scholarly journals MANAGEMENT OF INFANTS LESS THAN SIX MONTHS WITH SEVERE ACUTE MALNUTRITION (SAM).

2020 ◽  
Vol 27 (06) ◽  
pp. 1113-1118
Author(s):  
Saadia Khan ◽  
Gul Hasan ◽  
Ibad Ali ◽  
Reema Arshad ◽  
Imrana Ali ◽  
...  

Objectives: To determine the average weight gain after lactation counseling therapy in infants up to six months of age having severe acute malnutrition. Study Design: Quasi experimental trial. Setting: Stabilization Center Unit, the Children’s Hospital & the Institute of Child Health, Multan. Period: 1st October 2015 to 1st October 2016. Material & Methods: A total of 205 children with SAM were included in this study using non-probability consecutive sampling technique. Mothers of these children were motivated for more than 8 feeds/day, positioning and attachment at breast feeding was advised, demonstrated and monitored. All the data obtained was entered and analyzed by SPSS version 20. Results: Of these 205 study cases, 142 (69.3%) were boys and 63 (30.75) were girls. Mean age of our study cases was 3.75 ± 1.39 months (with minimum age of our study cases was 2 months while maximum age was 6 months). Of these 205 study cases, 101 (49.3 %) were from rural areas while 104 (50.7%) were from urban areas. Mothers of 117 (57.1%) study cases were literate while 88 (42.9%) were illiterate. Majority of our study cases i.e. 129 (62.9%) were from middle income background and 76 (37.1%) were from poor social background. Partial breast feeding was positive in 145 (70.7%) of our study cases and no breast feeding was noted in 60 (29.3%). Mean baseline weight was 2737.07± 585.60 grams. Mean weight at discharge was 2995.37 ± 621.97 grams and mean weight gain was 800.0 ± 258. 29 grams. Average daily weight gain was noted to be 11.27 ± 4.73 g/kg/day. Conclusion: Our study results have shown that lactation counseling therapy significantly improves weight gain in children under 6 months of age with severe acute malnutrition. Mothers of infants presenting with malnutrition must be counselled to breast feed to improve their clinical outcomes. Mean weight gain was significantly associated with maternal education and socioeconomic status. Further studies are suggested from different parts of the country to generate our local data at national level which may be incorporated for national health policy guidelines.

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Erin Boyd

Abstract Objectives Identify the most significant factors affecting the trajectory of recovery from severe acute malnutrition (SAM), as measured by average daily weight gain in each child 6–59 months of age who were diagnosed and treated for SAM and treated, adjusting for covariates including: breastfeeding status, number of children in household, illness, and distance to health center. Hypothesis 1a: Children 6–59 months enrolled in SAM treatment have slower times to recovery and slower weight gain if they are admitted for treatment at a lower anthropometric cut-off admission (weight for height z-score < −4) than children admitted for treatment at a higher anthropometric cut-off (weight for height z-score ≥ −4). Hypothesis 1b: Older children (24–59 months) recover more quickly than younger children (6–23 months) controlling for ration size. Methods A retrospective panel data analysis on children 6–59 months enrolled in standard outpatient treatment for severe acute malnutrition (SAM) between 2014 and 2016 was conducted. The study period was between September-December 2018. Children were exhaustively sampled. Children with edema, children with implausible z-scores for W/H (<−5 and >5) and H/A (<−6 and >6), children who were referred for inpatient therapeutic feeding to a stabilization center, and children from the same household, except in the case of twins, were eliminated from the analysis. There was one database per country. A total of 1384 children between 6–59 months were included in the analysis. Results The most significant factors affecting the proportional weight gain include age at enrollment (P = 0.001, 95%CI = −0.00—0.00) and Weight for height z-score (WHZ) (P = 0.00, 95%CI = 0.04—0.05) in each child 6–59 months of age who were diagnosed with SAM and treated, adjusting for covariates including: breastfeeding status, number of children in household, illness, and distance to health center. Sex of child did not significantly affect proportional weight gain (P = 0.404, 95%CI = −0.012–0.005). Conclusions The existing protocol to treat severe acute malnutrition should be modified to treat younger children and children who are admitted with a lower weight for height z-score due to different vulnerabilities. Funding Sources The research was conducted as part of a dissertation at The Friedman School of Nutrition Science and Policy at Tufts University. Data were obtained from World Vision.


2020 ◽  
Vol 42 ◽  
pp. e2020003 ◽  
Author(s):  
Mekonen Adimasu ◽  
Girum Sebsibie ◽  
Fikrtemariam Abebe ◽  
Getaneh Baye ◽  
Kerebih Abere

OBJECTIVES: Recovery time from severe acute malnutrition (SAM) is often a neglected topic despite its clinical impact. Although a few studies have examined nutritional recovery time, the length of hospitalization in those studies varied greatly. Therefore, the aim of this study was to determine the recovery time from SAM and to identify predictors of length of hospitalization among under-5 children.METHODS: A retrospective cohort study was conducted among 423 under-5 children with SAM who had been admitted to Yekatit 12 Hospital. Kaplan-Meier analysis was used to estimate time to nutritional recovery, and Cox proportional hazard regression analysis was performed to determine independent predictors.RESULTS: The nutritional recovery rate was 81.3%, and the median recovery time was 15.00 days (95% confidence interval [CI], 13.61 to 16.39). Age, daily weight gain per kilogram of body weight, vaccination status, and the existence of at least 1 comorbidity (e.g., pneumonia, stunting, shock, and deworming) were found to be significant independent predictors of nutritional recovery time. The adjusted hazard ratio (aHR) for nutritional recovery decreased by 1.9% for every 1-month increase in child age (aHR, 0.98; 95% CI, 0.97 to 0.99).CONCLUSIONS: The overall nutritional recovery time in this study was within the Sphere standards. However, approximately 13.0% of children stayed in the hospital for more than 28.00 days, which is an unacceptably large proportion. Daily weight gain of ≥8 g/kg, full vaccination, and deworming with albendazole or mebendazole reduced nutritional recovery time. Conversely, older age, pneumonia, stunting, and shock increased nutritional recovery time.


Author(s):  
Kieran O’Brien ◽  
Ali Sié ◽  
Clarisse Dah ◽  
Millogo Ourohiré ◽  
Moussa Ouedraogo ◽  
...  

Azithromycin is a promising alternative to amoxicillin in the management of uncomplicated severe acute malnutrition (SAM) as it can be administered as a single dose and has efficacy against several pathogens causing infectious disease and mortality in children under 5. In this pilot trial, we aimed to establish the feasibility of a larger randomized controlled trial and provide preliminary evidence comparing the effect of azithromycin to amoxicillin on weight gain in children with uncomplicated SAM. We enrolled children 6–59 months old with uncomplicated SAM at six healthcare centers in Burkina Faso. Participants were randomized to a single dose of azithromycin or a 7-day course of amoxicillin and followed weekly until nutritional recovery and again at 8 weeks. Apart from antibiotics, participants received standard of care, which includes ready-to-use therapeutic food. Primary feasibility outcomes included enrollment potential, refusals, and loss to follow-up. The primary clinical outcome was weight gain (g/kg/day) over 8 weeks. Outcome assessors were masked. Between June and October 2020, 312 children were screened, 301 were enrolled with zero refusals, and 282 (93.6%) completed the 8-week visit. Average weight gain was 2.5 g/kg/day (standard deviation [SD] 2.0) in the azithromycin group and 2.6 (SD 1.7) in the amoxicillin group (mean difference −0.1, 95% CI −0.5 to 0.3, P = 0.63). Fewer adverse events were reported in the azithromycin group (risk ratio 0.50, 95% CI 0.31–0.82, P = 0.006). With strong enrollment and follow-up, a fully powered trial in this setting is feasible.


2020 ◽  
Vol 3 (2) ◽  
Author(s):  
Rico Rico ◽  
Novi Eka Wati ◽  
Adisti Rastosari

The objective of the researh was to study the effect of additions soybean meal in ration on the feed consumption, daily weight gain and feed convertion in Simmental cattle. The experiment used eight male Simmental cattle around 2 years old with an average weight of 198,65 ± 14,57 kilograms. The cattle kept for 35 days and given rations P0 (rations ranchers) and P1 (rations plus soybean meal). Data was obtained, then analyzed using independent sample t-test assisted with SPSS version 17.00 software. The result showed that the addition of soybean meal did not affect on dry matter consumption, daily weight gain, and feed convertion but, the crude protein consumption was increased. Keywords: dry matter consumption, daily weight gain, feed convertion


2009 ◽  
Vol 33 (6) ◽  
pp. 1643-1648
Author(s):  
Lucas Alberto Teixeira de Rezende ◽  
Júlio César Teixeira ◽  
Antônio Ricardo Evangelista ◽  
Juan Ramón Olalquiaga Pérez ◽  
Joel Augusto Muniz ◽  
...  

This work was carried out to evaluate the effect of supplements based on non-protein nitrogen (NPN) as: urea, amirea and multinutritional block, on live weight gain and cost analysis for cattle kept in pastures. During a period of 104 days(April to July 2004), 40 crossbreed bulls, uncastrated and initial average weight of 379kg, were allocated into 4 paddocks with Brachiaria brizantha cv. Marandu, in continuous pasture system receiving, in troughs, the following treatments: mineral salt (control), protein supplement containing amirea, protein supplement containing urea and multinutritional block. The experimental design used was randomized blocks with repetition within the block. Results of availability bromatological composition of pasture, supplement consumption and daily weight gain of animals were evaluated in two experimental sub-periods: 0 to 45 and 45 to 90 days. In the first sub-period, there was no effect of treatments (P>0.05) on daily weight gain but in the second sub-period, the multinutritional block showed smaller (P<0.05) weight gain than the ones which were similar among themselves, being: 0.60; 0.59; 0.61 and 0.22kg/animal/day, respectively, for the treatments with mineral salt, amirea, urea and multinutritional block. Before these edafoclimatic conditions, the period and duration of the experiment, the supplementation with mineral salt provided the higher profit.


Author(s):  
Rajesh Kumar Sinha ◽  
Asha Kiran ◽  
Vivek Kashyap ◽  
Praveen Kumar

Background: Children with severe acute malnutrition (SAM) having medical complications require immediate care at malnutrition treatment centers (MTC). Thus, it becomes important to assess the effect and treatment cost of such children in these facilities. Hence, the present study was done with these aims in two MTCs in Jharkhand, India.Methods: A retrospective record review was done of the children admitted to these two MTCs between 1st April 2017 and 31st March 2018. A predesigned proforma was used to collect child related information. The data collected was entered in Microsoft excel sheet and analysed.Results: Majority of the admitted children (90.6%) were in 6-23 months age group. 358 (51.5%) children were females. Only, 194 (27.9%) children admitted were SAM had any medical complication. 690 (99.3%) children were discharged of whom 499 (72.3%) were discharged after achieving the target weight. The average weight gain during their stay was 8.1±2.4 g/kg/day and average length of stay was 16.7±3.2 days. Post discharge follow up rates were found to be low and only 130 (18.8%) children completed all three follow ups. Average cost per SAM child treated was Rs. 18,599 (US$ 272) and per SAM child cured was Rs. 25,904 (US$ 379).Conclusions: MTCs are effective in managing medically complicated SAM children. However, improvements are necessary to ensure that more such children should be treated at facility level, complimented with a community based programme for managing uncomplicated SAM children to improve coverage and ensure continuum of care.


2021 ◽  
Vol 48 (1) ◽  
pp. 152-165
Author(s):  
A. T. Amos ◽  
A. O. Oso ◽  
O. J. Durojaiye ◽  
K. Agazue ◽  
A. O. Obanla ◽  
...  

In a 56-day feeding trial, an experiment was conducted to determine the effects of replacing maize with different levels of ensiled cassava root-leaf blends (ECRLB) on growth, carcass yield, blood profile and economics of production of weaner rabbits. Five experimental diets were formulated and fed to the animals; diet 1= a maize based diet (control diet), diet 2= 30% maize + 10% ECRLB, diet 3 = 20% maize + 20% ECRLB, diet 4= 10 % maize + 30% ECRLB, diet 5= 40% ECRLB. A total number of forty weaner rabbits with an initial average weight of 574.09g±20.03g were randomly allocated to the five dietary treatments in a completely randomized design (CRD) with eight animals per treatment. Data were collected on growth indices, economics of production, carcass characteristics and blood profile Increased (P<0.05) weight gain was observed as the percentage inclusion of ECRLB increased. Rabbits on diet 4 (10 % maize + 30% ECRLB) and 5 (40% ECRLB) recorded the highest (P<0.05) daily weight gain with a corresponding highest (P<0.5) final body weight. Similar FCR were recorded across the treatments Economics of production of animals on diets containing 30 and 40% ECRLB was the best (P<0.05). Carcass indices were not significantly (P>0.0) affected by the experimental diets. Rabbits fed ECRLB recorded lower (P<0.05) serum cholesterol and higher (P<0.05) serum glucose concentration compared to control. In conclusion dietary inclusion of ECRLB up to 40% improved performance and did not show any deleterious effects on all indices examined and is recommended.     Au cours d'un essai d'alimentation de 56 jours, une expérience a été menée pour déterminer les effets du remplacement du maïs par différents niveaux de mélanges racines-feuilles de manioc ensilées (le 'ECRLB) sur la croissance, le rendement de carcasses, le profil sanguin et l'économie de la production de lapins sevrés. Cinq régimes expérimentaux ont été formulés et nourris aux animaux ; régime 1= régime à base de maïs (régime de contrôle), régime 2= 30% maïs + 10% ECRLB, régime 3 = 20% maïs + 20% ECRLB, régime 4= 10% maïs + 30% ECRLB, régime 5= 40% ECRLB. Un nombre total de quarante lapins sevrés d'un poids moyen initial de 574,09 g±20,03 g ont été attribués au hasard aux cinq traitements diététiques dans une conception complètement randomisée (CRD) avec huit animaux par traitement. Des données ont été recueillies sur les indices de croissance, l'économie de la production, les caractéristiques de la carcasse et le profil sanguin. Le gain de poids accru (P<0,05) a été observé à mesure que l'inclusion en pourcentage de l'ECRLB augmentait. Les lapins de l'alimentation 4 (10 % de maïs + 30 % d'ECRLB) et 5 (40 % d'ECRLB) ont enregistré le gain de poids quotidien le plus élevé (P<0,05) avec un poids corporel final correspondant le plus élevé (P<0,5). Les 'FCR' similaires ont été enregistrés à travers les traitements Économie de la production d'animaux sur les régimes contenant 30 et 40% ECRLB a été le meilleur (P<0,05). Les Indices carcasse n'étaient pas significativement (P>0,0) affectés par les régimes expérimentaux. Les lapins nourris à l'ECRLB ont enregistré un taux de cholestérol sérique inférieur (P<0,05) et une concentration plus élevée de glucose sérique (P<0,05) par rapport au contrôle. En conclusion, l'inclusion alimentaire de l'ECRLB jusqu'à 40 % a amélioré les performances et n'a pas montré d'effets délétères sur tous les indices examinés et est recommandée.


2020 ◽  
Vol 20 (06) ◽  
pp. 16622-16637
Author(s):  
Nago E ◽  
◽  
JO Agossadou ◽  
FJ Chadare ◽  
S Houndji ◽  
...  

Inappropriate feeding, too early introduction of complementary foods and restriction in food selection are a major cause of malnutrition among young children in developing countries. Food-to-food fortification is a good strategy to enhance the nutritional quality of children’s diet. This strategy is more and more promoted because it allows delivery of micronutrients to a large population in a cost-effective manner.The present study aimed at testing the effect of the consumption of sorghum porridge fortified with moringa leaf powder and baobab fruit pulp on the nutritional status of children aged 6 to 59 months in Northern Benin. A two-week intervention was implemented in Tanguiéta (Benin) among children affected by moderate acute malnutrition, using 400g of fermented sorghum porridge fortified with15g of a designed mix of moringa leaf powder and baobab fruit pulp. Sixty-three children aged 6–59 months who had malnutrition assessed by anthropometry were randomly selected and assigned to a treatment or a control group. Children in the treatment group consumed the fortified formula daily for two weeks in a nutritional rehabilitation hearth whereas those in the control group had their habitual diet. Their nutritional status was evaluated using anthropometry. Recovery rate and average weight gain of children were computed.Results show that daily consumption of the fortified food for two weeks did not significantly (P> 0.05) increase children’s weight in treatment vs. control. However, average weight gain was 9.85g/kg/day in the treatment group and total recovery rate at risk of malnutrition and moderate acute malnutrition was 62.50% among children who fully complied with the intervention. Fermented sorghum porridge fortified with moringa leaf powder and baobab fruit pulp may be promoted to scale in more regions of Benin as a local affordable and effective therapeutic food against child acute malnutrition. Further investigation of its potential effect while accounting for parasitic infection is needed, to eliminate all risks of intestinal micro nutrient malabsorption or malaria and enhance the effectiveness of the fortified food on children’s weight as well as their iron status.


2019 ◽  
Vol 6 (2) ◽  
pp. 602
Author(s):  
Suguna S. ◽  
Vidyasagar V.

Background: The objective of this study is to know the gender variation in number of admissions, severity of malnutrition at the time of admission, gaining of weight and adherence to follow up in children admitted to nutrition rehabilitation center and during follow up.Methods: This is a retrospective study involving the review of existing programme records. Children who were admitted to nutrition rehabilitation centre, district hospital, Chamarajanagar, Karnataka, India, between January 2017 to December 2017 with severe acute malnutrition were involved in the study. The programme included 2 weeks of in-patient care, and four follow-up visits to the NRC subsequently as follows; 1st visit at 7 days, 2nd at 14 days, 3rd at 1 month and 4th at 2 months after discharge.Results: Among 57 children who admitted to NRC females were 30 (52.6%) and males 27 47.4%). 25 among 57 children (43.9%) could sustain weight gain of >5grams/kg/day as per one of the discharge criteria. 13 (52%) were females and 12 (48%) were males. 32(56%) among 57 admitted children to NRC, could achieve <-1SD during entire programmed. 15(46.8%) were females and 17 (53.1%) were males.Conclusions: There was no gender variation in either number of admission or severity of malnutrition at the time of admission or weight gain during NRC programme.


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