scholarly journals HPV-associated lesions in the Russian Federation: assessment of the problem

2019 ◽  
Vol 21 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Nikolay I Briko ◽  
Platon D Lopukhov ◽  
Andrei D Kaprin ◽  
Elena G Novikova ◽  
Olga I Trushina ◽  
...  

Aim. To estimate the prevalence and trends of the long-term dynamics of morbidity and mortality associated with various manifestations of HPV infection in Russia in recent years. Materials and methods. We analyzed retrospective data with diagnostic codes related to cervical cancer, penile cancer, anal canal cancer, head and neck cancer (including the oral cavity, oropharynx, larynx and larynx), anogenital (venereal) warts from the official statistic of cancer register and STIs using incidence and mortality rates in Russia between January 2007 and December 2016 and retrospective data with diagnostic codes related to cancer of the vulva and cancer of the vagina between January 2011 and December 2016. Based on the available data on the involvement of HPV in the occurrence of pathological changes, the annual generalized indices for HPV-associated neoplasms were calculated. Results. The estimated number of HPV-associated lesions in the Russian Federation for 2007-2016 amounted to 5 761 170 cases, of which 224 630 - among men and 5 536 540 - among women. The estimated number of deaths from HPV-associated cancers was 109 510 cases, of which 32 080 - among men and 77 430 - among women. The estimated incidence of HPV-associated cancers neoplasms during this period increased by 10% among the male population and by 22% among the female population, reaching 8.0 cases per 100 000 male population in 2016 and 25.2 cases per 100 thousand female population. The death rate from HPV-associated cancers did not change significantly, and in 2016 it was 4.9 cases per 100 thousand male population and 10.2 cases per 100 thousand female population. Conclusion. There is an increase in morbidity and stabilization of mortality rates from HPV-associated cancers for both female and male populations, and a decrease in the incidence of anogenital (venereal) warts.

2020 ◽  
Vol 18 (4) ◽  
pp. 58-73
Author(s):  
A.A. Kubanov ◽  
◽  
E.V. Bogdanova ◽  

Objective. To describe the dynamics of the incidence of six sexually transmitted infections among different age and gender groups of the adult population in the Russian Federation. Materials and methods. The analysis of data from the federal statistical observation of the incidence of sexually transmitted infections in the Russian Federation in 2011–2019. Results. In the Russian Federation, in all age and gender groups of the adult population during the period 2011–2019, there was a decrease in the incidence of early forms of syphilis, trichomoniasis, gonococcal and chlamydia infections. There were changes in the age structure of the number of cases of sexually transmitted infections with an increase in the proportion of cases detected among people aged 40 or over. The increase in the incidence of late and other unspecified forms of syphilis was noted among the male population aged 30 years or over and the female population aged 40 years or over. In 2019, compared to 2011, the increase in the incidence of anogenital warts and anogenital herpes virus infection was recorded among the male population aged 40 or over. Key words: age and gender groups, incidence, sexually transmitted infections, the Russian Federation


Author(s):  
Г. Л. Сафарова ◽  
В.А. Кипяткова ◽  
А. А. Сафарова

Исследование смертности занимает важное место в демографии в целом и в особенности в демографии старения. России свойственна неоднородность демографического развития, в частности региональная дифференциация показателей смертности населения. Работа посвящена анализу зависимости смертности в регионах России в старших возрастных группах от социально-экономических показателей. Исследование проводили с использованием методов регрессионного анализа, где в качестве единиц наблюдения выступали субъекты РФ, в качестве объясняемой переменной - смертность мужского (женского) населения старшего (60+) возраста, представленная в виде стандартизованных по структуре населения коэффициентов. В результате работы выявлены значимые социально-экономические факторы, позволяющие объяснить различия уровней смертности в субъектах РФ. Studies of old-age mortality are an important part of demography, especially the demography of ageing. Demographic development of Russia is characterized by heterogeneity including regional differences in mortality. The aim of the paper is to analyze the dependence of mortality at old-age groups on socio-economic indicators. The study is conducted using methods of regression analysis; the units of observation are the regions of the Russian Federation, the explained variable is the mortality rate of male (female) population at older (60+) ages standardized by the population-age structure. As a result, the significant socio-economic factors, explaining the differences of mortality rates in the regions of the Russian Federation, were identified.


2021 ◽  
Author(s):  
Vakhtang M. Merabishvili

Malignant neoplasms (MNO) of esophagus is the localization with a high mortality rate. Years of searching for effective treatment in Russia have resulted in modest success. The median survival rate of patients is expressed in months, 70% of patients die in the first year of dispensary registration, the levels of one-year mortality rates for men and women practically do not differ. The esophageal cancer (EC) morbidity and mortality rates have slightly decreased in 20002018 in Russia and has declined only among the male population of the Northwestern Federal District. Aim of the study. To study the trends in the morbidity and mortality rates in the population of Russia and the Northwestern Federal District of the Russian Federation. Qualitative analytical indicators, such as the accuracy index and the year-to-year mortality patterns in esophageal cancer patients, will be further considered. Results of the study. The highest standardized EC morbidity rates of the population were found in Zimbabwe (Harare, Africans) 15.5 0/0000, Japan (Miyage) 14.3 0/0000 and the Arkhangelsk region of Russia 12.8 0/0000. In 2000-2019 the level of standardized morbidity rates of the Russian population with EC has decreased from 3.44 to 3.19 0/0000 or 7.3% (both sexes), mortality rates from 3.32 to 2.66 0/0000, or 19.9%. A decrease in the morbidity and mortality rates from EC occurred in the Northwestern Federal District of the Russian Federation, only among the male population. Annual EC mortality rate mainly occurs according to the classical model. The highest level is determined in the first year of follow-up (72-74%); by the end of the decade, only 4.1% of patients remain from those initially recorded. The accuracy index has decreased in Russia and in the Northwestern Federal District of the Russian Federation, respectively, to 0.84 and 0.86 (both sexes) but has remained above the critical mark of 0.7 for localizations with a high mortality rate.


2018 ◽  
pp. 161-165 ◽  
Author(s):  
N. P. Malishevskaya ◽  
A. V. Sokolova ◽  
L. V. Demidov

Over the past 40 years, the incidence of skin melanoma in the world has increased approximately 3-fold.To study the current epidemiological situation of skin melanoma in the Russian Federation, data on the absolute, coarse and standardized incidence rates of melanoma (S43) in the male and female populations were analyzed. The specific gravity of the melanoma patients detected actively was analyzed at different stages of the tumor process who died within the first year since the diagnosis was established between 2006–2016.The incidence of skin melanoma in the Russian population is characterized by a constant increase of indexes, the average annual rate of increase in the incidence of the Russian Federation’s population of melanoma is 2 times higher than that of the general oncological morbidity. A higher average annual rate and a general increase in the incidence of SM is recorded in the male population. Only every 4th patient in the RF is detected actively, despite the fact that melanoma is a tumor of visual localization. In general, only one third of patients with skin melanoma (32.8%) are diagnosed in the first stage of the tumor process in the Russian Federation. Over the period from 2006 to 2016 in Russia, the indicators of neglect on skin melanoma significantly decreased by 40.6%, however they remain at an unacceptably high level. The index of the first-year lethality from skin melanoma in Russia for the period from 2006 to 2016 decreased by 26.01%.To improve the index of active detection of patients with SM, especially in the early stages, it is necessary to create a system for interaction of primary contact physicians with the patient (dermatovenerologists, cosmetologists, therapists) with the oncological service, the formation of on-alertness among physicians of all specialties, and among the population.


2019 ◽  
Vol 15 (5) ◽  
pp. 612-621
Author(s):  
S. A. Shalnova ◽  
M. V. Ezhov ◽  
V. A. Metelskaya ◽  
S. E. Evstifeeva ◽  
V. I. Tarasov ◽  
...  

Experimental and clinical data indicate a significant contribution of lipoprotein(a) (Lp[a]) to the atherogenesis. However, the pathophysiological mechanisms of this relationship are not fully understood.Aim. To investigate the distribution of Lp(a) in the population of the regions participating in the Study “Epidemiology of Cardiovascular Diseases in the Regions of the Russian Federation” (ESSE-RF) and to evaluate its associations with cardiovascular risk factors.Material and methods. Representative samples of the male and female population of 7 regions of the Russian Federation, aged from 25 to 64 years, enrolled in the multi-center cross-sectional epidemiological study were analyzed. A total of 10332 people were examined, of whom 3732 were men (36.0%) and 6600 were women (64.0%), the average age was equal in both sexes.Results. The mean value of Lp(a) reached 22.4 mg/dl (standard deviation 21.3 mg/dl) and significantly differed from the median (11.1 mg/dl; interquartile range from 3.9 to 20.2 mg/dl), forming the right-skewed distribution in both male and female population. Lp(a) levels were statistically significantly correlated with the level of low-density lipoproteins cholesterol (LDL-C), ароВ/аpoAI and total cholesterol. Notably, the odds ratios were growing by quintiles, and increased along with increasing lipid values (p<0.0001). Lp(a) levels were also positively associated with high-sensitivity C-reactive protein (hs-CRP) and negatively correlated with blood concentration of glucose and triglycerides (TG). There were no associations with body mass index, waist circumference and smoking status.Conclusion. According to the ESSE-RF data, there are significant positive associations of Lp(a) with the LDL-C level, the ароВ/аpoAI ratio, total cholesterol, and hs-CRP. Negative associations are established with glucose and TG levels. The future studies should be planned with the notion of the Lp(a)’s right-skewed distribution type. 


2021 ◽  
Vol 31 (5) ◽  
pp. 551-561
Author(s):  
Elena V. Bystritskaya ◽  
Tatiana N. Bilichenko

Respiratory diseases (RD) represent one of the most urgent issues in Russian health care and have high socio-economic significance.The aim. To study the dynamics of total morbidity and mortality in the Russian Federation, as well as the mortality associated with RD in the working-age population in 2015 – 2019.Methods. The official statistical data of the Ministry of Health of the Russian Federation and the Federal State Statistics Service were analyzed.Results. In 2019, the total RD-associated morbidity increased by 5.4%, and the prevalence of pneumonia increased by 29.0% compared to 2015. In 5 federal districts (FD), the morbidity exceeded the average Russian morbidity in 2019 (40,694.7). The maximum level was observed in the North-Western FD (50,224.1). The prevalence of pneumonia (Russia – 524.4) in 4 FDs exceeded the average Russian prevalence. The maximum level was reported in the Far Eastern FD (749.2 cases per 100 thousand of the total population). The RD-associated mortality rate in Russia was 51.8 cases per 100 thousand in 2015 and 41.6 cases per 100 thousand in 2018 (–19.7%). In 2018, the highest RD-associated mortality was observed in the Siberian FD (68.0) and Far Eastern FD (57.8 per 100 thousand people). From January to December 2019, the highest mortality associated with pneumonia in the working-age population was observed in the Far Eastern FD (28.2 per 100 thousand people). The RD-associated mortality rate in the male population was 4.2 times higher than in the female population (26.7 and 6.3, respectively, per 100 thousand persons of matching age).Conclusion. The highest morbidity was found in 2018 and 2019 in the Northwestern FD and Far Eastern FD. The RD-associated mortality in the Siberian FD and Far Eastern FD exceeded the average Russian values. This last observation requires additional research to improve the quality of medical care.


2014 ◽  
Vol 15 (5) ◽  
pp. 2201-2204 ◽  
Author(s):  
Svetlana Nikolaevna Gyrylova ◽  
Mariya Borisovna Aksenenko ◽  
Dmitriy Vladimirovich Gavrilyuk ◽  
Nadezda Vladimirovna Palkina ◽  
Yuriy Alexandrovich Dyhno ◽  
...  

2008 ◽  
Vol 7 (1) ◽  
pp. 119-123
Author(s):  
T. G. Ruksha ◽  
A. Ye. Dettsel ◽  
A. B. Salmina ◽  
Ye. I. Taksanova ◽  
K. A. Dettsel

Skin cancer is one of the most common malignancies and its increasing rates are found all over the world and in the Russian Federation in particular. The paper presents statistical analysis of the data on skin cancer morbidity and mortality rates in Krasnoyarsk Region summarized for the period since 1999 until 2005. Peculiarities of occurrence of this pathology among male and female persons are evaluated, tendencies of epidemiology of these tumors are analyzed, and comparative analysis of skin cancer morbidity in Krasnoyarsk Region with the Russian Federation as a whole and with foreign countries is carried out.


2019 ◽  
Vol 12 (2) ◽  
pp. 6-18
Author(s):  
A. A. Tkachenko

The subject of the research is the goals and targets of the Demography national project and related national and federal projects aiming to resolve the problems of the socio-demographic development of Russia, primarily, elimination or at least reduction of poverty of a significant part of the country’s population. The purposes of the research were to identify and substantiate ways to solve socio-demographic problems defined in the national project, and estimate the scope of its financing planned by the Russian Federation Government. The paper proves that until now the lack of sufficient livelihood is monitored in Russia only by the absolute income poverty index, which makes it impossible to compare the poverty dynamics correctly in both time and space. The paper focuses on national projects aimed at increasing the human capital based on long-term forecasts of indicators to be achieved. It might happen that the planned significant contribution of the Russian Federation regions to the Healthcare national project will hamper the effective implementation of the Demography national project due to the lack of regional funds. It is proposed that reports on poverty reduction are submitted annually to the UNICEF to inform this international organization on measures taken to achieve the goal of twofold poverty reduction, particularly measures to ensure safe, healthy and happy childhood, in order to be aware of the poverty reduction progress. The issue of increasing life expectancy cannot be solved without taking measures specific for the male and female population. Therefore, the target statistics indicator ignoring the gender differences cannot be correct in respect of the entire population. It is concluded that if the national projects aimed at the human capital development have been implemented successfully the Russian socio-demographic policy will contribute to the growth of the economy.


Sign in / Sign up

Export Citation Format

Share Document