scholarly journals Pengaruh Perubahan Ritme Sirkadian terhadap Marker Inflamasi pada Pedagang Pasar Subuh di Kota Palangka Raya

2020 ◽  
Vol 5 (2) ◽  
pp. 92-99
Author(s):  
Rinny Ardina ◽  
Dwi Purbayanti
Keyword(s):  
Coronary Heart Disease ◽  
Platelet Count ◽  
Circadian Rhythm ◽  
Heart Disease ◽  
Sampling Technique ◽  
Cross Sectional ◽  
Distribution Width ◽  
Automated Method ◽  
High Platelet Count ◽  
Cross Sectional Design

Dawn market traders in Pasar Seram Palangka Raya City with sleep deprivation and alteration of sleep pattern has the potential risk of circadian rhythm disruption. Circadian rhythm disruption is the beginning of various chronic diseases such as coronary heart disease. One of the inflammation markers that can be used to assess the onset of atherosclerosis and coronary heart disease is the platelet profile (platelet count, mean platelet volume (MPV), platelet distribution width (PDW) and plateletcrit (PCT)). This study aimed to describe the effect of circadian rhythm disruption of inflammation marker as a platelet profile in dawn market traders in Pasar Seram Palangka Raya City. The descriptive observational method with a cross-sectional design was used in this study. Samples obtained as many as 100 people using purposive sampling technique. The examination of the platelet profile was done by an automated method using a hematology analyzer. The results showed, there was 6% with high platelet count and it only in women. Whereas for platelet indices in men, there was 6% with high MPV, 74% with high PCT, and 10% with low PCT. In women, there was 84% with high PCT and 6% with low PCT (6%). The result showed there were inflammation and accumulation of platelets as a result of circadian rhythm disruption in dawn market traders.

Hubungan Kadar Kolesterol Total Dan Hipertensi Dengan Kejadian Penyakit Jantung Koroner DI RSUD dr. Soedarso Pontianak

2018 ◽  
Vol 1 (2) ◽  
pp. 99
Author(s):  
Laila Kamila ◽  
Maulidiyah Salim
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Total Cholesterol ◽  
Blood Vessels ◽  
Public Hospital ◽  
Sampling Technique ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Purposive Sampling

Abstract: Coronary heart is a disease that offense to blood vessels and heart attack due to constriction of blood vessels. A high level of cholesterol in blood or exceeds the normal limit can form sediment in wall of blodd vessels which cause blood vessels constriction or blockage. This research object to determine whether there is a correlation between cholesterol level total and hypertension with coronary heart disease in patients who hospitalized in Regional Public Hospital of dr. Soedarso Pontianak. This study was used cross sectional design, purposive sampling technique, it gained 50 people as samples. The measurement of blood pressure was done in heart poly and cholesterol total level in clinic laboratory of Regional Public Hospital of dr. Soedarso by using enzymatic CHOD-PAP method. It can be obtained that 10 people had hypertension and 40 people did not.the average of total cholesterol was 224 mg/dl. Maximum value of total cholesterol was 224 mg/dl and 152 mg/dl as minimum value. Data has been analyzed by using statistical test, Chi-Square, to determine the correlation of total cholesterol wit coronary heart disease, obtained p value=0,024 (less than α=0,05). Correlation of hypertension and coronary heart disease gained p value=0,923 (more than α=0,05), it can be concluded that total cholesterol correlated with coronary heart disease, and there was not a correlation between hypertension and coronary heart disease.Abstrak: Jantung koroner adalah penyakit yang  menyerang pembuluh darah dan serangan jantung, karena penyempitan pada pembuluh darah. Kadar kolesterol yang tinggi dalam darah melebihi normal dapat membentuk endapan pada dinding pembuluh darah sehingga menyebabkan penyempitan dan tersumbatnya pembuluh darah. Penelitian ini bertujuan untuk mengetahui hubungan kadar kolesterol total dan hipertensi dengan penyakit jantung koroner pada pasien di RSUD dr. Soedarso Pontianak. Disain penelitian  ini menggunakan cross sectional, teknik pengambilan sampel yaitu purposive sampling, didapat jumlah sampel 50 orang. Pengukuran Tensi Darah dilakukan di poli Jantung dan pemeriksaan kadar kolesterol total di laboratorium klinik RSUD dr. Soedarso Pontianak dengan metode enzimatik CHOD-PAP. Hasil penelitian didapatkan 10 orang mengalami hipertensi dan 40 orang non hipertensi. Rata-rata kadar kolesterol total 224 mg/ dl. Nilai maksimum kadar kolesterol total yaitu 224 mg/dl dan nilai minimum yaitu 152 mg/dl. Analisa data dengan uji statistik Chi-square untuk mengetahui hubungan kolesterol total dengan penyakit jantung koroner didapatkan nilai p = 0,024 (lebih kecil dari  α 0,05). Uji hubungan hipertensi dengan penyakit jantung koroner didapat nilai p = 0,923 (lebih besar dari α 0,05), dapat disimpulkan terdapat hubungan kadar kolesterol total dengan penyakit jantung koroner dan tidak ada hubungan hipertensi dengan penyakit jantung koroner.

scholarly journals Is e-cigarette use associated with coronary heart disease and myocardial infarction? Insights from the 2016 and 2017 National Health Interview Surveys

2019 ◽  
Vol 10 ◽  
pp. 204062231987774 ◽  
Author(s):  
Konstantinos E Farsalinos ◽  
Riccardo Polosa ◽  
Fabio Cibella ◽  
Raymond Niaura
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
National Health ◽  
Pooled Analysis ◽  
Cigarette Use ◽  
Cross Sectional ◽  
Health Interview ◽  
Cross Sectional Design

Background: This study analyzed the National Health Interview Surveys (NHIS) of 2016 ( n = 33,028) and 2017 ( n = 26,742) to examine whether e-cigarette use is consistently associated with myocardial infarction (MI) and coronary heart disease (CHD). Methods: Surveys were examined separately and pooled. Logistic regression analysis was used, with demographics, e-cigarette use, smoking and risk factors for CHD (hypertension, hypercholesterolemia, and diabetes) being independent variables. Former smokers were subclassified according to quit duration (⩽ 6 and > 6 years). Results: For MI, an association was observed with some days e-cigarette (but not daily) use in the 2017 survey (OR: 2.11, 95% CI: 1.14–3.88, p = 0.017). No statistically significant association was observed in the pooled analysis (daily e-cigarette use: OR: 1.35, 95% CI: 0.80–2.27, p = 0.267). For CHD, an association was observed with daily e-cigarette use in the 2016 survey (OR: 1.89, 95% CI: 1.01–3.53, p = 0.047). From the pooled analysis, no association was found between any pattern of e-cigarette use and CHD. In single-year and pooled analysis, both MI and CHD were strongly associated with all patterns of smoking, hypertension, hypercholesterolemia, diabetes, and age. Conclusions: The pooled analysis of the 2016 and 2017 NHIS showed no association between e-cigarette use and MI or CHD. The associations between established risk factors, including smoking, and both conditions were remarkably consistent. The inconsistent associations observed in single-year surveys and the cross-sectional design of the NHIS cannot substantiate any link between e-cigarette use and an elevated risk for MI or CHD. Longitudinal studies are needed to explore the effects of e-cigarette use on cardiovascular disease.

scholarly journals Characteristic Comparison of CHD for Active Smoker by Smoking Characteristic

2017 ◽  
Vol 4 (3) ◽  
pp. 326
Author(s):  
Desy Diastutik
Keyword(s):  
Cardiovascular Disease ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Disease Duration ◽  
Communicable Disease ◽  
Disease Group ◽  
Cross Sectional ◽  
Active Smoker ◽  
Cross Sectional Design ◽  
Non Communicable Disease

Coronary Heart Disease (CHD) is a type of cardiovascular disease that has highest level of morbidity and mortality among non communicable disease group. One of the factor that contribute for coronary heart disease is smoking characteristic. The research was aimed to analyze characteristic comparison of coronary heart disease for active smoker by smoking characteristic. The research was observational study using cross sectional design. Thirty eight active smokers were involved as research sample who are patients at RSUD Sidoarjo, according to some criteria.The variables of smoking characteristic were duration of smoking, type of cigarette, amount of cigarette per day, and time of smoking. The research was done on May 2016 using accidental sampling as the technique. Data analyze was using Epi info software to show the characteristic comparison and continued analyze by descriptive. The results of the research were highest partly among patient with coronary heart disease and patient with non coronary diasease were had been smoking for ≥33 years, spent less than 13 cigarette per day, and didn’t smoke soon after wake up in the morning. The conclusion of the research are the highest characteristic coronary heart disease for active smoker by smoking characteristic was type of cigarette, and the lowest characteristic coronary heart disease for active smoker by smoking characteristic was duration of smoking.Keywords: number of cigarette, coronary heart disease, duration of smoking, type of cigarette, time of smoking

scholarly journals THE DESCRIPTION OF MODIFIABLE RISK FACTORS IN CORONARY HEART DISEASE AT DR. SOETOMO REGIONAL PUBLIC HOSPITAL

2019 ◽  
Vol 7 (2) ◽  
pp. 85
Author(s):  
Mayla Renata Sandi ◽  
Santi Martini ◽  
Kurnia Dwi Artanti ◽  
Sri Widati
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Public Hospital ◽  
Communicable Disease ◽  
Univariate Analysis ◽  
Sampling Technique ◽  
Primary Data ◽  
Modifiable Risk Factors ◽  
Cross Sectional

Background: Coronary heart disease (CHD) is a non-communicable disease that causes the highest mortality in the world, including in Indonesia. Risk factors for CHD are divided into modifiable and non- modifiable risk factors. Purpose: This study aims to discover the description of risk factors that are modifiable in coronary heart disease patients at Dr Soetomo Regional Public Hospital. Methods: It was a descriptive observational study with cross sectional study design. The study population was coronary heart disease patients who were doing outpatient treatment at the Integrated Heart Service Center (PPJT) of Dr. Soetomo Regional Public Hospital. The number of study sample was 72 respondents using accidental sampling technique. Data sources used are primary data using questionnaires and secondary data using medical record. Data were collected during November 2018. The location of this study was Dr. Soetomo Regional Public Hospital. The data analysis technique chosen was univariate analysis and presented in the form of a frequency distribution table. Results: The results of the study showed that the characteristics of respondents were mostly between 56-65 years old (43,05%) and male (70,84%). Risk factors found on the respondents were smoking (84,72%), hypertension (72,22%), hyperlipidemia (68,05%), diabetes mellitus (81,94%) and poor physical activity (77,77%). Conclusion: Modifiable risk factor that was mostly found on coronary heart patients was smoking, while least one was hiperlipidemia.

scholarly journals Faktor Dominan Risiko Terjadinya Penyakit Jantung Koroner (PJK)

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Ros Endah Happy Patriyani ◽  
David Ferry Purwanto
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Blood Vessels ◽  
Physical Inactivity ◽  
Serum Lipids ◽  
Dominant Effect ◽  
Cross Sectional ◽  
Cross Sectional Design ◽  
And Gender

Abstract: Risk Factors, CHD. Coronary Heart Disease (CHD) is the coronary atherosclerotic disease that causes narrowing of blood vessels. Constriction of blood vessels occurs because of atherosclerosis or spasm or a combination of both. the risk factors of CHD were divided into two, namely the factors that can not be changed and the factors can be changed. Factors that can not be changed include age, family history and gender. While the factors that can be changed include an increase in serum lipids (hyperlipidemia), personality type, smoking, impaired glucose tolerance (diabetes mellitus), lifestyle is less activity (physical inactivity), psychological stress, and hypertension. The purpose of this study to determine the risk factors that lead to increased incidence of coronary heart disease. The study is an observational analytic epidemiologic approach with cross sectional design with a sample of 40 respondents. The data analysis using logistic regression. The results showed the significant influence of CHD events by a factor of age> 40 years (p = 0.7370, hyperlipidemia (p = 0162), hypertension (p = 0365), smoking (p = 0153), as well as physical inactivity (p = 0535 ). Smoking is a risk factor most dominant effect on the incidence of CHD with OR = 4,500. the case studies are necessary to further research with a number of larger samples and develop variable-varabel to be studied is associated with other behaviors and lifestyles that affect developing CHD.

scholarly journals Hubungan periodontitis dengan penyakit jantung koroner pada pasien di RSUP Prof. Dr. R. D. Kandou Manado

e-GIGI ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Jolanda P. Ticoalu ◽  
Billy J. Kepel ◽  
Christy N. Mintjelungan
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Periodontal Disease ◽  
Systemic Disease ◽  
Case Control ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Cross Sectional Design

Abstract: Periodontitis is one of the factors causing systemic disease. It is often associated with increasing signs of inflammation and it is also an indicator of the risk factors of coronary heart disease (CHD). Infection of periodontal structures can accelerate the form of atherosclerosis that causes coronary heart disease due to systemic inflammation through the release of endotoxins, proteins, or acute phase reactors. This was a case control analytical study with a cross sectional design conducted at Prof. Dr. R. D. Kandou Hospital Manado from August to September 2016. There were 40 respondents (20 CHD patients and 20 non-CHD patients) obtained by using total sampling method. Periodontal disease indexes of the samples were evaluated by using periodontal disease index of Ramfjord 1959. The Chi-square test showed a p value of 0.01. Conclusion: There was a significant relationship between periodontitis and coronary heart disease in patients at Prof. Dr. R. D. Kandou Hospital Manado. Keywords: periodontitis, Coronary Heart Disease (CHD) Abstrak: Periodontitis merupakan salah satu faktor penyebab penyakit sistemik. Pada periodontitis sering didapatkan peningkatan tanda-tanda inflamasi yang juga merupakan salah satu indikator dari faktor risiko penyakit jantung koroner (PJK). Infeksi struktur periodontal dapat mempercepat pembentukan aterosklerosis yang menjadi penyebab PJK dengan cara menimbulkan inflamasi sistemik melalui pelepasan endotoksin, protein, atau reaktor fase akut. Jenis penelitian ialah analitik menggunakan case control dengan desain potong lintang. Penelitian dilakukan di RSUP Prof. Dr. R. D. Kandou Manado pada bulan Agustus sampai September 2016. Terdapat 40 responden (20 pasien PJK dan 20 pasien non PJK) diperoleh dengan menggunakan metode total sampling. Pada penelitian ini dilakukan pengukuran indeks penyakit periodontal menggunakan pengukuran PDI Ramfjord 1959. Analisis data menggunakan uji Chi-square. Hasil analisis bivariat menggunakan uji Chi-square menunjukkan nilai p=0,01 (0,01<0,05) yang menyatakan bahwa terdapat hubungan antara periodontitis dengan PJK pada pasien di RSUP Prof. Dr. R. D. Kandou Manado. Simpulan: Terdapat hubungan bermakna antara periodontitis dengan penyakit jantung koroner pada pasien di RSUP Prof. Dr. R. D. Kandou Manado.Kata kunci: periodontitis, penyakit jantung koroner (PJK)

scholarly journals Association of Fast Food Intake as a Risk Factor of Coronary Heart Disease in Male Population of Karachi, Pakistan

2020 ◽  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Food Intake ◽  
Fast Food ◽  
Dietary Habits ◽  
Strong Association ◽  
Sampling Technique ◽  
Middle Aged ◽  
Male Population ◽  
Cross Sectional

Objective: To determine the association of fast food intake and development of coronary heart disease with middle-aged men due to the nature of their job and eating habits. Methods: A cross-sectional study conducted among middle-aged males working in a different professional environment. The duration of the study was from March-October 2019. The calculated sample size was 385 and a Non-probability convenient sampling technique was used to collect data. Only Men aged 35-60 years of age working in different professional setups were included. Data was collected through a pre-structured questionnaire. Data was entered on IBM SPSS version 20. Results: The response rate to the survey was 85% while the completion rate of the survey was 94.5%. The mean age was 44.89 ±7.58 years having an average BMI of 25.94±3.89kg/m2. Out of these 311 men, 97.1% were a fast-food consumer. Fast food was more likely to be consumed by people who were doing a desk job than people whose nature was other than desk work (p=0.049). Among fast-food consumers, 40.7% had hypertension, 35.4% were obese, 22.5% had heart disease, and 21.9% had dyslipidemia. No significant association of heart disease (p=0.0689), obesity (p=1.00), hypertension (p=0.323) and dyslipidemia (p=0.213) was found with fast food consumption. Conclusion: Direct association between fast food and Coronary heart (CHD) disease is not significantly observed in the current study. However, dietary habits and the consumption of fast food have a profound effect on the development of predisposing factors of CHD. It is also concluded that long hours of desk job have a strong association with increased fast food intake due to its easy and quick availability within the short duration of time.

SOCIODEMOGRAPHIC RELATIONSHIP AND HISTORY OF CONCOMITANT DISEASES WITH CORONARY HEART DISEASE IN ACEH PROVINCE (SECONDARY DATA RISKESDAS 2018)

2021 ◽  
Vol 7 (1) ◽  
pp. 82-90
Author(s):  
Naimah Naimah ◽  
Asnawi Abdullah ◽  
Fahmi Ichwansyah
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Secondary Data ◽  
Provincial Government ◽  
Bivariate Analysis ◽  
P Value ◽  
Cross Sectional ◽  
Aceh Province ◽  
The Government ◽  
Cross Sectional Design

Background: Coronary Heart Disease (CHD) in Indonesia, especially Aceh Province, is the number one contributor to death at this time. The prevalence of CHD by province at the age ≥ 15 years was reported that Aceh ranks in the top two with the highest CHD provinces (D 0.7% and D/G 2.3%). This research needs to be analyzed further aimed to determine the determinants of CHD in Aceh Province because CHD in Indonesia is one of the main problems most noticed by the government. Various programs to anticipate and find solutions of health problems, especially CHD has beeen made for the good of the people of Indonesia. Methods: Further analysis of this secondary data is descriptive analytic using cross-sectional design. The research location in Aceh Province was conducted in May-June 2013. The secondary data was reprocessed by researchers in 2019. The population and samples in this study were 11.617 households and 40,951 household members. Data analysis was performed using univariate and bivariate analysis. Result: The results showed that there is a relationship between age and coronary heart disease (p value 0.001), gender (p value 0.001), low education level (p value 0.002), employment status (p value 0.008), Diabetes mellitus (p value 0.001), hypertension (p value 0.001), and smoking (p value 0.0001). Recommendation: It is hoped that the provincial government implements the No Smoking Area (KTR) policy in every public area such as schools, terminals, hospitals and create qanuns that truly public health precision.

scholarly journals KORELASI ANTARA RASIO NEUTROFIL LIMFOSIT DENGAN VOLUME INFARK SEREBRI PADA PENDERITA STROKE ISKEMIK AKUT

2020 ◽  
Vol 36 (4) ◽  
Author(s):  
Ilsa Hunaifi ◽  
Triana Dyah Cahyawati
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Infarct Volume ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Cross Sectional Design

 CORRELATION BETWEEN NEUTROFIL LIMPHOCYTE RATIO AND CEREBRAL INFARCTION VOLUME IN ACUTE ISCHAEMIC STROKEABSTRACTIntroduction: Inflammation plays a key role in stroke pathophysiology. Neutrophils is one of the earliest leucocyte subtypes to infiltrate the ischemia area of the brain. The neutrophil-lymphocyte ratio (NLR) is independent of the severity of coronary heart disease and as a predictor of poor clinical outcomes in patients with coronary heart disease undergoing angiography. The neutrophil-lymphocyte ratio values may be a prognostic factor in ischemic stroke patients. The neutrophil- lymphocyte ratio values can also be used in predicting infarct size, however limited study has been conducted in this area.Aim: To determine the correlation of NLR with cerebral infarct volume in acute ischemic stroke patients.Method: This was an analytical observational study with cross sectional design. The population for this study were acute ischemic stroke patients at NTB Genereal Hospital. The collected data were analyzed by Spearman correlation test.Results: Approximately 52 participants  were enrolled in this study with mean age was 59.79±8.65 years old. Hypertension was a common modifiable risk factor identified in more than 94.2 % participant. The mean of neutrophil lymphocyte ratio was 3.94±2.96 and mean of infarct volume was 13.96±37.26cm3. There was correlation between RNL and cerebral infract volume (r=+0.351; p=0.023).Discussions: Higher lymphocyte neutrophil ratio in acute ischemic stroke patients would result in an increase of brain infarct volume.Keyword: Infarct volume, ischaemic stroke, neutrophil lymphocyte ratioABSTRAKPendahuluan: Inflamasi memegang peranan penting dalam patofisiologi stroke. Salah satu subtipe dari sel leukosit yang paling awal menginfiltrasi ke area iskemia di otak adalah neutrofil. Rasio neutrofil limfosit (RNL) merupakan faktor independen terhadap beratnya penyakit jantung koroner dan sebagai prediktor luaran klinis yang buruk pada penderita penyakit jantung koroner yang menjalani angiografi. Nilai RNL dapat menjadi faktor prognostik pada penderita stroke iskemik. Nilai RNL juga bisa digunakan dalam memprediksi ukuran infark namun belum dilakukan penelitian hingga saat ini.Tujuan: Mengetahui korelasi RNL dengan volume infark serebri pada penderita stroke iskemik akut.Metode: Penelitian analitik observasional dengan desain potong lintang terhadap pasien stroke iskemik akut di RSUP NTB. Data yang terkumpul dianalisis dengan uji korelasi Spearman.Hasil: Didapatkan 52 subjek dengan rerata umur 59,79±8,65 tahun dan faktor risiko utama hipertensi (94,2%). Didapatkan rerata rasio neutrofil limfosit 3,94±2,96 dan rerata volume infark 13,96±37,26cm3. Terdapat korelasi antara RNL dengan volume infark serebri (r=+0,351; p=0,023).Diskusi: Semakin tinggi nilai rasio neutrofil limfosit mengakibatkan semakin luasnya volume infark serebri pada penderita stroke iskemik akut.Kata kunci: Rasio neutrofil limfosit, stroke iskemik, volume infark  

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