Bioactive Glasses in Dental Applications (Literature Review)

Ola Saleh Mahdi

doi:10.29196/jubes.v27i2.2339

Bioactive Glasses in Dental Applications (Literature Review)

Journal of University of Babylon for Engineering Sciences ◽

10.29196/jubes.v27i2.2339 ◽

2019 ◽

Vol 27 (2) ◽

pp. 207-213 ◽

Cited By ~ 1

Author(s):

Ola Saleh Mahdi

Keyword(s):

Literature Review ◽

Sol Gel ◽

Antibacterial Properties ◽

Biocompatible Materials ◽

The Body ◽

Wide Scope ◽

Bioactive Glasses ◽

Course Of Action ◽

Dental Applications

Bioactive glasses are silicate-grounded and can course of action a strong substance connect through the tissues. These biomaterials are exceptionally biocompatible and can shape a hydroxyapatite layer when embedded in the body or absorbed the recreated body liquid. Because of a few detriments, regular glass preparing technique, including softening of glass parts is supplanted by sol-gel strategy with a substantial number of advantages, for example, low handling temperature, higher immaculateness and homogeneity and along these lines better control of bioactivity. Bioactive glasses have a wide scope of utilizations, especially in dentistry. These glasses can be utilized as particulates or solid shapes and permeable or thick develops in various applications, for example, remineralization or extreme touchiness treatment. A few properties of bioactive glasses, for example, antibacterial properties can be advanced by including diverse components into the glass. Bioactive glasses can likewise be utilized to adjust diverse biocompatible materials that should be bioactive. This investigation surveys the critical advancements of bioactive glasses in dentistry. Besides, we will examine the field of bioactive glasses from starting to the present advancements, which incorporates preparing techniques, applications, and properties of these glasses.

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Ion Release Behavior and Apatite-Forming Ability of Sol-Gel Derived 70S30C Bioactive Glass with Magnesium/Zinc Substitution

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.493-494.55 ◽

2011 ◽

Vol 493-494 ◽

pp. 55-60 ◽

Cited By ~ 6

Author(s):

A.Ansari Hamedani ◽

F. Moztarzadeh ◽

D. Bizari ◽

M. Ashuri ◽

M. Tahriri

Keyword(s):

Tissue Engineering ◽

Degradation Products ◽

Calcium Phosphates ◽

Sol Gel ◽

The Body ◽

Apatite Formation ◽

Ion Release ◽

Ph Change ◽

Bioactive Glasses ◽

Glass Powders

Bioactive glasses not only can bond to hard tissues of the body, are also able to release ions that have stimulatory effects on cells and so are regarded as promising candidate materials for gene activating purposes in tissue engineering applications. In this research the effect of co-substitution of Magnesium and Zinc for Calcium on bioactivity of binary sol-gel derived glass 70S30C (70 mol. % SiO2, 30 mol. % CaO) was investigated. Calcium phosphates forming ability tests and investigation of glass degradation products in simulated body fluid (SBF) were performed as follows.After sol-gel synthesis of glass powders of comparable and under 38 μm particle size distributions, their state of being amorphous was investigated using X-ray diffraction. Then for in vitro investigation of bioactivity, ion release, pH change and Calcium phosphate formation during immersion of glass powders in SBF at 37 ͦC up to 2 weeks were studied. Infrared spectroscopy was performed on the reacted glass powders.Results indicate that substitution of Zinc for Calcium suppresses crystalline apatite formation more effectively than substitution of Magnesium for Calcium and help us design modified compositions of magnesium and zinc containing bioactive glasses that can find applications in bone and also cartillage tissue engineering.

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A facile synthesis of mono dispersed spherical silver doped bioactive glass nanoparticle

Journal of Materials Science Materials in Medicine ◽

10.1007/s10856-021-06496-9 ◽

2021 ◽

Vol 32 (3) ◽

Author(s):

Zahra Kazemian ◽

Mohammad Varzandeh ◽

Sheyda Labbaf

Keyword(s):

Body Fluid ◽

Inhibitory Concentration ◽

Minimum Bactericidal Concentration ◽

Sol Gel ◽

Medical Applications ◽

X Ray Diffraction ◽

Facile Synthesis ◽

Bioactive Glasses ◽

X Ray ◽

Dental Applications

AbstractBioactive glasses have attracted enormous attention in the field of biomaterials for dental and medical applications. Incorporation of antibacterial ions within BGs has been proved to be a promising approach to fortify their bactericidal character. In this study, homogenous BGs containing silver (Ag) ions were synthesized by sol–gel method. Subsequently, the presence of the embedded ions were characterized by X-ray fluorescence (XRF) elemental analysis and energy dispersive X-ray (EDX) spectroscopy. Moreover, released ions were measured in simulated body fluid (SBF) and their antibacterial effectiveness was further verified using minimum bactericidal concentration (MBC) and minimum inhibitory concentration (MIC) tests. A crystalline hydroxyapatite layer was formed on the Ag-BG surfaces at day 5 approved by X-ray diffraction indicating the preserved bioactivity. The resultant uniform, mono-dispersed and dense nanoparticles show 19 great potential for a range of orthopedic and dental applications.

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Nature and Therapeutic Potential of Silica-based Mesoporous Bioactive Glass

Scientific Inquiry and Review ◽

10.32350/sir.32.03 ◽

2019 ◽

Vol 3 (2) ◽

pp. 17-26

Author(s):

Muhammad Ikram ◽

Shabbir Hussain ◽

Mohsin Javed

Keyword(s):

Biomedical Applications ◽

Therapeutic Potential ◽

Sol Gel ◽

Antibacterial Properties ◽

Bioactive Glasses ◽

Bioactive Materials ◽

Copper Zinc ◽

Gel Technique ◽

Tissue Recovery ◽

First Time

Bioactive materials have received much consideration in the last couple of years because of their astounding properties in various fields. Bioactive Glasses (BGs) are utilized as part of biomedical applications, such as antibacterial materials. BGs can be delivered by means of dissolve extinguishing strategy or sol-gel technique. Bactericidal silver-doped sol-gel inferred mesoporous silica-based bioactive glasses were accounted for the first time in 2000, having the synthesis 76SiO2-19CaO-2P2O5-3Ag2O (wt%) and a mean pore width of 28 nm. Bioactive glasses doped with metallic elements such as silver, copper, zinc, cerium and gallium are the focus of this audit in which SiO2, SiO2-CaO and SiO2-CaO-P2O5 frameworks are incorporated as the parent glass creations. Run of the mill uses of mesoporous BGs doped with antibacterial particles incorporate bone tissue recovery, multifunctional earthenware coatings for orthopedic gadgets and orbital inserts, scaffolds with upgraded angiogenesis potential, osteostimulation and antibacterial properties for the treatment of various bone imperfections and also in wound recuperating.

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High Heels sebagai Agensi bagi Tubuh Wanita

Anthropos Jurnal Antropologi Sosial dan Budaya (Journal of Social and Cultural Anthropology) ◽

10.24114/antro.v5i2.15362 ◽

2020 ◽

Vol 5 (2) ◽

pp. 196

Author(s):

Sunandar Macpal ◽

Fathianabilla Azhar

Keyword(s):

Body Image ◽

Literature Review ◽

The Body ◽

The Other ◽

Body Image Disturbance ◽

Other Hand ◽

High Heels ◽

Experience Pain ◽

Woman's Body

The aims of this paper is to explain the use of high heels as an agency for a woman's body. Agency context refers to pain in the body but pain is perceived as something positive. In this paper, the method used is a literature review by reviewing writings related to the use of high heels. The findings in this paper that women experience body image disturbance or anxiety because they feel themselves are not beautiful or not attractive. The use of high heels, makes women more attractive and more confident, on the other hand the use of high heels actually makes women feel pain and discomfort. However, for the achievement of beauty standards, women voluntarily allow their bodies to experience pain. However, the agency's willingness to beauty standards here is meaningless without filtering and directly accepted. Instead women keep negotiating with themselves so as to make a decision why use high heels.

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Development of Novel Oral Formulations of Disulfide Antioxidants Based on Porous Silica for Controlled Release of the Drugs

Materials ◽

10.3390/ma14040963 ◽

2021 ◽

Vol 14 (4) ◽

pp. 963

Author(s):

Ekaterina S. Dolinina ◽

Elena V. Parfenyuk

Keyword(s):

Antioxidant Activity ◽

Surface Chemistry ◽

Sol Gel ◽

Porous Silica ◽

The Body ◽

Oral Drug ◽

Therapeutic Concentration ◽

Release Process ◽

Zero Order Kinetics ◽

Long Time

Powerful antioxidant α-lipoic acid (LA) exhibits limited therapeutic efficiency due to its pharmacokinetic properties. Therefore, the purpose of this work was to evaluate the ability of silica-based composites of LA as well as its amide (lipoamide, LM), as new oral drug formulations, to control their release and maintain their therapeutic concentration and antioxidant activity in the body over a long time. The composites synthesized at different sol–gel synthesis pH and based on silica matrixes with various surface chemistry were investigated. The release behavior of the composites in media mimicking pH of digestive fluids (pH 1.6, 6.8, and 7.4) was revealed. The effects of chemical structure of the antioxidants, synthesis pH, surface chemistry of the silica matrixes in the composites as well as the pH of release medium on kinetic parameters of the drug release and mechanisms of the process were discussed. The comparative analysis of the obtained data allowed the determination of the most promising composites. Using these composites, modeling of the release process of the antioxidants in accordance with transit conditions of the drugs in stomach, proximal, and distal parts of small intestine and colon was carried out. The composites exhibited the release close to the zero order kinetics and maintained the therapeutic concentration of the drugs and antioxidant effect in all parts of the intestine for up to 24 h. The obtained results showed that encapsulation of LA and LM in the silica matrixes is a promising way to improve their bioavailability and antioxidant activity.

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How to express the antioxidant properties of substances properly?

Chemical Papers ◽

10.1007/s11696-021-01799-1 ◽

2021 ◽

Author(s):

Małgorzata Olszowy-Tomczyk

Keyword(s):

Oxidative Stress ◽

Reactive Oxygen Species ◽

Literature Review ◽

Antioxidant Activities ◽

Antioxidant Properties ◽

Reactive Oxygen ◽

The Body ◽

Universal Method ◽

Oxygen Species ◽

Good Tool

AbstractOxidative stress, associated with an imbalance between the oxidants (reactive oxygen species) and the antioxidants in the body, contributes to the development of many diseases. The body’s fight against reactive oxygen species is supported by antioxidants. Nowadays, there are too many analytical methods, but there is no one universal technique for assessing antioxidant properties. Moreover, the applied different ways of expressing the results lead to their incompatibility and unreasonable interpretation. The paper is a literature review concerning the most frequent ways of antioxidant activities expression and for an easy and universal method of the obtained results discussion. This paper is an attempt to point out their disadvantages and advantages. The manuscript can support the searching interpretation of the obtained results which will be a good tool for the development of a number of fields, especially medicine what can help in the future detection and treatment of many serious diseases. Graphic abstract

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Preparation of bioactive and antibacterial PMMA-based bone cement by modification with quaternary ammonium and alkoxysilane

Journal of Biomaterials Applications ◽

10.1177/08853282211004413 ◽

2021 ◽

pp. 088532822110044

Author(s):

Haiyang Wang ◽

Toshinari Maeda ◽

Toshiki Miyazaki

Keyword(s):

Antibacterial Activity ◽

Methyl Methacrylate ◽

Bone Cement ◽

Setting Time ◽

Antibacterial Properties ◽

The Body ◽

Apatite Formation ◽

Gram Positive ◽

E Coli ◽

Gram Positive Bacteria

Bone cement based on poly(methyl methacrylate) (PMMA) powder and methyl methacrylate (MMA) liquid is a very popular biomaterial used for the fixation of artificial joints. However, there is a risk of this cement loosening from bone because of a lack of bone-bonding bioactivity. Apatite formation in the body environment is a prerequisite for cement bioactivity. Additionally, suppression of infection during implantation is required for bone cements to be successfully introduced into the human body. In this study, we modified PMMA cement with γ-methacryloxypropyltrimetoxysilane and calcium acetate to introduce bioactive properties and 2-( tert-butylamino)ethyl methacrylate (TBAEMA) to provide antibacterial properties. The long-term antibacterial activity is attributed to the copolymerization of TBAEMA and MMA. As the TBAEMA content increased, the setting time increased and the compressive strength decreased. After soaking in simulated body fluid, an apatite layer was detected within 7 days, irrespective of the TBAEMA content. The cement showed better antibacterial activity against Gram-negative E. Coli than Gram-positive bacteria; however, of the Gram-positive bacteria investigated, B. subtilis was more susceptible than S. aureus.

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Synthesis, Structural, Morphological and Thermal Characterization of Five Different Silica-Polyethylene Glycol-Chlorogenic Acid Hybrid Materials

Polymers ◽

10.3390/polym13101586 ◽

2021 ◽

Vol 13 (10) ◽

pp. 1586

Author(s):

Michelina Catauro ◽

Pavel Šiler ◽

Jiří Másilko ◽

Roberta Risoluti ◽

Stefano Vecchio Ciprioti

Keyword(s):

Polyethylene Glycol ◽

Chlorogenic Acid ◽

Hybrid Materials ◽

Sol Gel ◽

Antibacterial Properties ◽

Silica Matrix ◽

Sem Images ◽

Fixed Amount ◽

Organic Components ◽

Free Material

The present study investigated the structure, morphology, thermal behavior, and bacterial growth analysis of novel three-component hybrid materials synthesized by the sol-gel method. The inorganic silica matrix was weakly bonded to the network of two organic components: a well-known polymer such as polyethylene glycol (PEG, average molar mass of about 4000 g/mol), and an antioxidant constituted by chlorogenic acid (CGA). In particular, a first series was made by a 50 wt% PEG-based (CGA-free) silica hybrid along with two 50 wt% PEG-based hybrids containing 10 and 20 wt% of CGA (denoted as SP50, SP50C10 and SP50C20, respectively). A second series contained a fixed amount of CGA (20 wt%) in silica-based hybrids: one was the PEG-free material (SC20) and the other two contained 12 and 50 wt% of PEG, respectively (SP12C20 and SP50C20, respectively), being the latter already included in the first series. The X-ray diffraction (XRD) patterns and scanning electron microscope (SEM) images of freshly prepared materials confirmed that all the materials were amorphous and homogeneous regardless of the content of PEG or CGA. The thermogravimetric (TG) analysis revealed a higher water content was adsorbed into the two component hybrids (SP50 and SC20) because of the availability of a larger number of H-bonds to be formed with water with respect to those of silica/PEG/CGA (SPC), where silica matrix was involved in these bonds with both organic components. Conversely, the PEG-rich materials (SP50C10 and SP50C20, both with 50 wt% of the polymer) retained a lower content of water. Decomposition of PEG and CGA occurred in almost the same temperature interval regardless of the content of each organic component. The antibacterial properties of the SiO2/PEG/CGA hybrid materials were studied in pellets using either Escherichia coli and Enterococcus faecalis, respectively. Excellent antibacterial activity was found against both bacteria regardless of the amount of polymer in the hybrids.

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Three-Dimensional Printing of Hydroxyapatite Composites for Biomedical Application

Crystals ◽

10.3390/cryst11040353 ◽

2021 ◽

Vol 11 (4) ◽

pp. 353

Author(s):

Yanting Han ◽

Qianqian Wei ◽

Pengbo Chang ◽

Kehui Hu ◽

Oseweuba Valentine Okoro ◽

...

Keyword(s):

Tissue Engineering ◽

3D Printing ◽

Biomedical Application ◽

Three Dimensional ◽

Antibacterial Properties ◽

Natural Polymers ◽

Three Dimensional Printing ◽

3D Printed ◽

Dental Applications ◽

Hard Tissue Engineering

Hydroxyapatite (HA) and HA-based nanocomposites have been recognized as ideal biomaterials in hard tissue engineering because of their compositional similarity to bioapatite. However, the traditional HA-based nanocomposites fabrication techniques still limit the utilization of HA in bone, cartilage, dental, applications, and other fields. In recent years, three-dimensional (3D) printing has been shown to provide a fast, precise, controllable, and scalable fabrication approach for the synthesis of HA-based scaffolds. This review therefore explores available 3D printing technologies for the preparation of porous HA-based nanocomposites. In the present review, different 3D printed HA-based scaffolds composited with natural polymers and/or synthetic polymers are discussed. Furthermore, the desired properties of HA-based composites via 3D printing such as porosity, mechanical properties, biodegradability, and antibacterial properties are extensively explored. Lastly, the applications and the next generation of HA-based nanocomposites for tissue engineering are discussed.

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