PROBLEMS OF DIAGNOSIS AND TREATMENT OF PATIENTS WITH BACKGROUND PROCESSES AND TUMOR PATHOLOGY OF THE VULVA

Aim. The study was designed for the optimization of the approaches to the diagnosis and management of women with background diseases and tumor pathology of the vulva.Materials and methods. The study involved more than a thousand and a half patients from different regions of Russia and CIS countries with precancerous and tumor pathology of the external genitals. A variety of methods were used in the primary diagnosis and monitoring in the treatment and observation, ranging from the banal examination, palpation, laboratory studies and ending with modern morphological studies, CT, MRI and PET diagnostics.Results. The characteristic differences in the background processes of the vulva were revealed, which allowed us to divide them into two groups: the first group – the pathological process occurs against the background of dystrophic changes in the tissues of the external genitals; the second group – the dermis and subcutaneous fat are not changed. Clear morphological criteria of two variants of changes are accompanied by a significantly different clinical picture. Conservative measures had low efficiency in the pathology of the vulva with a neurodystrophic process. Carrying out a photodynamic therapy and laser vaporization is justified only in young and middle-aged women with precancer. It was found that the high efficiency of surgical treatment is combined with a large number of early and late postoperative complications, which in itself causes discomfort, pain, dysuric phenomena, and dyspareunia. It is possible to reduce the frequency of postoperative complications and improve the functional and cosmetic results of the treatment only with the use of reconstructive plastic surgery. We have developed and widely implemented the methods of closing wound defects in everyday practice and evaluated their effectiveness. Conclusion. Over the past 20 years, a lot of work has been done to address the topical issues related to the diagnosis and treatment of background processes, precancer and vulva cancer. However, at present, there is no center where theoretical issues are studied at a serious level, conservative and invasive methods of treatment are developed, and educational and methodical work with doctors is carried out. Without proper attention to these issues, this problem is unlikely to be solved in the near future, both from theoretical and practical points of view.

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THE EFFECT OF LENGTH OF DAY AND TEMPERATURE ON THE DEPOSITION OF SUBCUTANEOUS FAT BY MARKET TURKEYS

Canadian Journal of Animal Science ◽

10.4141/cjas63-046 ◽

1963 ◽

Vol 43 (2) ◽

pp. 332-336 ◽

Cited By ~ 5

Author(s):

R. M. Blakely ◽

H. I. MacGregor

Keyword(s):

Ambient Temperature ◽

High Efficiency ◽

Subcutaneous Fat ◽

Factorial Experiment ◽

Day Length ◽

Feed Consumption ◽

Length Of Day ◽

Finishing Diets ◽

Low Efficiency ◽

Lower Temperature

A 2 × 2 × 2 factorial experiment, involving a total of 400 21-week-old Broad Breasted Bronze turkey males, was undertaken, using two buildings differing in temperature, two lengths of day (9 and 14 hours), and two finishing diets (low and high efficiency). Feed consumption, gain in weight, feed-gain ratio, and carcass score were all higher for the lower temperature location. Ambient temperature differences had a greater effect on the high efficiency diet than on the low efficiency diet. Length of day had no overall effect on the above criteria. Interactions between the low and high efficiency diets, and day length, were demonstrated.

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CHROMOSOMAL BASIS OF THE MEROZYGOSITY IN A PARTIALLY DIPLOID MUTANT OF PNEUMOCOCCUS

Genetics ◽

10.1093/genetics/80.4.667 ◽

1975 ◽

Vol 80 (4) ◽

pp. 667-678

Author(s):

Mary Lee S Ledbetter ◽

Rollin D Hotchkiss

Keyword(s):

High Efficiency ◽

Point Mutations ◽

Resistant Mutant ◽

Chromosomal Marker ◽

Structural Abnormality ◽

C Cells ◽

Wild Type ◽

Chromosomal Locus ◽

Low Efficiency ◽

Derivatives Of

ABSTRACT A sulfonamide-resistant mutant of pneumococcus, sulr-c, displays a genetic instability, regularly segregating to wild type. DNA extracts of derivatives of the strain possess transforming activities for both the mutant and wild-type alleles, establishing that the strain is a partial diploid. The linkage of sulr-c to strr-61, a stable chromosomal marker, was established, thus defining a chromosomal locus for sulr-c. DNA isolated from sulr-c cells transforms two mutant recipient strains at the same low efficiency as it does a wild-type recipient, although the mutant property of these strains makes them capable of integrating classical "low-efficiency" donor markers equally as efficiently as "high efficiency" markers. Hence sulr-c must have a different basis for its low efficiency than do classical low efficiency point mutations. We suggest that the DNA in the region of the sulr-c mutation has a structural abnormality which leads both to its frequent segregation during growth and its difficulty in efficiently mediating genetic transformation.

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A Brief Review on Solvent-Free Synthesis of Zeolites

Materials ◽

10.3390/ma14040788 ◽

2021 ◽

Vol 14 (4) ◽

pp. 788

Author(s):

Jinlin Mei ◽

Aijun Duan ◽

Xilong Wang

Keyword(s):

High Efficiency ◽

Raw Materials ◽

Solvent Free ◽

High Yield ◽

Control Synthesis ◽

Mechanical Mixing ◽

Synthesis Mechanism ◽

Wastewater Pollution ◽

Low Efficiency ◽

Solvent Free Synthesis

The traditional hydrothermal method to prepare zeolite will inevitably use a large amount of water as a solvent, which will lead to higher autogenous pressure, low efficiency, and wastewater pollution. The solvent-free method can be used to synthesize various types of zeolites by mechanical mixing, grinding, and heating of solid raw materials, which exhibits the apparent advantages of high yield, low pollution, and high efficiency. This review mainly introduces the development process of solvent-free synthesis, preparation of hierarchical zeolite, morphology control, synthesis mechanism and applications of solvent-free methods. It can be believed that solvent-free methods will become a research focus and have enormous industrial application potential.

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Inter-professional agreement and collaboration between extended scope physiotherapists and orthopaedic surgeons in an orthopaedic outpatient shoulder clinic – a mixed methods study

BMC Musculoskeletal Disorders ◽

10.1186/s12891-020-03831-z ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Merete Nørgaard Madsen ◽

Maria Lange Kirkegaard ◽

Thomas Martin Klebe ◽

Charlotte Lorenzen Linnebjerg ◽

Søren Martin Riis Villumsen ◽

...

Keyword(s):

Treatment Plan ◽

Random Order ◽

Primary Diagnosis ◽

Diagnosis And Treatment ◽

List Type ◽

Professional Collaboration ◽

Relational Coordination ◽

Orthopaedic Surgeons ◽

Link Type ◽

Shoulder Disorders

Abstract Background Extended scope physiotherapists (ESP) are increasingly supplementing orthopaedic surgeons (OS) in diagnosing patients with musculoskeletal disorders. Studies have reported satisfactory diagnostic and treatment agreement between ESPs and OSs, but methodological study quality is generally low, and only few studies have evaluated inter-professional collaboration. Our aims were: 1) to evaluate agreement on diagnosis and treatment plan between ESPs and OSs examining patients with shoulder disorders, 2) to explore and evaluate their inter-professional collaboration. Methods In an orthopaedic outpatient shoulder clinic, 69 patients were examined independently twice on the same day by an ESP and an OS in random order. Primary and secondary diagnoses (nine categories) and treatment plan (five categories, combinations allowed) were registered by each professional and compared. Percentage of agreement and kappa-values were calculated. Two semi-structured focus-group interviews were performed with ESPs and OSs, respectively. Interviews were based on the theoretical concept of Relational Coordination, encompassing seven dimensions of communication and relationship among professionals. A thematic analysis was conducted. Results Agreement on primary diagnosis was 62% (95% CI: [50; 73]). ESPs and OSs agreed on the combination of diagnoses in 79% (95% CI: [70; 89]) of the cases. Partial diagnostic agreement (one professional’s primary diagnosis was also registered as either primary or secondary diagnosis by the other) was 96% (95% CI: [91; 100]). Across treatment categories, agreement varied between 68% (95% CI: [57; 79]) and 100%. In 43% (95% CI: [31; 54]) of the cases, ESP and OS had full concordance between treatment categories chosen, while they agreed on at least one recommendation in 96% (95% CI: [91; 100]). Positive statements of all dimensions of relational coordination were found. Three themes especially important in the inter-professional collaboration emerged: Close communication, equal and respectful relationship and professional skills. Conclusions In the majority of cases, the ESP and OS registered the same or partly the same diagnosis and treatment plan. Indications of a high relational coordination implying a good inter-professional collaboration were found. Our results support that ESPs and OSs can share the task of examining selected patients with shoulder disorders in an orthopaedic clinic. Trial registration ClinicalTrials.gov Identifier: NCT03343951. Registered 10 November 2017

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Inflight Transmission of COVID-19 Based on Experimental Aerosol Dispersion Data

Journal of Travel Medicine ◽

10.1093/jtm/taab023 ◽

2021 ◽

Author(s):

Zhaozhi Wang ◽

Edwin R Galea ◽

Angus Grandison ◽

John Ewer ◽

Fuchen Jia

Keyword(s):

High Efficiency ◽

Face Mask ◽

Generation Rate ◽

Aviation Industry ◽

Filtration System ◽

Dispersion Data ◽

Low Probability ◽

Meal Service ◽

Low Efficiency ◽

Aerosol Dispersion

Abstract Background An issue of concern to the travelling public is the possibility of in-flight transmission of COVID-19 during long- and short-haul flights. The aviation industry maintains that the probability of contracting the illness is small based on reported cases, modelling and data from aerosol dispersion experiments conducted on-board aircraft. Methods Using experimentally derived aerosol dispersion data for a B777–200 aircraft and a modified version of the Wells-Riley equation we estimate inflight infection probability for a range of scenarios involving quanta generation rate and face mask efficiency. Quanta generation rates were selected based on COVID-19 events reported in the literature while mask efficiency was determined from the aerosol dispersion experiments. Results The MID-AFT cabin exhibits the highest infection probability. The calculated maximum individual infection probability (without masks) for a 2-hour flight in this section varies from 4.5% for the ‘Mild Scenario’ to 60.2% for the ‘Severe Scenario’ although the corresponding average infection probability varies from 0.1% to 2.5%. For a 12-hour flight, the corresponding maximum individual infection probability varies from 24.1% to 99.6% and the average infection probability varies from 0.8% to 10.8%. If all passengers wear face masks throughout the 12-hour flight, the average infection probability can be reduced by approximately 73%/32% for high/low efficiency masks. If face masks are worn by all passengers except during a one-hour meal service, the average infection probability is increased by 59%/8% compared to the situation where the mask is not removed. Conclusions This analysis has demonstrated that while there is a significant reduction in aerosol concentration due to the nature of the cabin ventilation and filtration system, this does not necessarily mean that there is a low probability or risk of in-flight infection. However, mask wearing, particularly high-efficiency ones, significantly reduces this risk.

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High Efficiency Generalized Parallel Counters for Look-Up Table Based FPGAs

International Journal of Reconfigurable Computing ◽

10.1155/2015/518272 ◽

2015 ◽

Vol 2015 ◽

pp. 1-16 ◽

Cited By ~ 4

Author(s):

Burhan Khurshid ◽

Roohie Naaz Mir

Keyword(s):

Power Dissipation ◽

High Speed ◽

High Efficiency ◽

Critical Path ◽

Fir Filters ◽

Path Delay ◽

Look Up Table ◽

Improved Performance ◽

Ip Cores ◽

Low Efficiency

Generalized parallel counters (GPCs) are used in constructing high speed compressor trees. Prior work has focused on utilizing the fast carry chain and mapping the logic onto Look-Up Tables (LUTs). This mapping is not optimal in the sense that the LUT fabric is not fully utilized. This results in low efficiency GPCs. In this work, we present a heuristic that efficiently maps the GPC logic onto the LUT fabric. We have used our heuristic on various GPCs and have achieved an improvement in efficiency ranging from 33% to 100% in most of the cases. Experimental results using Xilinx 5th-, 6th-, and 7th-generation FPGAs and Stratix IV and V devices from Altera show a considerable reduction in resources utilization and dynamic power dissipation, for almost the same critical path delay. We have also implemented GPC-based FIR filters on 7th-generation Xilinx FPGAs using our proposed heuristic and compared their performance against conventional implementations. Implementations based on our heuristic show improved performance. Comparisons are also made against filters based on integrated DSP blocks and inherent IP cores from Xilinx. The results show that the proposed heuristic provides performance that is comparable to the structures based on these specialized resources.

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Building Self-Service Printing System on College Educational Administration

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.889-890.1262 ◽

2014 ◽

Vol 889-890 ◽

pp. 1262-1265

Author(s):

Chun Fang Shi

Keyword(s):

Educational Administration ◽

High Efficiency ◽

Ic Card ◽

Hardware System ◽

Teachers And Students ◽

Human Cost ◽

Printing System ◽

Background Database ◽

Self Service ◽

Low Efficiency

Printing system of college educational administration has been managed by artificial, which result in low efficiency and high human cost. So we build a system by docking the software and hardware system of background database based on IC card to realize self-service printing for teachers and students of college, which provide a high-efficiency, convenient and humanized service mode, and enhane the economical sense of teachers and students for creating a green campus.

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Indications for Dialysis in Acute Kidney Injury

10.2310/nephro.12038 ◽

2020 ◽

Author(s):

Ankit Patel ◽

Kenneth B Christopher

Keyword(s):

Acute Kidney Injury ◽

Renal Replacement Therapy ◽

Replacement Therapy ◽

High Efficiency ◽

Kidney Injury ◽

Intermittent Hemodialysis ◽

Continuous Venovenous Hemofiltration ◽

Continuous Venovenous Hemodialysis ◽

Low Efficiency ◽

The Impact

Renal replacement therapy (RRT) can be used to support patient’s kidney function in cases of acute kidney injury (AKI). However, timing, modality, and dosing of RRT continue to remain in question. Recent studies have begun to provide data to help guide clinicians on when to initiate RRT, what form of RRT to use ranging from continuous venovenous hemofiltration (VVH) to intermittent hemodialysis, and the impact of high versus low-intensity dosing. Additionally, the risks associated with temporary vascular access with regard to thrombosis and infection, the impact of high efficiency and flux versus low efficiency and flux membranes, and options for anticoagulation in RRT for AKI are also discussed. This review contains 75 references. Key words: acute kidney injury, chronic kidney disease, continuous venovenous hemofiltration, continuous venovenous hemodialysis, renal replacement therapy, venovenous hemofiltration,

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Insights from Past Trends in Exergy Efficiency and Carbon Intensity of Electricity: Portugal, 1900–2014

Energies ◽

10.3390/en12030534 ◽

2019 ◽

Vol 12 (3) ◽

pp. 534

Author(s):

Laura Felício ◽

Sofia T. Henriques ◽

André Serrenho ◽

Tiago Domingos ◽

Tânia Sousa

Keyword(s):

World War I ◽

High Efficiency ◽

Electricity Production ◽

Transport Sector ◽

Carbon Intensity ◽

Renewable Electricity ◽

World War ◽

Residential Sector ◽

Electricity Use ◽

Low Efficiency

We use the societal exergy analysis to identify periods and factors controlling efficiency dilution and carbon deepening of electricity in Portugal from 1900 to 2014. Besides estimating the carbon intensity of electricity production, we propose a new indicator, the carbon intensity of electricity use, which quantifies CO2/kWh of electricity derived useful exergy. Results show final to useful efficiency dilution until World War I (50% to 30%) due to a decrease in share of the high-efficiency transport sector and from mid-1940s to 1960 and mid-1990s onwards (58% to 47% and 47% to 40%) due to an increase in share of the low efficiency commercial and residential sector. Decarbonization from 1900 to mid-1960s, with carbon intensities of electricity production and use dropping respectively from 12.8 to 0.2 and from 33.6 to 0.4 kg CO2/kWh due to an increase in thermoelectricity efficiencies and an increase in share of hydro. Then, a period of carbon deepening until 1990 with carbon intensities tripling due to a shift in shares from hydro to thermoelectricity and more recently a period of decarbonization with carbon intensities decreasing to 0.35 and 0.9 kg CO2/kWh, due to the increase in renewable electricity despite a dilution in final to useful efficiency.

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Efficiency and Persistence of Movento® Treatment against Myzus persicae and the Transmission of Aphid-Borne Viruses

Plants ◽

10.3390/plants10122747 ◽

2021 ◽

Vol 10 (12) ◽

pp. 2747

Author(s):

Thomas Armand ◽

Luâna Korn ◽

Elodie Pichon ◽

Marlène Souquet ◽

Mélissandre Barbet ◽

...

Keyword(s):

Sugar Beet ◽

Myzus Persicae ◽

High Efficiency ◽

Plant Protection ◽

Management Strategies ◽

Plant Protection Products ◽

Viral Transmission ◽

The European Union ◽

Low Efficiency ◽

The Impact

Neonicotinoids are widely used to protect fields against aphid-borne viral diseases. The recent ban of these chemical compounds in the European Union has strongly impacted rapeseed and sugar beet growing practices. The poor sustainability of other insecticide families and the low efficiency of prophylactic methods to control aphid populations and pathogen introduction strengthen the need to characterize the efficiency of new plant protection products targeting aphids. In this study, the impact of Movento® (Bayer S.A.S., Leverkusen, Germany), a tetrameric acid derivative of spirotetramat, on Myzus persicae and on viral transmission was analyzed under different growing temperatures. The results show (i) the high efficiency of Movento® to protect rapeseed and sugar beet plants against the establishment of aphid colonies, (ii) the impact of temperature on the persistence of the Movento® aphicid properties and (iii) a decrease of approximately 10% of the viral transmission on treated plants. These observations suggest a beneficial effect of Movento® on the sanitary quality of treated crops by directly reducing primary infections and indirectly altering, through aphid mortality, secondary infections on which the spread of disease within field depends. These data constitute important elements for the future development of management strategies to protect crops against aphid-transmitted viruses.

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