scholarly journals Idiopathic Juxtafoveolar Telangiectasis Type 1A. A Case Report

2014 ◽  
Vol 2 (3) ◽  
pp. 38-40
Author(s):  
A Pandey ◽  
A Anand ◽  
A Singh ◽  
A Chandra
Keyword(s):  
Incidental Finding ◽  
Late Phase ◽  
Final Diagnosis ◽  
Chief Complaint ◽  
Treatment Modalities ◽  
Medical Sciences ◽  
Hard Exudates ◽  
Corrected Visual Acuity ◽  
Disease Entities ◽  
Medical Drug

No Abstract AvailableIdiopathic juxtafoveolar telangiectasisis a descriptive term for various disease entities presenting with incompetence, ectasia, and/or irregular dilations of the capillary network affecting only the juxtafoveolar region of one or both eyes. A 65 years male presented with the chief complaint of painless progressive diminution of vision in his left eye for 6 months' duration. Past ocular, surgical, medical, drug and family history was non contributory. The patient was non hypertensive and non diabetic. His best corrected visual acuity was 6/60 right eye and 6/36 left eye. Right eye, fundus was grossly normal whereas, on the left eye, few microaneurysms and circinate pattern of hard exudates were noticed on the perifoveolar region. Fundal reflex was dull and the foveal depression was absent indicating thickening. Fluorescein angiography showed clusters of telangiectatic vessels around exudates, hyperfluorescent dots of microaneurysms with a circinate pattern of leakage in the late phase. Optical coherence tomography showed macular thickening of 487 micrometer with cystoid changes. Injection Bevacizumab 0.2ml was given after final diagnosis of Left Eye Idiopathic Juxtafoveolar Telangiectasis Type 1A. Three types of idiopathic juxtafoveolar telangiectasis has been defined. Its pathophysiology is also less understood and the treatment modalities are not established yet.This case was an incidental finding, as these patients do not oftenly have profound diminution of vision, unless neovascularization has occurred and the clinical features too are very subtle.DOI: http://dx.doi.org/10.3126/jucms.v2i3.11827 Journal of Universal College of Medical Sciences Vol.2(3) 2014: 38-40

Predictors of Visual outcome in Post Fever Retinitis: A Retrospective Analysis

2021 ◽  
Author(s):  
Suchitra Biswal ◽  
Ankush Gondchawar ◽  
Ravishankar HN ◽  
Pradeep Sagar ◽  
P Mahesh Shanmugam ◽  
...  
Keyword(s):  
Visual Outcome ◽  
Treatment Modalities ◽  
Final Visit ◽  
Fundus Photograph ◽  
Hard Exudates ◽  
Corrected Visual Acuity ◽  
Unit Increase ◽  
Deposit Height ◽  
Best Corrected Visual Acuity ◽  
Final Visual Outcome

Abstract Purpose: To identify the predictors of final visual outcome in cases with post fever retinitis (PFR).Methods : This is a retrospective study of cases with diagnosis of post fever retinitis. Color fundus photograph and optical coherence tomography (OCT) parameters at presentation and final visit were analysed. Various factors at presentation [age, systemic illness, best corrected visual acuity (BCVA), area of retinitis and hard exudates, OCT parameters], at final visit (optic disc pallor, OCT parameters) and the treatment modalities used were correlated with BCVA at final visit.Results : Twenty four eyes of 16 patients with PFR were included in the study. Median BCVA at presentation was 6/60 and at final visit was 6/9. By multiple linear regression after adjusting for other variables, for every 1 unit increase in height of SRF at fovea at presentation, the value of final BCVA decreased by 0.001 unit. For every 1 unit increase in extent of EZ loss and subfoveal deposit height, the value of final BCVA decreased by 0.0001unit and 0.004 unit respectively.Conclusion: Height of SRF at presentation, extent of EZ loss and subfoveal deposit height at final visit were associated with poor final BCVA in PFR.

scholarly journals Thyroid cancer overdiagnosis and overtreatment: a cross- sectional study at a thyroid cancer referral center in Ecuador

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Paola Solis-Pazmino ◽  
Jorge Salazar-Vega ◽  
Eddy Lincango-Naranjo ◽  
Cristhian Garcia ◽  
Gabriela Jaramillo Koupermann ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Mortality ◽  
Incidental Finding ◽  
Cross Sectional Study ◽  
Anaplastic Carcinoma ◽  
Treatment Modalities ◽  
Sectional Study ◽  
Cross Sectional ◽  
Referral Center ◽  
Clinical Records

Abstract Background In contrast to the rapid increase in thyroid cancer incidence, the mortality has remained low and stable over the last decades. In Ecuador, however, thyroid cancer mortality has increased. The objective of this study is to determine possible drivers of high rates of thyroid cancer mortality, through a cross-sectional analysis of all patients attending a thyroid cancer referral center in Ecuador. Methods From June 2014 to December 2017, a cross-sectional study was conducted at the Hospital de Especialidades Eugenio Espejo, a regional reference public hospital for endocrine neoplasia in adults in Quito, Ecuador. We identified the mechanism of detection, histopathology and treatment modalities from a patient interview and review of clinical records. Results Among 452 patients, 74.8% were young adults and 94.2% (426) were female. 13.7% had a family history of thyroid cancer, and patients’ median tumor size was 2 cm. The incidental finding was 54.2% whereas 45.8% was non-incidental. Thyroid cancer histology reported that 93.3% had papillary thyroid cancer (PTC), 2.7% follicular, 1.5% Hurtle cells, 1.6% medullary, 0.7% poor differentiated, and 0.2% anaplastic carcinoma. The mean MACIS (metastasis, age, completeness, invasion, and size) score was 4.95 (CI 4.15–5.95) with 76.2% of the thyroid cancer patients having MACIS score less than or equal to 6. The very low and low risk of recurrence was 18.1% (79) and 62% (271) respectively. An analysis of 319 patients with non-metastatic thyroid cancer showed that 10.7% (34) of patients had surgical complications. Moreover, around 62.5% (80 from 128 patients with thyroglobulin laboratory results) of TC patients had a stimulated-thyroglobulin value equal or higher than 2 ng/ml. Overall, a poor surgical outcome was present in 35.1% (112) patients. Out of 436 patients with differentiated thyroid carcinoma, 86% (375) received radioactive iodine. Conclusion Thyroid cancer histological characteristics and method of diagnosis are like those described in other reports without any evidence of the high frequency of aggressive thyroid cancer histology. However, we observed evidence of overtreatment and poor surgical outcomes that demand additional studies to understand their association with thyroid cancer mortality in Ecuador.

scholarly journals Solitary Plasmacytoma in the Mandible Resembling an Odontogenic Cyst/Tumor

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Fatemeh Rezaei ◽  
Hesamedin Nazari ◽  
Babak Izadi
Keyword(s):  
Multiple Myeloma ◽  
Third Molar ◽  
Panoramic Radiograph ◽  
Final Diagnosis ◽  
Chief Complaint ◽  
Solitary Plasmacytoma ◽  
Oral Medicine ◽  
Bony Lesion ◽  
The Right ◽  
Rule Out

A 46-year-old male patient referred to Department of Oral Medicine, with the primary chief complaint of a painless swelling in the right side of mandibular. A panoramic radiograph revealed a well-defined, multilocular radiolucent bony lesion with thin and straight septa in the right side of mandible extending from distal of canine to mesial of third molar. Histological examination showed a solid proliferation of atypical plasmacytoid cells, which was indicative of plasmacytoma. A systemic workup for the final diagnosis was performed to rule out multiple myeloma.

scholarly journals A diagnostic and therapeutic challenge involving a case of dysphagia in association with cervical osteophytosis and a dental pain

2013 ◽  
Vol 04 (03) ◽  
pp. 334-336
Author(s):  
Rajani A Dable ◽  
Pradnya B Wasnik ◽  
Sunilkumar L Nagmode ◽  
Mukkaram Faridi Ali
Keyword(s):  
Musculoskeletal Disorders ◽  
Cervical Spondylosis ◽  
Dental Pain ◽  
Chief Complaint ◽  
Occupational Hazards ◽  
Direct Connection ◽  
Therapeutic Challenge ◽  
Dental Origin ◽  
Disease Entities

ABSTRACTHerein, presenting a case of a 42-year-old female with the chief complaint of dysphagia. The problem was assumed to be of dental origin, due to the onset of dental pain followed by dysphagia. A cervical radiograph revealed the presence of osteophytic lipping which proved to be the cause of dysphagia. Confusing and overlapping disease entities showing similar symptoms need thorough investigation. Dysphagia related to cervical spondylosis may have a direct connection with the person′s occupation. Dentistry is considered a potentially hazardous occupation with regard to musculoskeletal disorders. However, additional studies are required to understand the occupational hazards faced by dentists.

scholarly journals Medical Sciences’ Students Responses During the Late Phase of the COVID-19 Pandemic in Iran: A Comprehensive Investigation of the Risk Perception and Information Exposure

2021 ◽  
Author(s):  
Mahan Shafie ◽  
Mahsa Mayeli ◽  
Hamed Hosseini ◽  
Mahnaz Ashoorkhani
Keyword(s):  
Risk Perception ◽  
Perceived Risk ◽  
Late Phase ◽  
Population Level ◽  
Sources Of Information ◽  
Medical Sciences ◽  
Online Questionnaire ◽  
Significant Difference ◽  
Information Exposure ◽  
Risk Patients

COVID-19 pandemic obligated applying population-level behavioral modifications to effectively prevent the spread of the disease. This necessitated investigating those measures that determine population behavior. Herein we have studied risk perception and information exposure that are among those determinants in Iran. 402 cases from medical sciences students were enrolled during the last week of September 2020. Using an online questionnaire, risk perception and sources of information about COVID-19 were investigated. Although most students considered COVID-19 preventable, merely a few considered the disease curable. A higher risk was perceived concerning the families compared to themselves. Moreover, most of them believed the prognosis good even in high-risk patients. Social media was the most informative source used; however, health professionals were considered the most reliable. The risk perception was equal between those diagnosed with COVID-19 or had a family member diagnosed compared to those without such exposure in most questions. Also, no significant difference was observed in risk perception between those students with serious underlying medical conditions and those without one regarding most items. Lastly, major and grade were the most significant demographic contributors to the risk perception. Moderate risk was perceived overall among the cases in which major and grade were the only remarkable demographic contributors. Unexpectedly, underlying medical history was not significantly correlated with the perceived risk. Lastly, previous COVID-19 exposure merely altered the curability and preventability perception.

scholarly journals Epidermolysis Bullosa Acquisita in Children: Case Series

2019 ◽  
Vol 18 (1) ◽  
pp. 56-64
Author(s):  
Nikolay N. Murashkin ◽  
Leonid A. Opryatin ◽  
Alexander I. Materikin ◽  
Eduard T. Ambarchyan ◽  
Roman V. Epishev ◽  
...  
Keyword(s):  
Epidermolysis Bullosa ◽  
Case Series ◽  
Basal Membrane ◽  
Final Diagnosis ◽  
Epidermolysis Bullosa Acquisita ◽  
Type Vii Collagen ◽  
Bullous Dermatosis ◽  
Medical Drug ◽  
Line Drug

Background. Epidermolysis bullosa acquisita (EBA) is chronic disease accompanied with subepidermal blistering on skin and mucous membranes as a result of autoimmune aggression to type VII collagen. EBA diagnostics in children is complicated due to similarity of clinical presentation with other bullous dermatosis in children.Clinical Case Description. The description of three clinical cases of EBA in children is provided. It is shown that for establishing the diagnosis it is necessary to estimate clinical evidence and to define the depth of blisters according to the results of histological examination of skin biopsy sample. Determination of IgG deposition positions relatively to the skin basal membrane due to performed indirect immunofluorescence test helps us to establish final diagnosis and specify patient management. Medical drug Dapsone was used in children with EBA, it has shown to be effective and safe to use as the first-line drug in management of such patients.Conclusion. The algorithm for EBA differential diagnosis with other bullous dermatosis in children is provided. Successful results of medical treatment are described. 

A PROSPECTIVE STUDY TO COMPARE THE EFFICACY OF THREE TREATMENT MODALITIES ON BENIGN BREAST DISEASE VIZ. EVENING PRIMROSE OIL (EPO), DANAZOLAND CENTCHROMAN

2021 ◽  
pp. 22-24
Author(s):  
Abhishek Chaudhary ◽  
Prem Prakash ◽  
Yasir Tajdar ◽  
Nadeem Ahmad
Keyword(s):  
Prospective Study ◽  
Premenopausal Women ◽  
Breast Disease ◽  
Treatment Modalities ◽  
Breast Pain ◽  
Medical Sciences ◽  
Evening Primrose ◽  
Cancer Breast ◽  
Breast Lumps ◽  
A Prospective Study

Background: Breast pain among women, with or without lump is common complaint and a cause of signicant anxiety and fear of breast cancer. Breast feeding is additionally one of the reasons for non-cyclic pain, brocystic breast disease is otherwise called broadenosis. Material and Methods:This is prospective study in the Department of General Surgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar. Conclusion: Centchroman is a selective anti estrogen effective in the treatment of brocystic disease. Centchroman is effective in reducing the sizes of breast lumps, providing relief from mastalgia and in curing cyclical and noncyclical breast pain in the premenopausal women.

THE CLINICAL IMPLICATIONS OF HEMOGLOBIN STRUCTURE

PEDIATRICS ◽  
1963 ◽  
Vol 31 (5) ◽  
pp. 780-785
Author(s):  
Park S. Gerald
Keyword(s):  
Incidental Finding ◽  
Chief Complaint ◽  
Clinical Implications ◽  
Dominant Inheritance ◽  
Successful Completion ◽  
Contributing Factors ◽  
Peripheral Neuritis ◽  
Paternal Aunt ◽  
The Many ◽  
And Training

I FEEL DEEPLY HONORED to be named as one of the recipients of the 1962 Mead Johnson Awards for research in pediatrics. I am grateful for this opportunity to express my indebtedness and gratitude to the many who have aided me, and especially to my sponsor, Dr. Louis K. Diamond. His unwavering confidence and unselfish support were major contributing factors toward the successful completion of these research efforts. Lack of time prevents me from giving an adequate list of those other teachers and associates who contributed significantly toward my research efforts and training, but time can never be so short as to prevent me from mentioning my stimulating and energetic co-worker, Dr. Mary Efron. I have saved to the last, mention of my wife, as she has so often cheerfully been the vital silent partner of experiments that seemed always to last "just a little longer" than I expected. In order to make this a coherent presentation, I am going to dwell solely upon the "Hb M diseases." This group of hemoglobinopathies is characterized by the presence of cyanosis in several generations of a given family, being transmitted as if determined by the presence of a single abnormal gene (i.e., "dominant" inheritance). In the first family of this disorder that came to our attention, the cyanosis was an incidental finding in a child whose chief complaint was an obscure peripheral neuritis. There seemed to be little relation between the peripheral neuritis and the cyanosis, since the child's brother, father, paternal aunt and other relatives also were cyanotic (Fig. 1), although lacking any neuritis.

Hyperreflective cystoid spaces in diabetic macular oedema: prevalence and clinical implications

2020 ◽  
pp. bjophthalmol-2020-317191
Author(s):  
Aude Couturier ◽  
Valerie Mane ◽  
Carlo Alessandro Lavia ◽  
Ramin Tadayoni
Keyword(s):  
Macular Oedema ◽  
Optical Coherence Tomography Angiography ◽  
Diabetic Macular Oedema ◽  
Functional Improvement ◽  
Vascular Endothelial ◽  
Hard Exudates ◽  
Corrected Visual Acuity ◽  
The Mean ◽  
Endothelial Growth Factor

AimsTo analyse the prevalence and evolution of hyper-reflective cystoid spaces with decorrelation signal detected using optical coherence tomography angiography (OCTA) in diabetic macular oedema (DMO).MethodsA retrospective study of consecutive eyes with DMO imaged using OCTA over a 1-year period was conducted. All eyes with hyper-reflective cystoid spaces at baseline and at least 3 months of follow-up were included in a longitudinal analysis.ResultsThe prevalence of hyperreflective cystoid spaces with decorrelation signal was of 37% (61/165) in DMO eyes. Hyperreflective foci within hyperreflective cystoid spaces were observed in 85% of eyes. The longitudinal study included 33 eyes (10 observed and 23 treated with intravitreal anti-vascular endothelial growth factor), with a median follow-up of 15 months. The hyperreflective cystoid spaces resolved in 85% of eyes. The mean best-corrected visual acuity remained stable during the follow-up, even in the eyes achieving a resolution of the hyperreflective cystoid spaces. Hard exudates appeared in the area of resolved hyperreflective cystoid spaces in 33% of eyes.ConclusionHyperreflective cystoid spaces detected by OCTA affected more than one-third of the DMO eyes. Their disappearance was not associated with any functional improvement and led to the formation of new hard exudate deposits in about one-third of the eyes.

Surgical management of pterygium in a rural hospital using bare sclera versus conjunctival autograft technique

2017 ◽  
Vol 5 (5) ◽  
pp. 2076
Author(s):  
Dinesh P. ◽  
Sundip Shenoy ◽  
Nidhi Pandey ◽  
Pavan Kumar Reddy D.
Keyword(s):  
Visual Acuity ◽  
Connective Tissue ◽  
Medical Sciences ◽  
Visual Axis ◽  
Recurrence Rates ◽  
Conjunctival Autograft ◽  
Corrected Visual Acuity ◽  
Department Of Ophthalmology ◽  
Best Corrected Visual Acuity ◽  
Conjunctival Autografting

Background: Pterygium is defined as a triangular fibrovascular subepithelial ingrowth of degenerative bulbar conjunctival tissue over limbus onto the cornea. Commonly seen among farmers, fishermen, stone cutters and welders. Both blue and ultraviolet light have been implicated in its causation. Histologically the true Pterygium shows elastotic degeneration of the subconjunctival connective tissue. Pterygium warrant treatment when they encroach the visual axis, induces significant astigmatism or become cosmetically bothersome. My present study was undertaken to evaluate the efficacy, safety and recurrence rates of conjunctival autograft and bare sclera techniques in treatment of progressive true pterygium in a rural hospital.Methods: The prospective study was done in the Department of Ophthalmology, Adichunchanagiri Institute of Medical Sciences, B.G Nagara, Mandya District, Karnataka, India. The study was conducted for a period of 18 months. About 70 patients who presented with progressive pterygium were included in the study.Results: In our study pterygium recurred in 10 cases (14.28%), among which pterygium recurred in 8 cases (22.85 %) using bare sclera technique and in 2 patients (5.71%) using conjunctival autograft technique, best corrected visual acuity remained stable in 37 cases (52.85 %), improved in 33 cases (47.14 %) and worsened in none (0%) of the cases.Conclusions: Conjunctival autografting is a safe and effective procedure in the management of pterygium. The recurrence rate following limbal conjunctival autografting is significantly lower than that following primary conjunctival closure by bare sclera technique.

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