scholarly journals Differential GFR estimation of the double moiety kidneys by modified GATE’S formula

2021 ◽  
Vol 3 (3) ◽  
pp. 01-07
Author(s):  
Sivasubramaniyan V
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Physical Properties ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
Living Cells ◽  
Advanced Imaging ◽  
Wide Range ◽  
Gfr Estimation ◽  
Or Gene

Since the beginning of the twenty-one century, carbon based nanomaterial (CNTs) has been introduced in (pharmacy and medicine) in therapeutic for system of drug delivery. NTs have proved able to transport a wide range of molecules across membranes and into living cells; therefore, they have attracted great interest in biomedical applications such as advanced imaging, tissue regeneration, and drug or gene deliver. As it is known, carbon nanotubes exhibit various unique intrinsic chemical and physical properties and it has been intensive explored, in the last few years, for applications in biology and biomedicine.

Pharmaceutical Applications of Carbon Nanotube-Mediated Drug Delivery Systems

2012 ◽  
Vol 5 (2) ◽  
pp. 1685-1696 ◽  
Author(s):  
Pradeep Kumar S ◽  
Prathibha D ◽  
Gowri Shankar N L ◽  
Parthibarajan R ◽  
Mastyagiri L ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Cancer Treatment ◽  
Drug Delivery System ◽  
Delivery System ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Width Ratio ◽  
Wide Range

Carbon nanotubes, which are elongated fullerenes, resemble graphite sheets wrapped into cylinders with a high length-to-width ratio (few nm in diameter and up to 1 mm in length). Carbon nanotubes are molecular-scale tubes of graphitic carbon with outstanding properties. Carbon nanotubes have drawn great interest and attraction in the field of novel drug delivery system. Nanomedicines can target, diagnose, monitor and treat cancerous cell also. The small nanoscale dimension and astonishing properties make them a distinctive carrier with a wide range of promising applications. These cylindrical carbon molecules have novel properties that make them potentially useful in many applications in nanotechnology. The various nano-size carrier systems are available for biotechnological applications including the drug delivery. Carbon nanotubes are typically used for bioactive delivery due to their some unique outstanding properties. Carbon nanotubes drug delivery system opens up new potential and possibilities over nanoparticles, dendrimers, liposomes etc. for biomedical applications and new drug delivery. In last few years, Carbon nanotubes (CNTs) have shown unexpected advantages in the field of cancer treatment and drug delivery systems. Present review article discuss in brief about the methods of synthesis, with purification as well as sorting techniques for giving different grades to different types of CNTs and biomedical applications. These show very good adsorption properties which helps in the detection of various chemicals, toxic agents etc. Research done using CNTs for cancer treatment is also discussed in brief.  

Recent advances in the design of inorganic and nano-clay particles for the treatment of brain disorders

2021 ◽  
Author(s):  
Francesca Persano ◽  
Svetlana Batasheva ◽  
Gölnur Fakhrullina ◽  
Giuseppe Gigli ◽  
Stefano Leporatti ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Silica Nanoparticles ◽  
Biomedical Applications ◽  
Inorganic Materials ◽  
Brain Disorders ◽  
Clay Particles ◽  
Recent Advances ◽  
Wide Range ◽  
Nano Clay

Inorganic materials, in particular nanoclays and silica nanoparticles, have attracted enormous attention due to their versatile and tuneable properties, making them ideal candidates for a wide range of biomedical applications, such as drug delivery.

A Review on Application of Novel Solid Nanostructures in Drug Delivery

2018 ◽  
Vol 53 ◽  
pp. 22-36 ◽  
Author(s):  
Habibollah Faraji ◽  
Reza Nedaeinia ◽  
Esmaeil Nourmohammadi ◽  
Bizan Malaekeh-Nikouei ◽  
Hamid Reza Sadeghnia ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Therapy ◽  
Biomedical Applications ◽  
Imaging Biomarkers ◽  
Cellular Functions ◽  
Scientific Innovation ◽  
Wide Range ◽  
Targeted Drug

Nanotechnology as a multidisciplinary and scientific innovation plays an important role in numerous biomedical applications, such as molecular imaging, biomarkers and biosensors and also drug delivery. A wide range of studies have been conducted on using of nanoparticles for early diagnosis and targeted drug therapy of various diseases. In fact, the small size, customized surface, upgraded solubility, or multi-functionality of nanoparticles enabled them to interact with complex cellular functions in new ways which opened many doors and created new biomedical applications. These studies demonstrated that nanotechnology vehicles can formulate biological products effectively, and this nano-formulated products with a potent ability against different diseases, were represented to have better biocompatibility, bioaccessibility and efficacy, under in vitro and in vivo conditions.

Advanced Technologies in DNA-based Nanomedicine

2021 ◽  
Vol 15 ◽  
Author(s):  
Ameneh Mohammadi ◽  
Pooria Gill ◽  
Pedram Ebrahimnejad ◽  
Said Abediankenari ◽  
Zahra Kashi
Keyword(s):  
Drug Delivery ◽  
Gene Therapy ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Dna Nanostructures ◽  
Medical Sciences ◽  
Rational Engineering ◽  
Advanced Technologies ◽  
Wide Range ◽  
Or Gene

: The application of nanotechnology in medicine and pharmaceutical purpose suggested a novel procedure in the nanotechnology terminology as nanomedicine. There is a wide range of applications for nanotechnology in medicine, such as the use of nanocarriers in drug delivery systems. Recently a remarkable attention to DNA has been made through its amazing functionality and its nature as a nanomaterial in biological systems. Since DNA is a biocompatible, the use of DNA as a nanomaterial in medicine has shown a great perspective of rational engineering of DNA nanostructures. According to new approaches in treatment of diseases in gene levels, gene therapy, using DNA as a nanomedicine possesses an important role in the medical sciences as the researchers published enormous papers and patents in the fields, for instance, the applications of DNA and DNA-based nanostructures as drug or gene nanocarriers, DNA-based diagnostics and DNA nanovasccines. Here, some examples of DNA-based nanomedicine in the patent frame were reviewed.

Biomedical Applications of Nanoparticles

2022 ◽  
pp. 289-311
Author(s):  
Raghavv Raghavender Suresh ◽  
Shruthee Sankarlinkam ◽  
Sai Rakshana Karuppusami ◽  
Niraimathi Pandiyan ◽  
Suwetha Bharathirengan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Biomedical Applications ◽  
Medical Diagnostics ◽  
Engineered Nanoparticles ◽  
Biological Molecules ◽  
Toxicological Evaluation ◽  
Nanodrug Delivery ◽  
Novel Drugs ◽  
Wide Range ◽  
Targeted Drug

In recent years, there has been significant growth and burgeoning interest in utilizing nanoparticles for various biomedical applications, including medical diagnostics, targeted drug delivery, tissue engineering, regenerative medicine, and biomedical textiles. In particular, nanoparticles functionalized with biological molecules have unique properties and are very effective in medical diagnostics. Besides that, nanoparticles have a wide range of therapeutic applications, including the development of nanodrug delivery systems, the design of novel drugs, as well as their contribution to the design of therapeutic materials. This chapter provides an overview of recent advancements in the biomedical applications of nanoparticles. Finally, this chapter discusses the challenges of the toxicological evaluation of engineered nanoparticles and the importance of conducting detailed studies on the synthesis of future nanomaterials to develop cutting-edge technologies for addressing a wide range of biomedical issues.

scholarly journals Marine Polysaccharides in Pharmaceutical Applications: Fucoidan and Chitosan as Key Players in the Drug Delivery Match Field

Marine Drugs ◽  
2019 ◽  
Vol 17 (12) ◽  
pp. 654 ◽  
Author(s):  
Ana Isabel Barbosa ◽  
Ana Joyce Coutinho ◽  
Sofia A. Costa Lima ◽  
Salette Reis
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Biomedical Applications ◽  
Chemical Structure ◽  
Final Section ◽  
Biological Properties ◽  
Production Methods ◽  
Bioactive Properties ◽  
Wide Range ◽  
Per Se

The use of marine-origin polysaccharides has increased in recent research because they are abundant, cheap, biocompatible, and biodegradable. These features motivate their application in nanotechnology as drug delivery systems; in tissue engineering, cancer therapy, or wound dressing; in biosensors; and even water treatment. Given the physicochemical and bioactive properties of fucoidan and chitosan, a wide range of nanostructures has been developed with these polysaccharides per se and in combination. This review provides an outline of these marine polysaccharides, including their sources, chemical structure, biological properties, and nanomedicine applications; their combination as nanoparticles with descriptions of the most commonly used production methods; and their physicochemical and biological properties applied to the design of nanoparticles to deliver several classes of compounds. A final section gives a brief overview of some biomedical applications of fucoidan and chitosan for tissue engineering and wound healing.

scholarly journals Titanium-containing bioactive phosphate glasses

2012 ◽  
Vol 370 (1963) ◽  
pp. 1352-1375 ◽  
Author(s):  
A. Kiani ◽  
N. J. Lakhkar ◽  
V. Salih ◽  
M. E. Smith ◽  
J. V. Hanna ◽  
...  
Keyword(s):  
Physical Properties ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
Review Paper ◽  
Phosphate Glasses ◽  
Bone Substitute Material ◽  
Soft Tissue Regeneration ◽  
Recent Developments ◽  
Titanium Incorporation ◽  
Biomedical Field

The use of biomaterials has revolutionized the biomedical field and has received substantial attention in the last two decades. Among the various types of biomaterials, phosphate glasses have generated great interest on account of their remarkable bioactivity and favourable physical properties for various biomedical applications relating to both hard and soft tissue regeneration. This review paper focuses mainly on the development of titanium-containing phosphate-based glasses and presents an overview of the structural and physical properties. The effect of titanium incorporation on the glassy network is to introduce favourable properties. The biocompatibility of these glasses is described along with recent developments in processing methodologies, and the potential of Ti-containing phosphate-based glasses as a bone substitute material is explored.

Functional Nanodiamond Internalization Mechanisms and Kinetics

2010 ◽  
Author(s):  
Robert Lam ◽  
Xueqing Zhang ◽  
Mark Chen ◽  
Dean Ho
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Surface Modification ◽  
Aspect Ratio ◽  
Biomedical Applications ◽  
Internalization Mechanism ◽  
Mechanism And Kinetics ◽  
Energy Dependent ◽  
The Relationship ◽  
Kinetics Of

Several reports have described the relationship between size, aspect ratio, surface modification and internalization for a variety of nanoparticles (i.e. gold, polymer, carbon nanotubes). Nanodiamonds (NDs) in particular have recently been implicated in a variety of biomedical applications. One of the most promising is in utilizing NDs as drug delivery carriers where successful internalization is of utmost importance. A few reports recently have demonstrated the energy dependent internalization of bare NDs. In this report, we investigate the internalization mechanism and kinetics of functional ND-conjugate translocation.

scholarly journals Electrospinning of Nanofibers for Tissue Engineering Applications

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Haifeng Liu ◽  
Xili Ding ◽  
Gang Zhou ◽  
Ping Li ◽  
Xing Wei ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
Fiber Morphology ◽  
Hard Tissue ◽  
Nanoscale Material ◽  
Considerable Potential ◽  
Recent Interest ◽  
Material Fabrication

Electrospinning is a method in which materials in solution are formed into nano- and micro-sized continuous fibers. Recent interest in this technique stems from both the topical nature of nanoscale material fabrication and the considerable potential for use of these nanoscale fibres in a range of applications including, amongst others, a range of biomedical applications processes such as drug delivery and the use of scaffolds to provide a framework for tissue regeneration in both soft and hard tissue applications systems. The objectives of this review are to describe the theory behind the technique, examine the effect of changing the process parameters on fiber morphology, and discuss the application and impact of electrospinning on the fields of vascular, neural, bone, cartilage, and tendon/ligament tissue engineering.

scholarly journals Growth, Properties, and Applications of Branched Carbon Nanostructures

Nanomaterials ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 2728
Author(s):  
Sharali Malik ◽  
Silvia Marchesan
Keyword(s):  
Carbon Nanotubes ◽  
Tissue Regeneration ◽  
Carbon Nanostructures ◽  
Structural Features ◽  
Theoretical Studies ◽  
Concise Review ◽  
Wide Range ◽  
Growth Properties ◽  
Experimental And Theoretical Studies ◽  
Advanced Applications

Nanomaterials featuring branched carbon nanotubes (b-CNTs), nanofibers (b-CNFs), or other types of carbon nanostructures (CNSs) are of great interest due to their outstanding mechanical and electronic properties. They are promising components of nanodevices for a wide variety of advanced applications spanning from batteries and fuel cells to conductive-tissue regeneration in medicine. In this concise review, we describe the methods to produce branched CNSs, with particular emphasis on the most widely used b-CNTs, the experimental and theoretical studies on their properties, and the wide range of demonstrated and proposed applications, highlighting the branching structural features that ultimately allow for enhanced performance relative to traditional, unbranched CNSs.

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