scholarly journals Multiple Myeloma - A hospital based cross sectional study in Bangladesh

2013 ◽  
Vol 38 (2) ◽  
pp. 189-198
Author(s):  
Subhagata Choudhury ◽  
Tanvira A Sultana ◽  
M Sirazul Islam ◽  
M Aminul Islam ◽  
Parvin A Khanam

Bone marrow morphological examination was performed on 835 patients either admitted in the inpatient departments of BIRDEM General Hospital or examined on outpatient basis. 760 of them were adults and 75 of them were children. 74 of the patients were diagnosed as suffering from a blood cancer known as Multiple Myeloma (MM). The age range of MM in our study was 40 to 85 years with a mean age of 63.25 years. Male to female ratio was 5:2 with a slight male preponderance. The median age of presentation was lower in females (60 years) than in males (65 years). MM was the second most frequent haematological disorder among all the patients examined, the most frequent one being leukemia. The frequency of MM was slightly higher among patients admitted in BIRDEM Hospital (10.4%) than those examined on outpatient basis (8.3%) although the difference was not statistically significant (P = 0.379 by Pearson’s Chi square test). The highest frequency of MM was found in patients admitted in the department of Orthopaedic Surgery (20.8%) followed by the Department of Nephrology (16.7%). This data represents a cross sectional picture of the prevalence of MM in elderly population. DOI: http://dx.doi.org/10.3329/jasbs.v38i2.15609 J. Asiat. Soc. Bangladesh, Sci. 38(2): 189-198, December 2012

2021 ◽  
Vol 5 (1) ◽  
pp. 018-021
Author(s):  
Gómez Elena ◽  
Guzmán Marianela ◽  
Torres Oriol Yuguero

Introduction: Psychiatric emergencies constitute between 1% - 10% of general emergencies in Spain, of which a quarter will end up being hospital admissions. There is little literature on patients who are referred from general to specialized hospitals. Methods: Cross-Sectional study of all the patients referred in 2018. Sociodemographic variables and clinical variables, such as diagnosis and discharge destination, were analyzed. An analysis was performed by comparing means with the Chi Square test. Results: 433 derived emergencies were analyzed. Most of the patients were women. The main reason for derivation were suicide attempts. Of those patients, 40% required hospitalizations. More than 50% of the derived emergencies were referred to the home and followed up on an outpatient basis. Conclusion: Most derived emergencies are referred to the home after evaluation. This implies that most are not life-threatening and that with adequate tools for evaluating suicide risk, we could avoid transfers and improve the resolution of these cases.


Author(s):  
Vikram Narang ◽  
Maneet Luthra ◽  
Avantika Garg ◽  
Amit Dhiman ◽  
Neena Sood

Introduction: Cytogenetics has become an integral part of Multiple Myeloma (MM) diagnosis and prognostication. A combination of conventional cytogenetics and interphase Fluorescence In Situ Hybridization (FISH) is currently used to stratify tumours into high, intermediate and standard risk disease. Aim: To compare the morphological details of plasma cells with cytogenetic abnormalities. Materials and Methods: The present retrospective cross sectional study was conducted at Department of Pathology Dayanand Medical College and Hospital, Ludhiana in three and a half year duration (1st January 2014 to 30th June 2017). All the diagnosed MM patients in whom cytogenetic was available were included and descriptive analysis was done using Chi-Square test and relevant statistical analysis using SPSS 21 version. Correlation was done with various morphological pattern (plasmacytic, plasma blastic). Results: Cytogenetic studies were performed on 42 cases using FISH technique (n=31, 81.6%) and GTG (Giemsa) banding (n=4, 10.5%). Three (7.9%) patients were tested with both methods. In the present study, all the patients (n=2,100%) with plasmablastic morphology who got tested with cytogenetics had del13q14.3 and none of the patients with normal genome (n=22) had plasmablastic morphology. Conclusion: Morphologic patterns of plasma cells and cytogenetic studies correlate well and can together help in better prognostication of MM patients.


2020 ◽  
Vol 8 (T1) ◽  
pp. 459-464
Author(s):  
Putri C. Eyanoer ◽  
Farhat Farhat ◽  
Elvita Rahmi Daulay ◽  
Fotarisman Zaluchu

BACKGROUND: In Indonesia, a new behavior has been introduced in the community to prevent COVID-19 transmission following 3 months of the COVID-19 outbreak. The Ministry of Health, Republic of Indonesia, names this new concept as “the adaptation of new behavior.” However, preventive measures and health protocols encouraged by the government have not yet yielded a significant impact on reducing the COVID-19 positivity rate. This unsuccessful outcome indicates that infective circulation is still occurring caused by incompliant to the health protocol. AIM: This study aimed to measure community perceptions against COVID-19 at the individual level. METHODS: A cross-sectional study with a total of 1687 respondents was performed. Questionnaires distributed thru sharing online links which contain questions on perception of vulnerability and severity of COVID-19. Chi-square test used in analysis to determine the difference in perception with respondents’ behavior. RESULTS: A total of 81.7% of respondents who had a perception of “susceptible to contract” performed behavior suited to recommendations and 81.2% study population had a perception of “COVID-19 is severe” executed behavior suited to the recommendation. CONCLUSION: This study demonstrated the establishment of government recommendations for COVID-19 infection did not guarantee the actual health practice/behavior in the community. The existing misconception of the perspective of seriousness/severity and susceptibility would prevent the country from flattening the curve.


2016 ◽  
Vol 14 (1) ◽  
pp. 33-39
Author(s):  
Ram Bilakshan Shah ◽  
Laxmi Subedi ◽  
Nilambar Jha

Introduction: Tobacco use is a global socio-economic hazard and medical malady. The incidence of tobacco is persisting and spreading in all walks of our modern society.Methods: The cross-sectional study was conducted among residents of Dhankuta Municipality where 205 households were taken as subjects. Pretested semi-structured questionnaire was administered to the study subjects and face to face interview was conducted. Chi-square test was applied to find out the association between pattern of tobacco use and awareness of tobacco use among residents of Dhankuta municipality.Results: The awareness towards tobacco use among residents of Dhankuta municipality was found to be 41 %. The awareness of tobacco consumption was significantly higher among the female (49 %) in gender and those whose education were School Leaving Certificate (SLC) and above (44.6 %) (P<0.05). The respondents consuming tobacco have forty times lesser chances of having aware as respondents not consuming tobacco (OR=0.025). The respondents consuming tobacco for more than 20 years (12.1 %) and more than 20 sticks per day (20 %) were more aware of tobacco consumption but the difference was not significant.Conclusions: The awareness towards tobacco use among residents of Dhankuta municipality was found to be less. Male in gender, lack of education and poor occupation like famer, housewife was found to be less aware of tobacco consumption. 


2020 ◽  
Vol 16 (3) ◽  
pp. 106
Author(s):  
Erizvina Marisa Anggraeni ◽  
Dewi Marhaeni Diah Herawati ◽  
Viramitha Kusnandi Rusmil ◽  
Tisnasari Hafsah

The differences of nutritional status of 6-9 months old infant given factory-made and homemade complementary foodsBackground: The nutritional status of 6-9 months old babies depend on the amount of nutrition acquired from breastmilk and complementary food. The incorrect feeding of complementary food may contribute to poor nutritional status. Objective: This study aims to illustrate the nutritional status of factory-made and homemade complementary food, and analyze the difference in the nutritional status of infants given factory-made and homemade complementary food.Methods: This is an analytic, observational, and cross-sectional study, conducted in seven villages within the scope of Puskesmas Jatinangor, Jatinangor Sub-district, Sumedang Regency in August-October 2018. The samples were 102 babies 6-9 months old obtained through total sampling. The variables of this study include the type of complementary food, and infant nutritional status with weight for age, length for age, and weight for height index.Results: Complementary food consumption is dominated by factory-made type (69.6%). Macronutrients which are energy and protein and micronutrients which are vitamins from both types of complementary food already fulfill the daily recommended dietary allowances for babies, except for minerals which are calcium, iron, and zinc. Chi-Square test results showed an insignificant difference in the nutritional status of babies (p=0,881 for BW/A; p=0.194 for BH/A; and p=0,599 for BW/BH) based on the type of complementary food given.Conclusions: Nutritional contents of macro and micronutrients from both types of complementary food have fulfilled the recommended dietary allowances for complementary food, except for the minerals calcium, iron, and zinc. There wasn’t a considerable difference in nutritional status between those acquired through factory-made and homemade complementary food.


2021 ◽  
Vol 53 (3) ◽  
pp. 138-142
Author(s):  
Hadi Susiarno ◽  
Ryandra Prakasa ◽  
Budi Handono

Urinary incontinence (UI) is a commonly overlooked problem in women, particularly women of post-menopausal age. Despite the medical, social, and hygiene burdens conferred by UI to its sufferers, past studies have shown that only a few among women afflicted with UI sought treatment. This may be due to various reasons: lack of knowledge and awareness of UI or a wrong belief of UI as a natural part of aging. This study aimed to investigate the association between knowledge and severity of UI and reasons for not seeking treatment among post-menopausal women in Bandung, Indonesia. This was an analytic cross-sectional study conducted at the Geriatric and Gynecology Clinic, Dr. Hasan Sadikin General Hospital, in September 2013. Ninety-one women who met the inclusion criteria were interviewed to assess their knowledge of UI. The severity of UI was assessed using Urinary Distress Inventory 6 (UDI-6). Data were analyzed using the chi-square test. Sixty-five respondents (70.7%) had poor knowledge of UI. Knowledge of UI was not associated with awareness of UI as a medical condition (p=0.633). The difference in UI severity was associated with the perception of UI as a normal part of aging (p=0.008). Post-menopausal women are poorly informed regarding urinary incontinence. However, knowledge alone might not be adequate to encourage women to seek treatment. Further studies are needed to investigate women’s reasons for not seeking treatment for UI.


2021 ◽  
Vol 3 (4) ◽  
pp. 293
Author(s):  
Nadya Khuswatun Khasanani ◽  
Ninik Darsini ◽  
Dwiyanti Puspitasari

Abstrak Latar belakang : Angka Kematian Bayi (AKB) yang tinggi masih menjadi permasalahan di Indonesia. Berbagai upaya telah dilakukan untuk menurunkan angka morbiditas dan mortalitas. Salah satunya dengan pemberian ASI eksklusif. Namun, cakupan ASI eksklusif di Indonesia masih belum mencapai angka yang diharapkan. Pada tahun 2017 cakupan pemberian ASI eksklusif di Surabaya terendah berada di Kelurahan Sidotopo Wetan, yaitu sebesar 51,94%. Penelitian ini bertujuan untuk mengetahui perbedaan frekuensi sakit bayi usia 6 – 12 bulan yang diberikan ASI eksklusif dan non ASI eksklusif. Metode : Jenis penelitian analitik observasional dengan rancangan penelitian cross-sectional. Sampel sejumlah 102 ibu yang memiliki bayi usia 6 – 12 bulan ( 53 bayi ASI eksklusif dan 49 bayi non ASI eksklusif). Sampling dengan cluster sampling. Variabel dependen adalah frekuensi sakit, variabel independen adalah bayi usia 6 – 12 bulan yang diberikan ASI eksklusif dan non ASI eksklusif. Instrumen yang digunakan adalah kuesioner. Analisis data menggunakan chi square(α = 0,05). Hasil : Bayi dengan ASI eksklusif sebagian besar memiliki frekuensi sakit yang jarang (79,2%), sedangkan bayi non ASI eksklusif sebagian besar memiliki frekuensi sakit yang sering (85,7%). Hasil uji chi square( p<0,001, OR=22,9), yang berarti bahwa terdapat perbedaan frekuensi sakit pada bayi usia 6 – 12 bulan yang diberikan ASI eksklusif dan non ASI eksklusif di Kelurahan Sidotopo Wetan, Surabaya. Kesimpulan : Bayi yang diberikan ASI eksklusif memiliki frekuensi sakit lebih jarang daripada bayi yang tidak diberikan ASI eksklusif.Abstract Background: High Infant Mortality Rate (IMR) is still a problem in Indonesia. Various efforts have been made to reduce morbidity and mortality. One of them is exclusive breastfeeding. However, the coverage of exclusive breastfeeding in Indonesia still has not reached the expected rate. In 2017 the lowest coverage of exclusive breastfeeding in Surabaya was in Sidotopo Wetan Village, which was 51.94%. This study aims to determine the difference frequency of illness in infants aged 6 - 12 months are given exclusive breastfeeding and non-exclusive breastfeeding. Method: Type of observational analytic study with cross-sectional study design. A sample of 102 mothers who had infants aged 6 - 12 months ( 53 infants exclusively breastfeeding and 49 infants non-exclusive breastfeeding). Sampling with cluster sampling. The dependent variable is the frequency of illness, the independent variable is infants aged 6 - 12 months are given exclusive breastfeeding and non-exclusive breastfeeding. The instrument used was a questionnaire. Data analysis using chi square (α = 0.05). Results: Most infants with exclusive breastfeeding had a rare frequency of illness (79.2%), while most non-exclusive breastfeeding infants had frequent frequency of illness (85.7%). Result of chi square test (p<0.001, OR=22,9),  which means that there were differences frequency of illness in infants aged 6-12 months were given exclusive breastfeeding and non-exclusive breastfeeding in Sidotopo Wetan Village.Surabaya. Conclusion: Infants are given exclusive breastfeeding have a less frequency of illness than infants are not given exclusive breastfeeding.


2020 ◽  
Vol 23 (2) ◽  
pp. 51-54
Author(s):  
Ervina Sofyanti ◽  
Mirna Rory Yohanita Tambunan ◽  
Trelia Boel ◽  
Darmayanti Siregar ◽  
Aditya Rachmawati

The examination of static and dynamic occlusal relationship are important in orthodontic diagnosis. Thus, this study aims to analysis the difference of occlusal cant and favored chewing side. This is cross-sectional study of 70 healthy dental students Universitas Sumatera Utara with complete dentition and have no orthodontics treatment history. The position of tongue spatula across on occlusal of both first bicuspids to assess the existence and degree of the canting occlusal based on extra-oral photograph. The occlusal cant positive if it coincided to inter pupil as transversal references and sectioned with facial midline as a vertical reference more than 3º. A modified direct method- visual observation was done to assess the favored chewing side. A chi-square test with p level 0.05 in evaluation of the null hypothesis that states there was a difference of occlusal cant and favored chewing side in those subjects. From 36 subjects with cant occlusal positive, there were 26 subjects with and 10 subjects without favored chewing side. Then, from 34 subjects with cant occlusal negative, there were 14 subjects with and 20 subjects without favored chewing side. There was a significant difference (p=0.017) between occlusal cant and favored chewing side. Subjects with complete teeth showed that favored chewing side tendency of 3,714 more often had an occlusal cant positive compared to favored chewing side negative. In conclusion, the significant difference of occlusal cant and favored chewing side in subjects with complete dentition can be considered as a preliminary study in order to understand the complexity of development of mandibular asymmetry.


2012 ◽  
Vol 8 (3) ◽  
pp. 113 ◽  
Author(s):  
Lucia Mawarti Dwi Astuti ◽  
Endy Paryanto Prawirohartono ◽  
Noormanto Noormanto ◽  
Madarina Julia

Background: Obesity in adolescents has become health problem in Indonesia. Central obesity is associated with insulin resistance.Theoretically, insulin resistance will cause impaired glucose tolerance (IGT) and could develop into type 2 diabetes.Objective: The aim of this study were to evaluate the difference in IGT prevalence between central and non central obesity and to identify the risk factors associated with IGT. Method: A cross sectional study was conducted at 3 private secondary schools in Yogyakarta and recruited 62 obese female students aged 12-18 years.The subjects were classified into central obesity (BMI/U> +2SD and waist circumference > p90) and non central obesity based on anthropometric data. Fasting glucose and 2 hours after loading were measured in all subjects. Differences in the proportion of IGT between the two groups was calculated by Chi-square test and risk factors associated with IGT were calculated by multivariate logistic regression with 95% confidence interval.Result: Of 62 subjects, 14 of them have IGT and the prevalence of IGT was significantly higher in the central obesity group compared to non central obesity group (11/31 vs 3/31, p=0.03). Central obesity was found to be the only risk factor of IGT (OR=4.6; 95%CI: 1.04 to 20.24). Twenty one of the subjects were found to have impaired fasting glucose (IFG) (34%) and one subject (1.6 %) had IFG+IGT. There were no differences in the proportion of IFG between central and non central obesity groups. Conclusion: The prevalence of IGT in female students with central obesity was higher compared to those with non central obesity. A female student with central obesity had 4.6-fold risk of having IGT compared to those with non central obesity.


2021 ◽  
Vol 15 (11) ◽  
pp. 2989-2992
Author(s):  
Abdul Haadi ◽  
Sidra Ishfaq ◽  
Munazza Nazir ◽  
Syed M.Sajid Ali Bukhari ◽  
Muhammad Ishraf-Ul-Islam ◽  
...  

Background: Evidence available on atrial fibrillation in Pakistan is not enough. Therefore, present study aims to determine frequency of atrial fibrillation and its associated complications. Place and duration of study: This cross sectional study was conducted at Department of Medicine, at SKBZ/AK CMH Muzaffarabad (Tertiary Care Hospital Muzaffarabad AJK) from July to December, 2019. Methodology: Total 1100 patients included for this study through non-probability consecutive sampling. Ethical approval and consent forms were taken. Patients were examined for atrial fibrillation through ECG. The patients who were confirmed as AF were detail examined and their cause and complications were noted down. Data was analyzed with SPSS version 24. One sample t test was used to predict AF in the population Chi-square test was applied. P value ≤0.05 was considered significant. Results: Out of 1100 patients mean age of patients was 43.4±12.7 years. The male to female ratio was 11:10. The atrial fibrillation was diagnosed in 250 (22.7%). In our population, at least 20% of the patients are having issue of atrial fibrillation with p value 0.016. The percentage of AF was higher in female 40.4% as compared to male 6.9%. Similarly the percentage of AF was higher in hypertensive patients (37.8%) as compared to non-hypertensive patients (12.3%). Conclusion:The prevalence of atrial fibrillation is moderately high in our data. Our sample results support the hypothesis that female are mostly with AF. Hence there is need to take measures to prevent them. Keywords: Atrial fibrillation, Causes of atrial fibrillation, Complications of atrial fibrillation


Sign in / Sign up

Export Citation Format

Share Document