scholarly journals Association between Fever during Admission and Outcome of Treatment in Tuberculous Meningitis Patients in Hasan Sadikin General Hospital Bandung

2019 ◽  
Vol 2 (3) ◽  
Author(s):  
Regita A Kuswanto ◽  
Ahmad Rizal ◽  
R Raspati C Koesoemadinata

Tuberculous meningitis (TBM) is the most common type of meningitis with a highmortality rate (20-41%). There are limited data on factors associated with outcome oftreatment, especially in Indonesia. Fever is a common inflammatory process in meningitispatients. This study aims to investigate the association between fever during admission andoutcome of treatment in TBM patients treated in the In-patient Neurology Department at HasanSadikin Hospital Bandung. This is an observational retrospective cohort study conducted byusing medical records from 2017. The inclusion criteria of this study were all medical recordsof inpatients who were diagnosed as TBM and ?18 years old, while the exclusion criteria wereincomplete medical records. The variables in this study were age, gender, body temperature,classification of TBM, and Glasglow Outcome Scale (GOS). There were 125 medical recordswhich fulfilled the inclusion criteria. Kruskal- Wallis test showed that fever was notsignificantly associated with GOS (p=0.193). In conclusion, fever during admission was notassociated with GOS in TBM patients.Keywords: tuberculous meningitis, fever, Glasglow Outcome Scale, outcome

2020 ◽  
Vol 4 (1) ◽  
pp. 87-94
Author(s):  
Frita Dwi Luhuria ◽  
Defrin Defrin ◽  
Andi Friadi

The Risk Malignancy Index (RMI) is one of the simplest assessments that can assist in diagnosing and determining the prognosis of benign and malignant adnexa masses. Epithelial carcinoma is the most common type of about 90% of ovarian cancers.  As many as 35-40% of the epithelial type are serous and 6-10% are musinosum.This study aims to compare the picture of RMI value on the incidence of ovarian cancer serosum and musinosum type. This study was cross sectinal comparative study from medical records of ovarian cancer patients at obstetrics and gynecology section in DR M Djamil Hospital Padang from January 1st, 2017 until December 31st, 2017. The population was found one hundred and forty of patients with ovarian cancer and only one hundred and twenty nine of patients met the inclusion criteria and there were no exclusion criteria. Next RMI value is calculated based on RMI 1 formula, result is described in tabular form and data processing with SPSS program. Conclucion of this study is there were no differences in age distribution, ascites occurrence and age of menopause in serous and musinosum ovarian cancer. There is a difference in Ca, 125 levels in serous with musinosum ovarian cancer which also contribute to the high value of RMI. The mean value of patients‘s RMI in serous type ovarian cancer is higher than the mean value of RMI in patients with type Musinosum ovarian cancer. Keywords: index of risk malignancy, menopause, ultrasonography, anatomic pathology, serous ovarian carcinoma


2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Robert J. Sanchez ◽  
Wenzhen Ge ◽  
Wenhui Wei ◽  
Manish P. Ponda ◽  
Robert S. Rosenson

Abstract Background This retrospective cohort study assessed the annualized incidence rate (IR) of acute pancreatitis (AP) in a nationally representative US adult population, as well as the variation in the risk of AP events across strata of triglyceride (TG) levels. Methods Data were obtained from IQVIA’s US Ambulatory Electronic Medical Records (EMR) database linked with its LRxDx Open Claims database. Inclusion criteria included ≥1 serum TG value during the overlapping study period of the EMR and claims databases, ≥1 claim in the 12-month baseline period, and ≥ 1 claim in the 12 months post index. All TG measurements were assigned to the highest category reached: < 2.26, ≥2.26 to ≤5.65, > 5.65 to ≤9.94, > 9.94, and > 11.29 mmol/L (< 200, ≥200 to ≤500, > 500 to ≤880, > 880, and > 1000 mg/dL, respectively). The outcome of interest was AP, defined as a hospitalization event with AP as the principal diagnosis. Results In total, 7,119,195 patients met the inclusion/exclusion criteria, of whom 4158 (0.058%) had ≥1 AP events in the prior 12 months. Most patients (83%) had TGs < 2.26 mmol/L (< 200 mg/dL), while < 1% had TGs > 9.94 mmol/L (> 880 mg/dL). Overall, the IR of AP was low (0.08%; 95% confidence internal [CI], 0.08–0.08%), but increased with increasing TGs (0.08% in TGs < 2.26 mmol/L [< 200 mg/dL] to 1.21% in TGs > 11.29 mmol/L [> 1000 mg/dL]). In patients with a prior history of AP, the IR of AP increased dramatically; patients with ≥2 AP events at baseline had an IR of 29.98% (95% CI, 25.1–34.9%). Conclusion The risk of AP increases with increasing TG strata; however, the risk increases dramatically among patients with a recent history of AP.


2002 ◽  
Vol 36 (1) ◽  
pp. 133-140 ◽  
Author(s):  
Alexander Collie ◽  
Paul Maruff

Objective: Over the past two decades, a number of systems have been developed for the classification of cognitive and behavioural abnormalities in older people, in order that individuals at high risk of developing neurodegenerative disease, particularly Alzheimer's disease, may be identified well before the disease manifests clinically. This article critically examines the inclusion and exclusion criteria of a number of such classification systems, to determine the effect that variations in criterion may have on clinical, behavioural and neuroimaging outcomes reported from older people with mild cognitive impairment. Method: Qualitative review of the literature describing systems of classifying mild cognitive impairment, and outcomes from clinical, behavioural, neuroimaging and genetic studies of older people with mild cognitive impairment. Results: The exclusion and inclusion criteria for these classification systems vary markedly, as do the design of studies upon which the validity of these systems has been assessed. Minor changes to individual exclusion/inclusion criterion may result in substantial changes to estimates of the prevalence and clinical outcome of mild cognitive impairment, while inadequate experimental design may act to confound the interpretation of results. Conclusions: As a result of these factors, accurate and consistent estimates of the outcome of mild cognitive impairments in otherwise healthy older people are yet to be obtained. On the basis of this analysis of the literature, optimal criteria via which accurate classifications of mild cognitive impairment can be made in future are proposed.


2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Aiwi Japanesa ◽  
Asril Zahari ◽  
Selfi Renita Rusjdi

AbstrakPeritonitis menjadi salah satu penyebab tersering akut abdomen yang merupakan suatu kegawatan abdomen. Peritonitis biasanya disertai dengan bakterisemia atau sepsis yang dapat menimbulkan kematian. Tujuan penelitian ini adalah untuk mengetahui hal-hal yang berkaitan dengan peritonitis agar dapat mencegah dan melakukan penanganan secepatnya terhadap kasus ini. Penelitian deskriptif retrospektif ini telah dilakukan dari September 2014 sampai Oktober 2014 dengan teknik total sampling. Data yang diambil merupakan kasus pasien peritonitis yang dirawat inap di Bagian Bedah RSUP Dr. M. Djamil Padang, kemudian dilakukan seleksi berdasarkan kriteria inklusi dan eksklusi sehingga didapatkan 98 data rekam medik periode 01 Januari 2013 sampai 31 Desember 2013.  Prevalensi peritonitis pada laki-laki (68,4%) lebih tinggi dibandingkan perempuan (31,6%). Kelompok usia terbanyak adalah 10-19 tahun (24,5%). Peritonitis sekunder umum akibat perforasi apendiks merupakan jenis peritonitis yang terbanyak (53,1%). Sebagian besar pasien peritonitis mendapatkan tatalaksana bedah berupa laparatomi eksplorasi dan apendektomi (64,3%). Lama rawatan terbanyak pada 4-7 hari (45,9%). Frekuensi pasien peritonitis menurut kondisi keluar sebagian besar dalam keadaan hidup (85,7%). Kesimpulan yang dapat diambil dari penelitian ini adalah bahwa peritonitis dapat dipengaruhi oleh faktor usia, jenis kelamin, penyebab peritonitis, tatalaksana, lama rawatan dan kondisi saat keluar dari rumah sakit.Kata kunci: peritonitis, bedah, pola AbstractPeritonitis is one of the most common cause of acute abdomen, which is an abdominal emergency. Peritonitis is usually accompanied by bacteremia or sepsis that can cause mortality. The objective of this study was to know something that associated with peritonitis in order to prevent and to respond immediately to this case. This retrospective descriptive study was conducted from September 2014 to October 2014 using a total sampling technique. Data was taken from cases of hospitalized patients with peritonitis in Surgery Ward of RSUP Dr. M. Djamil Padang, selected by on inclusion and exclusion criteria. There were 98 medical records by the period from 1st of January 2013 to 31th of December 2013. Peritonitis prevalence in men (68,4%) was higher than women (31,6%). Most common age group is 10-19 years old (24,5%). Secondary peritonitis due to perforation of the appendix is the most common type of peritonitis (53,1%). Most patients with peritonitis get a surgical procedure of exploratory laparotomy and appendectomy (64,3%). Most hospitalization length was 4-7 days (45,9%). The frequency of peritonitis patients based on conditions when discharged from hospital is mostly alive (85,7%).Conclusion from this study is that peritonitis may be influenced by age, sex, cause of peritonitis, the surgical procedure, hospitalization, and condition when discharged from hospital.Keywords: peritonitis, surgical, pattern


RMD Open ◽  
2020 ◽  
Vol 6 (2) ◽  
pp. e001340 ◽  
Author(s):  
Noemie Abisror ◽  
Yann Nguyen ◽  
Luca Marozio ◽  
Enrique Esteve Valverde ◽  
Sebastian Udry ◽  
...  

ObjectiveTo compare characteristics, pregnancies and treatments during pregnancies of seronegative and seropositive antiphospholipid syndrome (APS), to analyse factors associated with obstetrical outcome.Patients and methodsInclusion criteria were: (1) thrombotic and/or obstetrical APS (Sydney criteria); (2) absence of conventional antiphospholipid antibodies (APL); (3) at least one persistent non-conventional APL among IgA anticardiolipin antibodies, IgA anti-B2GPI, anti-vimentin G/M, anti-annexin V G/M, anti-phosphatidylethanolamine G/M and anti-phosphatidylserine/prothrombin G/M antibodies. The exclusion criteria were: (1) systemic lupus erythematosus ( SLE) or SLE-like disease; and (2) other connective tissue disease.ResultsA total of 187 women (mean 33±5 years) with seronegative APS were included from 14 centres in Austria, Spain, Italy, Slovenia and France and compared with 285 patients with seropositive APS. Seronegative APS has more obstetrical rather than thrombotic phenotypes, with only 6% of venous thrombosis in comparison to seropositive APS. Cumulative incidence of adverse obstetrical events was similar in seronegative and seropositive APS patients, although higher rates of intrauterine deaths (15% vs 5%; p=0.03), of preeclampsia (7% vs 16%, p=0.048) and lower live birth term (36±3 vs 38±3 weeks of gestation; p=0.04) were noted in seropositive APS. The cumulative incidence of adverse obstetrical events was significantly improved in treated versus untreated seronegative APS (log rank<0.05), whereas there was no difference between patients who received aspirin or aspirin-low-molecular weighted heparin combination.ConclusionSeveral non-criteria APL can be detected in patients with clinical APS features without any conventional APL, with various rates. The detection of non-criteria APL and thus the diagnosis of seronegative APS could discuss the therapeutic management similar to seropositive APS, but well-designed controlled studies are necessary.


2021 ◽  
Vol 12 ◽  
Author(s):  
Jacob Genizi ◽  
Doron Meiselles ◽  
Elisheva Arnowitz ◽  
Idan Segal ◽  
Rony Cohen ◽  
...  

Introduction: The clinical presentation of pseudotumor cerebri syndrome (PTCS) usually includes headache, nausea, and vomiting with normal physical examination apart from papilledema and diplopia. However, pseudopapilledema, which can be caused by optic nerve drusen, may lead to misdiagnosis. The prevalence of optic nerve drusen in the general population is 0.5–2%. The purpose of our study was to evaluate the prevalence and risk factors of optic nerve drusen among patients with PTCS.Materials and Methods: Medical records of children evaluated in the pediatric department at Bnai Zion Medical Center due to PTCS between 2008 and 2020 were assessed. Inclusion criteria were children age under 18 years with a PTCS diagnosis and ophthalmic B-mode ultrasonography (US). Exclusion criteria were secondary intracranial hypertension.Results: Thirty-four children were included with a mean age 10.1 years which included 50% boys. A majority of the patients, 24 (72.4%), complained of headaches, while 15 (45.5%) complained of transient visual obscuration, and 9 (26.5%) of vomiting. Visual acuity on presentation was normal (20/20–20/30) in 23 of the children (67%), moderately diminished (20/40–20/80) in 9 (26%), and showing profound loss (20/200) in 2 (7%). Five patients (14.7%) were diagnosed with optic nerve drusen via B-mode ophthalmic ultrasonography (US). However, they still fulfilled the diagnostic criteria for PTCS, and disc swelling improved after treatment. There were no statistically significant differences between the group with optic nerve drusen and the rest of the patients.Conclusions: Optic nerve drusen are common among pediatric patients with PTCS. Diagnosis of optic nerve drusen should not rule out the presence of increased intracranial pressure.


Author(s):  
Barbara Capitanio de Souza ◽  
Larissa Leci Fernandes ◽  
Debora Magalhaes Barreto ◽  
Cornelis Robert Springer

Introduction: The objectives of the study were to evaluate the prevalence of orofacial injuries in soccer players of a Brazilian club, considering the category, the position in the field, and the most affected anatomic site, through medical records. Methods: A total of 126 charts of players from the base categories (sub-15, sub-17, and sub-20) and male and female professional categories from 2016 to 2018 were evaluated. It was considered inclusion criteria to be a soccer player hired by a club in the indicated period. The exclusion criteria of the study correspond to the medical records registered after the chronological date stipulated or that did not have the correct registry of the occurred trauma. Results: The data analyzed presented a moderate value in relation to the orofacial traumas prevalence, and 64.3% of the athletes of the club have some record type of trauma in the face. We observed that soft-tissue lacerations of the lips and dental fractures present the highest frequencies (73% and 27%, respectively). The positions of defender, striker, and midfield are the most susceptible to injuries (31%, 24%, and 23%, respectively). Conclusion: Dental and orofacial trauma are a problem commonly encountered in sports, being present also in collective sports, such as football. It was observed a moderate prevalence of injuries on the face, especially among the athletes who are ahead of the attack line, with lip lacerations and dental fractures being the most common events.


Author(s):  
Celina Elias D’souza ◽  
Mandar Malawade

Background: There is a large incidence of congenital thoracic abnormalities that manifest as deformities and or defects of anterior chest walls. Thoracic abnormalities in preterm infants may also be associated with malpositioning in the incubator in the presence of respiratory disease and prolonged mechanical ventilation. Immaturity of respiratory and musculoskeletal system need to compromise biomechanical function of thorax. Thus, the purpose of the study is to access the thoracic alteration and the factors associated with its abnormalities in the infants born prematurely. Objective: Assess thoracic alteration in premature infants.  Methods: This was an observational study with infants in first year of age, born prematurely with birth weight < 2000g. Exclusion criteria were: major congenital malformations as defined by the centers for disease contol and prevention, grade III/IV intraventricular hemorrhage or preventricular leucomalacia. Physical examinations were performed independently to assess shoulder elevation and thoracic alterations. Results: 34 infants born prematurely were included for the study according to the inclusion criteria from which 20 infants (58.8%) showed thoracic abnormalities and remaining 14 infants (41.1%) were without abnormalities. Conclusion: The prevalence of thoracic abnormalities was high in infants born prematurely, and was associated with pulmonary disease, and may also have compromised the growth rate of these infants during the first year of life.


2019 ◽  
Vol 8 (2) ◽  
pp. 158
Author(s):  
Abrar Arbhiwa Tanguirsyaf Siregar ◽  
Shalita Dastamuar ◽  
Theodorus Theodorus ◽  
Marta Hendry

<span lang="EN-US">Hypospadias is an anomaly of meatus urethra externus on ventral penis. It caused by incomplete fusion of urethral folds. The purpose of this study was to investigate the prevalence of hypospadias with undescended testis in the </span><span>Department of Surgery</span><span lang="EN-US"> Mohammad Hoesin Hospital in Palembang Indonesia. A prevalence study was done in the Medical Records Department of Mohammad Hoesin Hospital from July 2018 to February of 2019. 103 patients met study inclusion criteria. Univariate analysis of the patients’ data was conducted using IBM SPSS Statistics 25. The study found that hypospadias was most common in the age group of 1 to 5 years old (49.5%) and the most common type of hypospadias was severe hypospadias (68.9%). Furthermore, 7 out of 103 patients (6.8%) were hypospadias patients with undescended testis and the most common types of undescended testis among them were bilateral undescended testis and left undescended testis with 3 patients each (42,85%). </span><span>Prevalence of hypospadias with undescended testis were 7 people (6,8%).</span>


2021 ◽  
Vol 2 (1) ◽  
pp. 67-74
Author(s):  
Dara Prameswari ◽  
M. Totong Kamaluddin ◽  
Nita Parisa

Rationality of Diclofenac Use in Osteoarthritis Outpatient Case at RSUP MH Palembang in January-March 2018. Osteoarthritis (OA) is the most common disease in joints that affects people in their middle until late years. In Indonesia the prevalence of OA is relatively high and disturbs their daily activity. Diclofenac is one of the drug of choice in treating OA. To avoid multiple side effects from Diclofenac use, the usage must be in accordance to rationality indicators which are correct dose, correct frequency, and correct length of use. This study is aimed to know the rationality of Diclofenac use in Osteoarthritis outpatient cases at RSUP Mohammad Hoesin Palembang. This study is a descriptive observational with a cross-sectional approach to know the rationality of Diclofenac use in outpatient cases of osteoarthritis at RSUP Mohammad Hoesin Palembang. Samples were medical records of OA patients in outpatient setting from January to March 2018 which fulfilled the inclusion and exclusion criteria. Sampling technique used was total sampling. The amount of samples fulfilling the inclusion criteria were 201 patients, with the most were aged 46-65 years (60.2%), female (55.7%), and has a history of comorbidity which includes low back pain (22.8%). The result of this study shows pattern of Diclofenac use with dosage of 2 x 25mg (73.6%), length of use about <7 days (57.2%). In combination with other drugs there were no interaction to be found (84.4%), or synergistic interaction (8.5%) and antagonistic interaction (7.1%). The use of diclofenac in osteoarthritis cases at outpatient setting in RSUP Dr Mohammad Hoesin Palembang is rational and needs to be maintained.


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