Effects of selected herbal supplements in persons with type 2 diabetes

2020 ◽  
Vol 22 (4) ◽  
pp. 254-259
Author(s):  
Gajendra Prasad Rauniyar ◽  
R Sinha ◽  
DR Pandey ◽  
K Chapagain ◽  
R Maskey
Keyword(s):  
Lipid Profile ◽  
Blood Sugar ◽  
Serum Triglyceride ◽  
Multiple Comparisons ◽  
Lipid Lowering ◽  
Total Serum ◽  
Fenugreek Seeds ◽  
Group I ◽  
Significant Difference ◽  
Post Hoc

Diabetes mellitus is a metabolic abnormality leading to an increase in the plasma concentration of glucose and is a major cause of stroke and peripheral circulatory disorders. Momordica charantia (MC), commonly known as bitter gourd/Karela, and Trigonella foenum-graecum (TFG) (fenugreek/Methi) have several medicinal values like anti-diabetic, lipid-lowering property, anti-oxidant activity, anti-inflammatory, and anti-mutagenic activity. This is an open-label, four-parallel-group, prospective interventional clinical trial with a total number of 48 patients enrolled in the study and divided into four equal groups (12 in each group) viz; Group I (allopathic drug), Group II (allopathic drug and Karela (MC), Group III (allopathic drug and Methi (TFG) and Group IV (allopathic drug, methi, and karela). Blood sugar and lipid profile were measured at day 0 and day 90. One way ANOVA test was applied to find the significant difference between the groups and Tukey HSD post hoc test was applied for multiple comparisons among the four groups with probability p-value 0.05%. Multiple comparisons by post-hoc analysis between groups on day 90 showed a significant reduction of fasting blood sugar by 19.0% (p = 0.021), postprandial blood sugar by 35.0% (p= 0.001), total serum cholesterol by 14.0% (p= 0.000), serum triglyceride by 21.0% (p=0.000), and serum LDL cholesterol by 17.0% (p= 0.000)ingroup receiving Karela and fenugreek seeds supplementation. Whereas serum HDL cholesterol on the 90th day was higher in the group by 10.0% (p=0.015) receiving only fenugreek seeds as a supplementation. Fenugreek and karela, when given as a supplement, have a beneficial effect on blood sugar and lipid profile.

scholarly journals The Comparative Effectiveness of Phaleria macrocarpa (Scheff.) Boerl. Pericarp Ethanol Extract and Metformin in Reducing Blood Sugar Levels and Ameliorating the Langerhans Islets Degeneration in Diabetic Rat Models

2020 ◽  
Vol 17 (1) ◽  
pp. 241
Author(s):  
Eman Sutrisna ◽  
Qurrotu Aini ◽  
Ika Murti Harini ◽  
Nur Signa Aini Gumilas ◽  
Mustofa Mustofa ◽  
...  
Keyword(s):  
Blood Sugar ◽  
Ethanol Extract ◽  
Diabetic Rat ◽  
P Value ◽  
Test Results ◽  
Langerhans Islets ◽  
Group I ◽  
Significant Difference ◽  
Sugar Levels ◽  
Post Hoc

Phaleria macrocarpa (Scheff.) Boerl. has been widely used in the treatment of diabetes mellitus but its effectiveness is still inconclusive so it needs to be compared with standard drugs such as metformin. This study aims to analyze the effects of P. macrocarpa fruit extracts on blood sugar levels and the repairing of the pancreatic Langerhans islets of diabetic rat models. The study was conducted experimentally by pre and post-test design with a control group. Thirty white rats were divided into 6 groups. All rats were treated with 40 mg/200 g BW of streptozotocin (STZ) to induce hyperglycemia, except group I. Group II as a negative control was given with aquadest. Group III, IV, and V were given with ethanol extract of P. macrocarpa pericarps at doses of 200, 250, and 300 mg/200 g BW/day, respectively. Group VI was given with metformin at a dose of 150 mg/200 g BW/day. On the 22nd day of treatment, blood specimens were taken for examination of fasting blood sugar levels and pancreatic organs were analyzed for histopathological examination of the islets of pancreatic Langerhans. The data were statistically analyzed with α<0.05; CI95%. Paired sample t-test results showed a significant decrease in blood sugar levels before and after treatment in group V (p-value=0.048). One way anova and post hoc Least Significant Difference (LSD) test results showed a significant difference in mean blood sugar levels after the final treatment between groups I and II (p-value=0.013), I and III (p-value=0.004), I and IV (p-value=0.002), I and VI (p-value=0.000), II and VI (p-value=0.031), and V with VI (p-value=0.005); one way anova and post hoc LSD test results showed a significant difference in the mean area of islets of pancreatic Langerhans between group I and all treatment groups (p-value=0.000), II with V and VI (p-value=0.000 and 0.009), III with V and VI (p-value=0.000 and 0.001), and IV with V (p-value=0.003). It can be concluded that the extract of P. macrocarpa pericarps showed a hypoglycemic effect and repaired the damage in Langerhans islets of STZ-induced rat in a dose-dependent manner.

scholarly journals Short-term Effect of Garlic Extract on Patients with Dyslipidemia

2019 ◽  
Vol 21 (4) ◽  
pp. 301-305
Author(s):  
A Limbu ◽  
GP Rauniar ◽  
SK Sharma ◽  
DR Panday ◽  
BK Shah ◽  
...  
Keyword(s):  
Serum Cholesterol ◽  
Ldl Cholesterol ◽  
Serum Triglyceride ◽  
Hdl Cholesterol ◽  
Lipid Lowering ◽  
Total Serum ◽  
Total Serum Cholesterol ◽  
P Value ◽  
Vldl Cholesterol ◽  
Significant Difference

Dyslipidemia is a metabolic abnormality leading to a persistent increase in the plasma concentration of cholesterol and triglycerides. Dyslipidemia is known to promote atherosclerosis. It is a complex disease and is a major risk factor for adverse cardiovascular events. Allium sativum commonly known as garlic has been found to have several medicinal value including, lipid-lowering property, blood pressure decreasing, anti-diabetic, anti-cancer and anti-oxidant activity. It was a double-blind, two-parallel-group, prospective interventional clinical trial. Total no of 112 patients were enrolled in the study and divided into two equal groups (56 in each group) viz; Group 1 (Lasuna TM) and Group 2 (placebo). Lipid profile was measured at day 0 and 90. Independent–sample‘t’ test was applied to find out the significant difference between the two groups, P-value being 0.05. The mean difference Total Serum Cholesterol, Serum Triglyceride, Serum LDL Cholesterol and Serum VLDL cholesterol on day 0 was nonsignificant with p being 0.539, 0.811, 0.230, 0.770 and 0.811 and on 90th day was significantly lower in group taking garlic with p being 0.001, 0.014, 0.003 and 0.008 respectively whereas Serum HDL cholesterol on 90th day was significantly higher in group taking garlic with p being 0.001. Garlic, when given as supplement decreases Total Serum Cholesterol, Serum Triglycerides, Serum LDL Cholesterol and Serum VLDL Cholesterol and on the other hand it increases Serum HDL Cholesterol.

scholarly journals A comparative study of atorvastatin and rosuvastatin on lipid lowering efficacy in hyperlipidemic patients

2018 ◽  
Vol 11 (1) ◽  
pp. 17
Author(s):  
Samia Haque Tonu ◽  
Zesmin Fauzia Dewan ◽  
Nargis Akhter ◽  
Sajal Krishna Banerjee
Keyword(s):  
Lipid Profile ◽  
Serum Triglyceride ◽  
Lipid Lowering ◽  
Serum Triglyceride Level ◽  
Intergroup Difference ◽  
Atorvastatin Group ◽  
Significant Difference ◽  
Rosuvastatin Group ◽  
Significant Change ◽  
Lipid Lowering Effect

<p class="Abstract">The aim of the present study was to compare the lipid lowering effect of atorvastatin and rosuvastatin in patients (n=52) with hyperlipidemia. Patients were assigned to atorvastatin 10 mg or rosuvastatin 5 mg daily for 8 weeks. The blood was collected at baseline and after intervention to measure serum lipid profile. The level of serum total cholesterol in both atorvastatin and rosuvastatin groups was significantly reduced after intervention (p&lt;0.00001 and p&lt;0.00001 respectively) but no statistically significant difference (p=0.503) was observed between the two statin-treated groups. The reduction of serum triglyceride level was also significant (p=0.046 in atorvastatin group and p=0.0006 in rosuvastatin group). No significant difference was observed between the two groups (p=0.312). The serum LDL-C level was reduced significantly in both atorvastatin group (p&lt;0.00001) and rosuvastatin group (p&lt;0.00001). Again no statistically significant difference (p= 0.749) was observed between the two groups. No significant change was observed in the serum HDL level. Intergroup difference was not significant (p= 0.721). The present study indicates that, both atorvastatin and rosuvastatin improve the lipid profile but no significant change was observed between the two groups.</p>

Role of Cord Blood Carboxyhemoglobin in Detecting Significant Hyperbilirubinemia in Term Neonates with ABO Alloimmunization

2021 ◽  
Author(s):  
Mahir Tıraş ◽  
Emrah Can ◽  
Şahin Hamilçıkan
Keyword(s):  
Cord Blood ◽  
Total Serum ◽  
Healthy Controls ◽  
Term Neonates ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Group Ii ◽  
Positive Direct ◽  
Severe Hyperbilirubinemia

Objective This study aimed to assess whether cord blood carboxyhemoglobin (COHb) levels in jaundiced term neonates with and without a positive direct Coombs test (DCT) and in healthy controls could be used as a predictor of severe hyperbilirubinemia. The percentage of cord blood COHb should be higher among neonates with Coombs-positive ABO hemolytic disease than among those with Coombs-negative ABO incompatibility and higher than that of ABO-compatible control neonates. Study Design This cross-sectional descriptive study of 198 term neonates comprised three subgroups: group I featured 68 DCT-positive ABO-incompatible neonates (ABO + DCT), group II featured 60 DCT-negative ABO-incompatible neonates with hyperbilirubinemia (ABO–DCT), and group III featured 70 healthy controls. COHb was determined by an OSM3 hemoximeter. Results Group I differed from groups II and III for cord blood bilirubin, cord blood hemoglobin, and cord blood hematocrit. Groups I and II had higher mean total serum bilirubin (TSB) levels than group III, while there was no difference in the mean TSB levels between groups I and II. There was no significant difference between the COHb group means for groups I, II, and III (p = 0.98). The area under the receiver operating characteristic curve calculated for group I/group III and group II/group III were found to be 0.62 and 0.54, respectively. Conclusion COHb levels did not prove to be superior to the DCT for predicting the risk of developing severe hyperbilirubinemia in term neonates. Key Points

scholarly journals AB0875-HPR NON-PHARMACOLOGICAL AND PHARMACOLOGICAL APPROACHES TO THE MANAGEMENT OF PATIENTS WITH OSTEOARTHRITIS AND LIPID METABOLISM DISORDERS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1461.1-1461
Author(s):  
T. Rogatkina ◽  
O. Korolik ◽  
V. Polyakov ◽  
G. Kravtsov ◽  
Y. Polyakova
Keyword(s):  
Physical Activity ◽  
Cardiovascular Disease ◽  
Lipid Metabolism ◽  
Lipid Profile ◽  
Fat Mass ◽  
Prognostic Significance ◽  
Lipid Lowering ◽  
Lipid Lowering Therapy ◽  
Lipid Metabolism Disorders ◽  
Group I

Background:Attention is drawn to the frequent combination of osteoarthritis (OA) with cardiovascular disease. Non-specific inflammation plays a significant role in the pathogenesis of OA and atherosclerosis. Limiting the physical activity of patients with OA is an additional important factor aggravating the course of cardiovascular disease (CVD). Chronic pain syndrome, causing a neuroendocrine response, is often the cause of the development of complications of atherosclerotic disease. Dyslipidemia is the main cause of atherosclerosis and vascular thrombosis.Objectives:To study variants of lipid metabolism disorders in female and male patients of different age groups with osteoarthritis.Methods:Case histories of 90 patients with OA were analyzed. The average age of patients was 63.27 ± 11.31 years. The average body mass index (BMI) is 39.8 ± 3.2. All patients underwent questionnaires, general clinical and biochemical blood tests with lipid profile determination, anthropometry, bioimpedansometry, and the main metabolic rate assessment using indirect calorimetry in dynamics (at the beginning of the study and after 3 months).Results:Burdened heredity for obesity, arterial hypertension (AH), diabetes mellitus (DM) was revealed. AH was diagnosed in 76 patients (84.4%), type II diabetes in 17 (18.9%), dyslipidemia and hypercholesterolemia in 56 (62.2%). Statins were taken by 43 patients (47.8%) - group I patients, which is associated with low adherence to therapy, group II included patients who did not initially take statins or stopped taking them at least 6 months before inclusion in the study.Against the background of diet therapy and physiotherapy exercises, BMI (R0.99; p <0.05), fat mass (R0.95; p <0.05) significantly decreased, lipid profile normalization was noted: total cholesterol (R0.66; p <0 .05), LDL (R0.69; p <0.05), HDL (R0.95; p <0.05), TG (R0.57; p <0.05), AST decreased (R0.64; p <0.05) and ALT (R0.76; p <0.05) in both groups of patients, regardless of lipid-lowering therapy. A decrease in fat mass correlated with TG levels (R0.51; p <0.05), an increase in skeletal muscle mass (R0.60; p <0.05), lean mass (R0.72; p <0.05), and active cell mass (R0.59; p <0.05). The lipid profile in the I group of patients was significantly better before and at the end of the study. Long-term effects have not been investigated due to the short duration of the study.Conclusion:In patients with OA, a high frequency of concomitant diseases of the cardiovascular system, lipid metabolism disorders was found. Non-drug therapy has a positive effect on the lipid profile and the level of transaminases. The decrease in body weight due to loss of fat mass reliably correlates with the level of TG. Timely use of statins contributes to the normalization of the lipid profile, reduces the risk of cardiovascular disease in patients with OA. It is necessary to study lipid profile disorders in patients with OA with recommendations for lifestyle modification (diet, physical activity), and if necessary, prescribe lipid-correcting therapy.References:[1]E. Simakova, B. Zavodovsky, L. Sivordova [et al]. Prognostic significance of lipid disorders markers determination in pathogenesis of osteoarthritis. Vestnik Rossijskoj voenno-medicinskoj akademii. 2013. No. 2 (42). P.29-32.[2]Zavodovsky B.V., Sivordova L.E. Prognostic significance value of definition of leptin level determination in osteoarthritis. Siberian Medical Journal (Irkutsk). 2012; 115(8):069-072.Disclosure of Interests:None declared

scholarly journals Coenzyme q10 is potentially usedto improve lipid profile in diabetic hypercholesterolemia-induced periodontitis in the coastal area

2018 ◽  
Vol 47 ◽  
pp. 07006
Author(s):  
Saryono Saryono ◽  
Hesti Devinta ◽  
Abdul Haris Budi Widodo ◽  
Arif Imam Hidayat
Keyword(s):  
Lipid Profile ◽  
Coenzyme Q10 ◽  
Coastal Area ◽  
Positive Control ◽  
Atherogenic Index ◽  
Control Group ◽  
Treatment Groups ◽  
Significant Difference ◽  
Pap Method ◽  
Post Hoc

Contaminated water often affects the occurrence of periodontitis in the coastal area. The diabetic hypercholesterolemia-induced periodontitis in Indonesia is very high. The use of coenzyme Q10 to treat this disease has never been investigated yet. Therefore, this study aimedto analyze the effect of coenzyme Q10 on the lipid profile of diabetic hypercholesterolemia-induced periodontitis.Twenty four rats were randomized into 6 groups (G1-G6). The groups (G1-G3) are healthy, negative and positive control group respectively. The treatment groups (G4-G6) are diabetic hypercholesterolemia-induced rats given coenzyme q10 dose of 13,5; 27 and 54 mg/kg respectively. Rats were induced by periodontitis, hypercholesterolemia and diabetes mellitus. Coenzyme Q10 was administered orally using 2 mL gastric tube once a day for 14 days. Lipid profile including triglycerides, HDL, and atherogenic index (IA) was measured enzymatically by the CHOD-PAP method. Data were analyzed by one-way ANOVA test and followed by the Least Significant Difference (LSD) post hoc test.Coenzyme Q10 with a dose of 54 mg/kgis effective in lowering triglyceride, and atherogenic index and increasing HDL level in diabetic hyperlipidemia-induced periodontitis rats model. This research supports the potential effects of coenzyme Q10 supplementation to improve lipid profile in diabetic hypercholesterolemia-induced periodontitis in the coastal area.

scholarly journals The Effect of Smoking on the Lipid Profile of Inhabitant Smokers of Hasilpur, District Bahawalpur, Pakistan

2020 ◽  
Vol 10 (2) ◽  
pp. 82-86
Author(s):  
Mushtaq Hussain Lashari ◽  
Sumbel Sumera ◽  
Umer Farooq ◽  
Zia Ur Rehman ◽  
Nuzhat Sial ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Serum Triglyceride ◽  
Mean Value ◽  
Heavy Smoker ◽  
Control Group ◽  
Mean Values ◽  
Significant Difference ◽  
The Mean ◽  
Control Light ◽  
Heavy Smokers

Background: Health problem are culturally associated with smoking in developing countries. Many hazardous chemicals are taken up by direct or passive smoking causing lipid peroxidation resulting in oxidative stress. Objectives: To estimate the occurrence of smoking and its effects on the lipid profile in populations of Hasilpur, Pakistan. Methodology: The current study was conducted from April - August 2014. Out of 247 apparently healthy subjects of both genders (male=220; female=27), 134 were smokers and 113 were non-smokers. In order to analyze lipid profile, blood samples were collected in early morning hours from the selected members who were asked to fast all night. By using Chem-100 chemistry analyzer, cholesterol, triglyceride, HDL, LDL and VLDL were analyzed. Results: The overall prevalence of smokers was 54.25%. The results showed 60.9% prevalence in males and 0% in females. The mean value of serum triglyceride in control, light smokers and heavy smokers was 147.4±11.7mg/dl, 190.8±41.4 and 205.3±29.7mg/dl, respectively. The results of cholesterol in control, light smokers and heavy smokers were 147.38±7.99mg/dl, 136.8 ±12. 8mg/dl and 173.44±8.63mg/dl, respectively. There was a considerable distinction in the mean level of serum triglyceride and cholesterol between the control group, light smokers and heavy smoker groups (P<00.5). The mean value of HDL of control, light smokers and heavy smokers was 30.93±1.30mg/dl, 31.10±2.45 and 34.58±1.55mg/dl, respectively. The mean values of LDL and VLDL of control, light smokers and heavy smokers were 110.46±3.63mg/dl, 106.00±4.52mg/dl, 117.19±3.48mg/dl and 33.54±3.11mg/dl, 49±9.02mg/dl, 41.06±5.34mg/dl, respectively. There was significant difference in the mean level of HDL, LDL and VLDL between the control group, light smokers and heavy smoker groups (P<0.05). Conclusion: This study concluded that smoking is the reasons of variation in the lipid profile. Elevated period of smoking and the number of smoked cigarettes/day reason the alteration in serum lipid levels and is probably related with increased danger for coronary artery disease.

scholarly journals A Comparative Study of Lipid Profile in Obese and Nonobese Men attending Master Health Checkup

2017 ◽  
Vol 21 (2) ◽  
pp. 73-75
Author(s):  
S Vinod Babu ◽  
Anusha R Jagadeesan ◽  
Jothimalar Ramalingam
Keyword(s):  
Comparative Study ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
P Value ◽  
Health Checkup ◽  
Group I ◽  
Significant Difference

ABSTRACT Introduction Obesity is emerging as an epidemic worldwide. Obesity is associated with a number of comorbid conditions, such as diabetes mellitus, hypertension, cancer, dyslipidemia, cardiovascular abnormalities, anemia, obstructive sleep apnea, and psychosocial abnormalities. Aim This study aims at comparing the lipid profile levels of obese and nonobese men. Materials and methods This was a case—control study conducted at a tertiary care center. Totally, 80 men in the age group of 20 to 47 years attending the master health checkup were included in the study, out of which 40 men with normal body mass index (BMI) of 18 to 25 belonged to group I and 40 men with increased BMI of 30 and above belonged to group II. Lipid profile parameters, such as triglycerides (TGLs), total cholesterol, high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol were estimated in them. The data were statistically analyzed using Statistical Package for the Social Sciences (SPSS) software version 15.0. Results Statistically significant difference was found in the total cholesterol levels with a p-value of 0.040 while the difference in LDL cholesterol was statistically highly significant with a p-value of 0.040. Conclusion Among lipid profile parameters, only total cholesterol and LDL cholesterol showed significant difference between the obese and nonobese individuals. However, the other parameters like HDL cholesterol and TGLs did not show any significant difference. How to cite this article Babu SV, Jagadeesan AR, Ramalingam J. A Comparative Study of Lipid Profile in Obese and Nonobese Men attending Master Health Checkup. Indian J Med Biochem 2017;21(2):73-75.

scholarly journals EARLY PREDICTORS OF RENAL DYSFUNCTION IN Β-THALASSEMIA MAJOR AND INTERMEDIA PATIENTS

2004 ◽  
Vol 6 (1) ◽  
pp. e2014057 ◽  
Author(s):  
Azza A.G. Tantawy ◽  
Nagham El Bablawy ◽  
Amira A. M Adly ◽  
Fatma S E Ebeid
Keyword(s):  
Renal Dysfunction ◽  
Serum Ferritin ◽  
Total Protein ◽  
Plasma Osmolality ◽  
Thalassemia Major ◽  
Total Serum ◽  
Protein Z ◽  
Early Predictors ◽  
Group I ◽  
Significant Difference

Background: Better survival of thalassemia patients allowed previously unrecognized renal complications to emerge. Objectives: Assess prevalence and early predictors of renal dysfunction in young β-thalassemia major (β-TM) and intermedia (β-TI) patients. Subjects: 66 β-TM (group I), 26 β-TI (group II) Egyptian patients and 40 healthy controls. Methods: History, examination and investigations that included kidney function tests, serum ferritin, serum bicarbonate, plasma osmolality and urinary total proteins, microalbuminuria (MAU), N-acetyl-β-D-glucosaminidase (NAG), retinol binding protein (RBP), α-1 microglobulin, bicarbonate, osmolality, Creatinine clearance (CrCl), % fractional excretion of bicarbonate (% FE-HCO3). Results: The most common renal abnormality was proteinuria (71%), followed by increased urinary level of RBP (69.4%), NAG (58.1%), α-1 microglobulin (54.8%) and microalbumin (29%) and also decreased urinary osmolality (58.1%). Although serum creatinine and BUN were not statistically different between thalassemia patients and control, CrCl were significantly lowered in thalassemia patients. Total serum protein and albumin was significant lower in splenectomized β-TM, whereas urinary total protein and MAU were significantly increased in all thalassemia patients. NAG, RBP and α-1 microglobulin were negatively correlated with CrCl and positively correlated with serum ferritin and urinary total protein. Z-score analysis for discrimination of patients with renal dysfunction proved superiority of urine total protein and RBP. Comparative statistics of different frequencies revealed significant difference between the urinary total protein and both MAU and % FE-HCO3. Conclusion: Asymptomatic renal dysfunctions are prevalent in young β-TM and β-TI patients that necessitate regular screening and urinary total protein and RBP may be cost-effective for early detection.

scholarly journals Effect of Helicobacter pylori Infection on Serum Lipid Profile

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Mohamadreza Haeri ◽  
Mahmoud Parham ◽  
Neda Habibi ◽  
Jamshid Vafaeimanesh
Keyword(s):  
Helicobacter Pylori ◽  
Lipid Profile ◽  
Blood Sugar ◽  
Serum Lipid ◽  
Density Lipoprotein ◽  
Population Data ◽  
Serum Lipid Profile ◽  
Significant Difference ◽  
H Pylori ◽  
The Relationship

Background. Some studies suggest a significant relationship between Helicobacter pylori infection and atherogenesis; but the mechanism of the relationship is almost unknown. The current study aimed at evaluating the relationship between H. pylori infection and serum lipid profile. Patients and Methods. The current study was conducted on 2573 patients, from 2008 to 2015. The serum anti-Helicobacter pylori antibody titer and serum lipid profile were assessed in the study population; data were statistically analyzed by SPSS version 16. P values < 0.05 were considered significant. Results. In the current study, 66.5% of the cases were serologically positive for H. pylori. Among male cases, the level of low density lipoprotein (LDL) was higher in patients with H. pylori infection, compared with that of the ones without the infection (P=0.03); although level of triglyceride (TG) was higher and the level of high density lipoprotein (HDL) was lower in the cases with H. pylori infection; there was no statistically significant difference between the cases with and without H. pylori infection regarding the level of HDL and TG. Among female cases, the level of TG was significantly lower in patients with H. pylori infection, compared with that of the ones without the infection (P=0.001); but there was no significant difference between the cases with and without H. pylori infection regarding the level of LDL and HDL. The mean fasting blood sugar (FBS) in the cases with H. pylori infection was significantly higher than that of the ones without the infection (P=0.04). Conclusion. According to the results of the current study, the levels of LDL and FBS were high among the male cases with H. pylori infection. However, in females with H. pylori infection the level of TG was low; hence, it seems that the atherogenicity of H. pylori affected the level of blood sugar more.

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