Occupational diseases of builders and factors affecting their occurrence and development

Author(s):  
D. V. Semenov ◽  
A. A. Tkachenko

The article deals with individual professional diseases of builders and the factors that influence their occurrence and development. The author believes that a wide range of industrial activities of representatives of the construction professions and the impact of the environment plays a vital role in the development and progression of most occupational diseases. However, the harmful effects of these diseases on the body are greatly underestimated, which reduces the effectiveness of preventive measures and complicates treatment. It is also impossible to ignore the occupational diseases of drivers of construction vehicles. The most common of them are diseases associated with the development of cardiovascular pathology, neuropsychiatric disorders, gastrointestinal disorders, diseases associated with problems with the musculoskeletal system, disorders caused by a sedentary lifestyle, as well as allergic and oncological diseases. In addition, drivers are affected by harmful sanitary and hygienic factors: noise, vibration, high temperature, harmful impurities in the bus cabin, nervous tension. Taking into account all the above factors, it is necessary to carry out appropriate prevention of occupational diseases of representatives of construction specialties by conducting educational work and conducting regular medical examinations.

Author(s):  
Igor B. Maksimov ◽  
Marina A. Fesenko ◽  
Vladimir I. Sinopalnikov ◽  
Aleksey N. Diashev

Introduction. In the modern world, the introduction of digital technologies in healthcare is one of the priorities of development, which opens up a wide range of opportunities from screening and monitoring to various health disorders. In 2020 we completed the work to evaluate the applied capabilities of contactless videoplethysmography based on the telemetric control system developed by us and patented using the DISITA software and hardware complex during pre-trip post-trip medical examinations in 19 drivers of passenger vehicles. The study aims to explore the possibilities of the data of variational heart rate monitoring using reflected video plethysmography in assessing drivers' performance in their work. We have identified the most sensitive and significant heart rate variability indicators that reflect the professional load's impact. Materials and methods. We carried out during the usual pre-trip examination, video plethysmography of the skin of the face of the subjects in parallel in conditions of both natural daylight and typical artificial lighting of medical and diagnostic rooms, at a distance of the recording WEB camera of the DISITA software and hardware complex from the face of the subject within 40-70 cm. Researchers examined the methodological recommendations developed by the Izmerov Research Institute of Occupational Health team and RT-Medicine JSC. Results. We use videoplethysmography to evaluate variational heart rate monitoring as a method for assessing functional states during mass pre-trip (pre-shift) and post-trip (post-shift) medical examinations. In this case, the heart rate estimated by palpation was identical to the heart rate obtained by videoplethysmography. The most sensitive parameters characterizing the impact of professional load on drivers were changes in the indicators of variational heart rate monitoring: SDNN, RMSSD, CV, TR, HF, LF, and the waves of vasomotion regulation. Conclusions. Videoplethysmography with an assessment of the data of variational heart rate monitoring can be used to predict the functional state (stability of the body) of drivers in the course of their professional activities.


2021 ◽  
Vol 22 (13) ◽  
pp. 6845
Author(s):  
Rebecca L. Pratt

The buzz about hyaluronan (HA) is real. Whether found in face cream to increase water volume loss and viscoelasticity or injected into the knee to restore the properties of synovial fluid, the impact of HA can be recognized in many disciplines from dermatology to orthopedics. HA is the most abundant polysaccharide of the extracellular matrix of connective tissues. HA can impact cell behavior in specific ways by binding cellular HA receptors, which can influence signals that facilitate cell survival, proliferation, adhesion, as well as migration. Characteristics of HA, such as its abundance in a variety of tissues and its responsiveness to chemical, mechanical and hormonal modifications, has made HA an attractive molecule for a wide range of applications. Despite being discovered over 80 years ago, its properties within the world of fascia have only recently received attention. Our fascial system penetrates and envelopes all organs, muscles, bones and nerve fibers, providing the body with a functional structure and an environment that enables all bodily systems to operate in an integrated manner. Recognized interactions between cells and their HA-rich extracellular microenvironment support the importance of studying the relationship between HA and the body’s fascial system. From fasciacytes to chronic pain, this review aims to highlight the connections between HA and fascial health.


2018 ◽  
Vol 860 ◽  
pp. 739-766 ◽  
Author(s):  
Rémi Bourguet

The flow-induced vibrations of an elastically mounted circular cylinder, free to oscillate in an arbitrary direction and forced to rotate about its axis, are examined via two- and three-dimensional simulations, at a Reynolds number equal to 100, based on the body diameter and inflow velocity. The behaviour of the flow–structure system is investigated over the entire range of vibration directions, defined by the angle $\unicode[STIX]{x1D703}$ between the direction of the current and the direction of motion, a wide range of values of the reduced velocity $U^{\star }$ (inverse of the oscillator natural frequency) and three values of the rotation rate (ratio between the cylinder surface and inflow velocities), $\unicode[STIX]{x1D6FC}\in \{0,1,3\}$, in order to cover the reference non-rotating cylinder case, as well as typical slow and fast rotation cases. The oscillations of the non-rotating cylinder ($\unicode[STIX]{x1D6FC}=0$) develop under wake-body synchronization or lock-in, and their amplitude exhibits a bell-shaped evolution, typical of vortex-induced vibrations (VIV), as a function of $U^{\star }$. When $\unicode[STIX]{x1D703}$ is increased from $0^{\circ }$ to $90^{\circ }$ (or decreased from $180^{\circ }$ to $90^{\circ }$), the bell-shaped curve tends to monotonically increase in width and magnitude. For all angles, the flow past the non-rotating body is two-dimensional with formation of two counter-rotating spanwise vortices per cycle. The behaviour of the system remains globally the same for $\unicode[STIX]{x1D6FC}=1$. The principal effects of the slow rotation are a slight amplification of the VIV-like responses and widening of the vibration windows, as well as a limited asymmetry of the responses and forces about the symmetrical configuration $\unicode[STIX]{x1D703}=90^{\circ }$. The impact of the fast rotation ($\unicode[STIX]{x1D6FC}=3$) is more pronounced: VIV-like responses persist over a range of $\unicode[STIX]{x1D703}$ but, outside this range, the system is found to undergo a transition towards galloping-like oscillations characterised by amplitudes growing unboundedly with $U^{\star }$. A quasi-steady modelling of fluid forcing predicts the emergence of galloping-like responses as $\unicode[STIX]{x1D703}$ is varied, which suggests that they could be mainly driven by the mean flow. It, however, appears that flow unsteadiness and body motion remain synchronised in this vibration regime where a variety of multi-vortex wake patterns are uncovered. The interaction with flow dynamics results in deviations from the quasi-steady prediction. The successive steps in the evolution of the vibration amplitude versus $U^{\star }$, linked to wake pattern switch, are not captured by the quasi-steady approach. The flow past the rapidly-rotating, vibrating cylinder becomes three-dimensional over an interval of $\unicode[STIX]{x1D703}$ including the in-line oscillation configuration, with only a minor effect on the system behaviour.


2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Mirko Andreja Borisov

Climate change conditions a wide range of impacts such as the impact on weather, but also on ecosystems and biodiversity, agriculture and forestry, human health, hydrological regime and energy. In addition to global warming, local factors affecting climate change are being considered. Presentation and analysis of the situation was carried out using geoinformation technologies (radar recording, remote detection, digital terrain modeling, cartographic visualization and geostatistics). This paper describes methods and use of statistical indicators such as LST, NDVI and linear correlations from which it can be concluded that accelerated construction and global warming had an impact on climate change in period from 1987 to 2018 in the area of Vojvodina – Republic of Serbia. Also, using the global SRTM DEM, it is shown how the temperature behaves based on altitude change. Conclusions and possible consequences in nature and society were derived.


2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Hongbo Guan ◽  
Yanyan Guo ◽  
Liangliang Zhu ◽  
Yisheng Jiao ◽  
Xiaomei Liu

An adverse intrauterine environment impairs the development of pancreatic islets in the fetus and leads to insufficient β cell mass and β cell dysfunction. We previously reported that Pex14, a peroxin protein involved in the biogenesis and degradation of peroxisomes, is markedly reduced in the pancreas of an intrauterine growth restriction fetus and last into adulthood. Peroxisomes function in a wide range of metabolic processes including fatty acid oxidization, ROS detoxification, and anti-inflammatory responses. To elucidate the impact of downregulation of the Pex14 gene on β cell, Pex14 was knocked down by siRNA in INS-1 cells. Pex14 knockdown disturbed peroxisomal biogenesis and dysregulated fatty acid metabolism and lipid storage capability, thereby increased ROS level and blunted insulin secretion. Moreover, Pex14 knockdown upregulated inflammation factors and regulators of endoplasmic reticulum stress. The lipotoxicity of fatty acid (including palmitic acid and linoleic acid) in β cells was exacerbated by knockdown of Pex14, as indicated by H2O2 accumulation and increased programmed cell death. The present results demonstrate the vital role of Pex14 in maintaining normal peroxisome function and β cell viability and highlight the importance of a functional peroxisomal metabolism for the detoxification of excess FAs in β cells.


Author(s):  
Д.А. Еникеев ◽  
Л.Т. Идрисова ◽  
О.А. Еникеев ◽  
К.О. Кузнецов ◽  
Д.Р. Ахмадеева ◽  
...  

В статье представлены актуальные данные экспериментальных и клинических исследований по изучению влияния различных средств доставки никотина в организм курильщика. Проведён сравнительный анализ воздействия табачных сигарет, электронных средств доставки никотина и системы нагревания табака IQOS на показатели здоровья и развития организма человека, а также лабораторных животных. Показано, что, несмотря на громкие заявления производителей альтернативных средств доставки никотина о полной безвредности их устройств, результаты экспериментальных исследований обнаруживают в них не только известные канцерогены, но и новые потенциально опасные вещества, которые не содержатся в обычных сигаретах, и влияние которых на организм достаточно не изучено. На данный момент имеются все основания полагать, что употребление электронных сигарет и IQOS может приводить к заболеваниям нервной, кроветворной, иммунной, дыхательной систем, а также к развитию онкологических заболеваний. The article presents current results of experimental and clinical studies focusing on effects of various nicotine delivery systems. The authors conducted a comparative analysis of the impact of tobacco cigarettes, electronic nicotine delivery devices, and IQOS tobacco heating systems on the health and development of humans and laboratory animals. The review of recent literature has shown that, despite ambitious statements of the manufacturers about complete safety of their devices, experiments have demonstrated that they release not only well-known carcinogens but also new, potentially hazardous substances. These substances are not contained in ordinary cigarettes, and their effects on the body has not been sufficiently studied. Presently, it seems very likely that the use of electronic cigarettes and IQOS can lead to diseases of the nervous, hematopoietic, immune, and respiratory systems as well as to oncological diseases.


2021 ◽  
Vol 91 (5) ◽  
pp. 507-519
Author(s):  
Małgorzata Bronikowska ◽  
Małgorzata Pisarska-Jamroży ◽  
A.J. (Tom) van Loon

ABSTRACT Dropstones in lacustrine and marine sediments show a wide range of sizes: from less than a millimeter to many meters. Their size and shape determine the velocity and the acceleration when they settle through the water column, and this, in turn, determines in principle the imprint that they make in the bottom sediment. Although these parameters are crucial for dropstone deposition, the unknown material (sediment) properties (like strength, porosity, pore-water content, viscosity, etc.) of the bottom sediment play a just as important role in this process as the water depth, which can physically be understood as the length of the pathway traveled vertically through a dense medium before the impact. Reconstruction of the principal environmental conditions at the time of dropstone fall and deposition consequently requires considering the variety of factors affecting the final imprint depth of a dropstone, the combination of several numerical methods. Here, we show the results of numerical modeling of dropstones with different sizes that settle through water columns with different depths. Our results show how environmental factors control the deformation structures formed at the sedimentary surface during the impact of a dropstone, and how deep the imprint caused by the settling dropstone will be.


2010 ◽  
Vol 69 (4) ◽  
pp. 511-517 ◽  
Author(s):  
Robert F. Grimble

The objective of the present review is to provide an overview of the metabolic effects of pro-inflammatory cytokine production during infection and injury; to highlight the disadvantages of pro-inflammatory cytokine production and inflammatory stress on morbidity and mortality of patients; to identify the influence of genetics and adiposity on inflammatory stress in patients and to indicate how nutrients may modulate the inflammatory response in patients. Recent research has shown clearly that adipose tissue actively secretes a wide range of pro- and anti-inflammatory cytokines. Paradoxically, although inflammation is an essential part of the response of the body to infection, surgery and trauma, it can adversely affect patient outcome. The metabolic effects of inflammation are mediated by pro-inflammatory cytokines. Metabolic effects include insulin insensitivity, hyperlipidaemia, muscle protein loss and oxidant stress. These effects, as well as being present during infective disease, are also present in diseases with a covert inflammatory basis. These latter diseases include obesity and type 2 diabetes mellitus. Inflammatory stress also increases during aging. The level of cytokine production, within individuals, is influenced by single nucleotide polymorphisms (SNP) in cytokine genes. The combination of SNP controls the relative level of inflammatory stress in both overt and covert inflammatory diseases. The impact of cytokine genotype on the intensity of inflammatory stress derived from an obese state is unknown. While studies remain to be done in the latter context, evidence shows that these genomic characteristics influence morbidity and mortality in infectious disease and diseases with an underlying inflammatory basis and thereby influence the cost of in-patient obesity. Antioxidants andn-3 PUFA alter the intensity of the inflammatory process. Recent studies show that genotypic factors influence the effectiveness of immunonutrients. A better understanding of this aspect of nutrient–gene interactions and of the genomic factors that influence the intensity of inflammation during disease will help in the more effective targeting of nutritional therapy.


1999 ◽  
Vol 122 (4) ◽  
pp. 611-616 ◽  
Author(s):  
Daniel B. Olsen ◽  
Charles E. Mitchell

Current research shows that the only hazardous air pollutant of significance emitted from large bore natural gas engines is formaldehyde CH2O. A literature review on formaldehyde formation is presented focusing on the interpretation of published test data and its applicability to large bore natural gas engines. The relationship of formaldehyde emissions to that of other pollutants is described. Formaldehyde is seen to have a strong correlation to total hydrocarbon (THC) level in the exhaust. It is observed that the ratio of formaldehyde to THC concentration is roughly 1.0–2.5 percent for a very wide range of large bore engines and operating conditions. The impact of engine operating parameters, load, rpm, spark timing, and equivalence ratio, on formaldehyde emissions is also evaluated. [S0742-4795(00)01004-8]


Energies ◽  
2022 ◽  
Vol 15 (1) ◽  
pp. 354
Author(s):  
Ludovica Maria Campagna ◽  
Francesco Fiorito

The body of literature on climate change impacts on building energy consumption is rising, driven by the urgency to implement adaptation measures. Nevertheless, the multitude of prediction methodologies, future scenarios, as well as climate zones investigated, results in a wide range of expected changes. For these reasons, the present review aims to map climate change impacts on building energy consumption from a quantitative perspective and to identify potential relationships between energy variation and a series of variables that could affect them, including heating and cooling degree-days (HDDs and CDDs), reference period, future time slices and IPCC emission scenarios, by means of statistical techniques. In addition, an overview of the main characteristics of the studies related to locations investigated, building types and methodological approaches are given. To sum up, global warming leads to: (i) decrease in heating consumptions; (ii) increase in cooling consumption; (iii) growth in total consumptions, with notable differences between climate zones. No strong correlation between the parameters was found, although a moderate linear correlation was identified between heating variation and HDDs, and total variation and HDDs. The great variability of the collected data demonstrates the importance of increasing specific impact studies, required to identify appropriate adaptation strategies.


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