Comparative Pharmacognostical Evaluation of Khadirashtaka yavakuta (Powder) and Kashaya (Decoction)

2017 ◽  
Vol 9 (10) ◽  
Author(s):  
Chandani Goswami ◽  
V. D. Hitesh Vyas ◽  
Harisha C. R.
Keyword(s):  
Dietary Habits ◽  
Prolonged Exposure ◽  
Skin Diseases ◽  
Metabolic Changes ◽  
Skin Disorders ◽  
Coarse Powder ◽  
Crude Drugs ◽  
Standard Range

Khadirashtaka Kashaya, a compound Ayurvedic formulation is prescribed mainly in the management of Kushtha Vyadhi( skin diseases), Visarp Roga (erysipelous) and Masoorika (type of measels) and it is mentioned in Sangraha Grantha like, Yogaratnakara, Gadanighraha, Bhaishajya Ratnavali. The era is rising with many of novel dietary habits and lifestyle which are ill-assorted with health. Consumption of incompatible food combinations, heavy meals; faulty temperature acclimatisation leads to several metabolic changes which results in unhealthy skin. Their prolonged exposure leads to long lasting dermatological abnormalities having vitiated Rasa and Rakta Dhatu. Khadirashtaka Kashaya helps to break the pathogenesis of skin disorders by its bitter-astringent taste, light and dry properties as well as blood purifying activity. Till date no work was found having comparatively scientifically analysed on this drug. In Present study Khadirashtaka Kashaya and Khadirashtaka choorna have been evaluated for Pharmacognostical analysis. Finished product microscopy and decoction showing the quality and genuineness of all the constituents of Khadirashtaka Kashaya (Decoction) has been done. Organoleptic features of coarse powder made out of the crude drugs were within the standard range

scholarly journals Frequency and types of skin disorders and associated diabetes mellitus in elderly Jordanians

2021 ◽  
Vol 8 (4-5) ◽  
pp. 574-578
Author(s):  
F. Najdawi ◽  
M. Fa'ouri
Keyword(s):  
Diabetes Mellitus ◽  
Bacterial Infection ◽  
Fungal Infection ◽  
Skin Disorder ◽  
Skin Diseases ◽  
The Elderly ◽  
Skin Lesions ◽  
Skin Disorders ◽  
Patients With Diabetes ◽  
Considerable Morbidity

A retrospective study of 232 elderly patients seen between August 1998 and April 2000 at the skin clinic in Princess Haya hospital, Aqaba, was undertaken to determine the prevalence of skin disorders, and those most commonly associated with diabetes mellitus, in the elderly. Eczema/dermatitis was the commonest skin disorder seen [25.9% of cases], followed by pruritus without skin lesions [15.1%], viral infection [14.7%, most commonly herpes zoster], fungal infection [13.8%], and bacterial infection [10.3%]. Bacterial infection was the commonest skin disorder in patients with diabetes mellitus [62.5%], followed by fungal infection [50.0%]. Skin diseases cause considerable morbidity in elderly people; health promotion and education can do much to reduce the risks of these disorders in the elderly, especially those with diabetes

Survey of the Professional Interrelations between Dermatologist and Pharmacist

1986 ◽  
Vol 20 (11) ◽  
pp. 876-880 ◽  
Author(s):  
Oscar E. Araujo ◽  
Debbie A. DeSantis ◽  
Paul L. Doering
Keyword(s):  
Inventory Control ◽  
Community Pharmacist ◽  
National Survey ◽  
Skin Diseases ◽  
Skin Disorders ◽  
Common Skin ◽  
Prescription Refill

A national survey of dermatologists and pharmacists was conducted to characterize the involvement of the community pharmacist in the area of skin diseases and to elicit suggestions to improve professional interrelations. The results show the dermatologists' major complaint is pharmacists' inability or unwillingness to compound prescriptions. The study clearly indicates the need for increased communication between the two professions in matters such as inventory control, prescription refill procedures, and substitution guidelines. The pharmacists, in general, admitted a deficiency in their educational preparedness to recognize common skin disorders, thus limiting their ability to assess the severity of patients' complaints.

Silica-based nanosystems for therapeutic applications in the skin

Nanomedicine ◽  
2019 ◽  
Vol 14 (16) ◽  
pp. 2243-2267 ◽  
Author(s):  
Francisco Arriagada ◽  
Santi Nonell ◽  
Javier Morales
Keyword(s):  
Genetic Factors ◽  
Skin Diseases ◽  
Clinical Applications ◽  
Pharmaceutical Sciences ◽  
Skin Disorders ◽  
Therapeutic Applications ◽  
Improve Treatment ◽  
Promising Tool ◽  
Made In ◽  
Improve Treatment Efficacy

Aging, exposure to oxidants, infectious pathogens, inflammogens, ultraviolet radiation and other environmental and genetic factors can result in the development of various skin disorders. Despite immense progress being made in dermatological treatments, many skin-associated problems still remain difficult to treat and various therapies have limitations. Progress in silica-based nanomaterials research provides an opportunity to overcome these drawbacks and improve therapies and is a promising tool for inclusion in clinical practice to treat skin diseases. This review focuses on the use of various types of silica nanoparticles with therapeutic applications in various skin disorders. These nanosystems improve treatment efficacy by maintaining or enhancing the effect of several drugs and are useful tools for nanomedicine, pharmaceutical sciences and future clinical applications.

scholarly journals Biochemical status of blood of dogs with atopic dermatitis in the conditions of private veterinary clinic “Alfa vet” m. Konotop

2021 ◽  
pp. 29-31
Author(s):  
Olga Stotska ◽  
Oksana Shkromada ◽  
Aleksandr Stockiy
Keyword(s):  
Atopic Dermatitis ◽  
Reference Values ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Skin Diseases ◽  
Clinical Manifestations ◽  
Metabolic Changes ◽  
The Body ◽  
Veterinary Clinic ◽  
Gamma Glutamyltransferase

Metabolic changes in the body of dogs with atopic dermatitis and the causes of its occurrence still remain poorly understood. This study confirms the need for biochemical blood tests for the differential diagnosis of skin diseases in animals. The aim of the research. To identify metabolic changes in dogs with atopic dermatitis. Methods. Serum samples from five ill animals and five intact animals were tested. The diagnosis of the nosological form of skin lesions was established based on the results of anamnesis and clinical manifestations of the disease. Additionally, biochemical studies of the serum of sick animals were performed. Blood of dogs (n=5) was taken from the anterior subcutaneous vein of the forearm or the lateral subcutaneous vein of the tibia into blood tubes. Results. In the study of mineral metabolism, it was found that the concentration of inorganic phosphorus in the serum of sick animals is reduced by only 0.01 mmol/l, but the concentration of total calcium by 10.0 %. The concentration of cholesterol increases 1.3 times and exceeds the reference values by 0.16 mmol/l. In the blood of sick animals, the activity of alanine aminotransferase is significantly reduced by 21.0 % and aspartate aminotransferase – by 20.0 % compared to intact animals. The enzyme gamma-glutamyltransferase probably increases by 1.51 times (P<0.05) in sick dogs, but does not exceed the reference values. Conclusions. It was found that in atopic dermatitis in the serum of dogs decreases the activity of alanine aminotransferase by 21.0 % and aspartate aminotransferase – by 20.0 %, while the activity of gamma-glutamyltransferase increases 1.51 times. The results show the toxic effect of an allergic agent on animals, especially on the liver, which confirms the previous diagnosis – atopic dermatitis.

scholarly journals Prevalence of paediatric dermatoses among patients attending Dermatology outpatient department in a tertiary care hospital in Puducherry

2018 ◽  
Vol 4 (3) ◽  
pp. 368
Author(s):  
Varsha Medasani ◽  
Paquirissamy Oudeacoumar ◽  
Rao Chitralekhya ◽  
Saurabh Krishna Misra
Keyword(s):  
Dietary Habits ◽  
Skin Diseases ◽  
Tertiary Care Hospital ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Outpatient Department ◽  
Care Hospital ◽  
Age Group ◽  
Major Health Problem ◽  
Pigmentary Disorders

<p class="abstract"><strong>Background:</strong> Skin diseases are a major health problem in the paediatric age group and are associated with significant morbidity. Dermatoses in children are more influenced by socioeconomic status, dietary habits, climatic exposure and external environment as compared to adults. The present study was undertaken to know the prevalence of paediatric dermatoses among patients attending Dermatology outpatient department in a tertiary care hospital in Puducherry.</p><p class="abstract"><strong>Methods:</strong> All newly diagnosed, untreated male and female paediatric patients (from neonates to adolescents ≤19 years of age) attending Dermatology OPD, from October 2015 to September 2017 were evaluated to study the prevalence and patterns of paediatric dermatoses. The skin disorders were classified into groups like infections, infestations, eczemas, acne, hypersensitivity disorders, sweat gland disorders, pigmentary disorders, nevi, keratinisation disorders, hair and scalp disorders, papulosquamous disorders, bullous disorders, nail disorders, drug reactions, other dermatoses.<strong></strong></p><p class="abstract"><strong>Results:</strong> The prevalence of pediatric dermatoses in our OPD is 25.21%. Incidence of pediatric dermatoses was found to be more in males 237 (59.39%) than in females 162 (40.60%) and the majority of the patients were in adolescent age group (217; 54.38%). Present study showed that majority of cases belonged to the lower socioeconomic group 186(46.6 %). In our study, majority (58.98%) of dermatoses belonged to infections and infestations group. Of the infective dermatoses, fungal infections (27.88%) were the most common.</p><p><strong>Conclusions:</strong> Infectious dermatoses were commonly seen in this study that may be due to poverty, overcrowding, poor hygiene. There is an increasing trend of fungal infections which might be related to hygiene and environment. </p>

scholarly journals Ceramides: Where do we stand?

2021 ◽  
Vol 1 ◽  
pp. 44
Author(s):  
Nidhi Yadav ◽  
Bhushan Madke ◽  
Anupam Das
Keyword(s):  
Atopic Dermatitis ◽  
Barrier Function ◽  
Skin Diseases ◽  
Acne Vulgaris ◽  
Skin Aging ◽  
Skin Disorders ◽  
Healthy Skin ◽  
Epidermal Barrier ◽  
Inflammatory Dermatoses ◽  
Integral Component

Ceramides are an integral component of the epidermal barrier system. Alterations in ceramides levels are associated with various inflammatory dermatoses such as psoriasis, atopic dermatitis, ichthyosis, Gaucher’s disease, acne vulgaris, and skin aging. Various formulations containing ceramides have been developed so that exogenous ceramides can repair the barrier function. Herein, the authors have provided an overview of the basic anatomy, structure, functioning, and importance of ceramides and their role in healthy skin and various skin disorders. In addition, the authors review conventional and newer technologies for delivery of ceramides in various skin diseases.

scholarly journals DETERMINAN KELUHAN GANGGUAN KULIT PADA PEMULUNG SAMPAH DI TPA KELURAHAN TERJUN KECAMATAN MEDAN MARELAN TAHUN 2019

2019 ◽  
Vol 2 (1) ◽  
pp. 48-55
Author(s):  
Famita Rawati Siboro
Keyword(s):  
Personal Protective Equipment ◽  
Skin Diseases ◽  
Sampling Technique ◽  
Work Behavior ◽  
Personal Hygiene ◽  
Disposal Site ◽  
P Value ◽  
Protective Equipment ◽  
Skin Disorders ◽  
Cross Sectional

Skin disease is a disease related to the environment and human behavior. The incidence of skin diseases has increased because the cause of the disease is alive and breeding in landfills and poor waste collection. This is based on the environment of scavenger workers who have materials that can cause various kinds of skin disorders. Based on the results of preliminary surveys that have been carried out, the number of scavengers in the final disposal site of Kelurahan Falls is 75 people with different age characteristics, different levels of education and length of work. The problem at TPA Falls is work behavior on waste pickers. From observations from the field observations found that the scavenger working conditions in the garbage dump in the Kelurahan Falls generally suffer from skin disorders due to personal hygiene (skin, foot, nail and hand hygiene) which are not given enough attention and the use of Personal Protective Equipment (PPE) that is incorrect and incomplete. The purpose of this study was to determine knowledge, attitudes, actions to use personal protective equipment (PPE) and habits of personal hygiene, length of work, as well as the distance of the house from the landfill with complaints of skin disorders in the garbage scavengers in the TPA Kelurahan Falls. The research method is cross sectional which was analyzed using the Chi-Square test. The research location was conducted at TPA Kelurahan Terjun, Medan Marelan Subdistrict and was conducted in February and March 2019. 75 respondents were taken using simple random sampling technique. The research instrument was in the form of a questionnaire. The results of the study are variables that are not related to complaints of skin disorders that is length of work (P value = 0.617), while variables related to complaints of skin disorders are distance of residents' homes (P value = 0,000), non-compliance using PPE (P value = 0,000) do personal hygiene (P value = 0,000). Suggestions for scavengers to behave more clean and healthy life by maintaining health, personal hygiene and the environment, and using personal protection that must be worn at work.

scholarly journals Prevalence of Dermatoses in Rural Paediatric Population

2013 ◽  
Vol 2 (1) ◽  
pp. 9-14
Author(s):  
Md Hadiuzzaman ◽  
Muhammad Hasibur Rahman ◽  
Nahida Islam ◽  
Md Shahidul Islam ◽  
Sabrina Alam Mumu ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Pediatric Population ◽  
Paediatric Population ◽  
Medical College Hospital ◽  
Health Improvement ◽  
Skin Disorders ◽  
Community Based ◽  
College Hospital ◽  
Medical College ◽  
Patient Department

The spectra of the prevalence of skin diseases vary worldwide and from country to country. Therefore the information about the local prevalence of diseases is very important in helping the development of appropriate health improvement policies for promotion of better management. To document the types of skin disorders prevalent among rural children attending the Community Based Medical College Hospital out patient department, Mymensigh, a defined population based study was undertaken. The medical register from the Hospital was used to obtain information on pattern and outcome of skin diseases seen from January 2010 to December 2011. The frequency of pediatric dermatoses and their distribution patterns were studied. The results revealed that out of the 9279 Patients attending Dermatology out patient department of Community Based Medical College Hospital, 1753 (18.89%) Children were identified with involvement of skin diseases. Age range related to disease was found between one day old to 14 years. The most frequent skin condition was exposure to fungal diseases which was 25.67% followed by scabies 24.10% and eczema 20.25%. Infectious skin diseases represent considerably a high percentage of skin disorders encountered in pediatric population. DOI: http://dx.doi.org/10.3329/cbmj.v2i1.14175 Community Based Medical Journal Vol.2(1) 2013 9-14

scholarly journals PREVALENCE OF CHILDHOOD SKIN DISORDERS ATTENDING AT OUTPATIENT PEDIATRIC HOSPITAL

2020 ◽  
pp. 131-135
Author(s):  
NANDINI THUMMANAPALLY ◽  
KAVITHA LAWDYAVATH ◽  
CHARANDAS GURUVA ◽  
DEEPTHI ENUMULA ◽  
SASTRY PVK ◽  
...  
Keyword(s):  
Rural Area ◽  
Bacterial Infections ◽  
Viral Infections ◽  
Skin Diseases ◽  
Fungal Infections ◽  
Pediatric Population ◽  
Parasitic Infections ◽  
Skin Disorders ◽  
Prior Approval ◽  
Bacterial Skin Infections

Objective: The objective of the study was to study the prevalence of various skin diseases in pediatric population. Methods: A prospective observational study was conducted at private children’s outpatient clinic in Warangal from March to August 2018 with the prior approval from the Institutional Ethical Committee BIPS/IEC/2018/P8. A total of 200 patients with various skin diseases of age group <17 years were included in the study. Results: Out of 200 pediatric skin disorders, male children 138 (69%) outnumbered female children 62 (31%). The mean age of the study population was found to be 5.85±4.11 years. About 64% of the patients are from rural area and 36% are from urban. The percentage of skin disorders is allergic infections (26%), bacterial infections (23%), viral infections (11%), fungal infections (7.5%), parasitic infections (6%), autoimmune disorders (4%), and skin adnexa (2.5%). Conclusion: Our study concludes that the prevalence of allergic and bacterial skin infections was found to be common among male children from rural area

scholarly journals Skin manifestations in spondyloarthritis

2020 ◽  
Vol 12 ◽  
pp. 1759720X2097591
Author(s):  
Katharina Meier ◽  
Alexandra Schloegl ◽  
Denis Poddubnyy ◽  
Kamran Ghoreschi
Keyword(s):  
Skin Diseases ◽  
Joint Involvement ◽  
Skin Disorders ◽  
Psychosocial Burden ◽  
Cutaneous Manifestations ◽  
Skin Manifestations ◽  
Plaque Type ◽  
Interdisciplinary Field ◽  
Clinical Presentations ◽  
Physical Impact

Spondyloarthritides (SpA) like psoriatic arthritis, axial spondyloarthritis/ankylosing spondylitis, reactive arthritis and inflammatory bowel disease (IBD)-associated SpA can present with characteristic skin manifestations. These SpA-associated skin disorders may precede joint involvement, reflect a loss of efficacy of a current systemic treatment or can even be treatment associated. Cutaneous manifestations in SpA not only add additional morbidity with physical impact but also impose a psychosocial burden on affected patients. Psoriasis (PsO) – the main skin disease in SpA – has a variety of clinical presentations, including plaque-type PsO, inverse PsO, guttate PsO, erythrodermic PsO, nail PsO and pustular types. SpA associated with IBD presents with neutrophilic and granulomatous skin disorders, including pyoderma gangrenosum, hidradenitis suppurativa and cutaneous Crohn’s disease. Reactive arthritides has a favourable prognosis and may feature keratoderma blenorrhagicum or balanitis circinatum as typical skin manifestations. Immunologically, SpA-associated skin diseases share interleukin (IL)-17 and IL-23 dysregulation but show distinctive genetic and immunological profiles. Therefore, they vary in their treatment responses to targeted therapies with biologicals or small molecules. In this review, we highlight the clinical presentation of skin manifestations in SpA and discuss therapeutic approaches in this interdisciplinary field.

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