scholarly journals The effect of zinc supplementation in delayed preterm delivery and biometric of neonates suspected with preterm delivery in mothers suspected of having a preterm delivery

2020 ◽  
Vol 22 (1) ◽  
pp. 11-16
Author(s):  
Sheida Shabanian ◽  
Fatemeh Bayati-Eshkaftaki ◽  
Abolfazl Khoshdel ◽  
Belgheis Mohammadi ◽  
Masoud Lotfizadeh
Keyword(s):  
Serum Level ◽  
Cord Blood ◽  
Preterm Delivery ◽  
Maternal Serum ◽  
Reproductive Age ◽  
Medical Sciences ◽  
Anthropometric Parameters ◽  
Major Health Problem ◽  
Serum Zn ◽  
Age Range

Background and aims: Micronutrient deficiency in women of reproductive age is considered as a major health problem in many developing countries. Therefore, it is important to prevent micronutrient shortage before pregnancy. This study aimed to evaluate the effect of zinc (Zn) supplementation on delaying preterm delivery and biometric neonates with suspected preterm birth. Methods: In this semi-experimental study, 140 women with preterm delivery were selected by a gynecologist in the Hajar hospital of Shahrekord University of Medical Sciences in 2016. The women were divided into four groups. Then, the serum Zn level of the mother’s blood and the umbilical cord was measured First group had a normal level; Zn level in the second group was between 50-70 mg/dL; in the third group between 20-50 mg/dL; and in the fourth group fewer than 20 mg/dL. Three groups received <20-70 mg/dL oral Zn and the normal group was given a placebo. Next, the serum Zn levels of mothers were measured and recorded at the end of the eighth month and delivery time. Infant anthropometric parameters at birth, 1 month to 3 months were measured as well. Overall, 71 (50%) and 69 (49.3%) infants were males and females, respectively. The data were analyzed using descriptive statistics and analytical statistics tests. Results: The average age of 140 pregnant women was 30.39±5.33 years old and their age range was between 18 and 41 years. In addition, the maternal Zn serum level was 56.52±33.38 mg/dL on admission and the serum level on the cord blood at birth was 53.22 ± 66.94 μg/ dL. A significant relationship was reported between the level of serum Zn on cord blood and the maternal serum Zn level on admission with growth in babies at birth and the first, second, and third month (P<0.05). Conclusion: In general, Zn is effective in children’s growth and the use of Zn supplementation can be suggested during pregnancy.

scholarly journals Maternal Serum Interleukin6 Level in Correlation with Preterm Delivery

2015 ◽  
pp. 185-189
Author(s):  
Noviyanti Noviyanti ◽  
Hermie M M Tendean ◽  
Juneke J Kaeng
Keyword(s):  
Serum Level ◽  
Preterm Delivery ◽  
Gestational Age ◽  
Sampling Method ◽  
Cross Sectional Study ◽  
Maternal Serum ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significance Level ◽  
Consecutive Sampling

Objective: To determine the correlation between maternal serum Interleukin-6 (IL-6) serum level with preterm delivery. Methods: We performed an observational cross-sectional study of 30 pregnant women between 21 to 36 week gestational age with and wthout labour (delivery) in Prof. Dr. RD. Kandou Hospital Manado. Samples were collected with consecutive sampling method. Data was analyzed using Mann-Whitney test with significance level of p

Relationship between Leptin Concentration in Cord Blood and Foetal Growth and Maternal Anthropometry of GDM Mothers at Delivery

1970 ◽  
Vol 25 (1) ◽  
pp. 9-13
Author(s):  
S Jahan ◽  
TR Das ◽  
KB Biswas
Keyword(s):  
Body Mass Index ◽  
Birth Weight ◽  
Cord Blood ◽  
Body Mass ◽  
Anthropometric Measurements ◽  
Anthropometric Parameters ◽  
Serum Leptin ◽  
C Peptide ◽  
Cord Serum ◽  
The Relationship

Background and Aims: Cord blood leptin may reflect the leptinemic status of a newborn at birth more accurately than the leptin values of blood collected from other sites. The present study was undertaken to determine the relationship of cord serum leptin concentration at birth with neonatal and maternal anthropometric parameters. Materials and Methods: Blood was taken from the umbilical cord of the babies at delivery. Maternal anthropometric measurements were recorded at admission for delivery. Neonatal anthropometric measurements were recorded within 48 hours after delivery. Linear regression analysis was used to explore the relationship between cord serum leptin concentration and anthropometric parameters of the baby and the mother. Both Serum leptin and serum C-peptide levels were measured by chemiluminescence-based ELISA method. Results: The leptin concentration (ng/ml, mean±SD) in cord blood was 39.13±14.44. Cord leptin levels correlated with birth weight (r=0.673, p<0.0001), ponderal index (r=0.732, p<0.0001) but it did not correlate with maternal body mass index, gestational age (r=0.135, p=0.349) at delivery or cord serum C-peptide concentration (r=-0.049, p=0.735) or placental weight (r=0.203, p=0.157). Conclusion: There are associations between cord leptin concentration at delivery and birth weight, ponderal index (PI) of the babies but not body mass index (BMI) of the mothers. High leptin levels of the baby could represent an important feedback modulator of substrate supply and subsequently for adipose tissue status during late gestation. (J Bangladesh Coll Phys Surg 2007; 25 : 9-13)

scholarly journals Maternal Vitamin D and Newborn Telomere Length

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 2012
Author(s):  
Lisa Daneels ◽  
Dries S. Martens ◽  
Soumia Arredouani ◽  
Jaak Billen ◽  
Gudrun Koppen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cord Blood ◽  
Telomere Length ◽  
First Trimester ◽  
Maternal Serum ◽  
Adverse Outcomes ◽  
Dietary Vitamin ◽  
Maternal Vitamin ◽  
Vitamin D Intake ◽  
Diet Supplements

Nutrition is important during pregnancy for offspring health. Gestational vitamin D intake may prevent several adverse outcomes and might have an influence on offspring telomere length (TL). In this study, we want to assess the association between maternal vitamin D intake during pregnancy and newborn TL, as reflected by cord blood TL. We studied mother–child pairs enrolled in the Maternal Nutrition and Offspring’s Epigenome (MANOE) cohort, Leuven, Belgium. To calculate the dietary vitamin D intake, 108 women were asked to keep track of their diet using the seven-day estimated diet record (EDR) method. TL was assessed in 108 cord blood using a quantitative real-time PCR method. In each trimester of pregnancy, maternal serum 25-hydroxyvitamin D (25-OHD) concentration was measured. We observed a positive association (β = 0.009, p-value = 0.036) between newborn average relative TL and maternal vitamin D intake (diet + supplement) during the first trimester. In contrast, we found no association between average relative TL of the newborn and mean maternal serum 25-OHD concentrations during pregnancy. To conclude, vitamin D intake (diet + supplements), specifically during the first trimester of pregnancy, is an important factor associated with TL at birth.

Eplerenone levels in maternal serum, cord blood, and breast milk during pregnancy and lactation

2021 ◽  
Author(s):  
Jumpei Saito ◽  
Asako Mito ◽  
Naho Yakuwa ◽  
Kayoko Kaneko ◽  
Hiroyo Kawasaki ◽  
...  
Keyword(s):  
Breast Milk ◽  
Cord Blood ◽  
Maternal Serum ◽  
Pregnancy And Lactation

scholarly journals 1483. Maternal Tdap Vaccination During Pregnancy and Immune Response: A Comparison Between Infants Born to Mothers Primed with Acellular or Whole Cell Pertussis Vaccines

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S743-S743
Author(s):  
Fiona Havers ◽  
Tami Skoff ◽  
Marcia Rench ◽  
Monica Epperson ◽  
Jarad Schiffer ◽  
...  
Keyword(s):  
Cord Blood ◽  
Geometric Mean ◽  
Severe Infection ◽  
The United States ◽  
Reproductive Age ◽  
Whole Cell ◽  
Primary Series ◽  
Gestational Age At Delivery ◽  
Antibody Levels ◽  
Lower Birthweight

Abstract Background Acellular pertussis (aP) vaccines replaced whole cell pertussis (wP) vaccines for the recommended childhood primary series in the United States in 1997. As women primed with aP vaccines in childhood enter reproductive age, it is unknown how maternal aP-priming will impact pertussis protection conferred to infants through Tdap (tetanus toxoid, reduced diphtheria toxoid and acellular pertussis) vaccination during pregnancy. Methods Infants born at term to women who had been vaccinated with Tdap at 27-36 weeks’ gestation and ≥ 14 days prior to delivery were included. Geometric mean concentrations (GMC) of pertussis-specific antibodies (measured in IU/mL) in umbilical cord blood of infants born to women born after 1997 (aP vaccine primed) were compared with those born to women born before 1992 (wP vaccine primed). Results 253 and 506 neonates born to aP- and wP-primed women, respectively, were included. Compared with wP-primed women, aP-primed women were younger (19.3 v. 24.5 years), more likely to be Hispanic or non-Hispanic black and to have infants with lower birthweight (3264 v. 3392 grams, p&lt; 0.01 for all). Gestation at Tdap receipt, gestational age at delivery, and interval between Tdap administration and delivery were not statistically different. Antibodies against pertussis toxin (PT) and filamentous hemagglutinin (FHA) were significantly lower among neonates born to aP-primed versus wP-primed mothers (PT: 17.3 v. 36.4, GMC ratio 0.475 (0.408 – 0.552) (Figure); FHA: 104.6 v. 121.4, GMC ratio 0.861 (0.776 – 0.958)). No significant differences were observed between the aP and wP-primed groups for anti- fimbriae (FIM) or anti-pertactin (PRN) antibodies ((FIM: 469.6 v. 577.2, GMC ratio 0.81 (CI 0.65 – 1.01); PRN 338.8 v. 292.6, GMC ratio 1.16 (CI 0.99 – 1.35)). Figure. Distribution of anti-PT antibody levels in cord blood in infants born to women who were primed with whole cell pertussis compared with acellular pertussis vaccines in childhood.* Conclusion The type of pertussis vaccine a woman received during childhood significantly impacted her response to Tdap vaccination during pregnancy; the largest reduction was in anti-PT antibodies thought to be most important in preventing severe infection in infants. These findings suggest that infants born to aP-primed women who received Tdap during pregnancy may have less passive protection against pertussis during the first months of life than those born to wP-primed women. Disclosures All Authors: No reported disclosures

scholarly journals Resistin in pregnancy: analysis of determinants in pairs of umbilical cord blood and maternal serum

Cytokine X ◽  
2021 ◽  
pp. 100052
Author(s):  
Anne FLOECK ◽  
Nina FERRARI ◽  
Christine JOISTEN ◽  
Maria T. PUTH ◽  
Brigitte STRIZEK ◽  
...  
Keyword(s):  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Maternal Serum ◽  
In Pregnancy

146: Prediction of spontaneous preterm delivery in women with preterm labor: analysis of multiple proteins in maternal serum

2012 ◽  
Vol 206 (1) ◽  
pp. S77
Author(s):  
Panagiotis Tsiartas ◽  
Rose-Marie Holst ◽  
Ulla-Britt Wennerholm ◽  
Henrik Hagberg ◽  
David Hougaard ◽  
...  
Keyword(s):  
Preterm Delivery ◽  
Preterm Labor ◽  
Maternal Serum ◽  
Spontaneous Preterm Delivery

INCIDENCE OF ABDOMINAL TUBERCULOSIS IN PATIENTS PRESENTING WITH PAIN ABDOMEN

2021 ◽  
pp. 13-15
Author(s):  
Pankaj Prasad Verma ◽  
Manjar Ali ◽  
Sanjay Singh ◽  
Vinay Pratap
Keyword(s):  
Health Care Services ◽  
Abdominal Tuberculosis ◽  
Morbidity And Mortality ◽  
Medical Sciences ◽  
Major Health Problem ◽  
Major Health ◽  
Care Services ◽  
Abdominal Symptoms ◽  
Pain Abdomen ◽  
Considerable Morbidity

Tuberculosis is a major health problem worldwide and in India continues to be responsible for considerable morbidity and mortality despite tremendous effort made in diagnosis, prophylaxis and therapy. The disease may involve any system of body but abdomen is one of the commonest site of involvement after lungs. This study is carrying to nd out Incidence of Abdominal Tuberculosis in patients of pain abdomen presenting as acute/chronic cases. The present study was carried out in the Department of Surgery, Rajendra Institute of Medical Sciences, Ranchi, from April 2018 to September 2019. The total number of cases selected disease remains early detection. A continual awareness on the part of the clinician of the possibility of abdominal Tuberculosis in many patients with obscure abdominal symptoms should avoid errors and aid in the detection of a condition, which if treated early, not only produces remarkable remission and relief on the part of for this study was 1800. According to the presentation, the patients were clinically divided into 2 broad groups: those who were admitted as acute emergencies and those who came with a chronic presentation. From these two groups 100 cases were fall in our inclusion criteria. Of these 100 patients, most were in their third or fourth decades of life, and females were approx two times more commonly affected as their male counterparts, maintaining an approximate ratio of 1.86:1. Thus we had a 5.55 % incidence of abdominal Tuberculosis in this series. The development of cheap and efcient procedures for early diagnosis remains one of the practical problems to battle this disease, because the only way to decrease morbidity and mortality of this the patients but also takes unnecessary burden off the health care services.

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