NEONATAL HEALTH OUTCOME OF PREGNANT WOMEN WITH DIABETES MELLITUS

Excessive fetal weight attracts attention because it increases perinatal and maternal morbidity and mortality. The prevalence of macrosomia worldwide has increased over the past 2 to 3 decades. This study aimed to determine Neonatal Health Outcome of Pregnant Women with Diabetes Mellitus. The design of this study was analytical with a case control approach. Data used to analyze the incidence of macrosomia based on secondary data from 2014-2018. From the research it can be concluded that diabetes mellitus in pregnancy has a significant relationship with the incidence of macrosomia.

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Gestational diabetes mellitus and macrosomia: An analysis of secondary data

Journal of Health Technology Assessment in Midwifery ◽

10.31101/jhtam.819 ◽

2018 ◽

Vol 1 (2) ◽

pp. 94-98

Author(s):

Mufdlilah Mufdlilah ◽

Fijri Rachmawati

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Maternal Morbidity ◽

Secondary Data ◽

Case Control ◽

Health Issues ◽

Control Approach ◽

The Past ◽

Maternal Morbidity And Mortality

Excessive fetal weight is considered as a health issues because it increases perinatal and maternal morbidity and mortality. The prevalence of macrosomia worldwide has increased over the past 2 to 3 decades. This study aimed to determine correlation between the incidence of gestational diabetes mellitus and macrosomia among pregnant women. The design of this study was analytical with a case control approach. Data used to analyze the incidence of macrosomia based on secondary data from 2014-2018. This research suggested that diabetes mellitus in pregnancy has a significant relationship with the incidence of macrosomia.

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RENAL INJURY AND RECOVERY IN PRE-ECLAMPSIA

Fetal and Maternal Medicine Review ◽

10.1017/s0965539505001622 ◽

2005 ◽

Vol 16 (4) ◽

pp. 323-341

Author(s):

MICHELLE HLADUNEWICH

Keyword(s):

Diabetes Mellitus ◽

Premature Birth ◽

Maternal Age ◽

Maternal Morbidity ◽

Positive Family History ◽

Advanced Maternal Age ◽

Epidemiological Studies ◽

Comorbid Conditions ◽

The Past ◽

Maternal Morbidity And Mortality

Affecting 7–10% of pregnancies, pre-eclampsia is, in fact, the most common glomerular disease worldwide. It remains a leading cause of fetal growth restriction, premature birth, as well as infant and maternal morbidity and mortality. Epidemiological studies have identified numerous risk factors for the development of pre-eclampsia including a positive family history, race, nulliparity, advanced maternal age and the presence of pre-existing co morbidities such as kidney disease, hypertension or diabetes mellitus. The incidence of pre-eclampsia has increased by an alarming 40% over the past decade, likely due to the number of women delaying pregnancy and/or becoming pregnant despite the presence of other comorbid conditions.

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VENOUS THROMBOEMBOLISM DURING PREGNANCY- A REVIEW ARTICLE

10.36106/ijar/4101601 ◽

2021 ◽

pp. 40-43

Author(s):

Madhu Meena ◽

Ramawatar Meena ◽

Khushbu Meena

Keyword(s):

Pulmonary Embolism ◽

Venous Thromboembolism ◽

Pregnant Women ◽

Maternal Morbidity ◽

Recent Literature ◽

Review Article ◽

Vein Thrombosis ◽

The Past ◽

Maternal Morbidity And Mortality ◽

Deep Vein

Deep vein thrombosis and pulmonary embolism are two clinical entities of single diseases causes venous thromboembolism. VTE is an important causes of maternal morbidity and mortality. Diagnosis and treatment of VTE in pregnant women are much more difcult than in non pregnant women. To date numerous studies have evaluated the risk factor and treatment of VTE during pregnancy. In this review we aim to summarise recent literature published within the past few years

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Childhood maltreatment and inflammation among pregnant women with gestational diabetes mellitus: A pilot study

Obstetric Medicine ◽

10.1177/1753495x17701320 ◽

2017 ◽

Vol 10 (3) ◽

pp. 120-124 ◽

Cited By ~ 6

Author(s):

Margaret Bublitz ◽

Suzanne De La Monte ◽

Susan Martin ◽

Lucia Larson ◽

Ghada Bourjeily

Keyword(s):

Diabetes Mellitus ◽

Pilot Study ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Pregnant Women ◽

Birth Outcomes ◽

Childhood Maltreatment ◽

Secondary Data ◽

Past Research ◽

Increased Risk

Background Women with childhood maltreatment histories are at increased risk for adverse birth outcomes. Mechanisms explaining this link are poorly understood. Past research is limited by sampling pregnant women at low risk for adverse maternal and neonatal outcomes. Methods This pilot study was a secondary data analysis of 24 women with gestational diabetes mellitus; 17% of the sample also reported a maltreatment history. Women provided a blood sample to measure inflammatory cytokines and insulin resistance, and saliva samples to measure diurnal cortisol. Birth outcomes for past and current pregnancies were recorded. Results Histories of maltreatment were associated with elevated interleukin-15 and a marginally greater incidence of preterm delivery in current and past pregnancies. Conclusions This pilot study was the first to demonstrate an association between childhood maltreatment history and inflammatory cytokine levels in pregnant women diagnosed with gestational diabetes mellitus.

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How far is too far? A nationwide cross-sectional study for establishing optimal hospital access time for Korean pregnant women

BMJ Open ◽

10.1136/bmjopen-2019-031882 ◽

2019 ◽

Vol 9 (9) ◽

pp. e031882 ◽

Cited By ~ 1

Author(s):

Mi Young Kwak ◽

Seung Mi Lee ◽

Hyun Joo Kim ◽

Sang Jun Eun ◽

Won Mo Jang ◽

...

Keyword(s):

Pregnant Women ◽

Maternal Morbidity ◽

Cross Sectional Study ◽

Obstetric Complications ◽

Access Time ◽

Sectional Study ◽

Cross Sectional ◽

Hospital Access ◽

Maternal Morbidity And Mortality ◽

Delivery Unit

ObjectivesAccess to a delivery unit is a major factor in determining maternal morbidity and mortality. However, there is little information about the optimal access time to a delivery unit. This study aimed to establish the optimal hospital access time (OHAT) for pregnant women in South Korea.DesignNationwide cross-sectional study.SettingWe used the National Health Insurance System database of South Korea.ParticipantsWe analysed the data of 371 341 women who had experienced pregnancy in 2013.Primary and secondary outcome measuresAccess time to hospital was defined as the time required to travel from the patient’s home to the delivery unit. The incidence of obstetric complications was plotted against the access time to hospital. Change-point analysis was performed to identify the OHAT by determining a point wherein the incidence of obstetric complications changed significantly. As a final step, the risk of obstetric complications was compared by type among pregnant women who lived within the OHAT against those who lived outside the OHAT.ResultsThe OHAT associated with each adverse pregnancy outcomes were as follows: inadequate prenatal care, 41–50 min; preeclampsia, 51–60 min; placental abruption, 51–60 min; preterm delivery, 31–40 min; postpartum transfusion, 31–40 min; uterine artery embolisation, 31–40 min; admission to intensive care unit, 31–40 min; and caesarean hysterectomy, 31–40 min. Pregnant women who lived outside the OHAT had significantly higher risk for obstetric complications than those who lived within the OHAT.ConclusionsOur results showed that the OHAT for each obstetric complication ranged between 31 and 60 min. The Korean government should take the OHAT under consideration when establishing interventions for pregnant women who live outside OHAT to reduce maternal morbidity and mortality.

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Heterotopic pregnancy: case report of a successful first trimester metacyesis management and a viable third trimester outcome

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20185448 ◽

2018 ◽

Vol 8 (1) ◽

pp. 332

Author(s):

Arvind Kumar Singh ◽

Shazia Khan

Keyword(s):

Case Report ◽

Maternal Morbidity ◽

Assisted Reproductive Technologies ◽

First Trimester ◽

Reproductive Technologies ◽

Heterotopic Pregnancy ◽

Third Trimester ◽

Intrauterine Pregnancy ◽

The Past ◽

Maternal Morbidity And Mortality

Heterotopic pregnancies are rare combined intra and extrauterine pregnancies, the incidence of which has shown an increase over the past decade with the rising trend in assisted reproductive technologies (0.75-1.5%). Authors report a case of a 29 year old primigravida, a post IVF conception who presented at 6 weeks POG with a ruptured tubal and a viable intrauterine pregnancy. She underwent an emergency laparoscopic right salpingectomy and continued with her intrauterine pregnancy successfully till term. The article emphasizes the need of scanning the adnexa carefully in early pregnancy to diagnose and manage heterotopic pregnancy as early as possible to prevent catastrophic haemorrhage and maternal morbidity and mortality later.

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Dietary Total Antioxidant Capacity and Gestational Diabetes Mellitus: A Case-Control Study

Oxidative Medicine and Cellular Longevity ◽

10.1155/2020/5471316 ◽

2020 ◽

Vol 2020 ◽

pp. 1-9

Author(s):

Elnaz Daneshzad ◽

Hatav Tehrani ◽

Nick Bellissimo ◽

Leila Azadbakht

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Antioxidant Capacity ◽

Pregnant Women ◽

Case Control Study ◽

Case Control ◽

Total Antioxidant ◽

Control Study ◽

Dietary Total Antioxidant Capacity

Background. Elevated oxidative stress status has been reported among pregnant women with gestational diabetes mellitus (GDM). In diabetic condition, glucose and lipid peroxidation, and alteration in antioxidant defense lead to increased free radicals. The objective of this study was to investigate the association between dietary total antioxidant capacity (DTAC) and GDM. Methods. This hospital-based case-control study was conducted in 463 pregnant women (healthy, n=263; GDM, n=200). Anthropometric indices, blood pressure, and biochemical analyses were measured. Dietary intake was assessed by the average of three 24-hour dietary intake records. DTAC was calculated by three indices: ferric reducing ability of plasma (FRAP), total radical-trapping antioxidant parameter (TRAP), and Trolox equivalent antioxidant capacity (TEAC). Multivariable logistic regression was performed to examine the relationship between DTAC and GDM risk in crude and adjusted models. Results. The mean age and BMI were 28.33±6.23 years and 29.67±4.73 kg/m2, respectively. Total energy, protein, and selenium intakes were significantly higher in cases than controls (P<0.05). Moreover, intakes of carbohydrate, vitamins C, B6, and A, manganese, fruits, fruit juices, vegetables, legumes, and FRAP were significantly lower in cases than controls (P<0.05). The risk of gestational diabetes mellitus was 85% lower among those in the highest tertile of FRAP (OR: 0.15; 95% CI: 0.08-0.29). There was no significant association between the risk of GDM and TRAP (OR: 1.62; 95% CI: 0.94-2.79) as well as TEAC (OR: 1.56; 95% CI: 0.89-2.72). Conclusion. Pregnant women who were in the highest tertile of FRAP were at lower risk of GDM. However, larger prospective studies are needed to confirm our findings.

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Hubungan Anemia pada Ibu Hamil dengan Kejadian Persalinan Prematur di RSUD Dr. Moewardi Surakarta

Smart Medical Journal ◽

10.13057/smj.v3i2.37849 ◽

2020 ◽

Vol 3 (2) ◽

pp. 68

Author(s):

Saskia Nandatari ◽

Yudhistya N Insan ◽

Widardo Widardo

Keyword(s):

Pregnant Women ◽

Preterm Labor ◽

Stress Hormones ◽

Case Control ◽

Observational Research ◽

Premature Labor ◽

Research Subjects ◽

Purposive Sampling ◽

Control Approach ◽

Significant Difference

Pendahuluan: Persalinan prematur adalah persalinan yang terjadi pada usia kehamilan sebelum 37 minggu. Persalinan prematur disebabkan oleh berbagai faktor, salah satunya yaitu anemia. Anemia dalam kehamilan merupakan masalah yang cukup sering terjadi terutama di negara berkembang. Anemia dalam kehamilan merupakan keadaan dimana nilai Hemoglobin ibu hamil dibawah 11 g/dl. Keadaan ini mengakibatkan penurunan jumlah oksigen yang dibawa ke janin sehingga mengakibatkan terjadinya hipoksia pada janin. Tujuan penelitian ini adalah untuk mengetahui hubungan antara anemia pada ibu hamil dengan kejadian persalinan prematur di RSUD Dr. Moewardi Surakarta.Metode Penelitian: Penelitian observasional analitik dengan pendekatan case control, dilakukan pada bulan Agustus-September 2019 di RSUD Dr. Moewardi. Subjek penelitian adalah pasien yang mengalami persalinan prematur dan persalinan tidak prematur dalam kurun waktu Juni 2017 sampai dengan Juni 2019 di RSUD Dr. Moewardi. Penelitian dilakukan dengan mengolah data rekam medis. Pada penelitian dipilih sebanyak 70 sampel penelitian, yang terdiri masing-masing 35 sampel untuk kelompok kasus dan kontrol. Sampel diambil menggunakan purposive sampling. Data kemudian dianalisis menggunakan uji Korelasi Koefisien Kontingensi Uji Kappa dan uji T-test Tidak Berpasangan.Hasil: Didapatkan korelasi antara anemia dengan kejadian persalinan prematur bermakna secara statistik. Nilai korelasi sebesar 0,031 menunjukkan korelasi positif dengan kekuatan korelasi yang signifikan dan bermakna secara klinis. Selain itu, didapatkan perbedaan yang bermakna dan signifikan antara rata-rata nilai Hemoglobin ibu hamil dengan persalinan prematur dan tidak prematur, dengan nilai p sebesar 0,003.Simpulan: Terdapat hubungan yang signifikan dan bermakna secara klinis antara anemia pada ibu hamil dengan kejadian persalinan prematur di RSUD Dr. Moewardi Surakarta pada Juni 2017 – Juni 2019. Background: Premature labor is labor that occurs at gestational age before 37 weeks. Premature labor is caused by various factors, one of which is anemia. Anemia in pregnancy, hemoglobin condition of pregnant women under 11 g / dl which is quite common, especially in developing countries. This situation results in a decrease in the amount of oxygen carried to the fetus, resulting in hypoxia in the fetus and stimulates stress hormones associated with labor induction. The purpose of this study was to determine the relationship between anemia in pregnant women with the incidence of preterm labor in Dr. Moewardi Surakarta.Methods: This study was analytic observational research with case-control approach, conducted in August-September 2019 at Dr. Moewardi. Research subjects were patients who experienced preterm labor and non-preterm labor in the period June 2017 to June 2019 at the RSUD Dr. Moewardi. The study was conducted by processing medical record data. In this study 70 research samples were chosen, consisting of 35 samples for the case and control groups. Samples were taken using purposive sampling. Data were then analyzed using the Kappa Test Contingency Coefficient Correlation test and the unpaired T-test.Result: The correlation between anemia and preterm labor was statistically significant. Correlation value (p=0.031) shows a positive correlation with the strength of the correlation that is significant and clinically meaningful. In addition, a significant and significant difference was found between the average hemoglobin value of pregnant women with preterm and non-preterm labor, with a value (p = 0.003).Conclusion: There is a significant and significant relationship between anemia in pregnant women and the incidence of preterm labor in Dr. Moewardi Surakarta in June 2017 - June 2019, where anemia in pregnant women increases the risk of preterm labor.

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Is gross morphology of placenta, umbilical cord, and neonatal outcome in well-controlled gestational diabetes mellitus pregnancy different? A case-control study

International Journal of Reproductive BioMedicine ◽

10.18502/ijrm.v13i6.7282 ◽

2020 ◽

Author(s):

Parichehr Pooransari ◽

Atefeh Ebrahimi ◽

Nataliya Nazemi ◽

Fariba Yaminifar ◽

Zhila Abediasl

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Pregnant Women ◽

Umbilical Cord ◽

Pregnancy Outcomes ◽

Case Control Study ◽

Case Control ◽

Placental Weight ◽

Control Study

Background: The relation of placental gross morphology and the outcome of pregnancies complicated with diabetes mellitus in comparison with healthy pregnancies is not known. Identifying significant differences in pregnancy outcomes in Gestational Diabetes Mellitus (GDM) and healthy pregnancies by the means of morphologic measurements can induce the use of antenatal ultrasonography of placental parameters to predict pregnancy outcomes. Objective: This study aimed to evaluate the relationship between placental morphological parameters of the placenta and cord and the outcomes of pregnancies complicated with diabetes mellitus. Materials and Methods: In this case-control study, which was conducted at two referral perinatology center in Tehran between March 2017 and November 2018, 60 pregnant women with GDM who were controlled with either diet or insulin as the case group and 60 pregnant women without GDM as the control group were enrolled. The study population were selected from patients who had their prenatal care and delivery in Mahdieh and Shohadaye Tajrish Hospital. The data was collected by taking sickness history, using data from patients files, and measuring of placental and newborn parameters after delivery. GDM was diagnosed either by 75 gr or 100 gr oral glucose tolerance tests. Placenta parameters, umbilical cord features, and newborn outcomes were compared between the two groups. Results: Placental weight, diameter, number of lobes, thickness, placental weight tonewborn weight ratio, place of umbilical cord insertion, length, coiling, and diameter of the umbilical cord are similar in two groups. Newborn weight, NICU admission, ABG, and Apgar score are also the same in well-controlled GDM pregnancy and pregnancy without GDM. Conclusion: Good controlled GDM causes no difference in placental gross morphology and pregnancy outcome compared to a healthy pregnancy. Key words: Placenta, Umbilical cord, Gestational diabetes mellitus.

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