scholarly journals SOME CHARACTERISTICS OF THE COURSE OF CORONARY HEART DISEASE WITH A COMORBID PATHOLOGY

2020 ◽  
Vol 24 (1-2) ◽  
pp. 8-11
Author(s):  
Т.А. Trybrat ◽  
S.V. Shut ◽  
Z.O. Borisova ◽  
V.D. Sakevych ◽  
O.O. Goncharova
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Clinical Medicine ◽  
Nyha Class ◽  
Severe Disease ◽  
Age Group ◽  
Comorbid Conditions ◽  
Group Iii ◽  
Group I ◽  
Number Of Patients

Nowadays, scientists and doctors are increasingly paying attention to the study of the cardinal problem of modern clinical medicine, comorbidity and polymorbidity, which may arise as a result of common etiology, pathogenesis, cause and effect influences (the syntopic impairments) or as an accidental combination of disease (the accompanying impairments) with age factor, anatomical closeness of the affected organs or accidental combination of diseases. The aim: to define the concomitant diseases and their course, which are most often observed in patients with CHD. The prospective study involved 100 patients with coronary heart disease: stable angina, І-ІV NYHA Class, І-II HF. Results and discussion. The incidence of combined pathology in patients with CHD increases with age: in group I, one of the comorbid conditions prevails (mainly gastrointestinal tract diseases), in group II and III, there are two or more concomitant diseases. Among the total number of patients, 95% live in the city, hence the result of the urbanization process, and only 5% live in the village. The analysis of medicines prescriptions, used in the treatment of patients with CHD revealed an increased use of larger amounts of drugs in age group III (≥60) as compared to groups I (≤40) and II (41-60). Adequate combined prescriptions of medicines to patients with comorbid conditions will allow us not only to prevent progression of each disease, but also to improve the long-term prognosis. Essential hypertension is the «leader» in the total number of comorbid diseases, which makes up 77% of patients among the total number of subjects, with the highest incidence in the II (41-60) and III (≥60) age group. Thus, the obtained results indicate differences in the course and clinical presentation of coronary heart disease, depending on the presence of comorbid pathology, which leads to a more severe disease course, a greater number of comorbidities with increasing age of patients.

scholarly journals Epidemiological aspects of nephrolithiasis and chronic diseases of the cardiovascular system combination

2020 ◽  
Vol 7 (1) ◽  
pp. 38-47
Author(s):  
R. V. Royuk ◽  
S. K. Yarovoy ◽  
N. A. Guseva ◽  
Sh. L. Voskanyan ◽  
V. V. Royuk ◽  
...  
Keyword(s):  
Heart Failure ◽  
Coronary Heart Disease ◽  
Congestive Heart Failure ◽  
Heart Disease ◽  
Cardiovascular Diseases ◽  
Arterial Hypertension ◽  
Kidney Stones ◽  
Group Iii ◽  
Group I ◽  
First Time

Purpose of the study. To analyze prevalence and characteristics of the cardiovascular diseases (CVD) in patients with urolithiasis, revealed for the first timeMaterials and methods. In a period between 2009 and 2018, was made a retrospective analysis of medical histories of 2311 patients with urolithiasis, which were treated in in the urology departments of the branch No. 1 of the MCHG named after N.N. Burdenko (n=1487) and GBUZ MO Krasnogorsk City Hospital No. 1 (n=824). In 67,6% of the cases (1562 patients) the diagnosis of urolithiasis was diagnosed for the first time on admission. Isolated urolithiasis was recorded in 676 cases (43,3%), in other 154 cases (9,8%) nephrolithiasis was combined with different variants of cardiovascular diseases (CVD) and diabetes. From 732 respondents with urolithiasis and associated cardiovascular diseases (CVD), were formed 3 groups, in the first group (I) were included patients (n=363) with hypertension and arterial hypertension: the second group (II; n=79) was formed from patients with isolated coronary heart disease. In the third group (III) were included 290 patients which had urolithiasis combined with hypertension, arterial hypertension and coronary heart disease. The stages of hypertension and degree of expression of arterial hypertension were given according to the recommendations of Russian science society of cardiology (2004). Stages of congestive heart failure were defined according to c NYHA (New York Heart Association) classification. Functional class of stable angina was defined according to Canadian Cardiovascular Society classification (1970,1976). The obtained data was analyzed using descriptive statistics methods.Results. Average age of patients was 65,4 +– 3,27; 78% of the patients were men. On an emergency basis were hospitalized 30,9% from group I, 27,6% from group 2, and 31,3% from group III. In group I more often were recorded hypertension I + arterial hypertension I (32,5%) and hypertension II + arterial hypertension II (40,2%). In group II effort angina was recorded in 30 cases (38%). Congestive heart failure occurred among 153 patients (20,9%); most often it occurred among patients from III – in 102 cases (35,2%). In the whole sample, congestive heart failure of I and II degrees prevailed – in 88 (12%) and 57 (7,9%) patients. Kidney stones were found in 59,4% of patients, in the ureters – in 30,9% of patients, in kidneys and in the ureters – in 9,9% of patients. Share of the patients with kidney stones in the shape of corals is 3,4% of the whole sample. Average sizes of kidney stones of the patients with congestive heart failure are 9,2–11,8 mm which is different from the sizes in whole sample – 6,9–9,5 mm.Conclusion. During the observation period, share of the patients with first time revealed urolithiasis, complicated with the cardiovascular diseases (CVD) increased in 1,9 times (16,7 versus 31,7%). Congestive heart failure, which was registered in 20,9% of patients, was charged with I and II degrees. The presence chronic cardiovascular diseases (CVD), especially complicated by congestive heart failure in patients with first time revealed nephrolithiasis, implies changes in the algorithms of metaphylactic of nephrolithiasis (regime of water loads, selection of diuretics and anticoagulants).

Video laparoscopic diagnostics and surgical tactics for acute diseases of abdominal organs

2021 ◽  
pp. 17-24
Author(s):  
A. S. Ermolov ◽  
V. T. Samsonov ◽  
P. A. Yartsev ◽  
A. A. Gulyaev
Keyword(s):  
Clinical Diagnosis ◽  
Definitive Diagnosis ◽  
Concomitant Disease ◽  
Group Iii ◽  
Abdominal Organs ◽  
Group I ◽  
Number Of Patients ◽  
Video Laparoscopy ◽  
Surgical Tactics ◽  
Diagnosis Of Diseases

The article presents the results of video laparoscopy (VLS) performed in 2008–2019 in 5,599 patients in order to diagnose acute diseases of the abdominal organs requiring emergency surgery, identify competing and concomitant diseases, and determine treatment tactics. 2,442 (43.6 %) of them made up group I, with no doubt; 2,656 (47.4 %) – II group, with presumptive reliability; and 501 (9.0 %) – group III, with an unclear clinical diagnosis of the disease. In 2,326 (95.2 %) patients of group I with VLS, the clinical diagnosis was confirmed, in 100 (4.1 %) other diseases were revealed, and in 16 (0.7 %) the diagnosis was not established. Competing diseases were found in 8 patients and concomitant diseases in 4. In 1,641 (61.8 %) patients of group II, VLS made it possible to clarify and differentiate the clinical diagnosis of diseases, in 929 (35.0 %) – to identify other diseases, and in 86 (3.2 %) the diagnosis was not possible. When performing differential diagnosis, 126 other diseases were identified more than the number of patients. Competing diseases were found in 6 patients and concomitant diseases in 6 patients. 356 (71.0 %) patients of group III with VLS were diagnosed with major diseases, 75 (15.0 %) had other diseases, and 70 (14.0 %) were not diagnosed. In 4 patients, competing diseases were found, and in 1 – concomitant disease. Of the 5,427 (96.9 %) patients with the definitive diagnosis of the disease established with VLS, 3,828 (70.5 %) were found to be able to perform VLS operations, in 10 (0.3 %) of them – simultaneous with competing diseases.

scholarly journals Assessment of intraocular pressure in chinchillas of different age groups using rebound tonometry

2016 ◽  
Vol 46 (8) ◽  
pp. 1466-1471 ◽  
Author(s):  
Flor Diana Yokoay Claros Chacaltana ◽  
João Antonio Tadeu Pigatto ◽  
Ione Terezinha Denardin
Keyword(s):  
Intraocular Pressure ◽  
Age Groups ◽  
Time Of Day ◽  
Age Group ◽  
Group Iii ◽  
Rebound Tonometer ◽  
Indirect Ophthalmoscopy ◽  
Group I ◽  
Schirmer Tear Test ◽  
The Mean

ABSTRACT: The aim of this research was to measure the intraocular pressure (IOP) of normal chinchilla eyes using the rebound tonometer. A further aim was to assess whether there were differences in the values of intraocular pressure in relation to animals age, gender and time of day. Thirty-six chinchillas were divided into three groups of 12 chinchillas each, by age: Group I (2-6-month-old), Group II (20 and 34 months) and Group III (37 and 135 months). Ophthalmic examination was performed previously by Schirmer tear test, slit lamp biomicroscopy, indirect ophthalmoscopy and fluorescein test in all chinchillas. Three measurements of intraocular pressure were assessed on the same day (7, 12 and 19h). Tonometry was performed on both eyes using the rebound tonometer after calibration in "p" mode. Statistical analysis was performed with SigmaPlot for Windows. The mean IOP for groups I, II and III were 2.47±0.581mmHg, 2.47±0.581mmHg and 2.51±0.531mmHg, respectively. No significant differences were reported between age and IOP and no significant differences were reported between the time of day and IOP. The IOP in chinchillas did not differ significantly between genders or ages of the animals, and did not change with time of day.

scholarly journals A STUDY ON PATTERN OF PRESCRIBING MEDICATIONS USED IN SECONDARY PREVENTION OF STROKE

2016 ◽  
Vol 9 (9) ◽  
pp. 328
Author(s):  
Lakshmi R ◽  
Jithin Kc ◽  
Arya G ◽  
Lekshmi P Nair
Keyword(s):  
Diabetes Mellitus ◽  
Secondary Prevention ◽  
Tertiary Care ◽  
Age Group ◽  
Data Collection Form ◽  
Comorbid Conditions ◽  
Exclusion Criteria ◽  
Prescribing Pattern ◽  
Number Of Patients ◽  
Collection Form

ABSTRACTObjectives: The main objectives of this study were to estimate the demographic details of patients with the first incidence of stroke and to study thevarious risk factors for ischemic stroke.Methods: It was a retrospective, observational study carried out for 1 year at the Department of Stroke Medicine of a tertiary care teaching hospitalin Kerala, India. A total of 636 patients were admitted under stroke medicine during the period from July 1, 2014, to July 1, 2015, and who satisfiedthe inclusion and exclusion criteria were included in the study. A standardized data collection form was prepared and necessary data were collectedfrom patient’s medical records.Results: The maximum number of patients was in the age group of 60-69 years. 65.1% patients were residing in the rural area. 60.7% patients weremale. Most of them had hypertension as common comorbidity (21.35%) and the highest number of patients had diabetes mellitus and hypertension(21.7%). Majority of the patients were prescribed with antiplatelets (94.91%), followed by statins (93.8%).Conclusion: A strict control on the comorbid conditions and sticking on to the medications can prevent the occurrence of future stroke.Keywords: Stroke, Secondary prevention, Drugs, Prescribing pattern.

scholarly journals The prognostic role of inflammatory markers in COVID 19 patients – A retrospective analysis.

2021 ◽  
Author(s):  
Shivkumar Gopalakrishnan ◽  
sangeetha kandasamy ◽  
S.Malini ◽  
S.Peer Mohamed ◽  
k.velmurugan
Keyword(s):  
Inflammatory Markers ◽  
Severe Disease ◽  
Radiation Hazard ◽  
P Value ◽  
Binary Logistic Regression Analysis ◽  
Group Iii ◽  
Group I ◽  
Group Ii ◽  
D Dimer

Abstract Background. Approximately 5% of COVID-19 patients suffer near fatal disease. Clinical and radiologic features may predict severe disease albeit with limited specificity and radiation hazard. Laboratory biomarkers are eyed as simple, specific and point of care triage tools to optimize management decisions.This study aimed to study the role of inflammatory markers in prognosticating COVID-19 patients.Methodology. A hospital based retrospective study was conducted on COVID-19 adult inpatients classified into three groups as mild disease-recovered [Group I], severe disease-recovered [Group II] and dead [Group III]. Categorical outcomes were compared using Chi square test. Univariate binary logistic regression analysis was performed to test the association between the explanatory and outcome variables. Unadjusted OR along with 95% CI was calculated. The utility of lab parameters (Ferritin, LDH, D dimer, N/L ratio and PLT/L ratio) in predicting severity of COVID-19 was assessed by Receiver Operative Curve (ROC) analysis. P value < 0.05 was considered statistically significant.Results. The mean age was 49.32 +/- 17.1 years. Among study population, 378 were Group I, 66 Group II, and 56 Group III. Median levels of Ferritin among the 3 groups were 62ng/mL, 388.50 ng/mL and 1199.50 ng/mL. Median value of LDH were 95U/L, 720 and 982.50(p <0.001). D-dimer values of 3 groups were 23.20ng/mL, 104.30 ng/mL and 197.10 ng/mL (p <0.001). CRP done qualitatively was positive in 2 (0.53%), 30 (45.45%) and 53 (94.64%) of patients. The odds of patients suffering severe COVID-19 rose with rising values of ferritin, LDH and D-dimer [unadjusted OR 1.007, 1.004 &1.020]Conclusion. One time measurement of serum ferritin, LDH, D-dimer and CRP is promising to predict outcomes for COVID 19 inpatients. Single qualitative CRP was equally good but more cost effective than quantitative CRP. The most specific combination was NLR, Lymphocyte percentage and D-dimer levels done between 7th – 10th day of symptoms.

scholarly journals A comparative study to ascertain the efficacy of intravenous dexmedetomidine versus intravenous tramadol to prevent post-operative shivering after laparoscopic surgery

2019 ◽  
Vol 6 (3) ◽  
pp. 713
Author(s):  
Kishore K. ◽  
Syed Ali Aasim ◽  
Manish Kumar J.
Keyword(s):  
Laparoscopic Surgery ◽  
Side Effects ◽  
Comparative Study ◽  
General Anaesthesia ◽  
Power Number ◽  
Group Iii ◽  
Group I ◽  
Number Of Patients ◽  
Envelope Method ◽  
Level Of Significance

Background: Shivering is commonly encountered both after regional and general anaesthesia (GA) with a little higher incidence in patients receiving GA. The aim of study was to compare the effectiveness of dexmedetomidine and tramadol in decreasing postoperative shivering in patients undergoing laparoscopic surgery.Methods: Total 120 patients were included in this study. In order to get a 5% level of significance and 80% power number of patients required in each group was 40, with a total of 120 patients. Randomization of groups was done based on closed envelope method. Patients were allocated into three groups group I, II and III of 40 patients each. Patients in group I and group II were administered 0.75 μg/kg of dexmedetomidine and 1.5 mg /kg of tramadol in 100 ml NS respectively half a before extubation, while patients in group III did not receive any pharmacological intervention.Results: All three groups were comparable regarding distribution of age, gender, ASA grade and temperature at beginning and end of surgery and were non-significant.Conclusions: Dexmedetomidine seems to possess anti-shivering properties and was found to reduce the occurrence of shivering in patients undergoing general anaesthesia with minimal side effects although its anti-shivering effect was not superior to tramadol.

scholarly journals Analysis of zinc concentration in the saliva of individuals at different age ranges

2016 ◽  
Vol 31 (1) ◽  
pp. 12
Author(s):  
Marcela Lima Cardoso Selow ◽  
Flávia Lunelli ◽  
Iran Vieira ◽  
Mariana Doff Sotta ◽  
Wilson Denis Martins ◽  
...  
Keyword(s):  
Zinc Concentration ◽  
Zinc Supplementation ◽  
Salivary Flow ◽  
Group Iv ◽  
Oral Lesions ◽  
Age Group ◽  
Healthy Individuals ◽  
Group Iii ◽  
Age Related ◽  
Group I

Objectives: Zinc plays an important role in the homeostasis of the human body. In the oral cavity, its absence causes hypogeusia. Zinc supplementation acts improving taste acuity and oral lesions healing. However, some aspects regarding to salivary zinc contents and syalometric variables, as well as, its variations among age-related groups, are lacking. The objective of this study was to measure the zinc concentration in the saliva in different age range.Methods: One hundred and twenty healthy individuals have donated saliva and they were divided in to four groups according to age: Group I = 18-29 years old; Group II = 30-39 years old; Group III: 40-49 years old and Group IV: 50-59 years old.Results: The research revealed that there are differences between salivary parameters, salivary flow rate, buffering capacity and pH, when they are correlated with the zinc present in saliva, but the salivary zinc concentration is not age dependent.Conclusion: pH and BA had no influence in the salivary zinc concentration, but the salivary flow can interfere in the zinc concentration.

Maturation and Fecundity of Brook Trout from Infertile Streams

1966 ◽  
Vol 23 (5) ◽  
pp. 623-649 ◽  
Author(s):  
Richard S. Wydoski ◽  
Edwin L. Cooper
Keyword(s):  
Brook Trout ◽  
Age Groups ◽  
Reproductive Rate ◽  
Seasonal Development ◽  
Age Group ◽  
Group Iii ◽  
Total Length ◽  
Group I ◽  
Reproductive Rates ◽  
Curvilinear Regression

The reproductive rate of brook trout populations from infertile Pennsylvania streams was determined. The standing crops for eight streams varied between 14 and 41 lb/acre. Trout in age-groups 0 through III were found to grow slowly with very few individuals reaching a total length of 6 inches.The seasonal development of ova was determined by measuring all ova larger than 0.2 mm from selected females. The maturing ova of most females of age-groups II and III increased in diameter from 0.9 mm in February to 1.0 mm in June, 1.75 mm in July, 2.5 mm in August, 3.0 mm in September, and 4.0 mm in October. Maturing females could be distinguished from immature females by late August or early September on the basis of ova diameters. The mean diameter of ripe ova from 67 females was 4.05 mm with a range between 3.37 and 5.01 mm for individual trout ranging from 4.6 to 8.6 inches total length.The relationship between the number of mature ova and the total length of the female for one population was described by a curvilinear regression (log Y = −0.5361 + 3.23 log X, where Y = number of eggs, and X = the total length of the fish) for brook trout between 3.6 inches (18 eggs) and 7.7 inches (213 eggs). Variation in this relationship existed among streams.Ova production was estimated as 9050 ova per acre for one population and 13,620 ova per acre for another. Age-group-I females contributed approximately 9% of this production; age-group-II females, 54%; and age-group-III females, 37%. An ecological life table was constructed for two populations comparing rates of survival, age-specific fecundity rates, and reproductive rates.

scholarly journals Results of holter monitoring in patients with coronary heart disease depending on the severity of atherosclerotic lesions of the coronary arteries

2021 ◽  
pp. 15-19
Author(s):  
Tetiana Pylova
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Comparative Analysis ◽  
Myocardial Ischemia ◽  
Coronary Arteries ◽  
Holter Monitoring ◽  
Group I ◽  
St Segment ◽  
Stable Coronary Heart Disease ◽  
Group Ii

The aim – to conduct a comparative analysis of the presence, frequency and duration of episodes of myocardial ischemia and arrhythmias based on the results of Holter monitoring in patients with coronary heart disease depending on the condition of the coronary arteries. Materials and methods. We examined 53 patients (group I) with stable coronary heart disease (CHD) and slightly altered coronary arteries (INOCA), who were hospitalized in the period from October 2018 to February 2021 at the “City Clinical Hospital № 8” of Kharkiv City Council. Group II included 52 patients with a diagnosis of stable coronary heart disease, and according to coronary angiography (CAG) had stenosis of coronary arteries (CA) more than 50 %. Results. According to the results of comparative analysis, it was found that in group I there were signs of myocardial ischemia – depression of the ST segment in 62.3 % (n=33) and elevation of the ST segment in 11.3 % (n=6), compared with group II -73 % (n=38) and 5.66 % (n=3), respectively. Ventricular arrhythmias (VA) have been reported in 52 patients of group I, and in 44 patients of group II. VA 4 and 5 type according to Laun, was significantly higher in group II compared with group I (p=0.0324). The occurrence of ventricular tachycardia was recorded in 5.7 % (n=3) of patients in group I and 9.3 % (n=5) patients of group II (p=0.347). In group II, there was a tendency to more episodes of ischemia compared with group I (p=0.072). The duration of ischemia was significantly longer in group I, compared with group II (p=0.042). Conclusions. The results of the study did not show significant differences in the development of the number of episodes of myocardial ischemia according to Holter monitoring depending on the condition of the coronary arteries. The duration of episodes of ischemia in patients with INOCA is significantly longer than in patients with obstructive atherosclerosis. In patients with coronary heart disease with obstructive coronary arteries, ventricular arrhythmia was statistically significantly more severe according to Lown

scholarly journals Prevalence Proportion of Patient with Coronary Heart Disease in Inpatient Room of RSUD Dr. Soetomo Surabaya in 2017

2020 ◽  
Vol 3 (2) ◽  
pp. 95
Author(s):  
Faradila Budi Saputri ◽  
Dyah Fauziah ◽  
Esti Hindariati
Keyword(s):  
Coronary Heart Disease ◽  
Risk Factor ◽  
Heart Disease ◽  
Diastolic Pressure ◽  
Systolic Pressure ◽  
Common Type ◽  
Age Group ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Prevalence Proportion

Introduction: Coronary heart disease (CHD) is the most common type of heart disease that causes death. It occurs as a result of hardening of the coronary arteries which supply oxigen-rich blood to the entire heart muscle so that the heart can contract properly. However, many patients neglect the symptoms. Moreover, the risk factor and the comorbides disease worsen the condition. This research aims to study the profile of coronary heart disease patients in the inpatient rooms at Dr. Soetomo General Hospital Surabaya in 2017.Methods: This study was a cross-sectional and retrospective study by assessing patients’ medical record and analyzed descriptively.Results: From total 587, 263 patiens met inclusion criteria, aged between 51-60 years (42.6%) with domination of male (82,13%). %). Risk Factors are into one of the Comorbidities of CHD Patient. There are Risk Factor can be aggravate of CHD Patients. Most of subjects had risk factor hipertension (50,79%), and hypertension with DM (38,7%). Hypertension based on systolic pressure and diastolic pressure obtained that systolic pressure <120 mmhg was 39.6% and diastolic pressure <80 was 37.4%.Conclusion: Most of CHD patients in this study were in age group 51 – 60 years old, male, had risk factor hypertension and DM.

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