scholarly journals Dermatological Manifestations in Diabetes Mellitus at NGMCTH Kohalpur

2017 ◽  
Vol 13 (2) ◽  
pp. 31-34
Author(s):  
Sumit Pandey ◽  
Pradip Mishra ◽  
Nirmala Sharma ◽  
Shyam B.K.

Background: Skin is the largest and most visible organ in the body. It undoubtedly determines to a great extent our appearance and plays  a  major  role  in  socio-sexual  communication.  More  than  one  third  of  diabetic  patients  have  some  type  of  dermatologic 1 manifestations during the course of their chronic disease . The association of certain skin diseases with diabetes mellitus has been 2 3 fairly well recognized with an incidence rate ranging from 11.4% to 66%.  At least 30% of patients with diabetes mellitus have some 4 5 type of cutaneous involvement during the course of their chronic disease.  Skin sugar levels run parallel to the blood sugar levels. Skin changes generally appear subsequent to the development of DM but may be the first presenting sign or even precede the 6 diagnosis by many years. Among the many skin manifestations in DM, none is pathognomonic of this disease. Cutaneous findings in DM can be classified into four categories: (1) skin disease with strong association and others with less distinct association with DM, (2) cutaneous infections, (3) dermatological disorders related to diabetic complications, and (4) skin conditions related to diabetes 7 treatments.Objectives: This study was undertaken to find out the pattern of Dermatological manifestations in Diabetes patients attending Nepalgunj Medical College Teaching Hospital, Kohalpur. Method and material: This is a hospital- based descriptive study conducted  in  the  Department  of  Dermatology,  Venereology  and  Leprology  of  Nepalgunj  Medical  College  Teaching  Hospital, Kohalpur  between   September 2013 to August 2014.  A total of 100 patients were included in the study. History and clinical examinations were performed and the data were recorded and analyzed. Results: The age of the patients ranged from 20 years to 85 years with the mean age of 51.7+12.13 years. The most common age groups were 46-55 years (36%) followed by 56-65 years (24.7%) and 36-45 years (17.3%), 66-75 years (9.3%), 76-85 years (12.7%). Among the 100 patients of diabetes ellitus, there were 44(44%) males and 56 (56%) females.  Among  the  cutaneous  disorders  commonly  associated  with  diabetes,  infections  were  the  most prevalent. 59(59%) out of 100 patients had skin infections.Conclusions: Patients with Diabetes can present with array of cutaneous disorders. Cutaneous infections formed the largest group of dermatoses in this study. Increased incidence of cutaneous infections mainly fungal and bacterial was noticed in majority diabetics emphasizing the need for more aggressive management of diabetes mellitus. Among infective dermatoses, fungal infections were the most common, with Candidal infections being more common than dermatophytosis.JNGMC Vol. 13 No. 2 December 2015, Page: 31-34

2020 ◽  
Vol 9 (3) ◽  
pp. 150-153
Author(s):  
Rita Kafle ◽  
Anuj Raj Kadel

Background: Dyslipidemia, a well-known major risk factor for coronary heart disease, is commonly associated with macro-vascular complications in patients with diabetes mellitus. Increased level of triglycerides and reduced levels of HDL cholesterol are common lipid abnormalities in diabetes. Objectives: The aim of the study was to study the prevalence and pattern of lipid abnormalities among diabetic patients attending general practice outpatient department in Kathmandu Medical College Teaching Hospital. Methodology: This is a descriptive cross-sectional study conducted in the Department of General Practice and Emergency of Kathmandu Medical College Teaching Hospital, Duwakot, Bhaktapur. Convenience sampling technique was used.After obtaining informed consent, 120 diabetic patients from January 2020 to March 2020 were included. The data collected was entered in the Statistical Package for the Social Sciences software and analyzed. Ethical clearance was taken from the Institutional Review Committee of Kathmandu Medical College.   Results:The average TC, HDL, TG and LDL level among the female participants were 186.18 mg/dl, 41.91 mg/dl, 194.63 mg/dl, 111.88 mg/dl respectively and 186.30 mg/dl, 38.80 mg/dl, 205.60 mg/dl, 125.80 mg/dl among the male participants respectively.Eighty-five (71%) patients had a low HDL level. Total cholesterol was found to be high in 38(32%) participants. LDL cholesterol was high in 77(64%) participants. The triglyceride level was high in 85(71%) participants. Conclusion: This study showed that some diabetic individuals have a lipid abnormality while others did not. This shines light on the importance of regular testing for lipid profile in diabetic individuals because we cannot reasonably predict when a patient will develop dyslipidemia.


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Kalpana Sharma ◽  
Govinda Dhungana ◽  
Shailendra Adhikari ◽  
Archana Bista Pandey ◽  
Muna Sharma

The prevalence of depression and anxiety disorders is common among people with diabetes mellitus. Coexistence of diabetes and depression/anxiety increases the risk of diabetes complications and reduces the overall quality of life. Hence, this study aimed to assess the depression and anxiety among patients with type 2 diabetes mellitus in Chitwan. Descriptive survey was carried out among 296 purposively selected clinically diagnosed type 2 diabetes patients admitted in the Chitwan Medical College Teaching Hospital from 15th June 2018 to 17th September 2019. Patients were interviewed using the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorders-7 (GAD-7). Data were analyzed using descriptive and inferential statistics. Of 296 diabetic patients, 48.6% were 60 years and above, 59.5% female and 61.5% literate; their common occupation was agriculture (38.2%) followed by household work (26.4%). Nearly two-thirds (62.8%) of diabetes patients had other chronic comorbid conditions. Depression and anxiety were observed among 57.8% and 49.7% of diabetes patients, respectively. While observing the severity, 27.4%, 19.6%, 8.4%, and 2.4% of patients had mild, moderate, moderately severe, and severe depression, respectively. Likewise, 24.7%, 20.3%, and 4.7% of patients had mild, moderate, and severe anxiety, respectively. Current living status, educational status, medicine adherence, satisfaction toward current treatment, and history of mental illness in the family were found to be significant factors associated with the anxiety of patients with diabetes. Further, educational status, smoking habit, satisfaction towards current treatment, and history of diabetes in family were the factors associated with depression. Prevalence of depression and anxiety is high among admitted patients with diabetes mellitus, and many factors are associated with it. Hence, regular screening services are essential along with diabetes management plan for timely identification and treatment of the vulnerable groups in the healthcare centers.


2020 ◽  
Vol 8 (1) ◽  
pp. 16
Author(s):  
Sruthi Kare ◽  
Vishwanath N. Reddy ◽  
Thejdeep Mahamkali

Background: India is one of the epicentres of the global diabetes mellitus pandemic. Rapid socioeconomic development and demographic changes, along with increased susceptibility for Indian individuals, have led to the explosive increase in the prevalence of diabetes mellitus in India over the past four decades. Diabetic Nephropathy is a common consequence of long-standing diabetes mellitus. The development of diabetic nephropathy has a dramatic increase on the morbidity and mortality of patients with diabetes. Objective of this study was to evaluate the prevalence of microalbuminuria in patients with diabetes mellitus patients.  Methods: This cross-sectional study was conducted on T 2 diabetes mellitus patients visiting medicine OPD of R L Jalappa hospital constituent hospital of Sri Deveraj Urs Medical College, Tamaka, Kolar from May 2016 to July 2016. A total of 60 type-2 diabetes patients were enrolled in the study.Results: Average duration of diabetes among study group was 8 years and most of the patients were between 6-10 years. In type 2DM patients, microalbuminuria and glycemic control have shown a significant linear correlation with duration of diabetes (p<0.05). Also, micro albuminuria has a significant correlation with increase in level of glycosylated haemoglobin.  Conclusions: The prevalence of microalbuminuria in diabetic patients was found to be high and being a developing country; there is a dire need that microalbuminuria and HbA1c testing should be done in both, newly diagnosed as well as already diagnosed type 2DM patients as an early marker of renal risk factor.


2020 ◽  
Vol 4 (2) ◽  
pp. 19-23
Author(s):  
Dhana Ratna Shakya ◽  
R Maskey ◽  
P Karki ◽  
SK Sharma

Background: Diabetes mellitus, a chronic disease, is frequently associated with sexual dysfunctions. Identification and management of these dysfunctions are important for overall wellbeing of the patient, though usually neglected. We lack data on this regard from Nepal. Objective: To estimate prevalence of psycho-sexual disorders (with emphasis on erectile dysfunction) in the patients with diabetes mellitus visiting ‘Diabetes clinic’ of a tertiary care teaching hospital in eastern Nepal. Method: It is a hospital-clinic based prevalence study. This study analyzed consecutive diabetes mellitus clinic patients’ response to self response questionnaires ‘Arizona Sexual Experience Scale’ (ASEX) for over all sexual dysfunction and ‘5- Item Version of the International Index of Erectile Dysfunction’ (IIEF-5) for erectile dysfunction. ‘Diabetes mellitus’ diagnosis was made based on the ADA guidelines 2010. Results: Among 100 male clinic diabetes patients, majorities were married, above age 50 years and all diagnosed as type 2 diabetes mellitus. Out of total, 48% had sexual dysfunction by the ASEX and many subjects had erectile dysfunction by the IIEF-5. Conclusion: Psychosexual dysfunctions, mainly erectile dysfunction are common among diabetic patients. Hence, assessment should include attention to sexual problems as well during management of diabetes mellitus.


Author(s):  
Ailton Santos Sena Júnior ◽  
Felipe José Aidar ◽  
Ana Mara de Oliveira e Silva ◽  
Fábio Bessa Lima ◽  
Jymmys Lopes dos Santos ◽  
...  

Diabetes Mellitus is one of the most prevalent chronic diseases in the world and one of its main features is chronic hyperglycemia. Among the therapeutic forms used to control the pathology are pharmacotherapy and the use of other alternatives such as regular exercise, which participates in glycemic control and the ingestion of plant extracts with antioxidant effects in the body. Among the different plants used, curcumin is a possible plant to be used to attenuate the hyperglycemic picture triggered by Diabetes Mellitus. Some studies suggest that this plant is antioxidant and hypoglycemic. The review aimed to know the antioxidant and hypoglycemic potential of curcumin supplementation in DM. The search was performed considering articles published between 2010 to 2019, in English and Portuguese, and a theoretical survey of relevant information was conducted in the main databases of scientific publications: Virtual Health Library and its indexed databases as Pubmed, LILACS, Scielo and Scientific Electronic Library Online. The associated use Turmeric and Physical Exercise demonstrated antioxidant, anti-inflammatory and hypoglycemic activity caused by Diabetes Mellitus. We may suggest that these are potential therapeutic ways to improve the quality and survival of diabetic patients.


2019 ◽  
Vol 9 (02) ◽  
Author(s):  
Karem Kdaer Karem ◽  
Saba Ibrahim Salih ◽  
Wafaa Kadhim Jassim

The second type of diabetes Mellitus is the most common type of diabetes, its represent about 90-95% of diabetes cases. In this disease, the response of the body to insulin does not occur properly in a condition known as insulin resistance. The diabetes may accompany with anemia because the hormone erythropoietin (EPO) which is produced by the kidneys is regulates red blood cell production and the Kidney has been damaged at several levels as a complication of diabetes, the complication range from diabetic nephropathy to chronic kidney disease. This study was conducted at the AL-Kafeel Hospital, Kerbala from October 2016 to December2016. The study included 60 adult patients with age range from 43-67 years and having diabetes mellitus type 2. Fasting blood sugar and Hb tests were made and accompanied with other information like age and duration of diabetes mellitus. The results show that 43% of diabetic patients had anemia and there is a strong negative connection between Hb levels and the duration of getting diabetes (p0.01). We conclude from this study that anemia is may developed in Type 2DM patients and the diabetic patients should be taken care of toprevent the development of diseases and other complications.


2018 ◽  
Vol 15 (1) ◽  
pp. 10-18
Author(s):  
Amit Thapa ◽  
Bidur KC ◽  
Bikram Shakya ◽  
Dipesh Kumar Yadav ◽  
Karjome Lama ◽  
...  

Corrigendum:The article published in Nepal Journal of Neurosciences 2018;15:10-18 by Amit Thapa et al was mistakenlypublished with wrong affi liation of some of the co-authors. The correct affi liation of the co-authors should read asBikram Shakya, MBBS, MS, MChLecturerDepartment of Neurological SurgeryKathmandu Medical College Teaching Hospital (KMCTH)Sinamangal, Kathmandu, NepalDipesh Kumar Yadav, MBBSMedical OfficerDepartment of Neurological SurgeryKathmandu Medical College Teaching Hospital (KMCTH)Sinamangal, Kathmandu, NepalKarjome Lama, MBBSMedical OfficerDepartment of Neurological SurgeryKathmandu Medical College Teaching Hospital (KMCTH)Sinamangal, Kathmandu, Nepal Abstract: We are witnessing changing patterns in stroke in our practice. Documenting changes in epidemiological profile are important for public health policy. We hereby present analysis of patients with stroke to stress upon the dynamics and update the improvement in their care. We retrospectively studied all patients with first time stroke presenting in Kathmandu Medical College Teaching Hospital during June 2012 till November 2015. Diagnosis was made on clinico-radiological basis with prospective follow up for at least 1 year from the event. Risk factors as well outcome in terms of Glasgow outcome score were studied. Statistical analysis was performed on SPSS. A total of 1017 patients of 16260 patients admitted to the hospital during the study period had first time stroke, a hospital based annual incidence of stroke of 64 per thousand admissions was hence calculated. Mean age was 55 years with 60.5% males. 503 patients (49.5%) had infarction with 20 patients having hemorrhagic conversion while 3 had TIA. 50.2% had hemorrhagic stroke. 56.7% females had ischemic stroke whereas 54.9% of males had hemorrhagic stroke (p=0.002). Common risk factors like HTN (54.7%), Smoking (41.5%), Alcohol (39.2%), dyslipidemia (34.1%) and DM (4.8%) were seen with stroke however, active smoker were more at risk of hemorrhagic stroke (p=0.000) while diabetic patients for ischemic stroke (p=0.000). Due to availability of neurosurgical services, 14.6% patient could undergo procedures like decompressive craniectomy, hematoma evacuation, CSF diversion procedures and carotid endarterectomy for stroke. 66.9% patients required surgical intervention within 48 hours of admission. We had 30 days mortality of 0.5% mortality in this series (majority in hemorrhagic stroke), however over 3 years duration of study mortality rose to 8.3% (majority in ischemic stroke). Almost 88.5% patients achieved mRS< Nepal Journal of Neuroscience, Volume 15, Number 1, 2018 11 2 over a period of 3 years. Persistent vegetative state was seen in 7.6% cases after 1 year. We observe a very high incidence of hemorrhagic stroke in general with higher than reported proportion of females being involved with ischemic stroke in our series. Most of the vegetative state conditions occurred in ischemic stroke patients however early mortality was common in hemorrhagic stroke. This change in pattern of stroke as well as need of surgical intervention mandates early involvement of neurosurgical services. Poor long term prognosis in ischemic stroke may be reversed by timely thrombolytic services and prevented by mitigating risk factors. Nepal Journal of Neuroscience 15:10-18, 2018


2016 ◽  
Vol 5 (2) ◽  
pp. 1-4
Author(s):  
Prashant Kumar Shah ◽  
Rupesh Kumar Shreewastav ◽  
Arambam Giridhari Singh

Background Diabetes Mellitus (DM) is one of the most common health problem characterizd by hyperglycemia. Type II Diabetes Mellitus is the most common one. Diabetic nephropathy is the most common clinical condition arises with in these patients which progressively leads to impairment in kidney’s function. Measurement of microalbumin in urine is the earliest dectactable stage of diabetic kidney disease.Material and Methods The total of 200 diabetic patients (112 males and 88 females) were enrolled and biochemical estimations including blood glucose level, serum creatinine, blood urea, urine albumin was conducted.Results Prevalance of microalbuminuria was 26 % in type II diabetic patients.Renal functions parameters like blood urea and serum ceratinine were higher in patients with positive microalbuminuria.60 % of diabetic patients are normoalbuminrics and rests 14% are proteinurics.Conclusion Various factors like increasing age, duration of diabetics, blood sugar level,blood urea, serum creatinine are the causes for microalbuminuria and proteinuria. Therefore, to rule out the early screening of diabetic kidney disease, DM patients should get routinely checked up with blood sugar level as well as renal profile test like serum creatinine, blood urea and albumin level in urine.Journal of Nobel Medical College Vol.5(2) 2016; 1-4


2019 ◽  
Vol 13 (Supl 1) ◽  
pp. S31
Author(s):  
Kelly Cristina Stéfani ◽  
Aldo Barbachan Rodrigues ◽  
Vinicius Quadros Borges ◽  
Gabriel Ferraz Ferreira ◽  
Leonardo Vinícius De Matos Moraes

Introduction: Diabetes mellitus (DM) has become a global public health problem. The concept of detection and management of diabetes mellitus in primary care centers is widely practiced in Brazil by the general practitioner. The aim of this study was to evaluate the efficacy of our educational program for diabetics for patients with diabetes mellitus and to determine the predictors of compliance. Methods: A cross-sectional prospective study was performed in a quaternary hospital where patients with diabetes were referred to the outpatient clinic of the diabetic foot group so that they were part of a multidisciplinary group (medical orthopedists specialists in foot and ankle, medical endocrinologists, physiotherapist and nurse) with a specific protocol for guidelines for foot care. Specialist orthopedic doctors of the foot and ankle completed the protocol and performed the specific physical examination. Results: Of the 578 diabetic patients, the mean age was 67 years, 69% were female, 53% used insulin to control the disease and the disease duration was 14 years. Obesity was diagnosed by calculation of the body mass index (BMI), and 85% patients were overweight. Evaluation of protective sensibility showed that 68% were significantly decreased, with sensation from the 4.0 g monofilament. One hundred and twenty seven patients required surgery resulting from clinical complications of the disease: 64 ulcers (Wagner classification 57% ulcers had a degree 1 Wagner classification, 63% affected forefoots), 54 Charcot arthropathies (52% Eichenholz in phase 3, 61% located in the mid-foot), and 9 cases of osteomyelitis. Fifty-three patients had one or more prior amputations at the time of their first appointment, mostly of the toes (66%). Conclusion: The costs related to the disease increased greatly with the appearance of complications, especially if there was a need for hospitalization and surgical treatment. The prevention of injuries with adequate glycemic control and the provision of protective shoes is essential.  


2019 ◽  
Vol 7 (2) ◽  
pp. 62-70 ◽  
Author(s):  
Devi Listiana ◽  
Effendi Effendi ◽  
Bela Indriati

Diabetes mellitus is a chronic disease that occurs due to the pancreas not being able to produce enough insulin or when the body cannot effectively use the insulin. The purpose of this study was to study the effectiveness of the provision of red betel leaf boiled water on reducing blood sugar levels of Diabetes Mellitus patients in the Saling Puskesmas District of Four Lawang in 2018. The design of this study was an experimental Quasy using The One Group Pretest - Postest Design, technique data collection using primary and secondary data. The population of this study were all Diabetes Mellitus patients in the Saling Community Health Center in July-August 2018, amounting to 16 people, sampling was done by accidental sampling. The results of the study, from 16 patients with diabetes mellitus there are 9 people (56.2%) with blood sugar levels less than 200 mg / dl. Wilcoxon Sign Rank test results obtained value Z = -3.517 with p = 0.000 0.05 means significant. So the two variables have different medians, there are differences in the GDS levels of Diabetes Mellitus patients before and after administration of red betel leaf decoction water. Conclusion, Red betel leaf decoction water is significantly effective in reducing blood sugar levels in patients with diabetes mellitus. It is expected that Puskesmas staff can increase public knowledge by counseling about red betel leaves as a Non-Pharmacological drug for patients with Diabetes Mellitus who do not experience complications. Keywords: Red Betel Leaf Decoction Water, Diabetes Mellitus, Blood Sugar Levels


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