scholarly journals Sexual dysfunction in married female patients on antidepressants: A Cross Sectional Observational study from Patna medical college and hospital

2021 ◽  
Vol 12 (10) ◽  
pp. 129-134
Author(s):  
Vivek Pratap Singh ◽  
Abhishek Pratap Singh ◽  
Narendra Pratap Singh

Background: Clinicians and patients now have a broad variety of antidepressants to choose from, due to an ever-growing pharmacopoeia. However, one of the most significant considerations preventing antidepressant use is their side effects, one of which is sexual dysfunction. This issue has a negative impact on the patient’s quality of life which can contribute to clinical non-adherence in long-term therapies. Aims and Objectives: The objective of this research was to look into the characteristics of sexual dysfunction in married female antidepressant patients and patterns of sexual dysfunctions in female patients receiving antidepressants. Materials and Methods: It was Cross-sectional observational study. The study was conducted in the department of Psychiatry, Patna Medical College and Hospital at Patna.The Departmental Research Committee accepted the report, and 50 patients were enrolled after receiving written informed consent. Purposive sampling was used to pick the sample for the analysis, which had a cross-sectional study. The women contacted were in the outpatient psychiatric care of the department of Psychiatry and had been diagnosed with depressive disorder during the study period June 2018 to February 2019. Results: Seventy percent of patients were taking selective serotonin reuptake inhibitors (SSRIs), 20 % were taking tricyclic antidepressants (TCAs), and 10 % were taking other medications such as mirtazapine or desvenlafexine. Within six months, 44 % of patients were on therapy, and 22.0 % had been on treatment for more than two years. Patients taking Escitalopram (80 %) have less sexual activity than those taking Sertraline (66.7 %) or Fluoxetine (77.8 %), Patients observed a change in sexual activity in 58 percent of cases, a decrease in sexual desire in 70 % of cases (p=0.0009*), a slight decrease in 14 percent of cases, and a slight decrease in only 8 % of cases (p=0.0009). 18 % of patients reported a delay in orgasm, with 66 percent reporting a major delay, 8 % reporting a moderate delay, and 8 % reporting a slight delay (p=0.0001). Conclusion: Our findings indicate that sexual dysfunction is common in married female patients taking antidepressants, and that antidepressants affect both aspects of sexual functioning.

Author(s):  
Prachi Singh ◽  
Prashant Dubey ◽  
Shweta Yadav ◽  
Sachin Singh Yadav

Background: Abnormal Uterine Bleeding (AUB) is one of the commonest gynecological complain in reproductive age group. Menstrual abnormalities are commonly seen when there is any alteration in thyroid function. Objective of present study was to investigate the prevalence of AUB and to determine the menstrual pattern in cases with thyroid dysfunction.Methods: The present cross sectional observational study was conducted Teerthankar Mahaveer Medical College and Research Center Moradabad. Total 400 cases presenting with AUB were included in the study. Routine blood test, ultrasonography and thyroid function tests were done in these cases.Results: Among all the cases presenting with menstrual abnormalities 26% had hypothyroidism and 9% have hyperthyroidism and rest had euthyroid status. Menorrhagia (45.2%) and polymenorrhoea (37.5%) were commonest menstrual abnormality seen in cases with hypothyroidism. Most cases with hyperthyroidism presented with hypomenorrhoea (27.8%).Conclusions: Thyroid function abnormality is common in cases presenting with AUB and it gets relieved in correcting hormonal imbalance.


2015 ◽  
Vol 12 (1) ◽  
pp. 22-24 ◽  
Author(s):  
Sharmina Sayeed ◽  
Shamim Ara ◽  
Mesbahul Hoque ◽  
Zannatul Ferdous ◽  
Kanetarin Kashem

Context: The major duodenal papilla is one of the most fascinating papilla present at the duodenum attracting many gastroenterologists as they do endoscopic retrograde cholangiopancreatiography (ERCP) for diagnosis and treatment purpose of many diseases. Most of the textbooks of Anatomy describe that the summit of major duodenal papilla is situated posteromedially in the descending part of duodenum. Henceforth the present study was undertaken in 70 human duodenums to observe the location of major duodenal papilla. Materials & Methods: A cross-sectional observational study was conducted in the department of Anatomy, Dhaka Medical College, Dhaka from July 2010 to June 2011. Seventy postmortem human duodenums were collected from unclaimed dead bodies that were under examination in the morgue of department of Forensic Medicine and the department of Anatomy of Dhaka Medical College, Dhaka. Location of major duodenal papilla was observed and recorded. Results: The location of major duodenal papilla was observed in the medial wall of second part of duodenum in 78.6% specimens, in the posteromedial wall of second part in 15.7% cases and in the posteromedial wall of the junction between second and third part in 4.3% and absent in 1.4% duodenum. Conclusion: The location of major duodenal papilla varies in position. DOI: http://dx.doi.org/10.3329/bja.v12i1.22614 Bangladesh Journal of Anatomy, January 2014, Vol. 12 No. 1 pp 22-24


2020 ◽  
Vol 2 (2) ◽  
pp. 158-164
Author(s):  
Sandeep Grover ◽  
Natasha Kate ◽  
Eepsita Mishra ◽  
Ajit Avasthi

Aim: To assess the prevalence and typology of sexual dysfunction in female patients receiving antidepressant medications using the Arizona Sexual Experience Scale (ASEX). Method: A cross-sectional design was employed. A total of 71 married women with various psychiatric disorders receiving antidepressants for at least 3 months’ were evaluated on ASEX, Brief Adherence Rating Scale, Medication Adherence Questionnaire, and Global Assessment of Functioning (GAF) scale. Subjects with a history of sexual dysfunction prior to psychotropic intake, menopause, severe interpersonal relationship problems with spouse, or chronic medical illness were excluded. Results: The study sample had the mean age of 37.35 (SD: 6.82) years. More than four-fifth (80.2%) of patients had sexual dysfunction as per the ASEX. Using a cutoff score of 4 or more to define sexual dysfunction in various domains, decreased desire was seen in 81.7%, reduced arousal was seen in 80.3%, poor vaginal lubrication was seen in 76.1%, reduced satisfaction was seen in 57.7%, and reduced ability to reach orgasm was seen in 50.7%. Despite this, few patients (13.3%) discussed their sexual dysfunction with their treating psychiatrist. Sexual dysfunction did not influence the medication adherence. Conclusions: Sexual dysfunction is quite prevalent in female patients receiving antidepressant medications; however, this is not adequately discussed by the patient or the treating psychiatrist.


PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0253808
Author(s):  
Dhan Bahadur Shrestha ◽  
Nagendra Katuwal ◽  
Ayush Tamang ◽  
Agrima Paudel ◽  
Anu Gautam ◽  
...  

Background Medical students are more prone to burnout than the general population and students of other faculties due to the demanding nature of medical education with limited time and resources. Burnout has a negative impact on the academics and personal life of the students which can continue into their professional life and ultimately hamper patient care. The purpose of this study is to determine the prevalence of burnout among medical students of a medical college and find its association with age, gender, and year of study. Materials and methods This cross-sectional study was conducted among medical students of a medical college in Kathmandu, Nepal from 14 January to 7 March, 2021. Stratified sampling followed by a simple random sampling technique was employed to select study participants. Data was collected through a self-administered questionnaire using the English version of the Oldenburg Burnout Inventory adapted for students (OLBI-S) and analyzed in STATA version 15. Results The prevalence of burnout was found out to be 65.9% (n = 229). And of the remaining, 12.7% were exhausted, 11.4% were disengaged and 10.0% were neither exhausted nor disengaged. Burnout had no significant association with age in years, gender, and year of study. Conclusions This study shows an alarming prevalence of burnout in almost two-thirds of medical students. These results indicate the necessity of employing effective strategies by relevant authorities for the mental well-being of future physicians. Further multicenter prospective studies are required for a better understanding of the prevalence and associated factors of burnout.


2020 ◽  
Author(s):  
Khalid Alshehri ◽  
Raghad Al Thobaiti ◽  
Athar Alqurashi ◽  
Nada Algethami ◽  
Khaled Alswat

Abstract Background: Women with diabetes mellitus or thyroid disorders are at risk of sexual dysfunction. This study aimed to estimate the prevalence of female sexual dysfunction (FSD) in women with diabetes and/or thyroid disorders and the impact of disease control on the ASEX score.Methods: A cross-sectional study for female patients who had a routine clinic visit were included. The Arizona Sexual Experience Scale (ASEX) was used to evaluate for FSD. Those with a total score of ≥ 19 or scored ≥ 5 on any item or ≥ 4 on three items were considered to have FSD.Results: A total of 253 female patients with a mean age of 39.1 ± 7.3 years were included. Two-thirds of the participants have no FSD. More than half (57.7%) of the participants had a strong desire for sex, and about 20% of the participants were unsatisfied with their orgasm. Compared to those with no FSD, those with FSD had lower BMI (P = 0.375), more likely to have a master’s degree or higher (P = 0.117), diabetes (P = 0.879), hypothyroidism (P = 0.625), diabetes-related microvascular and macrovascular complications (P = 0.049), higher HbA1c, fasting glucose, and TSH (P = 0.731, P = 0.161, and P = 0.561, respectively), lower total cholesterol and LDL (P = 0.368 and P = 0.339, respectively), and exercise more regularly (P = 0.929). Conclusion: One-third (32.5%) of the study participants had a FSD. Those with type 1 diabetes had the highest ASEX scores. We detected non-significant negative correlations between total ASEX score and both BMI and TSH, as well as a non-significant positive correlation between total ASEX score and both HbA1c and fasting glucose value.


Author(s):  
Shumaila Parveen ◽  
Yaser M. Alahmadi ◽  
Faryal Adnan ◽  
Eshawa Darr ◽  
Ali Alalawi ◽  
...  

Objective: The objective of the current study is to determine the pattern of dermatological disorders and to find out their connection with different socioeconomically factors among students of the Medical College. Methodology: The Cross sectional observational study was carried out for the period of three months .The research instrument used was the well developed questionnaire. Results: The questionnaire was administered among total 350 students and the most participant age group was the > 22 and that was about 47.4% of the total sample size the more skin complication seen was the acne that was about 59.7%, in addition to this dandruff contributed very heavily to the hair complexities which makes about 35.7% of the sample. Conclusion: Skin infections especially the cosmetic are very common among the Medical students.


2021 ◽  
pp. 1-3
Author(s):  
Supriya Kumari ◽  
Surya Narayan ◽  
Kumudini Jha ◽  
Debarshi Jana

Background: Chronic pelvic pain (CPP)is cyclic or noncyclic, intermittent or constant discomfort in the pelvic region for at least 6 months. It is a common complaint in female adolescents that may be overlooked. Objective: To evaluate CPP in adolescents using transvaginal ultrasound (TVS) and laparoscopy. Study design: This is a prospective cross sectional observational study conducted at Obstetrics and Gynaecology Department of Darbhanga Medical College and Hospital, Laheriasarai, Bihar. A total of 100 adolescents with CPP were evaluated by TVS and laparoscopy and findings were analyzed. Results: The mean age of adolescents was 17 ± 3.5 the majority were parous (51%), rural (69%) and low social class (65 %). Diffuse pelvic pain was present in (62%), Dysmenorrheain (61%), deep abdominal and pelvic tenderness in (55% and 80% respectively). TVS was normal in (40%) andabnormalin (60%). Laparoscopic evaluation was normal in (29%)and abnormal in(71%) in the form of tubo- ovarian masses (19%),endometriosis (18%) ovarian cysts (9%), adenomyosis (8%), Adhesions (6%), PID and RVF uterus (4% for each), subserous fibroid and pelvic congestion (1% for each). sensitivity and specificity of TVS were (81.7% and 93.1% respectively). Positive and negative predictive values were 96.7% and 67.5% respectively. Kappa test between TVS and laparoscopy showed good agreement (kappa = 0.67). Conclusions: Good agreement was found between TVS and laparoscopy, however, laparoscopy is considered as a gold standard tool in evaluating adolescent CPP because of distinct advantages in terms of sensitivity and negative predictive value.


2017 ◽  
Vol 11 (2) ◽  
pp. 108-113
Author(s):  
Fadli Saputra ◽  
Roslizawaty Roslizawaty ◽  
Amiruddin Amiruddin ◽  
Nuzul Asmilia ◽  
T. Reza Ferasyi ◽  
...  

Tumor (TVT) aim of this study was to find out the prevalence and the factors were of Transmissible Venereal disease transmission on Dog Hunter in Payakumbuh. The study was conducted using a cross-sectional observational study (cross-sectional). Data collected through interviews by using questionnaires and observations of the condition of the Dog Hunter. The owners of hunter dogs were selected by purposive sampling. The obtained data were analyzed descriptively. Interviews were conducted with 110 people hunting dog owners with the total number of hunting dogs were observed as many as 300 individuals. The results showed that the prevalence rate of the Transmissible Venereal Tumor (TVT) disease on Dog Hunter in Payakumbuh is 1,33%. Factors the disease emergence were the mating habits of the dog were uncontrolled, the high levels of dogs sexual activity that was free to roam, the habitual of  sniffing and licking genitals of infected dogs TVT, and also does not apply the principles of biosecurity property.


Author(s):  
ASHWANI UMMAT ◽  
RANJODH JEET SINGH ◽  
SONIA KOCHHAR

Objective: The objective of the study is to analyze the prescription pattern of drugs for osteoarthritis (OA) in a north Indian medical college collaborated with a tertiary care hospital. Methods: An observational study was conducted on 300 patients diagnosed with OA in the department of orthopedics in collaboration with the department of pharmacology, and thus, prescription was collected as in a cross-sectional manner for 6 months and the same were analyzed in the Department of Orthopedics in tertiary care hospital collaborated with medical college. Results: The average age of patients participating in this present study was 56.46±7.4 years with affected age group of 46-60 years. 60 % of females were affected by osteoarthritis outnumbering male (40 %) patients in this present study. The most commonly involved joint was knee joint (87.33 %) in patients diagnosed with osteoarthritis followed by back (6.67 %) and hip joint (6%). The combination therapy (90 %) outweighed monotherapy (10 %) with preferred route of drug administration as oral route (90 %) followed by topical route (10 %). The average number of drugs prescribed for patients of osteoarthritis was 2.62±0.76. This present study concludes that NSAIDs (45.8%) were prescribed most commonly. However, the drug paracetamol was lesser prescribed and other drugs such as Diclofenac (27.22 %) and acetaminophen (34.44 %) most of all followed by Nimesulide (16.67 %), ibuprofen (13.33 %) and Rofecoxib/valdecoxib (8.33 %) were prescribed. Conclusion: This present study concludes that NSAIDs were most commonly prescribed as p-drugs while paracetamol was undermined prescribed.


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