Platelets Are Critical Key Players in Sepsis
2019 ◽
Vol 20
(14)
◽
pp. 3494
◽
Keyword(s):
Host defense against infection is based on two crucial mechanisms: the inflammatory response and the activation of coagulation. Platelets are involved in both hemostasis and immune response. These mechanisms work together in a complex and synchronous manner making the contribution of platelets of major importance in sepsis. This is a summary of the pathophysiology of sepsis-induced thrombocytopenia, microvascular consequences, platelet-endothelial cells and platelet–pathogens interactions. The critical role of platelets during sepsis and the therapeutic implications are also reviewed.
2000 ◽
Vol 15
(1)
◽
pp. 24-31
◽
2019 ◽
Vol 18
(1)
◽
pp. 78-87
◽
Keyword(s):
2018 ◽
Vol 315
(5)
◽
pp. H1477-H1485
◽
Keyword(s):
2020 ◽
Vol 1
(9)
◽
pp. 64-71
2002 ◽
Vol 277
(36)
◽
pp. 32546-32551
◽