Prevalence of Depression in Pre-Organ Transplantation Patients at King Chulalongkorn Memorial Hospital

2021 ◽  
Vol 104 (7) ◽  
pp. 1146-1152
Keyword(s):  
Cognitive Impairment ◽  
Organ Transplantation ◽  
Organ Transplant ◽  
Psychosocial Assessment ◽  
Memorial Hospital ◽  
Study Cohort ◽  
Chi Square ◽  
Cross Sectional ◽  
Illicit Substance ◽  
Prevalence Of Depression

Objective: To study the prevalence of depression in pre-organ transplantation patients at the King Chulalongkorn Memorial Hospital. Materials and Methods: The present study was a cross-sectional descriptive study. The data were collected from the pre-organ transplantation patients of heart, liver, kidney, and lungs, at the King Chulalongkorn Memorial Hospital. The demographic and clinical data questionnaire, the Patient Health Questionnaire-9 in Thai version (PHQ-9-T), the Generalized Anxiety Disorder-7 in Thai version (GAD-7-T), the Thai Mental State Exam (TMSE), and the Thai Alcohol Use Disorders Identification Test (AUDIT-T) were used. The prevalence of depression and other psychiatric problems in pre-organ transplantation patients were assessed. The relationship was then analyzed using chi-square and Pearson’s correlation. Results: One hundred ten pre-organ transplant patients participated in the present study. The mean age was 50.32±12.2 years old, with 73.6% male participants. Types of organ failure composed of liver (50.9%), heart (31.8%), kidney (16.4%), and lungs (0.9%). The prevalence of depression was 23.6% with mean PHQ-9 score of 5.56. Anxiety, cognitive impairment, alcohol, nicotine or other illicit substance use disorder appeared to be less prevalent in the present study cohort. Conclusion: One in every five pre-organ transplantation patients were found to have depression. Suicide, anxiety, cognitive impairment, alcohol, and other illicit substance problems were also observed within the present study population but to a lesser extent. Therefore, the systematic pre-transplant psychiatric and psychosocial assessment are strongly recommended in Thai pre-organ transplantation patients. Keywords: Depression; Psychiatric prevalence; Pre-organ transplantation patients

scholarly journals Exploring the Epidemiology of Cancer after Solid Organ Transplantation (EpCOT): an observational cohort study

BMJ Open ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. e043731
Author(s):  
Adnan Sharif ◽  
Javeria Peracha ◽  
David Winter ◽  
Raoul Reulen ◽  
Mike Hawkins
Keyword(s):  
Organ Transplantation ◽  
Record Linkage ◽  
Solid Organ Transplantation ◽  
Organ Transplant ◽  
Solid Organ Transplant ◽  
Study Cohort ◽  
Solid Organ ◽  
Post Transplantation ◽  
Increased Risk ◽  
Risk Of Cancer

IntroductionSolid organ transplant patients are counselled regarding increased risk of cancer (principally due to their need for lifelong immunosuppression) and it ranks as one of their biggest self-reported worries. Post-transplantation cancer is common, associated with increased healthcare costs and emerging as a leading cause of post-transplant mortality. However, epidemiology of cancer post-transplantation remains poorly understood, with limitations including translating data from different countries and national data being siloed across different registries and/or data warehouses.Methods and analysisStudy methodology for Epidemiology of Cancer after Solid Organ Transplantation involves record linkage between the UK Transplant Registry (from NHS Blood and Transplant), Hospital Episode Statistics (for secondary care episodes from NHS Digital), National Cancer Registry (from cancer registration data hosted by Public Health England) and the National Death Registry (from NHS Digital). Deterministic record linkage will be conducted by NHS Digital, with a fully anonymised linked dataset available for analysis by the research team. The study cohort will consist of up to 85 410 solid organ transplant recipients,who underwent a solid organ transplant in England between 1 January 1985 and 31 December 2015, with up-to-date outcome data.Ethics and disseminationThis study has been approved by the Confidentiality Advisory Group (reference: 16/CAG/0121), Research Ethics Committee (reference: 15/YH/0320) and Institutional Review Board (reference: RRK5471). The results of this study will be presented at national and international conferences, and manuscripts with results will be submitted for publication in high-impact peer-reviewed journals. The information produced will also be used to develop national evidence-based clinical guidelines to inform risk stratification to enable risk-based clinical follow-up.Trial registration numberNCT02991105.

KEJADIAN DEPRESI PADA REMAJA MENURUT DUKUNGAN SOSIAL DI KABUPATEN JEMBER

2021 ◽  
Vol 3 (2) ◽  
pp. 92-101
Author(s):  
Adi Zayd Bintang ◽  
Ayik Mirayanti Mandagi
Keyword(s):  
Social Support ◽  
Random Sampling ◽  
Quantitative Research ◽  
Chi Square ◽  
Cross Sectional ◽  
Significance Level ◽  
Prevalence Of Depression ◽  
Chi Square Test ◽  
Effective Role ◽  
The Relationship

ABSTRACTDepression is a mental health problem that mostly occurs during adolescence. Physical, cognitive and emotional changes experienced during adolescence can cause stress. The prevalence of depression in adolescence has a very high increase compared to the age of children and adults. The main factor in being able to cure depression in adolescents is social support (Depkes, 2007). This study aims to identify depressive symptoms in adolescents and to find out the relationship between social support factors and depression incidence. This research is a quantitative research, with the type of observational analytic research with a cross sectional approach involving students at SMA XY in Jember Regency in May 2020. The analytical method uses the Chi Square test to see the relationship between independent and dependent variables with a significance level of α ≤ 0, 05. Data collection tool using google form. Determination of respondents by random sampling with a total of 158 respondents. The results of this study indicate that the distribution of women is 76.58% more than that of men. Based on the distribution of social support, 56.96% received good social support, while based on the incidence of depression, 54.43% did not experience depression. From the statistical test, the significance value of <0.05 indicates that there is a relationship between social support factors and the incidence of depression. Social support plays an effective role in overcoming depression experienced by adolescents.Keywords: Depression, Teens, social support. ABSTRAKDepresi merupakan salah satu masalah kesehatan mental yang sebagian besar terjadi pada masa remaja. Perubahan fisik, kognitif dan emosional yang dialami pada masa remaja dapat menimbulkan stress. Prevalensi depresi pada usia remaja memiliki peningkatan yang sangat tinggi dibandingkan dengan usia anak-anak dan usia dewasa. Faktor utama untuk dapat menyembuhkan depresi pada remaja yaitu dukungan sosial (Depkes, 2007). Penelitian bertujuan untuk mengidentifikasi gejala depresi pada remaja dan mengetahui mengenai Hubungan Faktor Dukungan Sosial dengan Kejadian Depresi. Penelitian ini adalah penelitian kuantitatif, dengan jenis penelitian analitik observasional dengan pendekatan cross sectional yang melibatkan siswa di SMA XY di Kabupaten Jember pada Bulan Mei tahun 2020. Metode analisis menggunakan uji Chi Square untuk melihat hubungan variabel independen dan dependen dengan tingkat kemaknaan α ≤ 0,05. Alat pengumpulan data menggunakan google form. Penentuan responden secara random sampling dengan jumlah 158 reponden. Hasil penelitian ini menunjukan distribusi perempuan 76,58% lebih banyak daripada laki-laki, berdasarkan distribusi dukungan sosial sebesar 56,96% mendapatkan dukungan sosial yang baik, sedangkan berdasarkan kejadian depresi sebesar 54,43% tidak mengalami depresi. Dari uji statistik nilai signifikansi sebesar < 0,05 menunjukkan bahwa ada hubungan antara faktor dukungan sosial dengan kejadian depresi. Dukungan sosial berperan efektif dalam mengatasi depresi yang dialami remaja.Kata Kunci: Depresi, Remaja, Dukungan Sosial.

scholarly journals A High Prevalence Rate of a Positive Screen for Cognitive Impairment in Patients With Human Immunodeficiency Virus Attending an Irish Clinic

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Patricia H. McNamara ◽  
Robert Coen ◽  
Janice Redmond ◽  
Colin P. Doherty ◽  
Colm Bergin
Keyword(s):  
Human Immunodeficiency Virus ◽  
Cognitive Impairment ◽  
Large Scale ◽  
Screening Program ◽  
Cross Sectional Study ◽  
Hiv Positive ◽  
Study Cohort ◽  
Cross Sectional ◽  
Positive Screen ◽  
Immunodeficiency Virus

Abstract Background Human immunodeficiency virus (HIV)-associated neurocognitive disorders occurs in 20%–50% of HIV-positive patients. We undertook this study to assess the prevalence of a positive screen for cognitive impairment in the clinic population at our institution and to demonstrate the feasibility of implementing a screening program in routine clinical encounters. Methods This was a cross-sectional study, and patients were recruited prospectively between December 2010 and February 2013. Inclusion criteria were as follows: patients were HIV positive, over the age of 18, capable of giving informed consent, and had sufficient ability to communicate in English. Patients were screened for cognitive impairment using the Brief Neurocognitive Screen. Results A total of 604 patients were recruited, and 51.5% had a positive screen for cognitive impairment. The majority of the study cohort were male (78.8%), mean age was 40.9 (standard deviation, 10.2) years, 70.9% were Irish, the most common mode of transmission was men who have sex with men (49.3%), 83% were on antiretroviral therapy, and 88.7% were virally suppressed. Logistic regression showed that the main factors predictive of a positive screen for cognitive impairment were the endorsement of cognitive symptoms (P = .024), being born in Africa (P &lt; .000001), the use of benzodiazepines (P = .00341), being unemployed (P = .008), and consumption of more than 40 units of alcohol weekly (P = .035). There was a positive screen for depression in 9.1% and a positive screen for anxiety in 24.5%. Conclusions The study highlights the necessity for a structured, prospective, large-scale screening program for cognitive impairment across countries with limited resources and demonstrates the feasibility of easily implementing this with minimal training.

scholarly journals A-233 Incremental Utility of the Montreal Cognitive Assessment (MoCA) Memory Index Score (MIS) for Detection of Cognitive Impairment

2020 ◽  
Vol 35 (6) ◽  
pp. 1028-1028
Author(s):  
Bain K ◽  
Marceaux J ◽  
Kruzelock A
Keyword(s):  
Cognitive Impairment ◽  
Classification Accuracy ◽  
Clinical Sample ◽  
Cross Sectional Study ◽  
Index Score ◽  
Neurocognitive Disorder ◽  
Chi Square ◽  
Cross Sectional ◽  
Neuropsychological Evaluations ◽  
Chi Square Analysis

Abstract Objective To investigate the incremental utility of the optional MoCA Memory Index Score (MIS) for detection of cognitive impairment. Method This cross-sectional study utilized data collected from a mixed clinical sample of 153 veterans referred for clinical neuropsychological evaluations at a VA hospital. The sample was 87% male (n = 133), with an average age of 63.23 years (range 20–91) and average education level of 13.6 years (range 6–20). All participants completed the MoCA, including the MIS items. Participants meeting criteria for mild (n = 66) or major neurocognitive disorder (n = 24) were classified as cognitively impaired (CI). Sixty-three participants who did not meet criteria for a neurocognitive disorder were classified as having no cognitive impairment (NCI). Chi square analysis and logistic regression were utilized to determine the sensitivity of the MoCA total score for detection of cognitive impairment, and to determine whether the MIS significantly improved classification accuracy. Results The MoCA total score was a significant predictor of cognitive impairment status (X2 = 40.92, p &lt; .001), with 73% sensitivity, 67% specificity, and 71% classification accuracy. When the MIS was added, the model retained significance (X2 = 41.13, p &lt; .001), but overall sensitivity, specificity, and classification accuracy were unchanged; MIS was not a significant predictor in the combined model. Conclusions The optional MIS score did not significantly improve the sensitivity of the MoCA for detection of cognitive impairment.

scholarly journals PREDICTORS OF INSOMNIA IN INDIVIDUALS WITH MILD COGNITIVE IMPAIRMENT

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S464-S464
Author(s):  
Meghan Mattos ◽  
Eric M Davis ◽  
Carol Manning
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Data Set ◽  
Specialized Care ◽  
Using Data ◽  
Cognitive Problems

Abstract Insomnia is a common disorder that affects up to 40% of people age 65 and older. Untreated insomnia can decrease quality of life, increase healthcare use, and exacerbate cognitive problems. Individuals with cognitive impairment experience more sleep disorders than those without cognitive concerns, yet little is known about insomnia and mild cognitive impairment (MCI). Our objective was to examine predictors of insomnia in persons with MCI (PwMCI). Using data from the National Alzheimer’s Coordinating Center Uniform Data Set, a cross-sectional study of older PwMCI was conducted. Independent sample t-tests and contingency tables with chi-square tests of independence were used to examine differences between PwMCI with and without insomnia. Multivariate binary logistic modeling was performed. The total sample (N=1543) was comprised of 234 (15.1%) with clinician-reported insomnia and 1309 (84.9%) without insomnia. PwMCI and insomnia were more likely to be younger, take more medications, and smoke cigarettes (p.05). Three variables significantly predicted insomnia in PwMCI subjects in a multivariate model: active depression (OR 1.66, 95%CI 1.21, 2.27), active anxiety (OR 2.16, 95%CI 1.57, 2.99) and arthritis (OR 1.78, 95%CI 1.33, 2.39). Differences in predictors of insomnia in PwMCI highlight the need for geriatric and mental health specialists to provide specialized care to this population. Future studies should examine conversion of PwMCI with insomnia to dementia and the compounding effects of insomnia on cognition.

scholarly journals Predicting Depression among Jordanian Adults with Disabilities According to the International Classification of Functioning, Disability and Health: A Pilot Study

Disabilities ◽  
2021 ◽  
Vol 1 (4) ◽  
pp. 450-458
Author(s):  
Megan Griffin ◽  
Bria Mitchell-Gillespie ◽  
Hiba Hashim ◽  
Rawan AlHeresh
Keyword(s):  
Pilot Study ◽  
Physical Disability ◽  
International Classification Of Functioning ◽  
Comorbid Condition ◽  
Chi Square ◽  
Cross Sectional ◽  
Prevalence Of Depression ◽  
Patient Health ◽  
Cross Sectional Design

Individuals with disabilities face marginalization in society and are more likely to experience depression compared to the general population. Despite this, the health system in Jordan is not adequately equipped to screen for or manage depression as a comorbid condition. A pilot study using a cross-sectional design was used for this study. Eligible participants were between the ages of 18 and 85, had a physical disability and resided in Jordan. Depression was measured using the Patient Health Questionnaire-9, and risk factors were measured using a sociodemographic survey. Descriptive statistics were used to report on the prevalence of depression and Chi square and Kendall Tau B tests were used to identify relationships between independent variables and depression. The study found that 40.62% of the sample met the criteria for depression. Those who were not married were found to be at higher risk for depression. The analysis also demonstrated that the number of people in a household was positively correlated with depression. This study fills in gaps concerning the prevalence of depression and its correlates among Jordanian adults with a physical disability. Professionals in Jordan, including rehab specialists, have a role in both screening for and preventing depression, and this study acts as a point of reference for these professionals. This pilot study may initiate larger studies to better understand this relationship in Jordan.

Awareness regarding organ transplantation among visitors of the ICU patients in three tertiary care centres in Kathmandu, a cross-sectional study

2021 ◽  
Vol 10 (1) ◽  
pp. 26-28
Author(s):  
Gentle S. Shrestha ◽  
Amit S Bhattarai ◽  
Tseten Yonjen ◽  
Ramesh S Bhandari ◽  
Paleswan J Lakhey ◽  
...  
Keyword(s):  
Brain Death ◽  
Organ Transplantation ◽  
Organ Procurement ◽  
Tertiary Care ◽  
Organ Transplant ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Adequate Knowledge ◽  
Organ Failures ◽  
Knowledge And Attitude

Background and aims: Organ transplant is often the only viable treatment option for various end stage organ failures. Inadequacy of organ procurement from living as well as cadaveric donors is common, more so in developing countries. The aim of this study was to find out the knowledge and attitude regarding organ transplantation. Methods: A questionnaire-based survey was carried out among 150 respondents, who were the visitors of patients admitted to ICU of three tertiary care centres in Kathmandu. Results: Majority of the respondents were male 105 (70%) and 132 (88%) were aware about organ transplant. Likewise, 111 respondents (84.1%) hold the belief that organ transplant save lives. Ninety-four of the responses (34.8%) believe that media was the source of knowledge and 121 (91.7 %) of the respondents stated that organ transplant should be promoted. Majority of them, 80 of the total respondents (60.6%) believed that organ can be donated by both living and deceased donors and 111 (84.1%) of them believed that organ transplant save lives. While 88 of the respondents (66.7%) have heard about brain death, 60 of them (45.4%) believe that there is an organ transplant act in Nepal. Out of all respondents who are aware about transplantation, 91 of them (68.9%) have opinion that they are willing to donate the organ of their beloved ones should there be a situation of brain death. Conclusions: The study concludes that respondents have adequate knowledge regarding organ transplantation. Respondents have overall positive attitude towards organ donation and transplantation.  

scholarly journals Assessment of depression among medical students during COVID-19 in a southern state of India

2021 ◽  
Author(s):  
Jilu Anna Mathew ◽  
Evin Siby ◽  
Arun George Alex ◽  
Gouri Krishna B. S. ◽  
Merlin Moni ◽  
...  
Keyword(s):  
Medical Students ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Southern State ◽  
Medical College ◽  
Student Community ◽  
Psychological Disturbances ◽  
Prevalence Of Depression ◽  
Chi Square Test

Background: The COVID-19 lockdown has caused increased psychological disturbances among the student community. Medical students are susceptible to mental stressors and thus more likely to be affected by the pandemic. The aim of the study was to determine the prevalence of depression, anxiety and stress in medical students during the COVID-19 lockdown in Kerala along with the associated socio-demographic factors.Methods: A web-based cross-sectional study was conducted among medical students during COVID-19 lockdown in a southern state of India. Collected data included socio-demographic details and depression, anxiety and stress scale-21 (DASS-21). Chi square test was used to determine the association of depression, anxiety and stress with the socio-demographic factors.Results: A total of 760 students were invited to partake in this study. 702 satisfied the inclusion criteria and completed the evaluation, giving a response rate of 92.4%. Among the participants 67.4% were female and 32.6% were males. Prevalence of depression, anxiety and stress among medical students were 55.1%, 33.2% and 29.4% respectively. It was found that both male and female students experienced the same levels of depression (p=0.533) during the pandemic. Students studying in private self-financing medical colleges experienced more anxiety compared to students at government medical college (p=0.008) during the pandemic. It was also observed that prevalence of depression (58.4%) was highest among first year medical students.Conclusions: The study revealed that depression, anxiety and stress were prevalent in majority of medical students during the pandemic.

scholarly journals Prevalence and severity of depression among people residing in flood affected areas of Kerala

2019 ◽  
Vol 6 (3) ◽  
pp. 1143
Author(s):  
Jose Jom Thomas ◽  
B. Prakash ◽  
Praveen Kulkarni ◽  
M. R. Narayana Murthy
Keyword(s):  
Mental Health ◽  
Statistical Tests ◽  
Severe Depression ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Symptoms Of Depression ◽  
Prevalence Of Depression ◽  
Severity Of Depression

Background: The world is witnessing significant change in its climate leading to an increase in natural disasters. Kerala state of India recently witnessed its worst Monsoon rainfall in the century. Floods have significant effects on mental health. Screening of psychological problems is necessary in the background of recent floods in Kerala. So this study was done with the objectives to assess the prevalence of depression in the flood affected people of Kerala and to assess the severity of depression among people residing in flood affected areas of Kerala.Methods: Cross sectional study was done four weeks after flood. Individuals aged ≥15 years residing in flood affected areas were included and people not willing to participate were excluded. Purposive sampling was done and 306 participants were studied. Participants were assessed by interview technique using PHQ9 questionnaire. Data was analysed using SPSS-22. Descriptive statistics like percentage were applied. Inferential statistical tests like chi-square test were applied for association.Results: Among the participants 48% showed symptoms of depression. 28.10 % were mildly depressed, 12.74% were moderately depressed, 5.56% had moderately severe and 1.63% had severe depression. Maximum prevalence of depression was observed in geriatric age group.Conclusions: A significant amount of people residing in flood affected areas showed signs and symptoms of depression. An urgent intervention is therefore required to improve mental health status of the flood affected individuals. 

scholarly journals Hubungan Antara Penggunaan Kosmetik Terhadap Terjadinya Akne Vulgaris di Poliklinik Kulit Kelamin Royal Prima dan Murni Teguh Memorial Hospital Kota Medan

2020 ◽  
Vol 6 (1) ◽  
pp. 22-25
Author(s):  
Joice Sonya Panjaitan
Keyword(s):  
Sampling Method ◽  
Acne Vulgaris ◽  
Cross Sectional Study ◽  
Memorial Hospital ◽  
P Value ◽  
Common Disease ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Akne Vulgaris

Background: Acne vulgaris is the eighth most common disease in the world, with a 9.4% prevalence. Some studies reported that cosmetics’ use could cause and aggravate acne vulgaris. This study was aimed to explore the relation between use of cosmetics on the severity of acne vulgaris.  Methods: This was a cross-sectional study from 94 patients in the Dermato-Venereology Clinic in Royal Prima Hospital and Murni Teguh Memorial Hospital Medan in 2019. Subjects were selected by accidental sampling method. The data evaluated in this study were the severity of acne vulgaris measured by the Global Acne Grading System (GAGS) and  the level of cosmetic use indicated by Cumulative Cosmetic Exposure Index (CCEI). The relation between variables were analyzed using chi-square.  Results: There was no difference between the rates of use of cosmetics on the severity of acne vulgaris (p-value = 0.532).  Conclusion: Quantitative use of cosmetics does not affect the severity of acne vulgaris.        

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