scholarly journals Establishing biotic stress tolerance of maize (Zea mays L.) by measuring hydroxamic acid contents

2018 ◽  
pp. 107-112
Author(s):  
Péter Makleit ◽  
Dóra Frommer ◽  
Szilvia Veres
Keyword(s):  
Acid Content ◽  
Hydroxamic Acid ◽  
Hydroxamic Acids ◽  
Main Task ◽  
Cyclic Hydroxamic Acids ◽  
The Difference ◽  
High Level ◽  
Cyclic Hydroxamic Acid ◽  
Infiltration Method ◽  
Different Levels

  Cyclic hydroxamic acids are the most considerable secondary metabolites in grasses and their main task is to protect these species from pathogens and pests. The cyclic hydroxamic acid content and common smut susceptibility were examined in our experiments. 27 maize hybrids were used for experimental plants in a climate room, where the plants were grown on a nutrient solution. An infiltration method was used for the inoculation of the plants. The total quantity of cyclic hydroxamic acids was determined and the ratio of infected plants and the ratio of inhibition was determined, too. Based on our results, on the basis of all hybrids’ data, the total hydroxamic acid content of the infected plants was higher than in the control. On the level of individual hybrids, only 9 of them had higher cyclic hydroxamic acid content in the case of infection. Increase in cyclic hydroxamic content induced by the fungus in this case is a tool for the fungus to suppress other pathogens and pests. Amongst the hybrids’ cyclic hydroxamic acid contents, significant differences were detected in the control and in the infected treatment, too. The so-called “sweetcorn” hybrids showed high level of cyclic hydroxamic acid content. According to the differences amongst hybrids, homogenous groups were created which groups differed in the case of control and infected treatment, because of the difference in increase of cyclic hydroxamic acid content. The examined hybrids showed different levels of infection and different rate of growth inhibition for the effect of inoculation. According to the infection caused damage hybrids were ranked. Infection caused notable damage for hybrids Prelude, Desszert 73, DKC5276 and DK440.

Detection of Fog Involving Heavy Pollutants by Using the New Geostationary satellite Himawari-8

2020 ◽  
Author(s):  
Hongbin Wang ◽  
Zhiwei Zhang ◽  
Duanyang Liu
Keyword(s):  
Satellite Observation ◽  
Geostationary Satellite ◽  
Japan Meteorological Agency ◽  
Composite Image ◽  
Brightness Temperatures ◽  
The Difference ◽  
Grid Points ◽  
High Level ◽  
Different Levels ◽  
Better Than

<p>Himawari-8 is the new geostationary satellite of the Japan Meteorological Agency (JMA) and carries the Advanced Himawari Imager (AHI), which is greatly improved over past imagers in terms of its number of bands and its temporal/spatial resolution. In this work, two different methods for the detection of the different levels of fog involving heavy pollutants by using the Himawari-8 were developed in China. The two different methods are the method of the difference between the 11.2 mm and 3.9 mm brightness temperatures (BTD<sub>3.9-11.2</sub>) and the method of 3.9 mm Pseudo-Emissivity (ems<sub>3.9</sub>).  The 3.9 mm Pseudo-Emissivity is the ratio of the observed 3.9 mm radiance and the 3.9 mm blackbody radiance calculated using the 11.2 mm brightness temperature. We identified the parameters optimal threshold at the 2400 stations and the grid points using the BTD<sub>3.9-11.2</sub> and ems<sub>3.9</sub> for different levels of fog involving heavy pollutants. Results on land and sea from the two methods were compared with surface observations from 2400 weather stations in China and CALIPSO (Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation) VFM (Vertical Feature Mask) products. The results show that both the method of BTD<sub>3.9-11.2</sub> and the method of ems<sub>3.9</sub> can accurately identify the different levels of fog involving heavy pollutants and the accuracy of ems<sub>3.9 </sub>method is slightly better than the BTD<sub>3.9-11.2</sub>. The accuracy of two methods has increased significantly and the false alarm rate has significantly decreased with the decrease of the visibility. When the visibility is less than 50 m, the HR, FAR and KSS of the BTD<sub>3.9-11.2</sub> method (the ems<sub>3.9 </sub>method) were 0.89 (0.90), 0.15 (0.15) and 0.74 (0.75), respectively. When mid- or high-level clouds were removed using surface temperature of the ground observations, the HR and KSS of two methods for the different levels of fog has increased significantly, and the FAR has significantly decreased. When the visibility is less than 1000 m, the HR of the BTD<sub>3.9-11.2</sub> method (the ems<sub>3.9 </sub>method) is increased to 0.81(0.85) from 0.71 (0.74), the FAR is decreased to 0.12 (0.13) from 0.27 (0.28), and the KSS is increased to 0.69 (0.72) from 0.44 (0.46). The KSS of two method increase by 0.23 and 0.26, respectively. Three cases analysis show that the fog area can be clearly identified by using the BTD<sub>3.9-11.2</sub>, ems<sub>3.9</sub> and RGB composite image. The results of the detection of sea fog by using Himawari-8 data and using CALIPSO VFM products have consistency.</p>

scholarly journals CHALLENGES FACING DISTANCE LEARNING IN THE NEGEV REGION

2021 ◽  
Vol 3 (1) ◽  
pp. 378-389
Author(s):  
Mawaheb Shehadeh ALKRRENAWI ◽  
Keyword(s):  
Distance Learning ◽  
Survey Method ◽  
Years Of Experience ◽  
Arithmetic Average ◽  
Academic Qualification ◽  
Preparatory Schools ◽  
Medium Level ◽  
The Difference ◽  
High Level ◽  
Different Levels

The study aimed to identify the level of challenges facing distance learning in preparatory schools within the Negev region from the teachers' point of view, and to reveal the difference in their views towards the challenges facing distance learning in the schools of the Negev region according to different levels of (Gender, Academic qualification, and Years of experience) variables. The study used the sample social survey method, and the questionnaire as a tool for collecting data. The study sample consisted of (302) teachers who were selected from preparatory schools in the Negev region, besides, the questionnaire was applied via websites to the targeted sample. The results showed that the total level of challenges facing distance learning in schools within the Negev region came at a High level, with an arithmetic average (3.818), as the Economic challenges area came first with an arithmetic average (4.208) and a High level, the Technological challenges area came second with an arithmetic average (4.119) and a high level, the Teacher-related challenges area came third with an arithmetic average (3.580) and a Medium level, and in the area Student-related challenges area came fourth with an Arithmetic average (3.365) and a Medium level. The results also showed that there were no statistically significant differences at the level of significance (α = 0.05) in the averages of the study sample responses about the challenges facing distance learning in the schools within the Negev region attributed to the different levels of Gender and Academic qualification variables, while there were statistically significant differences at (α = 0.05) due to the difference in the Years of experience variable in favor of those with long experience.

Difference of [Ca2+]i Movements in Platelets Stimulated by Thrombin and TRAP: the Involvement of αIIbβ3-Mediated TXA2 Synthesis

1998 ◽  
Vol 79 (06) ◽  
pp. 1184-1190 ◽  
Author(s):  
Yoshiaki Tomiyama ◽  
Shigenori Honda ◽  
Kayoko Senzaki ◽  
Akito Tanaka ◽  
Mitsuru Okubo ◽  
...  
Keyword(s):  
Platelet Aggregation ◽  
Fibrinogen Binding ◽  
Adp Release ◽  
The Difference ◽  
Txa2 Receptor Antagonist ◽  
High Level ◽  
Inhibition Studies ◽  
Peak Increase ◽  
Second Peak ◽  
Assay Conditions

SummaryThis study investigated the difference of [Ca2+]i movement in platelets in response to thrombin and TRAP. The involvement of αIIbβ3 in this signaling was also studied. Stimulation of platelets with thrombin at 0.03 U/ml caused platelet aggregation and a two-peak increase in [Ca2+]i. The second peak of [Ca2+]i, but not the first peak was abolished by the inhibition of platelet aggregation with αIIbβ3 antagonists or by scavenging endogenous ADP with apyrase. A cyclooxygenase inhibitor, aspirin, and a TXA2 receptor antagonist, BM13505, also abolished the second peak of [Ca2+]i but not the first peak, although these regents did not inhibit aggregation. Under the same assay conditions, measurement of TXB2 demonstrated that αIIbβ3 antagonists and aspirin almost completely inhibited the production of TXB2. In contrast to thrombin-stimulation, TRAP caused only a single peak of [Ca2+]i even in the presence of platelet aggregation, and a high level of [Ca2+]i increase was needed for the induction of platelet aggregation. The inhibition of aggregation with αIIbβ3 antagonists had no effect on [Ca2+]i change and TXB2 production induced by TRAP. Inhibition studies using anti-GPIb antibodies suggested that GPIb may be involved in the thrombin response, but not in the TRAP. Our findings suggest that low dose thrombin causes a different [Ca2+]i response and TXA2 producing signal from TRAP. Endogenous ADP release and fibrinogen binding to αIIbβ3 are responsible for the synthesis of TXA2 which results in the induction of the second peak of [Ca2+]i in low thrombin- but not TRAP-stimulated platelets.

ATTITUDE TO OPEN ACCESS IN RUSSIAN SCHOLARLY COMMUNITY: 2018. SURVEY RESULTS AND ANALYSIS

2018 ◽  
Vol 1 (1) ◽  
pp. 6-21 ◽  
Author(s):  
I. K. Razumova ◽  
N. N. Litvinova ◽  
M. E. Shvartsman ◽  
A. Yu. Kuznetsov
Keyword(s):  
Open Access ◽  
Open Access Publishing ◽  
Scholarly Community ◽  
Research Areas ◽  
Survey Results ◽  
The Difference ◽  
Policies And Programs ◽  
The Uk ◽  
High Level ◽  
Access Policies

Introduction. The paper presents survey results on the awareness towards and practice of Open Access scholarly publishing among Russian academics.Materials and Methods. We employed methods of statistical analysis of survey results. Materials comprise results of data processing of Russian survey conducted in 2018 and published results of the latest international surveys. The survey comprised 1383 respondents from 182 organizations. We performed comparative studies of the responses from academics and research institutions as well as different research areas. The study compares results obtained in Russia with the recently published results of surveys conducted in the United Kingdom and Europe.Results. Our findings show that 95% of Russian respondents support open access, 94% agree to post their publications in open repositories and 75% have experience in open access publishing. We did not find any difference in the awareness and attitude towards open access among seven reference groups. Our analysis revealed the difference in the structure of open access publications of the authors from universities and research institutes. Discussion andConclusions. Results reveal a high level of awareness and support to open access and succeful practice in the open access publications in the Russian scholarly community. The results for Russia demonstrate close similarity with the results of the UK academics. The governmental open access policies and programs would foster the practical realization of the open access in Russia.

Quantitative indicators of air traffic controllers’ attitude to the danger of errors

2020 ◽  
pp. 68-78
Author(s):  
O. M. Reva ◽  
V. V. Kamyshin ◽  
S. P. Borsuk ◽  
V. A. Shulhin ◽  
A. V. Nevynitsyn
Keyword(s):  
Human Factor ◽  
Differential Method ◽  
Air Traffic ◽  
Professional Activity ◽  
Aviation Accidents ◽  
Air Traffic Controllers ◽  
The Difference ◽  
Level Of Significance ◽  
The Individual ◽  
High Level

The negative and persistent impact of the human factor on the statistics of aviation accidents and serious incidents makes proactive studies of the attitude of “front line” aviation operators (air traffic controllers, flight crewmembers) to dangerous actions or professional conditions as a key component of the current paradigm of ICAO safety concept. This “attitude” is determined through the indicators of the influence of the human factor on decision-making, which also include the systems of preferences of air traffic controllers on the indicators and characteristics of professional activity, illustrating both the individual perception of potential risks and dangers, and the peculiarities of generalized group thinking that have developed in a particular society. Preference systems are an ordered (ranked) series of n = 21 errors: from the most dangerous to the least dangerous and characterize only the danger preference of one error over another. The degree of this preference is determined only by the difference in the ranks of the errors and does not answer the question of how much time one error is more dangerous in relation to another. The differential method for identifying the comparative danger of errors, as well as the multistep technology for identifying and filtering out marginal opinions were applied. From the initial sample of m = 37 professional air traffic controllers, two subgroups mB=20 and mG=7 people were identified with statisti-cally significant at a high level of significance within the group consistency of opinions a = 1%. Nonpara-metric optimization of the corresponding group preference systems resulted in Kemeny’s medians, in which the related (middle) ranks were missing. Based on these medians, weighted coefficients of error hazards were determined by the mathematical prioritization method. It is substantiated that with the ac-cepted accuracy of calculations, the results obtained at the second iteration of this method are more ac-ceptable. The values of the error hazard coefficients, together with their ranks established in the preference systems, allow a more complete quantitative and qualitative analysis of the attitude of both individual air traffic controllers and their professional groups to hazardous actions or conditions.

Chemosensitizing Activity of Histone Deacetylases Inhibitory Cyclic Hydroxamic Acids for Combination Chemotherapy of Lymphatic Leukemia

2018 ◽  
Vol 18 (4) ◽  
pp. 365-371 ◽  
Author(s):  
Denis V. Mishchenko ◽  
Margarita E. Neganova ◽  
Elena N. Klimanova ◽  
Tatyana E. Sashenkova ◽  
Sergey G. Klochkov ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Acute Toxicity ◽  
Histone Deacetylases ◽  
Hydroxamic Acids ◽  
Water Soluble ◽  
Male Rat ◽  
Hybrid Male ◽  
Cyclic Hydroxamic Acids

Background: Anti-tumor effect of hydroxamic acid derivatives is largely connected with its properties as efficient inhibitors of histone deacetylases, and other metalloenzymes involved in carcinogenesis. Objective: The work was aimed to (i) determine the anti-tumor and chemosensitizing activity of the novel racemic spirocyclic hydroxamic acids using experimental drug sensitive leukemia P388 of mice, and (ii) determine the structure-activity relationships as metal chelating and HDAC inhibitory agents. Method: Outbreed male rat of 200-220 g weights were used in biochemical experiments. In vivo experiments were performed using the BDF1 hybrid male mice of 22-24 g weight. Lipid peroxidation, Fe (II) -chelating activity, HDAC fluorescent activity, anti-tumor and anti-metastatic activity, acute toxicity techniques were used in this study. Results: Chemosensitizing properties of water soluble cyclic hydroxamic acids (CHA) are evaluated using in vitro activities and in vivo methods and found significant results. These compounds possess iron (II) chelating properties, and slightly inhibit lipid peroxidation. CHA prepared from triacetonamine (1a-e) are more effective Fe (II) ions cheaters, as compared to CHA prepared from 1- methylpiperidone (2a-e). The histone deacetylase (HDAC) inhibitory activity, lipophilicity and acute toxicity were influenced by the length amino acids (size) (Glycine < Alanine < Valine < Leucine < Phenylalanine). All compounds bearing spiro-N-methylpiperidine ring (2a-e) are non-toxic up to 1250 mg/kg dose, while compounds bearing spiro-tetramethylpiperidine ring (1a-e) exhibit moderate toxicity which increases with increasing lipophility, but not excite at 400 mg/kg. Conclusion: It was shown that the use of combination of non-toxic doses of cisplatin (cPt) or cyclophosphamide with CHA in most cases result in the appearance of a considerable anti-tumor effect of cytostatics. The highest chemosensitizing activity with respect to leukemia Р388 is demonstrated by the CHA derivatives of Valine 1c or 2c.

scholarly journals Aircraft Requirements for Sustainable Regional Aviation

Aerospace ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 61
Author(s):  
Dominik Eisenhut ◽  
Nicolas Moebs ◽  
Evert Windels ◽  
Dominique Bergmann ◽  
Ingmar Geiß ◽  
...  
Keyword(s):  
Systems Engineering ◽  
System Level ◽  
Policy Initiative ◽  
The European Union ◽  
Calculation Methods ◽  
Figures Of Merit ◽  
Performance Requirements ◽  
High Level ◽  
Different Levels ◽  
The Eu

Recently, the new Green Deal policy initiative was presented by the European Union. The EU aims to achieve a sustainable future and be the first climate-neutral continent by 2050. It targets all of the continent’s industries, meaning aviation must contribute to these changes as well. By employing a systems engineering approach, this high-level task can be split into different levels to get from the vision to the relevant system or product itself. Part of this iterative process involves the aircraft requirements, which make the goals more achievable on the system level and allow validation of whether the designed systems fulfill these requirements. Within this work, the top-level aircraft requirements (TLARs) for a hybrid-electric regional aircraft for up to 50 passengers are presented. Apart from performance requirements, other requirements, like environmental ones, are also included. To check whether these requirements are fulfilled, different reference missions were defined which challenge various extremes within the requirements. Furthermore, figures of merit are established, providing a way of validating and comparing different aircraft designs. The modular structure of these aircraft designs ensures the possibility of evaluating different architectures and adapting these figures if necessary. Moreover, different criteria can be accounted for, or their calculation methods or weighting can be changed.

scholarly journals Mode Shape-Based Damage Detection Method (MSDI): Experimental Validation

2021 ◽  
Vol 11 (10) ◽  
pp. 4589
Author(s):  
Ivan Duvnjak ◽  
Domagoj Damjanović ◽  
Marko Bartolac ◽  
Ana Skender
Keyword(s):  
Boundary Conditions ◽  
Damage Detection ◽  
Mode Shape ◽  
Experimental Validation ◽  
Detection Method ◽  
Dynamic Properties ◽  
Damage Index ◽  
Main Principle ◽  
The Difference ◽  
Different Levels

The main principle of vibration-based damage detection in structures is to interpret the changes in dynamic properties of the structure as indicators of damage. In this study, the mode shape damage index (MSDI) method was used to identify discrete damages in plate-like structures. This damage index is based on the difference between modified modal displacements in the undamaged and damaged state of the structure. In order to assess the advantages and limitations of the proposed algorithm, we performed experimental modal analysis on a reinforced concrete (RC) plate under 10 different damage cases. The MSDI values were calculated through considering single and/or multiple damage locations, different levels of damage, and boundary conditions. The experimental results confirmed that the MSDI method can be used to detect the existence of damage, identify single and/or multiple damage locations, and estimate damage severity in the case of single discrete damage.

scholarly journals Mutual Impact between Clock Gating and High Level Synthesis in Reconfigurable Hardware Accelerators

Electronics ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 73
Author(s):  
Francesco Ratto ◽  
Tiziana Fanni ◽  
Luigi Raffo ◽  
Carlo Sau
Keyword(s):  
Low Power ◽  
Integrated Circuit ◽  
Systems Design ◽  
Hardware Acceleration ◽  
High Level Synthesis ◽  
Clock Gating ◽  
Technology Application ◽  
Positive Effects ◽  
High Level ◽  
Different Levels

With the diffusion of cyber-physical systems and internet of things, adaptivity and low power consumption became of primary importance in digital systems design. Reconfigurable heterogeneous platforms seem to be one of the most suitable choices to cope with such challenging context. However, their development and power optimization are not trivial, especially considering hardware acceleration components. On the one hand high level synthesis could simplify the design of such kind of systems, but on the other hand it can limit the positive effects of the adopted power saving techniques. In this work, the mutual impact of different high level synthesis tools and the application of the well known clock gating strategy in the development of reconfigurable accelerators is studied. The aim is to optimize a clock gating application according to the chosen high level synthesis engine and target technology (Application Specific Integrated Circuit (ASIC) or Field Programmable Gate Array (FPGA)). Different levels of application of clock gating are evaluated, including a novel multi level solution. Besides assessing the benefits and drawbacks of the clock gating application at different levels, hints for future design automation of low power reconfigurable accelerators through high level synthesis are also derived.

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