scholarly journals Clinico-Biochemical Abnormalities in Hospitalized Neonates with or without Seizure

2020 ◽  
Vol 32 (1) ◽  
pp. 37-41
Author(s):  
Shah Muhammad Masuduzzaman ◽  
Md Nazrul Islam ◽  
Md Abid Hossain Mollah ◽  
Mohammad Azizul Hoque ◽  
Md Anwar Hossain ◽  
...  

Introduction: To determine the clinical types and etiological factors and to assess the biochemical abnormalities in neonates with seizure. Materials and Methods: This was a Cross-sectional, comparative hospital based study. Ninety neonates, age up to 28 days of both sexes were evaluated for clinical types, etiological factors and biochemical abnormalities with seizure and compared with those having no seizures. The variables were analyzed using student t- test. All the data was processed and analyzed by computer software SPSS version 15.0. Level of significance was considered as p value less than 0.05. Results: Most of the neonates having seizures (72%) within 3 days of life. The seizures were common in male babies (62%). 35% of the mother of baby with seizure gave history of prolonged labour. HIE was diagnosed 56.67% neonates with seizure whereas infection were found in 25% cases with seizure. Among the seizure subtypes, subtle seizures were 58% followed by clonic seizures 30%. Significant biochemical changes we found in 43.34% of neonates with seizures. Hypocalcemia (46%) was most common followed by hypoglycemia(38%). Conclusion: Hypoxic ischemic encephalopathy was the commonest cause of neonatal seizure followed by neonatal infections including meningitis and sepsis.. Biochemical abnormalities are more common in neonates with seizure than neonates free from seizure. Among the biochemical abnormalities hypocalcaemia and hypoglycemia occurs most commonly followed by hyponatraemia and hypomagnesaemia. Medicine Today 2020 Vol.32(1): 37-41

2020 ◽  
Vol 14 (2) ◽  
pp. 55-57
Author(s):  
NP Biswas ◽  
MS Islam ◽  
MZ Hossain ◽  
MH Uddin ◽  
MA Kashem ◽  
...  

Purposes: To compare the efficacy of ultrasound and CT scan in renal tumour evaluation and to establish by subsequent histopathology. Introduction : Renal cell carcinoma accounts for about 3 % of all adult neoplasms. In detecting, characterizing and staging of renal tumours cross-sectional imagings are essential. Methods: In this study 36 cases were selected nonrandomly irrespective of age and sex according to selection criteria. The study was conducted from June 2006 to May 2007 in Banga Bandhu Sheikh Mujib Medical University and other Hospitals in Dhaka City in the department of urology on a quasi- experimental basis. After counselling and taking consent all patients were evaluated clinically and by ultrasound and CT scan. All patients underwent surgery followed by histopathology. All informations were collected in a predesigned data collection sheet. Data were analyzed by computer software program-SPSS version 12 and by manual technique. Comparison and correlation between Ultrasonogram and CT findings were done by Chi-square test. Level of significance was expressed as P-value. Results: Among 36 patients 21 were male and 15 female with a ratio of 1.4:1, age ranging from 3 to 73 years. In this study (from the data) 94.44%, 33.33%, 89.74% and 100%, 66.66% 97.43% respectively. And there was no statistical significance between these two imaging findings in renal tumour evaluation and P- Value was > 0.10 so it was not Significant. Conclusion : Ultrasonogram and CT Scan are near equivalent to each other evaluation of renal tumour. Bangladesh Journal of Urology, Vol. 14, No. 2, July 2011 p.55-57


2021 ◽  
Vol 11 (5) ◽  
pp. 261-268
Author(s):  
Manju Nepal ◽  
Bandana Pokharel ◽  
Parbati Nepal

Objective: Cardiovascular diseases (CVD) are the leading cause of death worldwide. It is crucial to detect risk factors and behaviors throughout childhood and adolescence to advocate as a strategy to reduce risk of CVD in adulthood. The objective of this study was to assess the awareness and attitude regarding Cardiovascular Diseases among the Adolescents Studying in Grade 12 in Makawanpur Multiple Campus in Nepal. Materials and Methods: This descriptive cross sectional analytical study was conducted among 135 adolescents studying in grade 12 in Makwanpur Multiple Campus, Hetauda, Nepal. The selection of study site was done purposively. A structured self-developed questionnaire was used to assess the awareness on cardiovascular disease and five-point Likert scale to assess attitude regarding cardiovascular diseases were used. Statistical package for social sciences (SPSS) version 20 was used for data analysis. Both descriptive (frequency, percentage, and mean) and inferential statistics (chi-square) were used to analyze the data. Results: Among 135 respondents, 17(12.6%) respondents had inadequate awareness, 52(38.5%) had moderate awareness and 66(48.9%) had adequate awareness. The mean awareness on cardiovascular disease was 11.90±2.83. Similarly more than half of respondents 69(51.1%) had favorable attitude toward cardiovascular disease. A statistically significant association between gender of the respondents and awareness level was found as Chi-square p value less than 0.05 (p=.011) at 5% level of significance. Similarly, statistically significant association between family history of CVD and attitude on cardiovascular disease was found at 5% level of significance (p value=.027). Conclusion: Nearly half of respondents had adequate level of awareness regarding cardiovascular diseases whereas more than half of respondents had favorable attitude toward cardiovascular disease. Key words: Adolescent, Attitude, Awareness, Cardiovascular Diseases.


2013 ◽  
Vol 25 (1) ◽  
pp. 21-24 ◽  
Author(s):  
MAH Khan ◽  
Ishaque Majumder ◽  
M Hoque ◽  
M Fariduddin ◽  
FH Mollah ◽  
...  

Hypothyroidism is an important metabolic disorder and is associated with many biochemical abnormalities. Many studies were done regarding the biochemical status of hypothyroid patients including lipid profile. But controversies still prevail. So, a cross sectional study was done in our population to evaluate lipid profile status of hypothyroid patients compared to age and sex matched healthy euthyroid persons. In our study mean serum total cholesterol, LDL cholesterol and triacylglycerol levels in cases and controls were 241.56 ± 60.05 vs 146.94 ± 23.21 mg/dL, 151.96 ± 59.60 vs 71.43 ± 26.83 mg/dL and 212 ± 100.73 vs 98.87 ± 39.69 mg/dL respectively with p values < 0.001 whereas HDL cholesterol was found significantly decreased in cases compared to controls (49.59 ± 11.69 vs 55.89 ± 11.70 mg/dL with p value < 0.05). Results of our study suggest that dyslipidemias are associated with hypothyroidism. Therefore, patients presenting with dyslipidemia are recommended for investigation to explore hypothyroidism DOI: http://dx.doi.org/10.3329/medtoday.v25i1.15904 Medicine Today 2013 Vol.25(1): 21-24


Author(s):  
Brain Guntoro ◽  
Kasih Purwati

Hypertension is one of the number one causes of death and disability in the world. Hypertension contributes nearly 9.4 million deaths from cardiovascular disease each year. Hypertension can cause undesirable effects, it needs good handling, one of them is by doing a hypertension diet. To carry out a hypertension diet requires knowledge, lack of knowledge can increase risk factors for hypertension. This study aims to determine the relationship of the level of knowledge about hypertension diet to the incidence of hypertension in the elderly at the Baloi Permai Public Health Center Batam City. This research method is an analytic observational with a cross-sectional approach conducted at the Baloi Permai Public Health Center Batam City 2018. Sampling technique is a total sampling with a sample of 64 people in 2018 determined by inclusion and exclusion criteria. The results of the study were analyzed with frequency distribution and then tested with the Chi-square test. Based on the results of this study indicate that of the 64 respondents found elderly who have a good level of knowledge are 41 people (64.1%), 48 people (75.0%) have an age range between 60-70 years. 27 people (42.2%) elderly have the last high school education and 40 people (62.5%) have jobs as entrepreneurs. Elderly people who have normal blood pressure are 40 people (62.5%), and those affected by hypertension are 24 people (37.5%). The elderly who have a family history of hypertension is 21 people (32.8%) and those who do not have a history of hypertension are 43 people (67.2%). Chi-Square Test analysis results show the significance value p = 0.009. This number is significant because the p-value is smaller than the significance level (α) ≤ 5% (0.05), so H0 is rejected and Ha is accepted. Therefore it can be concluded that there is a significant relationship about the level of knowledge about the hypertension diet to the incidence of hypertension in the elderly. From the results of this study it was concluded that there was a relationship between the level of knowledge about the hypertension diet and the incidence of hypertension in the elderly at the Baloi Permai Public Health Center Batam City in 2016.


2020 ◽  
Vol 4 (3) ◽  
pp. 100-111
Author(s):  
Vita Camelia ◽  

Stunting is a children growth problem that occurs a result of chronic malnutrition in the first 1000 days of life. The indicator of stunting is using the height measurement according to age HFA (Height for Age) under -2 SD based on the WHO growth standard curve according to sex. The impacts of stunting are the occurrence of growth disorders, barriers to development and the risk of metabolic disorders in adulthood. One of the risk factors for stunting is history of quality and quantity Antenatal Care (ANC). This study aimed to determine the relationship between quality and quantity history of ANC visits and stunting in toddlers aged 24-59 years in Pujon District Malang Regency. The method used in this research was observational analytic by using cross-sectional design. The population of this study was all mothers who have children aged 24-59 months that were conducted in January 2020. Ninety eight respondents taken by purposive sampling as the sample of the research. The data was obtained by filling out questionnaires and KIA books, then analyzed with chi-square test (α = 0.05). The results showed that there was a significant relationship in quality (p-value = 0.004) and quantity (p-value = 0.003) toward stunting.


Author(s):  
Etienne Belinga ◽  
Isidore Tompeen ◽  
Claude Cyrille Noa Ndoua ◽  
Junie Metogo Ntsama ◽  
Sandrine Mendibi ◽  
...  

Background: Uterine synechiae refers to a total or partial union of the inner walls of the uterus resulting from endometrial trauma. It is a cause of reproductive failure. Until now, synechia was not optimally treated and has remained understudied in Cameroon. Objective of present study was to Evaluate the diagnostic, therapeutic and prognostic aspects of uterine synechiae treated by hysteroscopy.Methods: We conducted a descriptive cross-sectional study with an analytical component from January 1st 2015 to July 31st 2017 at Yaounde. All patients diagnosed with uterine synechiae and treated with hysteroscopy were our sample. Sampling was consecutive. The chi-square test was used for the comparison of qualitative variables and Fisher's test for ANOVA variance analysis. The comparison of the averages was made by the Student's test. P-value less than 0.05 was considered as statistically significant.Results: Hysteroscopies were indicated for uterine synechiae in 14.50%. Nulliparous were 56.67%. A history of curettage/aspiration was present in 66.66%. All of the patients had a form of infertility and 83.33% had menstrual disorders. Hysterosalpingography showed a better sensitivity (88%). After hysteroscopic treatment, 63.30% had a complete anatomical restitution. There is a significant correlation between the stage of severity of synechia and anatomical restitution (p=0.008; Spearman correlation coefficient=-0.477).Conclusions: Uterine synechiae represent one-sixth of all indications for hysteroscopy and present clinically as menstrual disorder associated with infertility. A past history of uterine curettage is common. Hysterosalpingography has a better preoperative diagnostic sensitivity. Hysteroscopy allows optimal treatment.


2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Fatma Al Hoqani ◽  
Wadha Al Ghafri ◽  
Saneya El tayeb ◽  
Yahya Al Farsi ◽  
Vaidyanathan Gowri

Objective: to determine the prevalence of explained and unexplained recurrent miscarriages (RM) and to find out if there is a significant relationship between recurrent miscarriages and consanguinity. Methods: A cross sectional in which the cases group included all women with RM attending the outpatient clinic at Sultan Qaboos University Hospital from July 2006 to April 2012 and the controls group included women with no history of RM after matching them with cases for age (case to control ratio was 1:1). The main outcome measures were the prevalence of consanguinity in women with or without recurrent miscarriages. Results: During study period a total of 290 women with RM were seen. Of which, 150 (51.7%) women had unexplained RM. Control group with no history of RM were 300 women. Consanguinity rate among cases (49.5%) %) was less than the controls (52.7 %%). Both first cousin and second cousin marriages were more common in the controls than the cases and it was not statistically significant (p value 0.476, chi squared test). Conclusion: In this study we found that more than half of RM cases were unexplained and there was no significant association between RM and consanguinity.


2020 ◽  
Vol 7 (11) ◽  
pp. 1626
Author(s):  
Ivany Lestari Goutama ◽  
Hendsun . ◽  
Yohanes Firmansyah ◽  
Ernawati Su

Background: Cardiovascular relative risk (CVRISK) is the latest cardiovascular relative risk score to evaluate the magnitude of cardiovascular risk in healthy people regardless of age and cardiovascular risk severity. The aim of the study is to determine the correlation between each independent variables of CVRISK score in individuals with and without history of cardiovascular diseases (CVD).Methods: The study design is cross-sectional study. We conducted it online through social media using Google forms from June to August 2020. Participants include all productive age groups from 16 to 60 years. The data were processed using excel and statistically tested. Descriptive data analysis uses tabulated data which is displayed in numbers or proportions (categorical) and single data distribution (numeric). Statistical association analysis uses the categorical-correlation test with 2 statistical tests that use eta on nominal-ordinal variables and contingency coefficients on nominal-nominal variables.Results: There is a strong autocorrelation between hypertension and high tryglyceride levels (p value 0.001; correlation 0.549; risks 30.14%), nutritional status and low-density lipoprotein cholesterol (LDL-C) levels in CVD group (p value 0.002; correlation 0.774; risks 59.90%) and non-CVD group (p value 0.000; correlation 0.757; risks 57.3%). Hypertension and risky LDL-C levels firmly proves a very strong correlations and significant relationship in CVD groups (p value 0.014; correlation 0.947; risks 89.68%).Conclusions: There is a correlation that varies from weak to very strong among the independent variables in the CVRISK scoring of the participants. Further research is needed to determine the potentiality of CVRISK as an early prevention in determining the cardiovascular risk of individuals with and without history of CVD.


2012 ◽  
Vol 18 (2) ◽  
pp. 103-108
Author(s):  
Mohammad Nasimul Jamal ◽  
Ali Imam Ahsan ◽  
Mohammed Sattar ◽  
Md Abul Hasnat Joarder

Introduction: Deafness is the invisible disability and the commonest human sensory defects.  It leads to difficult speech development, poor educational and employment prospects of  chilhood. Comprehensive otologic and audiological evaluations are very much essential for  etiological assessment of hearing impaired children and management efficacy.Methods: A cross-sectional study was carried out with the aim to evaluate the etiological  factors, degree of hearing loss, type of hearing loss, and results of aided audiogram among  the below 12 years deaf children. The study included 100 deaf children below 12 years with  history of deafness and non-development of speech.Result: The etiology of deaf Children was diverse. Infection was the predominating etiological  factor (38%). The infections were: measles (31.5%), pneumonia (26.2%), typhoid (21.5%),  maternal rubella (5.2%), varicella (5.2%), mumps (5.2%) and meningitis (5.2%). 48% of deaf  child had a parental suspicion of deafness below the one year of age. 35% had a positive  family history and 32% had history of consanguinal marriage. The deaf children were managed  with hearing device, among them 89% with hearing aid and 11% with cochlear implant 42.7% of child used hearing aid in both ears. The results of aided audiogram reflected that, the gain  after using hearing aid within 31-60 dB were 80%. 10% in right ear, 71.10% in left year and  70.00% in both ears, so average gain after using hearing aid was 74% within 31- 60 dB. DOI:http://dx.doi.org/10.3329/bjo.v18i2.11981 Bangladesh J Otorhinolaryngol 2012; 18(2): 103-108


2020 ◽  
Author(s):  
Yigrem Ali Chekole

Abstract Introduction Compared to other deadly communicable diseases, Psychoactive Substance use is among the leading cause of death. Repeated use linked to addiction, dependence and predisposition for criminal and antisocial behaviors. Even though drug use in Africa relatively is short; however the abuse of drug in Africa is escalating rapidly. Substances use is also one of the most burning and growing public health problems in Ethiopia, as in many developing countries; alcohol is the most frequently used substance. Objective To Assess the Prevalence of alcohol Use and Associated factors among Dilla University undergraduate students in Southern Ethiopia. 2018. Methods An Institution based cross -sectional study was conducted at Dilla University among undergraduate regular students from January-February. Systematic random sampling technique was used to get a total of 803 samples of students from each year and department of the university. The collected data was coded, entered in to EPI-INFO version7.1 and analyzed by using SPSS version 20. Crude and adjusted OR were analyzed using logistic regression and the level of significance of association was determined at P- value <0.05. Result A total of 803 participants were interviewed with a response rate of 91.7%. Among the Participants, alcohol use was found to be 67.6%. (41.8%; n=336). Being 4 th year students (AOR =2.66, 95% CI: 1.64, 4.31), having friends who use substance (AOR=1.53, 95% CI: 1.09, 2.1), being Khat user (AOR= 1.48, 95% CI: 1.05, 2.09) and being Cigarette smoker (AOR=1.76, 95% CI: 1.09, 2.84) were found to be significantly associated with alcohol use. Conclusion Half of the participants found to have alcohol use. Therefore, early prevention, detection and alleviating of alcohol use should be implemented among students in the university.


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