scholarly journals IDENTIFICATION OF RISK FACTORS AMONG MYOCARDIAL INFARCTION PATIENTS ATTENDING DARBHANGA MEDICAL COLLEGE AND HOSPITAL.

Author(s):  
Dr. Kumari Suruchi ◽  
Dr. Kumar Durgeshwar ◽  
Dr. Pradeep Kumar Sharma ◽  
Dr.P. K. Sinha

INTRODUCTION: Coronary heart diseases (CHD) is the most common serious disease in developed countries and an acute developing health problem in developing countries and have imposed numerous social and economic costs in developed countries. It is known that MI is caused by smoking, which also causes endothelial dysfunction. There are about 80% cases of MI in developing countries but the studies on risk factors are mostly done in countries which are developed.  It seems to be important to emphasize on studies on risk factors of MI. The mortality of these diseases are shown to increase in developing countries due to lack of familiarity with risk factors associated to coronary heart diseases and failure to comply with preventive measures.  MATERIAL AND METHODS: In this prospective case-control study information was collected on demographic characteristics, history of cardiovascular disease, lifestyle (smoking) and risk factors using structured questionnaire. Critically ill patients with HIV/AIDS or other major diseases like liver failure, kidney failure, etc. were excluded from the study. RESULTS: In present study 118 cases and same number of matched controls were included. It was found that in this study, 97(82.2%) cases had smoking habits whereas 61(51.7%) of controls were smokers. Statistically significant smokers were observed in cases. Among all MI patients, 76(64.4%) had family history of CAD while it was present in 32.2% non-MI patient, difference was statistically significant. A significant proportion of cases (72.3%) had high serum lipid levels compared to controls (43.2%). Among all cases 94(79.7%) were hypertensive and 82(69.5%) controls suffered from hypertension, but the difference was not statistically significant. Prevalence of diabetes among cases 72(61.0%) and controls 68(57.6%) was not statistically significant, although prevalence was high in cases. 5(4.2%) of cases had Coronary artery bypass graf(CABG). CONCLUSION: Most common predictors of MI in our study were smoking, high serum lipid levels, family history of CAD, hypertension and diabetes. Early identification and modification of the risk factors is important for preventing MI.

2021 ◽  
Vol 34 (1) ◽  
pp. 26-32
Author(s):  
Md Amzad Hossain Sardar ◽  
Md Khalilur Rahman ◽  
Md Mahidul Alam ◽  
Md Aminul Hasan ◽  
Ashoke Sarker ◽  
...  

Background: Among non-communicable diseases, acute myocardial infarction (AMI) is a common killer of people in the world. The management of AMI patients is one of the major challenges in the field of cardiology. Uric acid has several effects of potential interest in cardiovascular disease. There are some markers indicating an unfavorable prognosis in AMI patients. Uric acid is one of the markers that have been evaluated in research. Objective: The aim of this study was to assess the association between serum uric acid level and in-hospital outcomes of AMI patients. Patients and methods: This longitudinal descriptive study was conducted over 115 AMI patients in the Cardiology Unit of Rajshahi Medical College Hospital during the period of January 2015 to December 2016. Baseline characteristics such as age, sex, BMI, BP, RBS, risk factors (hypertension, DM, smoking, family history of IHD, dyslipidemia), and outcomes of AMI patients (acute LVF, arrhythmia, conduction block, cardiogenic shock, death) were recorded. We measured the serum uric acid of this patient at admission.  Results: The mean age of patients was 52.83±10.71 years. Out of 115 patients, 83.5% were male, and 16.5% were female. Among the risk factors, 65.2% of patients had HTN, 20.9% DM, 64.3% smoking, 16.5% family history of IHD, and 47.8% dyslipidemia. Out of 115, 35.7% of patients demonstrated high serum uric acid. In outcomes of AMI patients, acute LVF 24.4% (p=0.031) and death 12.2% (p=0.041) were significantly higher in patients with high serum uric acid levels. Conclusion: Significant association was found between high serum uric acid level and in-hospital outcomes of AMI patients. So, estimation of serum uric acid may offer an inexpensive, quick, and non-invasive method for identifying such high-risk patients. TAJ 2021; 34: No-1: 26-32


2021 ◽  
Vol 15 (6) ◽  
pp. 267-276 ◽  
Author(s):  
Chayamon Suwansumrit ◽  
Worawan Jittham

Abstract Background Congenital heart diseases (CHDs) are the most common types of birth defects and contribute to a large proportion of infant morbidities and mortalities worldwide. These defects may require multiple surgical interventions impacting the infant's quality of life. Objectives To identify risk factors associated with CHD in a population of Thai children. Methods We conducted a case–control study of patients attending the Pediatric Clinic, Naresuan University Hospital, Thailand. We included data from pediatric patients diagnosed with CHDs as cases, and patients without cardiovascular abnormalities as controls. Risk data were collected from July 2019 to April 2020 using face-to-face interviews. Multiple logistic regression was used to analyze parental factors associated with CHDs. Results We included 249 cases classified into 2 groups according to severity and 304 patients as controls. For those less-severely affected (155 patients, 62.2%), ventricular septal defect (27.7%) was the most prevalent, whereas for those with severe CHDs, tetralogy of Fallot was the most prevalent (14.0%). There was no difference in sex distribution or maternal obstetric history between the groups. In multivariable analysis, a family history of CHDs (adjusted odds ratio [AOR] 4.67, 95% confidence interval (CI) 1.61–13.57, P = 0.005) and maternal exposure to second-hand cigarette smoke (AOR 1.58, 95% CI 1.03–2.42, P = 0.002) were identified as significant risk factors for CHDs. Conclusion A family history of CHDs and maternal exposure to second-hand cigarette smoke are associated with having offspring with CHDs in the population studied. These findings help us to encourage affected parents to obtain a fetal echocardiogram.


Crisis ◽  
2005 ◽  
Vol 26 (3) ◽  
pp. 112-119 ◽  
Author(s):  
Lakshmi Vijayakumar ◽  
Sujit John ◽  
Jane Pirkis ◽  
Harvey Whiteford

Abstract. The majority of studies on risk factors for suicide have been conducted in developed countries, and less work has been done to systematically profile risk factors in developing countries. The current paper presents a selective review of sociodemographic, clinical, and environmental/situational risk factors in developing countries. Taken together, the evidence suggests that the profiles of risk factors in developing countries demonstrate some differences from those in developed countries. In some developing countries, at least, being female, living in a rural area, and holding religious beliefs that sanction suicide may be of more relevance to suicide risk than these factors are in developed countries. Conversely, being single or having a history of mental illness may be of less relevance. Risk factors that appear to be universal include youth or old age, low socioeconomic standing, substance use, and previous suicide attempts. Recent stressful life events play a role in both developing and developed countries, although their nature may differ (e.g., social change may have more of an influence in the former). Likewise, access to means heightens risk in both, but the specific means may vary (e.g., access to pesticides is of more relevance in developing countries). These findings have clear implications for suicide prevention, suggesting that preventive efforts that have shown promise in developed countries may need to be tailored differently to address the risk factor profile of developing countries.


2015 ◽  
Vol 22 (10) ◽  
pp. 1316-1320
Author(s):  
Sayed Fasih Ahmed Hashmi ◽  
Ambreen Haidar

OBJECTIVE: The target of this study to focus, vitamin D level is the significant riskfactors for the patients with cardio vascular disease at Liaquat University Hospial Hyderabad /Jamshoro. Materialand Methods: This observational study was done at cardiology departmentof Liaquat University Hospital Hyderabad. All the cases with history of congenital heart disease,pregnancy, malignancy, renal failure and chronic liver disease, were excluded from the study.Complete medical history was taken, and major risk factors of the cardiovascular diseaseincluding, diabetes, smoking, family history, hypertension, hypercholestremia, dyslipidemiaand history of alcohol consumption and others were documented. Serum VD level was testedby blood samples from research laboratory of Liaquat Medical hospital Hyderabad, and all theresults were noted on the Performa according to the risk factors. Consequences of VD levelwere arranged by criteria, that’s taken from the study of Satish Karur etal.10 Results: Total 100patients were incorporated in the study with the mean age of 48.2+ 12.4. Male were found inthe majority. According to distribution of heart disease of his study ischemic heart disease hadnoted commonest58%. In the hypertensive patients VD deficiency had noted in 39. 63%. Insmoker patients VD deficiency was noted in 52.77%. In patients with hypercholestremia 50.0%,Alcoholic patients were found with deficiency of VD were 50.0%. In patients with obesity 57.14%.In the diabetic patients deficiency 15.0%, insufficiency 50.0% and sufficiency was seen 35.0%.In the Patients of dyslipidemia deficiency5.0%, insufficiency 50.0% and sufficiency was seen45.0%. Patients with family history of cardiovascular disease having deficiency 25.0% of thecases, insufficiency 12.50% while sufficiency in 62.50% in the cases. Conclusion: In this studywe concluded that VD deficiency in one of the major risk factor for cardiovascular disease;its possible association was found in this study with many risk factors of heart diseases. Likeour study there is very need of experimental and prospective more studies, to find out themechanism undergoing increasing cardiovascular risk, and prevent the cardiovascular disease.


2013 ◽  
Vol 33 (2) ◽  
pp. 121-124 ◽  
Author(s):  
Amar M Taksande ◽  
Krishna Vilhekar

Introduction: Congenital heart disease is the most common congenital problem that accounts for up to 25% of all congenital malformations. Hence this study was aimed at improving the knowledge related to risk factors associated with CHD in a rural Indian scenario. It was a hospital- based case control study. Materials and Methods: The children up to twelve year of age with clinical suspicion of CHD were subjected to chest x-ray and electrocardiography, and final diagnosis was confirmed by echocardiography (n=209) as cases. The control group (n=418) were randomly selected from children without CHD who were admitted during the same period. The etiological factors like environmental, infections, drugs, and maternal factors were analyzed by using EPI 6 version. Results: In cases group, 56% were male and 44% female children. 82% cases presented at age of less than 5 years and 18% after 5 year. Exposure to smoking (OR=10.45), tobacco intake by mother (OR=8.28) and family history of CHD (OR=7.21) were the significant risk factor present in cases. Conclusion: The risk factors for CHD child identified were exposure to smoking and tobacco intake by mother, family history of CHD, antenatal infection in 1st trimester and history of diabetic mother. DOI: http://dx.doi.org/10.3126/jnps.v33i2.8254   J Nepal Paediatr Soc. 2013; 33(2):121-124


2020 ◽  
Author(s):  
endang naryono

Covid-19 or the corona virus is a virus that has become a disaster and a global humanitarian disaster began in December 2019 in Wuhan province in China, April 2020 the spread of the corona virus has spread throughout the world making the greatest humanitarian disaster in the history of human civilization after the war world II, Already tens of thousands of people have died, millions of people have been infected with the conona virus from poor countries, developing countries to developed countries overwhelmed by this virus outbreak. Increasingly, the spread follows a series of measurements while patients who recover recover from a series of counts so that this epidemic becomes a very frightening disaster plus there is no drug or vaccine for this corona virus yet found, so that all countries implement strategies to reduce this spread from social distancing, phycal distancing to with a city or country lockdown.


2020 ◽  
Vol 18 ◽  
Author(s):  
Akshaya Srikanth Bhagavathula ◽  
Abdullah Shehab ◽  
Anhar Ullah ◽  
Jamal Rahmani

Background: The increasing incidence of cardiovascular disease (CVD) threatens the Middle Eastern population. Several epidemiological studies have assessed CVD and its risk factors in terms of the primary prevention of CVD in the Middle East. Therefore, summarizing the information from these studies is essential. Aim: We conducted a systematic review to assess the prevalence of CVD and its major risk factors among Middle Eastern adults based on the literature published between January 1, 2012 and December 31, 2018 and carried out a meta-analysis. Methods: We searched electronic databases such as PubMed/Medline, ScienceDirect, Embase and Google Scholar to identify literature published from January 1, 2012 to December 31, 2018. All the original articles that investigated the prevalence of CVD and reported at least one of the following factors were included: hypertension, diabetes, dyslipidaemia, smoking and family history of CVD. To summarize CVD prevalence, we performed a random-effects meta-analysis. Results: A total of 41 potentially relevant articles were included, and 32 were included in the meta-analysis (n=191,979). The overall prevalence of CVD was 10.1% (95% confidence interval (CI): 7.1-14.3%, p<0.001) in the Middle East. A high prevalence of CVD risk factors, such as dyslipidaemia (43.3%; 95% CI: 21.5-68%), hypertension (26.2%; 95% CI: 19.6-34%) and diabetes (16%; 95% CI: 9.9-24.8%), was observed. The prevalence rates of other risk factors, such as smoking (12.4%; 95% CI: 7.7-19.4%) and family history of CVD (18.7%; 95% CI: 15.4-22.5%), were also high. Conclusion: The prevalence of CVD is high (10.1%) in the Middle East. The burden of dyslipidaemia (43.3%) in this region is twice as high as that of hypertension (26.2%) and diabetes mellitus (16%). Multifaceted interventions are urgently needed for the primary prevention of CVD in this region.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Inés Urrutia ◽  
◽  
Alicia Martín-Nieto ◽  
Rosa Martínez ◽  
J Oriol Casanovas-Marsal ◽  
...  

AbstractThe aim of this study was to estimate the incidence of diabetes mellitus in the Basque Country and the risk factors involved in the disease by reassessing an adult population after 7 years of follow-up. In the previous prevalence study, 847 people older than 18 years were randomly selected from all over the Basque Country and were invited to answer a medical questionnaire, followed by a physical examination and an oral glucose tolerance test. In the reassessment, the same variables were collected and the resulting cohort comprised 517 individuals of whom 43 had diabetes at baseline. The cumulative incidence of diabetes was 4.64% in 7 years and the raw incidence rate was 6.56 cases/1000 person-years (95%CI: 4.11–9.93). Among the incident cases, 59% were undiagnosed. The most strongly associated markers by univariate analyses were age > 60 years, dyslipidaemia, prediabetes and insulin resistance. We also found association with hypertension, obesity, family history of diabetes and low education level. Multivariate analysis adjusted for age and sex showed that a set of risk factors assessed together (dyslipidaemia, waist-to-hip-ratio and family history of diabetes) had great predictive value (AUC-ROC = 0.899, 95%CI: 0.846–0.953, p = 0.942), which suggests the need for early intervention before the onset of prediabetes.


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