scholarly journals Phytochemistry, Pharmacology, and Nutraceutical Profile of Carissa Species: An Updated Review

Molecules ◽  
2021 ◽  
Vol 26 (22) ◽  
pp. 7010
Author(s):  
Jyoti Dhatwalia ◽  
Amita Kumari ◽  
Rachna Verma ◽  
Navneet Upadhyay ◽  
Ishita Guleria ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Review Article ◽  
Bioactive Constituents ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Evergreen Species ◽  
Tropical Regions ◽  
Stomach Pain ◽  
Indigenous Uses ◽  
Micro Elements

Carissa, a genus of the Apocynaceae family, consists of evergreen species, such as shrubs as well as small trees that are native to Asia, Africa, and Oceania’s subtropical and tropical regions. Most of the Carissa species are traditionally used to treat various diseases, such as chest pain, headaches, gonorrhoea, rheumatism, syphilis, oedema, rabies, stomach pain, hepatitis, cardiac diseases, and asthma. The pharmacological studies on Carissa species revealed its antioxidant, antimicrobial, anticancer, cardioprotective, antipyretic, analgesic, wound healing, anticonvulsant, antiarthritic, adaptogenic, anti-inflammatory, and antidiabetic activities, thus validating its use in indigenous medicine systems. The review article summarised the comprehensive literature available, including morphology, indigenous uses, bioactive composition, nutraceutical, and pharmacological activities of Carissa species. A total of 155 research papers were cited in this review article. The Carissa fruits are rich in dietary fibre, lipids, proteins, carbohydrates, vitamin C, and macro- and micro-elements. A total of 121 compounds (35 polyphenols (flavonoids and phenolic acids), 30 lignans, 41 terpenoids, 7 steroids, 2 coumarins, and 6 cardiac glycosides) have been extracted from C. spinarum, C. carandas, and C. macrocarpa. Among all chemical constituents, lupeol, carissol, naringin, carisssone, scopoletin, carissaeduloside A, D, J, carandinol, sarhamnoloside, carissanol, olivil, carinol, 3β-hydroxyolean-11-en-28,13β-oilde, ursolic acid, and carissone are the key bioactive constituents responsible for pharmacological activities of genus Carissa. The gathered ethnopharmacological information in the review will help to understand the therapeutic relevance of Carissa as well as paving a way for further exploration in the discovery of novel plant-based drugs.

Phytochemical and Pharmacological Review on Two Herbs of Baijiangcao: Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss

2020 ◽  
Vol 17 (5) ◽  
pp. 496-517
Author(s):  
Yangcheng Liu ◽  
Wei Liu ◽  
Jiaqi Wang ◽  
Yang Liu ◽  
Changlan Chen ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Volatile Components ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Comprehensive Review ◽  
Scientific Databases ◽  
The Past ◽  
Current State ◽  
Patrinia Scabiosaefolia ◽  
Antiviral Activities

Patrinia scabiosaefolia Fisch. Trev. and Patrinia villosa (Thunb.) Juss, are two species of Patrinia recorded in the Chinese Pharmacopoeia with the same Chinese name “Baijiangcao” and similar therapeutic effect in traditional Chinese medicine. The present article is the first comprehensive review on the chemical composition and pharmacological activities of these herbs. In this review, data on chemical constituents and pharmacological profile of the two herbs are provided. This review discusses all the classes of the 223 compounds (phenylpropanoids, flavonoids, terpenes, saponins and volatile components, etc.) detected in the two herbs providing information on the current state of knowledge of the phytochemicals present in them. In the past three years, our research group has isolated and identified about more than 100 ingredients from the two herbs. Therefore, we published a systematic review of our research papers and studies on the two herbs were carried out using resources such as classic books about Chinese herbal medicine and scientific databases including Pubmed, Web of Science, SciFinder, CNKI. etc. The present review discusses the most thoroughly studied pharmacological activities (antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, antitumor and antiviral activities) of the two herbs. This comprehensive review will be informative for scientists searching for new properties of these herbs and will be important and significant for the discovery of bioactive compounds from the two herbs and in complete utilization of Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss.

scholarly journals Review Based Upon Ayurvedic and Traditional Uses of Cinnamomum tamala (Tejpatta)

2021 ◽  
Vol 68 (2) ◽  
Author(s):  
Shifali Thakur ◽  
Gitika Chaudhary
Keyword(s):  
Chemical Constituents ◽  
Bioactive Constituents ◽  
Pharmacological Activities ◽  
The Past ◽  
Cinnamomum Tamala ◽  
Medicinal Use ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents ◽  
Herbal Plant ◽  
Flavoring Agent

Cinnamomum tamala is an evergreen plant native to Sri Lanka and India. This herbal plant is commonly called Indian cassia, Tejpatta and Indian bay leaf. There are many bioactive constituents isolated from plant Cinnamomum tamala. Leaves of the plant possess aromatic fragrance and are also utilized as a flavoring agent. It is used in food curry, pickles and other spices. Besides food application, the leaves have also been used for curing a number of ailments. All parts of the plant possess many major bioactive chemical constituents like cinnamaldehyde, trans-cinnamaldehyde, 3,4,5,7- tetrahydroxyflavone, 3,3,4,5,6- pentahydroflavone (non-glycoside compounds), kaempferol, eugenol, etc. These phytochemical compounds have many pharmacological activities such as anticancer, antidiabetic, antimicrobial, hepatoprotective, antidiarrheal and immunomodulatory. In the past time, it is also considered for medicinal use. Their medicinal use was also mentioned in the literature of ayurveda, yunani and other traditional systems of medicine. Due to aromatic fragrance, it is also utilized in the perfume industry. The major aim of this review is to give a brief knowledge about the plant Cinnamomum tamala based on their phytochemical constituents, ayurvedic view, folk view and pharmacological application.

scholarly journals An Invasive Yet Potentially Diverse and Unexplored Genus: Typha L.

2021 ◽  
pp. 182-194
Author(s):  
Vidhi Makwana ◽  
Abhaykumar Kethwas ◽  
Niravkumar Sapoliya ◽  
Krupa Limbachiya ◽  
Sanjay Gamit ◽  
...  
Keyword(s):  
Biological Diversity ◽  
Review Article ◽  
Literature Survey ◽  
Invasive Weeds ◽  
Pharmacological Activities ◽  
Tropical Regions ◽  
The Family ◽  
America South ◽  
Maximal Benefit ◽  
Active Substances

Aim: Typha genus belongs to the family Typhaceae and is comprising of about 13 known species distributed in the subtropical and tropical regions of North America, South America, Asia, Africa, Australia and Europe. Several species are considered as invasive weeds that colonize wetlands and marshes because they are highly productive by clonal growth, forming very large, persistent and often monospecific stands. This review offers detailed information on the aquatic species of the cosmopolitan genus Typha L. with specific focus on their distribution, identification, importance in bioremediation, usability and traditional uses along with chemical and biological diversity. Methodology: An extensive browsing in three electronic databases (Unbound Medline, PubMed and ScienceDirect) and internet search engines (Scifinder and Google Scholar) enabled us to connote the studies on Typha genus available till date. Results: Literature survey corroborated that some species of Typha are valuable as sources of traditional medicine in human health, while some are still widely used for non-pharmacological purposes. Numerous phytochemical investigations of plants of this genus confirmed the presence of alkaloids, glycosides, tannins, steroids, phenols, saponins, flavanoids, carbohydrates, proteins, oils and fats. Besides, various studies cited in this review article have demonstrated that the extracts or active substances that have been isolated from the species of Typha genus have multiple pharmacological activities. Conclusion: The review draws the attention of scientists towards the utility and important issues associated with the probable approaches that should be investigated to encourage people to take maximal benefit of the potentially useful species of Typha genus.

scholarly journals A Review on Chemical Constituents, Traditional Uses, Pharmacological Studies of Zanthoxylum armatum (Rutaceae)

2021 ◽  
Vol 11 (2-S) ◽  
pp. 136-142
Author(s):  
Kapil Kumar Verma ◽  
Bhopesh Kumar ◽  
Hans Raj ◽  
Akanksha Sharma
Keyword(s):  
Carbonyl Compound ◽  
Chemical Constituents ◽  
Review Article ◽  
Linalyl Acetate ◽  
Pharmacological Activities ◽  
Zanthoxylum Armatum ◽  
Ancient Time ◽  
Traditional Uses ◽  
Pharmacological Studies ◽  
Important Evidence

Zanthoxylum armatum used as a medicine from ancient time for cure of various diseases such as toothache and problems related to tooth, asthma, used for gum bleeding, fever, dyspepsia, and tonics etc. Phytochemistry, pharmacological activities, diseases, traditional uses etc are explained in this review article .This article have information of the Z. armatum which may have  Phytochemistry, pharmacological activities, diseases, traditional uses etc. Some latest info of Phytochemistry, pharmacological activities, diseases, traditional uses may show clearance in review. Different activities of various diseases known as antioxidants, antinociceptive, antifungal, antinflammtory, hepatoprotective, pesticides, anthelminitic, antiproliferative etc including chemical constituents like resins, 1-alphaphellandrene, linalool, carbonyl compound, methyl n-nonylketone. Linalyl acetate, sesquiterpene, hydrocarbon, tricosaine, dictamine, fragarine, magnoflorine, skimmianine, xanthoplanine. It is expected that more investigation on plant can be done. This review article is helpful to get various important evidence regarding the plant Zanthoxylum armatum which will works as key point for the future investigation. Keywords: Z.armatum, Phytochemistry, traditional uses, pharmacological activities.

Adhatoda vasica (Nees.): A review on its botany, traditional uses, phytochemistry, pharmacological activities and toxicity

2021 ◽  
Vol 21 ◽  
Author(s):  
Tahmida Shamsuddin ◽  
Muhammad Shaiful Alam ◽  
Md. Junaid ◽  
Rasheda Akter ◽  
S. M. Zahid Hosen ◽  
...  
Keyword(s):  
Whooping Cough ◽  
Chemical Constituents ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Tropical Zone ◽  
Adhatoda Vasica ◽  
Scientific Databases ◽  
Traditional Uses ◽  
Different Types ◽  
Promising Source

Background:: Adhatoda vasica (Nees.) of family Acanthaceae has been used in the Southeast tropical zone as it is efficacious against headache, colds, cough, whooping cough, fever, asthma, dyspnea, phthisis, jaundice, chronic bronchitis and diarrhea and exhibits commendable pharmacological activities. Objective: The aim of the review is to provide a systematic overview of pharmacological activities with toxicity and clinical assessment, phytochemistry of A. vasica along with its characterization, geographical observation, phenology, traditional uses as well as an organized representation of the findings. Method: The overall information of A. vasica were collected from various resources including books, review papers, research papers and reports which were obtained by an online search of worldwide-accepted scientific databases. ChemDraw software was used to draw the compounds’s structure. Results: Phytochemical review on A. vasica has led to the collection of 233 compounds of different types such as alkaloids, flavonoids, essential oils, terpenoids, fatty acids, phenols etc. It is a promising source of phytopharmaceutical potential agent that exhibits diverse pharmacological activities including antibacterial, antifungal, hepatoprotective, anti-ulcer, abortifacient, antiviral, anti-inflammatory, thrombolytic, hypoglycemic, anti-tubercular, antioxidant and antitussive activities. Conclusions: The sufficient number of studies on ethno-pharmacology, traditional uses and pharmacological activities of A. vasica are conducted. Furthermore, it is necessary to study the activity of chemical constituents for new drug design and discovery from natural products.

scholarly journals A REVIEW ON PHARMACOLOGICAL ACTIVITIES OF POLYALTHIA LONGIFOLIA L

2021 ◽  
pp. 172-177
Author(s):  
Dhiren k Vaghela ◽  
Dhruv Pandya ◽  
Hitesh Solanki
Keyword(s):  
Antimalarial Activity ◽  
Chemical Constituents ◽  
Antiulcer Activity ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Plant Parts ◽  
Ornamental Tree ◽  
Anti Oxidant ◽  
Polyalthia Longifolia

Polyalthia longifolia L. is an ornamental tree (mostly used as an avenue tree) which belongs to Annonaceae. As per the review of the research papers it also has so many important chemical constituents in its different parts. These chemicals are alkaloids, flavonoids, phenols, terpenoids and essensial oil etc that can be used for the preparation of different medicines for several diseases. In this review authors focused on the pharmacological properties and ethnomedicinal properties of the plant parts and their implementation in the pharmacological science. The plant part different extracts showed different types of pharmacological activities like Antibacterial activity, Antifungal activity, Antitumor (Anticancer activity), cytotoxic activity, Anti-oxidant activity, Anti-inflammatary activity, Antimalarial activity and Antiulcer activity. Even the plant also has so many traditional medicinal uses. So, its not just an ornamental tree but it can be good resourse for the secondary metabolites and considered as medicinally important plant.

scholarly journals Synsepalum Dulcificum: A Review

2020 ◽  
Vol 11 (3) ◽  
pp. 4208-4213
Author(s):  
Sadhana H M ◽  
Suresh Joghee ◽  
Hamsalakshmi
Keyword(s):  
Chemical Constituents ◽  
Sweet Taste ◽  
Literature Survey ◽  
The Internet ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Current Review ◽  
Anti Cancer ◽  
Reported Health ◽  
Transgenic Tomatoes

Synsepalum dulcificum also regarded as a miracle berry, belonging to the Sapotaceae family. It is cultivated for its mild fruits, which makes sour foods to give a sweet taste, the effect lasts for about 30 minutes. The plant is a shrub, containing red coloured fruits and localised to West Africa. They used this plant as their palm wine and also used this for certain other beverages to make it sweetened regionally. Because of its remarkable sweet potential used to make the sour foods taste sweet. Miraculin is the glycoprotein present in the plant responsible for the sweet taste. Some of the reported health benefits are anti-diabetic, effective food enhancer, taste disorder in cancer, alter the taste. The plant is known for its production of transgenic tomatoes. Ethnobotany uses of the plants includes in the treatment of male infertility, Asthma, Haemorrhoids, Anti-cancer etc. The aim of the present review was to brief the literature survey of the plant through the internet like PubMed and Google scholar for forming the platform to illustrate the ethnopharmacology of the plant, information about the traditional usage, important chemical constituents and selected pharmacological activities of the plant were gathered from available research papers to frame the review. The current review also highlights the phytochemical and pharmacological aspects of Synsepalum dulcificum which will have been helped in the researchers for the further qualitative research.

Withania Somnifera Linn as Herbal Source of Diverse Pharmacological Potential - A Comprehensive Review

2021 ◽  
Vol 12 (3) ◽  
pp. 1879-1885
Author(s):  
Kajal Panchal ◽  
Praveen K Dixit ◽  
Rajni Saini KM ◽  
Nagarajan K ◽  
Puspendra Kumar ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Blood Count ◽  
Withania Somnifera ◽  
Chemical Constituents ◽  
Review Article ◽  
Health Food ◽  
Pharmacological Activities ◽  
Comprehensive Review ◽  
Pharmacological Potential ◽  
Solanaceae Family

Ashwagandha, also known as Indian winter cherry, belonging to the Withania Somnifera Linn. (Solanaceae) family, (commonly available as Churna). Africa, the Mediterranean, and India are all home to this species. It is 30-50cm high and mainly found in the drier parts of India. Since it raises haemoglobin (red blood count) and hair melanin. Withania Somnifera is known as "Rasayana," which means "strong rejuvenator" in Ayurvedic jargon. In ethnomedicine, it is a well-known health food and herbal tonic that is used to treat cardiovascular diseases. It can be used as a single herb or as part of polyherbal or herbo-mineral formulations for humans. It is traditionally used to treat various  diseases such as inflammation, asthma, dyspepsia, hypertension, rheumatism, tumor, anxiety, hemopoietic, antimicrobial, depression, immunomodulation, antiulcer, hepatoprotective activities, Alzheimer’s, Parkinson’s disease, rejuvenating properties and syphilis. It has wide variety of chemical constituents such as withanoloides, flavonoid, saponins, glycosides, alkaloids, tannins, steroids have been studied. Despite the fact that previous review articles on this plant have been written, this review article is provided to bring together all of the most recent knowledge on its phytochemical and pharmacological activities.

scholarly journals Ethnobotanical and Pharmacological Importance of Western Himalayan Fir Abies pindrow (Royle ex D. Don) Royle: A Review

2019 ◽  
pp. 1-14
Author(s):  
Dwaipayan Sinha
Keyword(s):  
Bioactive Compounds ◽  
Indian Subcontinent ◽  
Chemical Constituents ◽  
Literature Survey ◽  
Extensive Literature ◽  
Bioactive Constituents ◽  
Pharmacological Activities ◽  
Traditional System ◽  
Bladder Diseases ◽  
Abies Pindrow

Aims: Abies pindrow (Royle ex D. Don) Royle., colloquially known as the Western Himalayan fir, is a conifer that grows along the Himalayan mountains from Afghanistan to Nepal. The plant is extensively used by locals for the treatments of various ailments. Thus based on the available reports about its importance in traditional system of medicine, an attempt has been made to review this species in context of its medicinal and pharmaceutical importance. Study Design: The review article has been designed based on literature survey. The article is grossly divided into four broad phases consisting of compiled information of Abies pindrow: (1) Ethnobotanical information (2) Chemical Constituents (3) Pharmacological activities (4) Discussion mainly highlighting the mode of action of the bioactive compounds in relation to its pharmacological activity. Methodology: Extensive literature search have been performed in the web using PubMed, PubMed Central, google scholar as search platform. Efforts have also been taken to compile information from research papers and review articles not more than 10 years old. Information from old literatures were preferably avoided unless found to be very relevant to the subject. Results: The literature survey revealed that the plant has been used to treat cough and cold, diabetes, cataract and bladder diseases. The plant is also considered to be carminative, astringent, antispasmodic, diuretic, tonic and anti-inflammatory. The plant is also rich in terpenes and terpene alcohols. Testing for antidiabetic, neuroprotective, anticataract and antixiolytic activities have been promising and the bioactive constituents and efforts are made to interpret the possible mechanism of action of bioactive compounds in bringing about the pharmacological activities. Conclusion: It is concluded that the plant can be explored and bioprospected for an affordable source of drug and nutraceutical for better management of health related issues of people of Indian subcontinent.

scholarly journals MESUA FERREA LINN. (NAGKESAR): A POTENT ANTIMICROBIAL PLANT SPECIES

2021 ◽  
pp. 6-13
Author(s):  
SHIFALI THAKUR ◽  
HEMLATA KAURAV ◽  
GITIKA CHAUDHARY
Keyword(s):  
Chemical Constituents ◽  
Vital Role ◽  
New Drugs ◽  
Renal Diseases ◽  
General Description ◽  
Bioactive Constituents ◽  
Pharmacological Activities ◽  
Herbal Plants ◽  
Medicinal Properties ◽  
Therapeutic Activities

Many plants have not been investigated thoroughly, which are used traditionally as a medicine to cure various diseases. Herbal plants play a vital role in the development of new drugs which can be used for various therapeutic indications. Mesua ferrea linn., commonly known as 'Nagchampa' or 'Nagkesar', is one such herbal plant having many potential therapeutic activities. It is used in diseases like rheumatism, asthma, inflammation, fever, dyspepsia, renal diseases, dysentery, bleeding piles, a bacterial and fungal infection. This plant possesses many bioactive chemical constituents like coumarins, xanthones, pyranoxanthones, flavonoids, terpenoids and steroids which can be easily isolated. It can act as precursors on many ailments. These bioactive constituents have many pharmacological activities such as anticancer, antimicrobial, antifungal, anti-inflammatory, anti-arthritis, analgesic, diuretic, anti-hemorrhoid, antiulcer and many more. Almost every part of the plant is reported to have beneficial medicinal properties. But further studies are still needed to explore the pharmacological activities of Mesua ferrea linn. plant so as to gain benefit for the treatment of various diseases. This review highlights the general description, phytochemical profiling, traditional uses and proven pharmacological attributes of Mesua ferrea linn. plant.

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