELLP syndrome and 42.3% in severe preeclampsia. The perinatal morbidity and mortality was higher in HELLP syndrome patients than in patient with severe pre eclampsia without HELLP syndrome. CONCLUSION: The study concludes that both maternal and perinatal outcome were adverse in HELLP syndrome than in severe pre eclampsia without HELLP syndrome. DOI: http://dx.doi.org/10.3126/jucms.v1i4.9564 Journal of Universal College of Medical Sciences (2013) Vol.1 No.04: 7-12

Various presentations of preeclampsia at tertiary care hospital of Sindh: A Cross-Sectional Study

2019 ◽  
Vol 15 ◽  
Author(s):  
Feriha Fatima Khidri
Keyword(s):  
Hellp Syndrome ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Previous History ◽  
Cross Sectional Study ◽  
Severe Preeclampsia ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mild Preeclampsia

Background: Preeclampsia is the multi-systemic hypertensive pregnancy disorder accompanied by proteinuria. Objectives: To determine the frequency of different presentations of preeclampsia in tertiary care hospital and find out its risk factors. Materials and Methods: Present study was hospital based cross-sectional study and conducted from 1st August 2015 to 31st July 2016 in Gynaecology and Obstetrics department, Liaquat University of medical and health sciences (LUMHS), Hyderabad after ethical approval. A total of 112 pre-eclamptic women were enrolled during the study period by non-probability consecutive sampling. Patients were divided on the basis of their presentations into mild preeclampsia, severe preeclampsia, antepartum eclampsia, intrapartum eclampsia, HELLP syndrome, postpartum preeclampsia, postpartum eclampsia and atypical preeclampsia/eclampsia. All the socio-demographic factors and clinical variables were noted. Frequency and percentage were calculated for categorical variable and mean/standard deviation (SD) for continuous variables. Results: Of the 112 preeclamptic women, 54.5% admitted with antepartum eclampsia, 12.5% with severe preeclampsia, 8.9% with atypical preeclampsia/eclampsia, 8% with mild preeclampsia, 8% with postpartum eclampsia, 3.6% with HELLP syndrome, 2.7% with intrapartum eclampsia and 1.8% with postpartum preeclampsia. Over all, majority of the patients were primigravida (57%), had gestational age >34 weeks at presentation (58.9%) and <7 antenatal visits (88.3%) during their pregnancy. Over all 17.8% had previous bad obstetrical event, 11.6% had previous history of preeclampsia and 64.3% had consanguineous marriages. Conclusion: Different presentations of preeclampsia may help obstetricians to rule out high risk pregnancies and provide antenatal care to patients earlier to prevent complications to both mother and fetus.

scholarly journals Maternal and perinatal outcome in severe preeclampsia and eclampsia at the Rivers State university teaching hospital, Nigeria

2020 ◽  
Vol 9 (11) ◽  
pp. 4389
Author(s):  
Peter A. Awoyesuku ◽  
Dickson H. John ◽  
Dickson H. John ◽  
Lewis B. Lebara ◽  
Lewis B. Lebara
Keyword(s):  
Birth Weight ◽  
Teaching Hospital ◽  
Gestational Age ◽  
Mode Of Delivery ◽  
Case Fatality ◽  
Severe Preeclampsia ◽  
University Teaching ◽  
State University ◽  
The Mean ◽  
Rivers State

Background: Severe preeclampsia and eclampsia remain a challenge in tropical obstetric practice. It is a major contributor to feto-maternal morbidity and mortality in developing countries. This study seeks to determine the prevalence, associated risk factors and the feto-maternal outcome of severe preeclampsia and eclampsia at the rivers state university teaching hospital (RSUTH).Method: A retrospective study of all women who had severe preeclampsia and eclampsia and were delivered at the RSUTH in a two-year period, 1ST January 2018 to 31ST December 2019, was carried out. Data on patients’ age, parity, education, booking status, gestational age at delivery, diagnosis, complications, mode of delivery and fetal sex, birth weight and Apgar scores were retrieved using structured pro-forma. Data were analyzed using SPSS version 20.Results: There were 4496 deliveries of which 128 had severe preeclampsia and eclampsia, giving a prevalence of 2.85%. Of these, 94 (73.4%) had severe preeclampsia and 34 (26.6%) had eclampsia. The mean age of the women ± SD was 29.84±5.44 years, median parity was para 1, and mean gestational age ± SD was 35.38±3.84 weeks. There were 10 maternal deaths giving case fatality of 7.8%. The mean birth weight ± SD was 2.61±0.91 kg and stillborn rate was 14.4%. There was significant association with maternal age, education, booking status, method of delivery and Apgar score of the baby.Conclusion: The prevalence in this study is high with associated high maternal mortality and stillborn rates. Timely and appropriate intervention including primary management and judicious termination of pregnancy will reduce mortality of mother and fetus.

scholarly journals Evaluation of Maternal Complications in Severe Preeclampsia in a University Hospital in Tirana

2016 ◽  
Vol 4 (1) ◽  
pp. 102-106
Author(s):  
Eriseida Ndoni ◽  
Redi Hoxhallari ◽  
Astrit Bimbashi
Keyword(s):  
Renal Failure ◽  
Caesarean Section ◽  
Pulmonary Edema ◽  
Postpartum Hemorrhage ◽  
Hellp Syndrome ◽  
Placental Abruption ◽  
Severe Preeclampsia ◽  
University Hospital ◽  
Multisystem Disorder ◽  
Maternal Complications

BACKGROUND: Preeclampsia is a hypertensive multisystem disorder of pregnancy that complicates up to 10% of pregnancies worldwide and is one of the leading causes of maternal and perinatal morbidity and mortality.AIM: To evaluate maternal complications associated with severe preeclampsia.METHODS: This is a retrospective cross-sectional study conducted in the UHOG “Koço Gliozheni”, in Tirana. Primary outcomes evaluated: maternal death, eclampsia, stroke, HELLP syndrome, and pulmonary edema. Secondary outcomes: renal failure, admission in ICU, caesarean section, placental abruption, and postpartum hemorrhage. Fisher’s exact test and Chi-squared test were used as statistical methods. RESULTS: In women with severe preeclampsia we found higher rates of complications comparing to the group with preeclampsia. Eclampsia (1.5% vs. 7.1%, P < 0.001), HELLP syndrome (2.4% vs. 11.0%; P < 0.001), stroke (0.5% vs 1.9%, P = 0.105) pulmonary edema (0.25% vs. 1.3%, P = 0.0035), renal failure (0.9% vs. 2.6%, P = 0.107), admission in ICU (19.5% vs. 71.4%, P = 0.007), caesarean section rates (55.5% vs. 77%, P = 0.508), placental abruption (4.3% vs. 7.8%, P = 0.103) and severe postpartum hemorrhage (3.2% vs. 3.9%, P = 0.628). CONCLUSION: Severe preeclampsia is associated with high rates of maternal severe morbidity and early diagnosis and timely intervention can prevent life treating complications.

scholarly journals CHARACTERISTICS OF HELLP SYNDROME IN SEVERE PREECLAMPSIA PATIENTS IN DR. SOETOMO HOSPITAL SURABAYA

2016 ◽  
Vol 51 (4) ◽  
pp. 272
Author(s):  
Warih Angesti P ◽  
Ernawati Ernawati ◽  
Dwi Susanti
Keyword(s):  
Birth Weight ◽  
Maternal Mortality ◽  
Gestational Age ◽  
Apgar Score ◽  
Post Partum ◽  
Cross Sectional Study ◽  
Severe Preeclampsia ◽  
Cross Sectional ◽  
Cesarean Section Delivery ◽  
Minute Apgar Score

Hemolysis, elevated liver enzyme, and low platelet count syndrome (HELLPs) is complication following severe preeclampsia which is one of the three leading causes of maternal mortality in Indonesia. The purpose of this study was to understand the prevalence, characteristics, and post-partum outcome of HELLPs patients who deliver in Dr. Soetomo Hospital in July 2012-June 2013. This study was observational-descriptive, cross sectional study. The population observed was the severe preeclampsia patients who deliver in Dr. Soetomo Hospital and have complete medical data in July 2012-June 2013. study subject taken by total sampling. HELLPs follow the 7% of severe preeclampsia patients. The maternal average age of HELLPs group was 30.2 (19-43), while in non-HELLPs was 30.8 (17-46). Most HELLPs patients were in the first and second pregnancy. The average of gestational age at labor in HELLPs was 33-34 weeks. Both in HELLPs and non-HELLPs most performed Cesarean Section delivery. No post-partum maternal mortality found in HELLPs, but 25% had stillbirth. The average of birth weight in HELLPs was 1994.4 g. First minute Apgar score >7 was 33.3% in HELLPs group. In conclusion, Most HELLPs patients were in the first and second pregnancy, while non-HELLPs were in first pregnancy. The average of gestational age at labor was lower in HELLPs group. Neonates mortality were higher in HELLPs group. The average of birth weight was lower in HELLPs group. First minute Apgar score > 7 was higher in non-HELLP group.

scholarly journals Perbedaan Berat Lahir Bayi Pasien Preeklampsia Berat / Eklampsia Early dan Late Onset di RSUP Dr. M. Djamil Padang

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Rizka Amelia ◽  
Ariadi Ariadi ◽  
Syaiful Azmi
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Early Onset ◽  
Late Onset ◽  
Severe Preeclampsia ◽  
Large For Gestational Age ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

AbstrakPreeklampsia dan eklampsia tidak hanya berdampak bagi ibu, tetapi juga terhadap janin yang dikandungnya, seperti hambatan pertumbuhan janin intrauterin yang dapat dilihat dari berat lahir bayi tersebut. Ibu dengan preeklampsia berat/ eklampsia early onset cenderung melahirkan bayi dengan berat lahir Kecil untuk Masa Kehamilan (KMK), sementara yang  late onset cenderung melahirkan bayi dengan berat lahir Sesuai untuk Masa Kehamilan (SMK) atau bahkan Besar untuk Masa Kehamilan (BMK). Tujuannya penelitian ini adalah menentukan perbedaan berat lahir bayi pasien preeklampsia berat/ eklampsia early dan late onset. Penelitian ini dilaksanakan dari Oktober 2012 sampai Juli 2013 di bagian Rekam Medik RSUP Dr. M. Djamil Padang. Jenis penelitian yang digunakan adalah observasional analitik dengan desain cross sectional. Hasil penelitian menunjukkan bahwa angka kejadian preeklampsia berat/ eklampsia early onset adalah 26,1% dan yang late onset sebanyak 73,9%. Bayi KMK lebih banyak dilahirkan oleh ibu preeklampsia berat/ eklampsia early onset (16,67%) dibandingkan dengan yang  late onset (7,35%). Setelah dilakukan analisis melalui uji chi-square, disimpulkan bahwa tidak ada perbedaan berat lahir bayi antara pasien preeklampsia berat/eklampsia early dan late onset secara signifikan (p>0,05).Kata kunci: preeklampsia berat/eklampsia early onset, preeklampsia berat/eklampsia late onset, berat lahir bayi AbstractPreeclampsia and eclampsia are not only effect to mother, but also influent to the fetus, such as intrauterine fetal growth retardation  which can be seen as baby's birth weight. Mothers with early onset severe preeclampsia / eclampsia tend to give birth small for gestational age  babies, while the late onset tend to give birth normal birth weight or large for gestational age babies. The objective of this study was to determine the differentiation between baby's birth weight of early and late onset severe preeclampsia/ eclampsia. The research was conducted from October 2012 to July 2013 at the medical records department of general hospital center Dr. M. Djamil Padang. The type of this research was observational analytic with cross sectional design. The results showed that the incidence of early onset severe preeclampsia/ eclampsia was 26.1% and late onset was 73.9%. Small for gestational age babies born from mothers with early onset severe preeclampsia/ eclampsia (16.67%) is more than the late onset (7.35%). After analyzed by chi square test, it was concluded that there was no differentiation between baby's birth weight of early and late onset severe preeclampsia/ eclampsia significantly (p> 0,05).Keywords: early onset severe preeclampsia/eclampsia, late onset severe preeclampsia/eclampsia, baby’s birth weight

scholarly journals Evaluation of Factors Affecting Perinatal Mortality in Patients with HELLP Syndrome

2021 ◽  
pp. 1-8
Author(s):  
REYHAN GÜNDÜZ ◽  
SENEM YAMAN TUNÇ ◽  
MEHMET SAİT İÇEN ◽  
SABAHATTİN ERTUĞRUL ◽  
TALİP GÜL
Keyword(s):  
Intensive Care ◽  
Birth Weight ◽  
Perinatal Mortality ◽  
Gestational Age ◽  
Hellp Syndrome ◽  
Neonatal Intensive Care ◽  
Mortality Rates ◽  
Apgar Scores ◽  
Factors Affecting ◽  
Gestational Age At Delivery

OBJECTIVE: To determine the perinatal mortality rate in patients with HELLP syndrome in our clinic and to investigate the factors affecting perinatal mortality. It also makes recommendations to reduce perinatal mortality and contributes to the literature. STUDY DESIGN: Three-hundred-and-eighty-three patients were retrospectively evaluated in this cohort study. The patients' demographic, clinical data, laboratory results, gestational week at delivery, method of delivery, neonatal birth weight, fetal gender, 1- and 5-minute APGAR scores, place of delivery, maternal morbidity, mortality rates, and perinatal mortality rates were recorded. The relationship of these factors with perinatal mortality was investigated. RESULTS: The rate of perinatal mortality was determined as 6%. Patients with HELLP syndrome who experienced perinatal mortality showed significantly lower birth weight, gestational age at delivery, and 1- and 5-minute APGAR score values (p<0.05). With respect to methods of delivery, we determined that vaginal delivery was linked to a significantly higher rate of perinatal mortality (p<0.001). Gestational age at delivery, birth weight, 1- and 5-minute APGAR scores were negatively correlated with perinatal mortality. Logistic regression revealed the APGAR score at 5 minutes as the most reliable independent predictive finding for perinatal mortality. CONCLUSION: We think that to decrease perinatal mortality rates, maternal and fetal well-being in patients with HELLP syndrome should be closely monitored and delivery and follow-up should take place at tertiary health institutions after maternal and neonatal intensive care arrangements are made. Particularly, neonates with low 5-minute APGAR scores in the postpartum evaluation of neonatal condition are recommended to be followed-up at the neonatal intensive care unit.

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