The state of cancer care in Russia: esophageal cancer (morbidity, mortality, reliability of accounting, typical mortality). Population-based research at the federal district level. Part I.

2021 ◽  
Author(s):  
Vakhtang M. Merabishvili
Keyword(s):  
Esophageal Cancer ◽  
Mortality Rate ◽  
Russian Federation ◽  
Federal District ◽  
Mortality Rates ◽  
Morbidity And Mortality ◽  
First Year ◽  
Male Population ◽  
Accuracy Index ◽  
The Russian Federation

Malignant neoplasms (MNO) of esophagus is the localization with a high mortality rate. Years of searching for effective treatment in Russia have resulted in modest success. The median survival rate of patients is expressed in months, 70% of patients die in the first year of dispensary registration, the levels of one-year mortality rates for men and women practically do not differ. The esophageal cancer (EC) morbidity and mortality rates have slightly decreased in 20002018 in Russia and has declined only among the male population of the Northwestern Federal District. Aim of the study. To study the trends in the morbidity and mortality rates in the population of Russia and the Northwestern Federal District of the Russian Federation. Qualitative analytical indicators, such as the accuracy index and the year-to-year mortality patterns in esophageal cancer patients, will be further considered. Results of the study. The highest standardized EC morbidity rates of the population were found in Zimbabwe (Harare, Africans) 15.5 0/0000, Japan (Miyage) 14.3 0/0000 and the Arkhangelsk region of Russia 12.8 0/0000. In 2000-2019 the level of standardized morbidity rates of the Russian population with EC has decreased from 3.44 to 3.19 0/0000 or 7.3% (both sexes), mortality rates from 3.32 to 2.66 0/0000, or 19.9%. A decrease in the morbidity and mortality rates from EC occurred in the Northwestern Federal District of the Russian Federation, only among the male population. Annual EC mortality rate mainly occurs according to the classical model. The highest level is determined in the first year of follow-up (72-74%); by the end of the decade, only 4.1% of patients remain from those initially recorded. The accuracy index has decreased in Russia and in the Northwestern Federal District of the Russian Federation, respectively, to 0.84 and 0.86 (both sexes) but has remained above the critical mark of 0.7 for localizations with a high mortality rate.

State of the Russian Oncology Service: esophageal cancer, median survival, observed and relative survival of patients considering disease stage and histological structure of tumors (population-based study at the federal district level). Part 2

2021 ◽  
Author(s):  
Vakhtang M. Merabishvili
Keyword(s):  
Esophageal Cancer ◽  
Survival Rate ◽  
Russian Federation ◽  
Federal District ◽  
Population Based ◽  
First Year ◽  
The Past ◽  
The Russian Federation ◽  
One Year ◽  
First Time

Esophageal cancer (EC) is the most severe pathology of malignant tumors, with the mortality rate of patients exceeding 70% in the first year of observation. Over the past 19 years, there was a slight improvement in the effectiveness of anticancer measures for this localization of tumors. In February 2019 the Population-based Cancer Registry database (PCRD) of the Northwestern Federal District of the Russian Federation (NWFD RF) was developed with more than 1 million 350 thousand observations which provides insight into ​​the real state of the effectiveness of anti-cancer measures and directs the following development of the database. After a thorough data quality assurance, about 1 million observations were selected for analysis. From 2000 to 2018, 15760 primary EC cases were accumulated in the NWFD RF PCRD. Considering that the levels of standardized morbidity and mortality rates of the population of Russia and the Northwestern Federal District of the Russian Federation are close in terms of the level of indicators, we believe that the data obtained for the first time in Russia on the survival of EC patients in the Northwestern Federal District of the Russian Federation fully reflect the state of the effectiveness of combating EC in Russia. The purpose of the study is to carry out a set of analytical calculations of the survival rates of EC patients in the dynamics over the past 19 years according to the NWFD RF PCRD. All calculations were performed in accordance with the international requirements for such development and, first of all, according to Eurocare standards. The results of our study indicate that the EC median survival rate for both sexes has increased from 5 to 6 months. The mortality rate of patients in the first year of follow-up has decreased from 72.4 to 71.4% (both sexes), from 73.9 to 71.6% among men, from 69.3 to 65.1% among women. The five-year survival rate of EC patients in the NWFD RF had slight fluctuations, especially among the female population. Data grouped by five years for three five-year observation cycles has shown an increase in the five-year survival rate of EC patients from 7.3 to 8.1%, and the one-year survival rate has increased over four five-year cycles from 25.3 to 30.8%. For the first time in Russia, at the population level, the effect of treating EC patients has been shown according to the fourth sign of ICD-10. The greatest treatment success has been achieved for EC patients under the following rubrics: Cervical esophagus (C15.0) from 23.3 to 35.0% (one-year survival), Thoracic esophagus (C15.1) from 29.6 to 35.8% and especially significant improvements have been made for patients with the Upper third of esophagus (C15.3) from 18.2 to 34.0%. It is important to note that over the four observation periods, the proportion of EC patients under C15.9 rubric Esophagus, unspecified has decreased from 29.3 to 19.8%, which indicates a significant improvement in the quality of diagnosis.

scholarly journals MORBIDITY AND MORTALITY RATE FROM MALIGNANT TUMORS IN CHILDREN IN THE RUSSIAN FEDERATION OVER 2011-2016

2017 ◽  
Vol 22 (6) ◽  
pp. 322-328 ◽  
Author(s):  
Maxim Yu. Rykov
Keyword(s):  
Mortality Rate ◽  
Medical Care ◽  
Russian Federation ◽  
Mortality Rates ◽  
Diagnostic Methods ◽  
Morbidity And Mortality ◽  
Oncological Diseases ◽  
The Russian Federation ◽  
One Year ◽  
The One

Introduction Planning the medical care management for cancer children is based, inter alia, on epidemiological data: morbidity and mortality rates in children with malignant neoplasms. Material and methods. The data of the public health care executive authorities of the constituent entities of the Russian Federation have been analyzed. These reports included data on morbidity, mortality, one-year mortality rates, and the period of the medical care delivery for children with oncological diseases in subjects. Results. Over past 6 years, the number of primary patients, identified annually (by 2011 - 3230, 2016 - 3875) increased by 20%; the number of patients under observation was increased by 34.8% (2011 - 17,958, 2016 - 24,207). The incidence increased by 9.8%: from 12.2 per 100,000 (0-17 years) in 2011 to 13.4 in 2016. The standardized mortality rate in 2011-2013 was 4 (per 100 thousand. 0-19 years), in 2014-2016 - 3.6 (per 100 thousand. 0-17 years). The one-year mortality rate decreased by 2%: from 10.8% in 2011 to 8.8% in 2016, the number of actively identified patients increased by 1.4% (in 2007 - 3.8%, in 2016 - 5.2%), the one-year mortality rate decreased by 5.9% (2007 - 14.7%, 2016 - 8.8%). Among causes of death the first place was occupied by leukemia, the second one - by tumors of the brain and spinal cord, the third - sarcomas of soft tissues. Conclusion. The noted dynamics demonstrates an increase in the detectability of oncological diseases in children, therefore, it indicates to the improvement of diagnostic methods. Taking into consideration the average world morbidity rate to account of 15 per 100 thousand children, it is possible to forecast a further increase in the incidence (detectability) of up to 4 500 primary patients by 2022. Thus, at present, an annual underreport is about 700(16%) patients. A low percentage of actively identified children shows the insufficient training of primary care physicians (district pediatricians) in pediatric oncology.

scholarly journals The incidence of skin melanoma in the Russian Federation and federal districts

2018 ◽  
pp. 161-165 ◽  
Author(s):  
N. P. Malishevskaya ◽  
A. V. Sokolova ◽  
L. V. Demidov
Keyword(s):  
Russian Federation ◽  
Incidence Rates ◽  
Annual Rate ◽  
First Year ◽  
Visual Localization ◽  
Skin Melanoma ◽  
Average Annual Rate ◽  
Male Population ◽  
Rate Of Increase ◽  
The Russian Federation

Over the past 40 years, the incidence of skin melanoma in the world has increased approximately 3-fold.To study the current epidemiological situation of skin melanoma in the Russian Federation, data on the absolute, coarse and standardized incidence rates of melanoma (S43) in the male and female populations were analyzed. The specific gravity of the melanoma patients detected actively was analyzed at different stages of the tumor process who died within the first year since the diagnosis was established between 2006–2016.The incidence of skin melanoma in the Russian population is characterized by a constant increase of indexes, the average annual rate of increase in the incidence of the Russian Federation’s population of melanoma is 2 times higher than that of the general oncological morbidity. A higher average annual rate and a general increase in the incidence of SM is recorded in the male population. Only every 4th patient in the RF is detected actively, despite the fact that melanoma is a tumor of visual localization. In general, only one third of patients with skin melanoma (32.8%) are diagnosed in the first stage of the tumor process in the Russian Federation. Over the period from 2006 to 2016 in Russia, the indicators of neglect on skin melanoma significantly decreased by 40.6%, however they remain at an unacceptably high level. The index of the first-year lethality from skin melanoma in Russia for the period from 2006 to 2016 decreased by 26.01%.To improve the index of active detection of patients with SM, especially in the early stages, it is necessary to create a system for interaction of primary contact physicians with the patient (dermatovenerologists, cosmetologists, therapists) with the oncological service, the formation of on-alertness among physicians of all specialties, and among the population.

scholarly journals Lung cancer (C33, 34). Morbidity, mortality, accuracy of registration, localization and histological structure (population study)

2021 ◽  
Vol 67 (3) ◽  
pp. 361-367
Author(s):  
Vakhtang Merabishvili ◽  
Iuliia Iurkova ◽  
Aleksandr Shcherbakov ◽  
Evgenii Levchenko ◽  
Anton Barchuk ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Russian Federation ◽  
Federal District ◽  
Developed Countries ◽  
First Year ◽  
Histological Structure ◽  
The Real ◽  
Real Value ◽  
The Russian Federation ◽  
First Time

Lung cancer (LC) is the main cause of morbidity and mortality in the population of Russia and many economically developed countries of the world. At the same time, referring to localizations with a high mortality rate, the official data on the number of recorded primary cases (which form the incidence rate) are significantly underestimated, which is confirmed by the registration reliability index, which in many territories is higher than critical values. The aim of our study is to present the real state of the prevalence of PC in Russia, based on the newly created database (DB) of the population cancer register (PRR) of the Northwestern Federal District of the Russian Federation (NWFD RF) — the only one in Russia. We analyzed the loss of the number of primary patients who were not included in the state reporting, showed the real value of the achieved death rate of patients in the first year of dispensary observation, calculated the patterns of annual mortality of patients, the median of survival and 1 and 5-year survival of patients with lung cancer based on the database of the population cancer registry. Northwestern Federal District of the Russian Federation, on the materials of which for the first time in Russia the dynamics of changes in the detailed localization and histological structure of lung cancer was traced.

scholarly journals The state of cancer care in Russia: lung cancer, patient survival (population study at the federal district level)

2021 ◽  
Vol 67 (4) ◽  
pp. 492-500
Author(s):  
Vakhtang Merabishvili ◽  
Iuliia Iurkova ◽  
Evgenii Levchenko ◽  
Aleksandr Shcherbakov ◽  
Nikolai Krotov
Keyword(s):  
Lung Cancer ◽  
Mortality Rate ◽  
Relative Survival ◽  
Federal District ◽  
Developed Countries ◽  
Morbidity And Mortality ◽  
Malignant Neoplasms ◽  
Male Population ◽  
Female Population ◽  
One Year

Lung cancer (LC) remains the main cause of morbidity and mortality in many economically developed countries of the world. In 2019, more than 60 thousand primary cases of LC and more than 50 thousand deaths from this cause were recorded in Russia. The registration reliability index remains high - 0.83, which indicates a significant underestimation of primary patients.At the same time, it should be noted that the standardized rates of morbidity and mortality from LC continue to decline. The most effective criterion for evaluating the activity of the oncological service is the indicator of the observed and relative survival of patients with malignant neoplasms (MNO). Such a possibility exists in many territories of Russia, but it is calculated only in selected territories working according to our programs, and first of all, in the newly created population cancer register of the Northwestern Federal District (NWFD) with a database (DB) of more than 1 million. 350 thousand observations.The results obtained can be fully extended to the whole of Russia, since the levels of standardized indicators of morbidity and mortality from LC in Russia and the NWFD of the Russian Federation are practically identical.The study showed that from 2000 to 2017, the median survival rate of patients with LC in the NWFD increased from 6.4 to 8.0 months, and the one-year mortality rate decreased from 65,2% to 60,8%.The change in indicators is extremely slow. Differences in the mortality rate (in standardized indicators) from LC between men and women differ in Russia by 7,1, in the NWFD of the RF - by 7.0.Mortality in men from LC in the first year of observation is 63.5% versus 52.5% among the female population, which is primarily due to the peculiarities of the industrial production process and bad habits that are more characteristic of the male population.

scholarly journals Medical care for children with cancer in the Siberian Federal District

2019 ◽  
Vol 18 (1) ◽  
pp. 5-12
Author(s):  
M. Yu. Rykov
Keyword(s):  
Mortality Rate ◽  
Medical Care ◽  
Russian Federation ◽  
Federal District ◽  
Siberian Federal District ◽  
Children With Cancer ◽  
Aim Analysis ◽  
Incidence And Mortality ◽  
Hospital Beds ◽  
The Russian Federation

background. The analysis of the quality of medical care for children with cancer is based on statistical data. Evaluation of the results obtained is also the basis of the strategy for the development of medical care for this category of patients. aim: analysis of the main parameters characterizing medical care for children with cancer in the Siberian Federal District. material and methods. The reports for 2017 on the health protection of 11/12 (91.6 %) constituent entities of the Russian Federation belonging to the Siberian Federal District were analyzed (Irkutsk Region did not provide data). results. In 2017 the number of children aged 0–17 years was 3 722 470, the number of pediatric hospital beds for children with cancer (ages 0–17 years) was 260 (0,7 per 10,000), and the average number of bed-days per year was 342.2. In 3 (25 %) constituent entities of the Russian Federation, there were no departments of pediatric oncology and in 1 (8,3 %) there were no hospital beds for children with cancer. The number of physicians, who specialized in children’s cancer was 49, of them 32 (65,3 %, 0,08 per 10,000, ages 0–17 years) had a certificate of a pediatric oncologist. In 1 (8,3 %) constituent entity of the Russian Federation, there were no pediatric oncologists. For children aged 0–17 years, the cancer incidence rate was 11.7 per 100,000 children, the cancer mortality rate was 2,2 per 100,000, and one-year mortality rate was 7,4 %. 188 (43,2 %) primary cancer patients were referred to medical institutions of the Federal District, and 17 (3,9 %) primary patients left the territory of the Russian Federation. conclusion. The low incidence and mortality rates can be explained by the lost of reliable follow-up data. It is advisable to introduce electronic health record systems. For reliable estimation of hospital bed supply for children with cancer and percent of patients referred to medical centers for treatment, it is necessary to carry out a clinical audit. Deficiency of pediatric oncologists should be eliminated by reforming the training of medical personnel.

scholarly journals HPV-associated lesions in the Russian Federation: assessment of the problem

2019 ◽  
Vol 21 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Nikolay I Briko ◽  
Platon D Lopukhov ◽  
Andrei D Kaprin ◽  
Elena G Novikova ◽  
Olga I Trushina ◽  
...  
Keyword(s):  
Russian Federation ◽  
Mortality Rates ◽  
Retrospective Data ◽  
Anal Canal Cancer ◽  
Male Population ◽  
Female Population ◽  
Diagnostic Codes ◽  
Associated Lesions ◽  
The Russian Federation ◽  
Venereal Warts

Aim. To estimate the prevalence and trends of the long-term dynamics of morbidity and mortality associated with various manifestations of HPV infection in Russia in recent years. Materials and methods. We analyzed retrospective data with diagnostic codes related to cervical cancer, penile cancer, anal canal cancer, head and neck cancer (including the oral cavity, oropharynx, larynx and larynx), anogenital (venereal) warts from the official statistic of cancer register and STIs using incidence and mortality rates in Russia between January 2007 and December 2016 and retrospective data with diagnostic codes related to cancer of the vulva and cancer of the vagina between January 2011 and December 2016. Based on the available data on the involvement of HPV in the occurrence of pathological changes, the annual generalized indices for HPV-associated neoplasms were calculated. Results. The estimated number of HPV-associated lesions in the Russian Federation for 2007-2016 amounted to 5 761 170 cases, of which 224 630 - among men and 5 536 540 - among women. The estimated number of deaths from HPV-associated cancers was 109 510 cases, of which 32 080 - among men and 77 430 - among women. The estimated incidence of HPV-associated cancers neoplasms during this period increased by 10% among the male population and by 22% among the female population, reaching 8.0 cases per 100 000 male population in 2016 and 25.2 cases per 100 thousand female population. The death rate from HPV-associated cancers did not change significantly, and in 2016 it was 4.9 cases per 100 thousand male population and 10.2 cases per 100 thousand female population. Conclusion. There is an increase in morbidity and stabilization of mortality rates from HPV-associated cancers for both female and male populations, and a decrease in the incidence of anogenital (venereal) warts.

scholarly journals Morbidence of pregnant anemia and its impact on infant mortality

2019 ◽  
Vol 10 (1) ◽  
pp. 43-48
Author(s):  
Dmitry O. Ivanov ◽  
Vadim K. Iurev ◽  
Kseniia G. Shevtsova ◽  
Karina E. Moiseeva ◽  
Shalva D. Kharbedia ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Infant Mortality ◽  
Pregnant Women ◽  
Russian Federation ◽  
Federal District ◽  
Infant Mortality Rate ◽  
Successful Outcome ◽  
North West ◽  
The North ◽  
The Russian Federation

An important role in the normal development of the fetus and the successful outcome of pregnancy is played by the state of health of pregnant women. One of the significant factors of perinatal risk is anemia of pregnant women. In order to assess the level and dynamics of the incidence of anemia in pregnant women, official statistical reports and publications of the Federal State Statistics Service for 2005-2017 and Central Research Institute for Organization and Informatization of Health of the Ministry of Health of the Russian Federation for 2012-2018 were analyzed. Using a trend analysis using a trend method, a prognosis was made for the incidence of anemia in pregnant women up to 2021 in the Russian Federation as a whole and separately in the North-West Federal District. In order to assess the impact of the predictor “anemia of pregnant women” on the infant mortality rate, data from primary medical documentation was copied to 250 children who died before the age of 1 year in the North-West Federal District. It has been established that the incidence of anemia in pregnant women in the North-West Federal District significantly exceeds the average level in the Russian Federation. Provided that factors affecting the course of pregnancy remain unchanged, the incidence of anemia in pregnant women by 2021 on average in the Russian Federation will decrease to 32.2% of the number of women who have completed pregnancy, and in the North-West Federal District will increase to 37.5%. During pregnancy, the incidence of anemia in women whose child died before the age of 1 year in the North-West Federal District amounted to 44.16 ± 0.39% of the number of women who completed the pregnancy, which significantly exceeded the average figure in the district, which in 2017 was equal to 35.90 ± 0.35% (p < 0.05). A direct correlation has been established between the predictor “anemia in pregnant women” and the infant mortality rate.

scholarly journals The analysis of high cardiovascular morbidity and mortality in the adult population as a medical and social problem and the search for ways to solve it

2021 ◽  
Vol 20 (1) ◽  
pp. 58-64
Author(s):  
V. P. Kosolapov ◽  
M. V. Yarmonova
Keyword(s):  
Mortality Rate ◽  
Russian Federation ◽  
Social Problem ◽  
Adult Population ◽  
Cardiovascular Morbidity ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Demographic Situation ◽  
Voronezh Region ◽  
The Russian Federation

Introduction. The article is devoted to the analysis of the state of cardiovascular morbidity (CVD), mortality of the population and the demographic situation, as well as determining the prevalence of CVD as a medical and social problem at the federal and regional levels. The analysis of the implementation of the policy of providing medical care to patients with CVD, modern scientific publications on the indicated problem, and the search for ways to solve the medical and social problem of high morbidity and mortality from CVD are carried out.Materials and methods. The data of official statistical information on the morbidity and mortality of the adult population of the Russian Federation and the Voronezh region for 2010–2019 were used, the works of modern domestic and foreign scientists dealing with the solution of this problem were studied.Results. It has been established that high CVD and mortality are an acute medical and social problem. Mortality from CVD in Russia in 2019 amount to 46.8% of the total number of deaths. The mortality rate from CVD in Russia exceeds that in the developed countries of the European Union. Despite the presence of positive trends in the fight against this disease, the mortality rate from CVD in the Voronezh region is higher than the average for the Russian Federation (601.8 and 573.2 per 100 thousand population, respectively). The deterioration of the demographic situation, the presence of active targeted projects in this area are the basis for conducting scientific research to find ways to duce CVD and mortality in the adult population.Conclusion. The high morbidity and mortality from CVD requires a search for new ways to solve the problem, since the existing approaches to its solution are not holistic and universal. It is urgent to develop an integrated approach that takes into account the medical and social characteristics of the adult population of the region.

scholarly journals Impact of the COVID-19 pandemic on mortality dynamics in the Far Eastern Federal District

2021 ◽  
pp. 8-20
Author(s):  
V. P. Kolosov ◽  
L. G. Manakov ◽  
E. V. Polyanskaya ◽  
J. M. Perelman
Keyword(s):  
Mortality Rate ◽  
Respiratory Diseases ◽  
Causes Of Death ◽  
Federal District ◽  
Mortality Rates ◽  
First Year ◽  
Entire Spectrum ◽  
Icd 10 ◽  
Demographic Processes ◽  
Far Eastern

Introduction. New viral respiratory infections in humans make it possible to speak of corona viruses as extremely dangerous human pathogens. They are characterized by a high mortality rate and pose a significant medical and social threat to society due to life-threatening complications of the disease. In this regard, it seems necessary to answer the questions about the dynamics of mortality of the population of the region for different classes of ICD-10 in the prepandemic and pandemic period, including various nosological forms of respiratory diseases. Aim. To assess the degree of influence of the pandemic of the new respiratory coronavirus infection COVID-19 on the mortality rate of the population for various classes of ICD-10, including the class “Diseases of the respiratory system” in the Far Eastern Federal District.Materials and methods. To implement the tasks of the study, a complex of analytical, epidemiological and statistical studies was carried out. Methods used: descriptive statistics, epidemiological analysis and monitoring; mathematical; structural and comparative analysis, methods of time series analysis and content analysis of publications on the problem. Epidemiological and statistical assessment of mortality was carried out on the basis of ICD-10 using the database of the Federal State Statistics Service for 1999-2020 in the territory of the Far Eastern Federal District. For the analysis and processing of statistical information, modern information systems and computer programs (MS Excel-2016) were used. Results. The pandemic of COVID-19 has had a significant impact on the level and structure of mortality across the entire spectrum of the main causes of death, and its magnitude (98.8 per 100,000, 2020), as a new cause of death, exceeds the whole the class of causes of death ICD-10 (J00-J99) by 33.3%, changing the pace and direction of demographic processes in Russia. At the same time, the dynamics of mortality due to respiratory diseases is unprecedented, the level of which in the Russian Federation in the first year of the COVID-19 pandemic increased by 38.8%, and in the Far Eastern Federal District – by 27.7% against the background of the previous long-term stable a downward trend in mortality rates. Especially high growth rates of mortality rates are observed in pneumonia, the level of which has increased by 3.5 times over the last decade, and among city residents – by 4.2 times (Amur Region). Features of the socio-economic and natural-climatic living conditions of the population of the region determine a significant differentiation of regions in terms of mortality rates, including due to respiratory diseases, the gradients of which among the subjects of the Far Eastern Federal District in the first year of the pandemic period (2020) amounted to 2.5 times with a minimum the level in the Republic of Sakha (Yakutia) (40.9 per 100,000 population) and the maximum – in the Jewish Autonomous Region (101.7 per 100,000 population), which indicates the ambiguous degree of influence of the new viral infection on the dynamics of mortality. At the same time, the variability in mortality rates due to respiratory diseases in the previous period (1999-2019) was even more pronounced, and among the subjects of the Far Eastern Federal District, during this period, higher mortality rates were also demonstrated, which are not even comparable to the current level of the pandemic period. These circumstances require a detailed study and a substantive analysis of the degree of influence of a COVID-19 on the mortality rate of the population using mechanisms and methods for its detection, record and registration. Conclusion. The pandemic of COVID19 had a significant impact on the level and structure of mortality across the entire spectrum of major causes of death, especially in the ICD-10 class “Respiratory diseases”, changing the pace and direction of demographic processes.

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