scholarly journals Sports Psychiatry: Exercise and postpartum depression

2020 ◽  
Keyword(s):  
Depressive Symptoms ◽  
Postpartum Depression ◽  
Life Stress ◽  
Depressive Disorders ◽  
Treatment Strategies ◽  
Depression Scale ◽  
New Mothers ◽  
Depressive Feelings ◽  
Baby Blues ◽  
Mood Lability

Postpartum depression (PPD) is a common psychiatric disorder in the peripartum period affecting approximately 8% of European women without prior psychiatric history [1] and even more with pre-existing depressive disorders. Up to 70% of new mothers develop mild depressive symptoms called “baby-blues” which include weepiness, sadness and mood lability. Those symptoms usually peak between 2 and 5 days post-delivery and abate spontaneously within days up to 2 weeks [2]. In contrast to “baby blues” postpartum depression can have a serious impact on functioning and even lead to suicidality rendering it highly important to detect the disorder as early as possible. The Edinburgh Postnatal Depression Scale (EPDS) [3] is widely used to screen for postpartum depression and should be applied to all new mothers who develop depressive symptoms such as loss of interest, hopelessness and depressive feelings. Several risk factors for postpartum depression have been identified: Prenatal depression poses the highest risk, followed by low self-esteem, childcare stress, prenatal anxiety, life stress and lack of social support [4]. Postpartum depression is a treatable condition, however, it has to be distinguished from bipolar disorder and postpartum psychosis, which require different treatment strategies [2].

Post-partum depression risk factors in pregnant women

2016 ◽  
Vol 33 (S1) ◽  
pp. s279-s280
Author(s):  
A. Ugarte ◽  
P. López ◽  
C. Serrulla ◽  
M.T. Zabalza ◽  
J.G. Torregaray ◽  
...  
Keyword(s):  
Risk Factors ◽  
Depressive Symptoms ◽  
Postpartum Depression ◽  
Depressive Disorders ◽  
Post Partum ◽  
Depression Scale ◽  
Personal History ◽  
Assisted Reproductive Technique ◽  
History Of ◽  
Competing Interest

IntroductionPostpartum depression has a prevalence of 15% and has consequences for mother and baby (delayed physical, social and cognitive development). It's essential to prevent the illness with an early identification of Risk Factors (RF).MethodsFive hundred and seventy-two women in 3rd trimester of pregnancy were evaluated and selected those with ≥ 1 RF (n = 290). We re-evaluated in the postpartum with Edinburgh Depression Scale and selected those with subsyndromal depressive symptoms (≥ 7.5) (n = 57). Clinical, demographic and functional data were collected.ResultsA total of 50.7% had RF. A percentage of 48.6 had family history of mental illness (MI), 34.1%had personal history of (MI) and 34.1% had some pregnancy associated illness. Twenty percent had needed some assisted reproductive technique, 14.1% had little family support and 15.2% had little couple support, 3.8% showed anxiety-depressive disorders during pregnancy, 19.7% had depressive symptoms after delivery. The mean age was 33.67. No significant differences between patients with and without RF (T-1858, P 0.064). Among women with RF, 59.6% were married, 35.1% single and 3.0% had other situation. 89.5% live with their own family, 8.8% with their family of origin, 1.8% alone. 50.8% had university studies.ConclusionsAssessing RF during pregnancy can help these women, since we see that the 19.7% will have serious risk of developing postpartum depression. The RF to take more into account are not those related to social-academic development, neither the presence of anxiety-depressive symptoms during pregnancy, but the family or personal history of (MI) and the presence of a pregnancy associated illness. Early detection and treatment may prevent the development of this disease improving the quality of life of mother and babies’ development.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals The Effectiveness of Telehealth Interventions on Women with Postpartum Depression: A Systematic Review and Meta-Analysis (Preprint)

2021 ◽  
Author(s):  
Liuhong Zhao ◽  
Jingfen Chen ◽  
Yan Liao ◽  
Liuying Lan ◽  
Ni Deng ◽  
...  
Keyword(s):  
Social Support ◽  
Systematic Review ◽  
Depressive Symptoms ◽  
Postpartum Depression ◽  
Large Scale ◽  
Meta Analysis ◽  
Treatment Strategies ◽  
Depression Scale ◽  
Cochrane Library ◽  
Control Group

BACKGROUND Background: Postpartum depression is a highly prevalent mental health problem with potential for serious adverse consequences. Telehealth interventions can increase the accessibility to treatments for postpartum depression and their effectiveness has been assessed by clinical trials. However, no comprehensive synthesis of findings by systematic review has been conducted. OBJECTIVE Objective: To evaluate the effectiveness of telehealth interventions on women with postpartum depression in terms of reducing depressive symptoms, anxiety and loneliness, and improving social support. METHODS Methods: PubMed, The Cochrane Library, CINAHL, PsycINFO, CNKI, and Wan Fang database were electronically searched to identify studies with randomized controlled trials (RCTs) on the effectiveness of telehealth interventions on women with postpartum depression from inception to February 28, 2021. Data extraction and quality assessment were performed by two researchers independently. The quality of included studies was assessed using the Cochrane risk-of-bias tool, and meta-analysis was performed using RevMan 5.4 software. RESULTS Results: A total of 1,958 women with postpartum depression from nine RCTs were included. The meta-analysis showed that the scores of Edinburgh Postnatal Depression Scale (EPDS) [MD=-2.99, 95%CI (-4.52, -1.46), P<.001] and anxiety [SMD=-0.39, 95%CI (-0.67, -0.12), P=.005] were significantly lower in the telehealth group compared with the control group. No significant differences were observed for social support and loneliness. Significant subgroup differences were found for depressive symptoms according to the severity of postpartum depression, telehealth technology used, specific therapy, and follow up time periods (P<.001). CONCLUSIONS Conclusions: Telehealth interventions are effective in reducing depression and anxiety in women with postpartum depression. However, large scale RCTs targeting specific therapies in women are needed to help tailor treatment strategies to individuals. CLINICALTRIAL PROSPERO CRD42021258541; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=258541

scholarly journals Genome-wide gene expression changes in postpartum depression point towards an altered immune landscape

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Divya Mehta ◽  
Karen Grewen ◽  
Brenda Pearson ◽  
Shivangi Wani ◽  
Leanne Wallace ◽  
...  
Keyword(s):  
Gene Expression ◽  
Depressive Symptoms ◽  
Postpartum Depression ◽  
Expression Profiles ◽  
Depression Scale ◽  
Well Being ◽  
Health Concern ◽  
Genome Wide ◽  
A Genome ◽  
Genome Wide Gene Expression

AbstractMaternal postpartum depression (PPD) is a significant public health concern due to the severe negative impact on maternal and child health and well-being. In this study, we aimed to identify genes associated with PPD. To do this, we investigated genome-wide gene expression profiles of pregnant women during their third trimester of pregnancy and tested the association of gene expression with perinatal depressive symptoms. A total of 137 women from a cohort from the University of North Carolina, USA were assessed. The main phenotypes analysed were Edinburgh Postnatal Depression Scale (EPDS) scores at 2 months postpartum and PPD (binary yes/no) based on an EPDS cutoff of 10. Illumina NextSeq500/550 transcriptomic sequencing from whole blood was analysed using the edgeR package. We identified 71 genes significantly associated with postpartum depression scores at 2 months, after correction for multiple testing at 5% FDR. These included several interesting candidates including TNFRSF17, previously reported to be significantly upregulated in women with PPD and MMP8, a matrix metalloproteinase gene, associated with depression in a genome-wide association study. Functional annotation of differentially expressed genes revealed an enrichment of immune response-related biological processes. Additional analysis of genes associated with changes in depressive symptoms from recruitment to 2 months postpartum identified 66 genes significant at an FDR of 5%. Of these genes, 33 genes were also associated with depressive symptoms at 2 months postpartum. Comparing the results with previous studies, we observed that 15.4% of genes associated with PPD in this study overlapped with 700 core maternal genes that showed significant gene expression changes across multiple brain regions (P = 7.9e-05) and 29–53% of the genes were also associated with estradiol changes in a pharmacological model of depression (P values range = 1.2e-4–2.1e-14). In conclusion, we identified novel genes and validated genes previously associated with oestrogen sensitivity in PPD. These results point towards the role of an altered immune transcriptomic landscape as a vulnerability factor for PPD.

scholarly journals Pregnancy, perinatal and postpartum complications as determinants of postpartum depression: the Rhea mother–child cohort in Crete, Greece

2016 ◽  
Vol 27 (3) ◽  
pp. 244-255 ◽  
Author(s):  
K. Koutra ◽  
M. Vassilaki ◽  
V. Georgiou ◽  
A. Koutis ◽  
P. Bitsios ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Postpartum Depression ◽  
Postpartum Period ◽  
Depression Scale ◽  
Effective Prevention ◽  
Maternal Mood ◽  
Early Postpartum Period ◽  
Early Postpartum ◽  
Wide Range ◽  
Clinical Records

Aims.Few epidemiological studies evaluated associations between perinatal complications and maternal mood at the early postpartum period and the findings are inconsistent. We aimed at investigating a wide range of complications during pregnancy, at delivery, and at the early postpartum period as determinants of postpartum depression (PPD) at 8 weeks postpartum.Methods.A total of 1037 women who enrolled in the Rhea mother–child cohort in Crete, Greece participated in the present study. Information on pregnancy, perinatal and postpartum complications was obtained from clinical records or by questionnaires. Postpartum depressive symptoms were assessed at 8 weeks postpartum using the Edinburgh Postnatal Depression Scale (EPDS). Multivariable linear and logistic regression models were fit to estimate the association between pregnancy, perinatal and postpartum complications and maternal depressive symptoms, adjusting also for potential confounders.Results.The prevalence of women with probable depression (EPDS score ≥ 13) was 13.6% at 8 weeks postpartum. Gestational hypertension and/or preeclampsia (β coefficient 1.86, 95% CI: 0.32, 3.41) and breastfeeding difficulties (β coefficient 0.77, 95% CI: 0.02, 1.53) were significantly associated with higher PPD symptoms. Sleep patterns during pregnancy, such as sleep deprivation (OR = 3.57, 95% CI: 1.91, 6.67) and snoring (OR = 1.81, 95% CI: 1.11, 2.93), and breastfeeding duration less than 2 months (OR = 1.77, 95% CI: 1.19, 2.64) were significantly associated with increase in the odds for PPD. Some other complications, such as unplanned pregnancy and hospitalisation during pregnancy were also associated with EPDS score, but these associations were explained by socio-demographic characteristics of the mother.Conclusions.We found that several pregnancy, perinatal and postpartum complications may have an adverse effect on maternal mood at the early postpartum period. These findings have considerable implications for developing effective prevention and early psychoeducational intervention strategies for women at risk of developing PPD.

Symptom Frequencies and Intensities in Hospitalized Patients With Advanced Cancer Having Depressive Disorder

2016 ◽  
Vol 34 (5) ◽  
pp. 456-460 ◽  
Author(s):  
Yong Liu ◽  
Fei Liu ◽  
Yang Yu ◽  
Qing Li ◽  
Xin Jin ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Advanced Cancer ◽  
Depressive Disorders ◽  
Depression Scale ◽  
Rank Correlation ◽  
Symptom Assessment ◽  
Hospitalized Patients ◽  
Assessment System ◽  
Wilcoxon Rank Sum Test

Aim: To explore the frequencies and intensities of depressive symptoms associated with hospitalized patients with advanced cancer. Methods: A total of 196 hospitalized patients with advanced cancer were surveyed with the Edmonton Symptom Assessment System and Self-Rating Depression Scale (SDS). The χ2 test and Wilcoxon rank-sum test were used to compare the frequency and intensity of symptoms between patients with and without depressive disorders. Spearman rank correlation was used to test the correlation between depression and symptoms. Results: Of the 196 enrolled patients, 115 (59%) were males. The median age of the patients was 58 (19-80) years. Seventy-six (39%) patients were diagnosed with depression (SDS ≥ 53). Patients with depressive disorders exhibited pain, drowsiness, and nausea along with a higher frequency and intensity of poor self-perception, appetite loss, anxiety, dyspnea, and fatigue. Depressive symptoms were positively correlated with the symptoms. Conclusion: Depressive disorders are very common and severe in hospitalized patients with advanced cancer. Identifying the frequencies and intensities of the symptoms enables early intervention to improve patients’ quality of life.

scholarly journals The Relationship Between Images Posted by New Mothers on WeChat Moments and Postpartum Depression: Cohort Study (Preprint)

2020 ◽  
Author(s):  
Weina Zhang ◽  
Lu Liu ◽  
Qijin Cheng ◽  
Yan Chen ◽  
Dong Xu ◽  
...  
Keyword(s):  
Social Media ◽  
Postpartum Depression ◽  
Facial Expressions ◽  
Postpartum Period ◽  
Positive Emotions ◽  
Depression Scale ◽  
Image Features ◽  
New Mothers ◽  
Media Platform ◽  
Clinical Trials Registry

BACKGROUND As social media posts reflect users’ emotions, WeChat Moments, the most popular social media platform in China, may offer a glimpse into postpartum depression in the population. OBJECTIVE This study aimed to investigate the features of the images that mothers posted on WeChat Moments after childbirth and to explore the correlation between these features and the mothers' risk of postpartum depression. METHODS We collected the data of 419 mothers after delivery, including their demographics, factors associated with postpartum depression, and images posted on WeChat Moments. Postpartum depression was measured using the Edinburgh Postnatal Depression Scale. Descriptive analyses were performed to assess the following: content of the images, presence of people, the people’s facial expressions, and whether or not memes were posted on WeChat Moments. Logistic regression analyses were used to identify the image features associated with postpartum depression. RESULTS Compared with pictures of other people, we found that pictures of their children comprised the majority (3909/6887, 56.8%) of the pictures posted by the mothers on WeChat Moments. Among the posts showing facial expressions or memes, more positive than negative emotions were expressed. Women who posted selfies during the postpartum period were more likely to have postpartum depression (<i>P</i>=.003; odds ratio 2.27, 95% CI 1.33-3.87). CONCLUSIONS The vast majority of mothers posted images conveying positive emotions during the postpartum period, but these images may have masked their depression. New mothers who have posted selfies may be at a higher risk of postpartum depression. CLINICALTRIAL International Clinical Trials Registry Platform ChiCTR-ROC-16009255; http://www.chictr.org.cn/showproj.aspx?proj=15699

scholarly journals Postpartum depression and the scarcity of generalizable evidence: A mini-review of existing literature and the way forward

2021 ◽  
Vol 11 (2) ◽  
pp. 81-84
Author(s):  
Fidelis E Uwumiro ◽  
Victory O Okpujie ◽  
Kingsley O Anokwuru
Keyword(s):  
Postpartum Depression ◽  
Mental Health Professionals ◽  
Depressive Disorders ◽  
Early Recognition ◽  
Depression Scale ◽  
Diagnostic Tools ◽  
Diagnostic And Statistical Manual ◽  
The Bible ◽  
Patient Health ◽  
Distinct Disease

The first known reference to Postpartum Depression (PPD), was Hippocrates’ 4th century hypothesis that drainage of lochia, if suppressed, could flow to the brain resulting in agitation, delirium, and episodes of mania. This hypothesis became dogma and lasted over a millennium. Over the years, knowledge of PPD has evolved but researchers still struggle to establish it as a distinct disease entity. It was initially recognized as Major Depressive Disorder (MDD) with postpartum onset in the 1994 revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), the “bible” of diagnostic criteria for mental health professionals and researchers. It is currently recognized as MDD with peripartum onset (DSM-V) and researchers have admitted that persuasive evidence to indicate that postpartum depression is distinct from other existing depressive disorders, has not been found. Several diagnostic tools such as the Edinburg Postpartum Depression Scale (EDPS), the Beck Depression Inventory (BDI-II), Patient Health Questionnaire (PHQ-9), and the Postpartum Depression Screening Scale (PDSS) are available for use but none of these is universally accepted. With much of the published literature plagued with bias and structural inconsistencies, the credibility of the evidence has been greatly diminished. The difficulty with disease designation, the absence of a universally accepted tool for diagnosis and the scarcity of generalizable evidence on the subject has impaired the early recognition and effective management of PPD. It is therefore expedient, to critically appraise some of the available literature and proffer solutions to navigating this conundrum.

scholarly journals Cross-sectional Association Between Vitamin B12 Status and Probable Postpartum Depression in Indian Women

2020 ◽  
Author(s):  
Pooja Dhiman ◽  
Raji R Pillai ◽  
Anand B Wilson ◽  
Nancy Premkumar ◽  
Balaji Bharadwaj ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Postpartum Depression ◽  
Vitamin B12 ◽  
Depression Scale ◽  
Biologically Active ◽  
Total Vitamin ◽  
Active Molecule ◽  
Cross Sectional ◽  
Indian Women ◽  
Probable Depression

Abstract BackgroundVitamin B12 is an essential micronutrient for neurological function, as it leads to the regeneration of methionine from homocysteine, which is precursor of biologically active molecule SAM. Pregnancy is a state of increased demand and delayed postpartum repletion of nutrients may predispose women to depression. MethodsWomen attending postpartum clinic at 6 weeks post-delivery were screened for the presence of depressive symptoms using Edinburg postpartum depression scale (EPDS). Based on a cut-off of 10, two groups were taken- women with probable depression with EPDS score>10 (n=217) and women without probable depression with EPDS score<10(n=217). Plasma total vitamin B12, holotranscobalamin, homocysteine, MMA, 5-methyl THF, SAM and serotonin levels were estimated using commercially available ELISA kits. Combined B12(cB12) score was calculated and analysis of resulting data was done using SPSS ver20.0. ResultsTotal vitamin B12 was significantly lower (p=0.001) and MMA (p=0.002) and 5-methyl THF(p<0.001) levels were higher in women with probable depression than women without probable depression. Combined B12 index was also lower in women with probable PPD (p=0.001). Women in the lowest vitamin B12 quartile had 4.53 times higher likelihood of probable postpartum depression (p < 0.001). Decreasing vitamin B12 (OR = 0.394; 95% CI: 0.189-0.822) and cB12 (OR=0.293; 95% CI:0182-0.470) and increasing MMA (OR = 2.14; 95% CI: 1.63-2.83) and 5-methyl THF levels (OR = 3.29; 95% CI: 1.59-6.83) were significantly associated with the risk of PPD.ConclusionLow vitamin B12 may contribute to depressive symptoms in vulnerable postpartum period.

scholarly journals Trends of Perinatal Stress, Anxiety, and Depression and Their Prediction on Postpartum Depression

2021 ◽  
Vol 18 (17) ◽  
pp. 9307
Author(s):  
Ching-Yu Cheng ◽  
Yu-Hua Chou ◽  
Chia-Hao Chang ◽  
Shwu-Ru Liou
Keyword(s):  
Depressive Symptoms ◽  
Postpartum Depression ◽  
Depression Scale ◽  
Late Pregnancy ◽  
Estimating Equation ◽  
Epidemiologic Studies ◽  
Anxiety And Depression ◽  
Pregnancy And Postpartum ◽  
Postpartum Stress ◽  
Spearman’S Correlation

Perinatal stress, anxiety, and depression impacts not only women but also their child(ren). The purpose of this longitudinal study is to explore trends of stress, anxiety, and depressive symptoms from pregnancy to postpartum and understand predictions of stress and anxiety on postpartum depression. One-hundred-fifty-six women at 23–28 weeks gestation (T1), 147 at 32–36 weeks gestation (T2), 129 at over 36 weeks gestation (T3), and 83 at postpartum (T4) completed study surveys. The Perceived Stress Scale, Center for Epidemiologic Studies Depression scale, and State-Trait Anxiety Inventory were used to measure stress, depressive symptoms, and anxiety. Descriptive statistics, Pearson and Spearman’s correlation, and Generalized Estimating Equation were applied to analyze the data. Results showed that levels of anxiety and depressive symptoms increased from 24 weeks gestation to postpartum, whereas stress levels decreased during pregnancy but increased in postpartum. Over half of women experienced anxiety symptoms, especially during late pregnancy and postpartum. Stress, anxiety, and depressive symptoms were inter-correlated. Notably, women at late pregnancy and postpartum were prone to stress, anxiety, and depression. Prenatal anxiety could predict postpartum depressive symptoms. Active assessment and management of stress, anxiety, and depression is needed and should begin from early pregnancy and continue until postpartum.

GEJALA DEPRESI POSTPARTUM MEMPENGARUHI KEBERHASILAN ASI EKSKLUSIF : Sistematik Literatur Riview

2020 ◽  
pp. 27-34
Author(s):  
Nova Arami ◽  
Surahma Asti Mulasari ◽  
Ummu Hani EN
Keyword(s):  
Depressive Symptoms ◽  
Breast Milk ◽  
Postpartum Depression ◽  
Low Income ◽  
Critical Appraisal ◽  
Previous History ◽  
Synthesis Method ◽  
Depression Scale ◽  
Postpartum Depressive Symptoms ◽  
Postpartum Mothers

Air Susu Ibu (ASI) merupakan satu-satunya makanan yang sempurna dan terbaik bagi bayi karena mengandung unsur-unsur gizi yang dibutuhkan untuk pertumbuhan dan perkembangan bayi yang optimal. Namun ada beberapa penyebab ibu tidak memberikan ASI secara eksklusif seperti tidak mendapatkan dukungan dari suami/keluarga, penghasilan, usia, pendidikan yang menyebabkan terjadinya depresi postpartum sehingga menghambat proses laktasi. Tujuan penelitian untuk menyimpulkan dan memeriksa literature (examine literature) apakah gejala depresi pada ibu postpartum berhubungan dengan  keberhasilan pemberian ASI. Metode penelitian menggunakan studi appraisal dengan Critical Appraisal Joana Brigs Institute, dan metode sintesis menggunakan PEOS. Pencarian dibatasi pada studi yang diterbitkan dalam bahasa Inggris dan menyajikan data periode 2012-2019. Studi yang terindentifikasi ditinjau menggunakan PRISMA Flowchart. Studi dengan desain kuantitatif terkait gejala depresi postpartum mempengaruhi keberhasilan ASI eksklusif. Hasil penelitian adalah depresi postpartum diukur menggunakan EPDS (Edinburgh Postpartum Depression Scale) yang dilakukan pada ibu postpartum usia 2-6 minggu pascapersalinan. Gejala depresi dapat mempengaruhi keberhasilan pemberian ASI dan beberapa faktornya karena kurangnya dukungan emosional, pendidikan, pengetahuan, pendapatan yang rendah, dan terdapat riwayat depresi sebelumnya. Namun hal yang paling dominan terjadinya depresi postpartum yaitu kurangnya dukungan suami/keluarga. Kesimpulan penelitian ini adalah gejala depresi postpartum dapat mempengaruhi keberhasilan ASI eksklusif dikarenakan ada perubahan hormon dan mood yang terjadi pada ibu seperti tidak nafsu makan, gangguan tidur, cemas, sensitif sehingga dapat menggaggu kelancaran ASI. Breastmilk (ASI) is the only perfect and best food for babies because it contains nutritional elements for optimal baby growth and development. However, there are several reasons why mothers do not exclusively breastfeed, such as not getting support from their husbands/families, stage, education which causes postpartum depression which hinders the lactation process. This study aims to conclude and examine the literature (examining the literature) whether the symptoms of depression in postpartum mothers are associated with breastfeeding. The method of the study using appraisal study using Joana Brigs Institute Critical Appraisal, and synthesis method using PEOS. Base search on studies published in English and present data for the period 2012-2019. Identified studies were reviewed using PRISMA Flowchart. A quantitative design study of postpartum depressive symptoms affects exclusive breastfeeding. The results showed postpartum depression was measured using the EPDS (Edinburgh Postpartum Depression Scale) which was performed on postpartum mothers aged 2-6 weeks postpartum. Depressive symptoms can affect the situation of offering breast milk and several factors due to emotional support, education, low income, a previous history of depression. But the worst thing that happens in postpartum depression is support from family. The conclusion was postpartum depressive symptoms can affect exclusive breast milk because there are hormonal and mood changes that occur in the mother such as lack of appetite, sleep disturbances, anxiety, sensitivity so that they can interfere with the smoothness of breast milk.  

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