scholarly journals GAMBARAN PERTUMBUHAN PADA ANAK DENGAN RIWAYAT ASMA DI RSUP PROF. DR. R. D. KANDOU

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Prima Kinanti ◽  
Vivekenanda Pateda ◽  
Audrey M. I. Wahani

Abstract: Asthma is a chronic inflammatory disorder of the airways that causes increased airway hyperresponsiveness which triggers symptoms such as wheezing, breathlessness, chest tightness and coughing, especially at night or early morning. Asthma as a chronic disease in general may affect a child's growth through several factors. The purpose of this study was to determine the growth in children with a history of asthma who were treated in the Division of Pediatric, Prof. Dr. R. D. Kandou Hospital Manado. Research conducted a retrospective descriptive univariate data analysis. Samples were pediatric patients aged 5-18 years with a primary diagnosis of asthma treated in the Division of Pediatric, Prof. Dr. R. D. Kandou Hospital Manado in January 2011 - September 2015. Research data analysis using CDC-2000 growth curve. From the research, based on W / A and H / A, obtained the majority of children with normal growth. Based on the weight / height and BMI, obtained the majority of children with good nutritional status.Keywords: asthma, growth, children.Abstrak: Asma adalah gangguan inflamasi kronik saluran napas yang menyebabkan peningkatan hiperesponsif jalan napas yang menimbulkan gejala berupa mengi, sesak napas, dada terasa berat dan batuk-batuk terutama malam atau dini hari.Asma sebagai penyakit kronik secara umum dapat mempengaruhi pertumbuhan anak melalui beberapa faktor. Tujuan penelitian ini adalah untuk mengetahui pertumbuhan pada anak dengan riwayat asma yang dirawat di Bagian Ilmu Kesehatan Anak RSUP Prof. Dr.R.D. Kandou Manado.Penelitian yang dilaksanakan bersifat deskriptif retrospektif dengan analisis data univariat.Sampel penelitian ini adalah pasien anakusia 5 - 18 tahun dengan diagnosis utama asmayang dirawat di bagian Ilmu Kesehatan Anak Anak RSUP Prof.Dr.R.D. Kandou Manado pada bulan Januari 2011 – September 2015.Analisis data penelitian menggunakan kurva pertumbuhan CDC-2000. Dari hasil penelitian, berdasararkan BB/U dan TB/U, didapatkan mayoritas anak dengan pertumbuhan normal. Berdasarkan BB/TB dan IMT, didapatkan mayoritas anak dengan status gizi baik.Kata Kunci: asma, pertumbuhan, anak.

Definition 118 Symptoms and signs 118 Diagnosis 119 Management of acute asthma 120 Asthma in pregnancy 125 Discharge planning 125 ‘Asthma is a chronic inflammatory disorder of the airways in which many cells and cellular components play a role. The chronic inflammation causes an associated increase in airway hyper-responsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness and coughing, particularly at night or in the early morning. These episodes are usually associated with widespread but variable airflow obstruction that is often reversible either spontaneously or with treatment.’...


2017 ◽  
Vol 24 (4) ◽  
pp. 546-550 ◽  
Author(s):  
Marco Puthenparampil ◽  
Alberto Terrin ◽  
Lisa Federle ◽  
Matteo Gizzi ◽  
Paola Perini ◽  
...  

Combined central and peripheral demyelination (CCPD) is a rare chronic inflammatory disorder of the nervous system. We describe the case of a patient with a history of recurrent myelitis that acutely and simultaneously developed a brain tumour–like lesion and a sensitive-motor demyelinating polyneuropathy. The diagnosis of CCPD was supported by a detailed diagnostic workup. Up to date, no similar cases have been reported in the literature.


2017 ◽  
Vol 10 (1) ◽  
pp. 17
Author(s):  
Eka Bebasari ◽  
Miftah Azrin

Asthma is a chronic inflammatory disorder of the airways. Asthma gymnastics is one of rehabilitation efforts that mayimprove asthma patients lung function. This research was a cross sectional study to determine correlation of durationof asthma gymnastics with pulmonary function. Respondents were all asthma patients who follow asthma gymnasticsin Riau University Teaching Hospital and Health Center Rumbai. Data were collected with spirometry test with totalsampling. Most of respondents were in the age group 41-50 years (38.7%), female respondents 77.4%, most ofrespondents had a history of asthma in the family (61.3%), duration of asthma gymnastics more than 3 months(61.3%), asthma degree was intermittent (38,7%), level of asthma control was controlled 61.3% and spirometry testshowed that 54.8% respondent were classified obstructive. There is a moderate positive correlation between durationof asthma gymnastics with lung vital capacity with r = 0,451 and p = 0,011.


2006 ◽  
Vol 130 (4) ◽  
pp. 447-451
Author(s):  
Roberto J. Barrios ◽  
Farrah Kheradmand ◽  
La Keisha Batts ◽  
David B. Corry

Abstract Context.—Asthma has been defined as a chronic inflammatory disorder of the airways that is associated with recruitment of inflammatory cells and the clinical development of wheezing, shortness of breath, chest tightness, and cough. Asthma is a major public health issue. It affects 5% of the United States population and accounts for 2 million emergency department visits, 470 000 hospitalizations, and 4500 deaths annually. Objective.—To review the pathophysiology and characteristic pathologic patterns of this disease and discuss the possible mechanisms of production of the lesions. Data Sources.—We searched the literature using MEDLINE and OVID. We also searched related conference abstracts and bibliographies of selected studies. Conclusions.—There has been a significant evolution in our understanding of asthma. Specific pathways and mechanisms in recent years have been studied; however, numerous mediators and cell receptors have raised new questions that remain to be answered.


2021 ◽  
Author(s):  
Kevin H Hoffman ◽  
Elina Visoki ◽  
Stirling T Argabright ◽  
Grace E DiDomenico ◽  
Barbara H Chaiyachati ◽  
...  

Background: Suicidal thoughts and behavior (STB) in children are a growing health concern, and more data is needed regarding their biological underpinnings. Immune processes such as inflammation have been associated with STB, primarily in adults. Asthma is a common chronic inflammatory disorder in children and has been associated with STB in adolescent and adult populations, but data in children is lacking. We wished to study associations of asthma with childhood STB given asthmas potential as a clinically relevant model for childhood chronic immune dysregulation. Methods: Using data from the Adolescent Brain Cognitive Development (ABCD) Study (N=11,878, 52% males, mean age 9.9 years at baseline assessment and 10.9 years at 1-year follow up), we assessed associations between asthma and STB at both baseline and 1-year follow up. Results: We found that asthma at baseline assessment (n=2,214, 18.6%) is associated with STB, controlling for multiple confounders including demographics, socioeconomic factors and environmental confounders such as air pollution (odds ratio (OR)=1.2, 95%CI 1.01-1.42, P=0.039). Indicators of recently active asthma were not significantly associated with suicidality at baseline assessment (currently taking asthma medication: OR=1.22, 95%CI 0.93-1.60, P=0.146), or at 1-year follow up (past year asthma-related clinical visit: OR=1.13, 95%CI 0.87-1.47, P=0.357). Proxy-measures of asthma severity (number of asthma medications or clinical visits) did not reveal a significant dose response relationship with STB. Conclusions: Findings suggest an association between history of asthma and STB in children, which may not be related to asthma disease state. Further research is needed to investigate mechanisms underlying this relationship.


2021 ◽  
pp. 2526-2535
Author(s):  
Sarah S. Abdul-Hussein ◽  
Ekhlass N. Ali ◽  
Nawal M. F. Alkhalidi ◽  
Neihaya H. Zaki ◽  
Ali H. Ad'hiah

     Inflammatory bowel disease (IBD) is a chronic inflammatory disorder,  the etiology and pathogenesis of which have been suggested to be influenced by cytokines. Two main clinical types of IBD are recognized, namely ulcerative colitis (UC) and Crohn's disease (CD). The present study examined serum levels of two cytokines (IL-17A and IL-23) in 60 IBD patients (30 UC and 30 CD) and 30 healthy controls. The levels were correlated with age, gender, cigarette-smoking status, disease duration, family history, disease extension, symptoms, extra-intestinal manifestations, and medication. The results depicted that IL-17A level was significantly higher in UC and CD patients compared to control (45.2 ± 23.3 and 47.5 ± 34.4 vs. 15.6 ± 7.5 pg/ml, respectively; p < 0.001). Serum level of IL-23 was similarly increased in UC and CD patients compared to control (64.1± 23.7 and 62.5 ± 27.3 vs. 25.2 ± 11.1 pg/ml, respectively). However, the level of both cytokines showed no significant variation between UC and CD patients (p = 0.713 and 0.777, respectively). Distributing UC and CD patients into subgroups according to some characteristics revealed that IL-17A level was significantly increased in UC male compared to female patients (57.3 ± 18.2 vs. 34.5 ± 22.5 pg/ml; p = 0.005). It was also significantly increased in smoker UC patients compared with non-smoker patients (51.9 ± 19.4 vs. 31.6 ± 25.5 pg/ml; p = 0.022). Smoker CD patients also showed a significantly increased level of IL-23 compared to non-smoker patients (72.7 ± 28.5 vs. 52.2 ± 22.6 pg/ml; p = 0.038). In the case of family history, IL-23 level was significantly decreased in UC patients with a family history of IBD compared to CD patients with a family history (84.5 ± 24.3 vs. 50.4 ± 17.0 pg/ml.; p = 0.042). In conclusion, the present data suggest a role for IL-17A and IL-23 in the etiology and pathogenesis of UC and CD.


2011 ◽  
Vol 139 (3-4) ◽  
pp. 209-215 ◽  
Author(s):  
Danijela Vucevic ◽  
Tatjana Radosavljevic ◽  
Dusan Mladenovic ◽  
Vera Todorovic

Bronchial asthma is a chronic inflammatory disorder of the airways in which many cells play a role, in particular mast cells, eosinophils, neutrophils, T-lymphocytes and epithelial cells. In susceptible individuals this inflammation causes recurrent episodes of wheezing, breathlessness, chest tightness and cough, particularly at night and/or in the early morning. These symptoms are usually associated with variable and extensive limitations of airflow in the bronchi reversible spontaneously or by treatment. It has been shown that restrain of the effectors of stress response participate in the pathogenesis of bronchial asthma. Anger that is not expressed and frustrations may activate the limbic stress pathway. Thus, the released neurotransmitters followed by excitation thus causing psychogenic (mental or emotional) stress. It is also known that emotional stress may be responsible for the exacerbation of asthma. Namely, pronounced emotions cause hyperventilation and hypocapnia inducing bronchospasm. Certain psychological personality features are related to adaptive or inadequate body response to numerous life events. Thus, until the beginning of the last century, bronchial asthma was referred to as asthma nervosa, because clinicians clearly observed the psychological profile of patients with predominant fear of asphyxia and recurrent attacks of paroxysmal dyspnoea. Besides, increased sensitivity, repression of aggressive feelings and expressive empathy have been identified as the most frequent psychological characteristics of asthmatic patients. However, scientists are still far from a full understanding of bronchial asthma pathogenesis. The contribution of psychic factors has become meaningful in the understanding of the development of bronchial asthma. Having in mind that in the majority of patients asthma is a lifelong condition, there is a hope that further investigations of bronchial asthma psychogenesis will improve prevention and treatment of this disease.


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1378-P
Author(s):  
JANAKI D. VAKHARIA ◽  
SUNGEETA AGRAWAL ◽  
JANINE BACIC ◽  
LISA S. TOPOR

2015 ◽  
Vol 5 (3) ◽  
pp. 50
Author(s):  
Efi Yulistyowati ◽  
Endah Pujiastuti

<p align="center">ABSTRAK</p><p>Artikel hasil penelitian tentang kajian normatif keberadaan toko modern di Kota Semarang akan mengkaji mengenai keberadaan toko modern di Kota Semarang apakah sudah  memenuhi ketentuan dalam Peraturan Presiden Nomor 112 Tahun 2007. Untuk membahas permasalahan tersebut, metode pendekatan yang dipakai adalah yuridis normatif, dengan spesifikasi penelitian deskriptif analitis, metode pengumpulan datanya : studi dokumentasi dan studi kepustakaan, sedangkan metode analisis data yang dipergunakan adalah analisis kualitatif.</p><p>Hasil dari penelitian menunjukkan bahwa  keberadaan toko modern di Kota Semarang sudah memenuhi beberapa ketentuan yang ada dalam Peraturan Presiden Nomor 112 Tahun 2007, yang belum terpenuhi adalah : ketentuan Pasal 13  &amp; Pasal 15 Peraturan Presiden Nomor 112 Tahun 2007.</p><p><em>Articles of research on the normative study of the existence of modern stores in the city of Semarang will examine the existence of modern stores in the city of Semarang whether they have fulfilled the provisions in Presidential Regulation No. 112 of 2007. To discuss these problems, the approach method used is normative juridical, with the specifications of analytical descriptive research, data collection methods: documentation and literature study, while the data analysis method used is qualitative analysis.</em></p><p><em>            </em><em>The results of the study show that the existence of a modern shop in Semarang City has fulfilled several provisions in the Presidential Regulation Number 112 of 2007, which has not been fulfilled are:</em></p><p><em>p</em><em>rovisions in Article 13 </em><em>and p</em><em>rovisions Article 15</em><em> </em><em>of the Presidential Regulation Number 112 of 2007</em><em>.</em><em></em></p><p><em>Keywords: Study, Normative, Modern Shop, Semarang City.</em><em></em></p><p> </p>


2016 ◽  
Vol 1 (2) ◽  
pp. 23
Author(s):  
MUNIRAH MUNIRAH ◽  
HUSAIN SYARIFUDDIN

This study aimed to describe the value of cohesion and coherence contained in the translation of the Qur'an surah Al Zalzalah. This study was a qualitative descriptive research, research data collection techniques using three techniques namely, inventory, rading and understanding, and record keeping. The data analysis used the coding of data, classification data, and the determination of the data. The results showed that the cohesion markers used in the translation of surah Al Zalzalah discourse are: 1) reference, 2) pronouns, ie pronouns second person, and third, the relative pronoun, the pronoun pointer, pen pronouns and pronouns owner, 3 ) conjunctions, namely temporal conjunctions, coordinating conjunctions, subordinating conjunctions, and conjunctions koorelatif, and 4) a causal ellipsis. It mean that there was a coherence in the translation of surah Al Zalzalah discourse are: the addition or addition, pronouns, repetition or repetition, match words or synonyms, in whole or in part, a comparison or ratio of conclusions or results. Keywords: Cohesion, Coherence, sura Al Zalzalah AbstrakPenelitian ini bertujuan untuk mendeskripsikan nilai kohesi dan koherensi yang terdapat dalam terjemahan Al-Qur’an surah Al Zalzalah. Jenis penelitian ini termasuk jenis penelitian deskriptif kualitatif, Teknik pengumpulan data penelitian menggunakan tiga teknik yakni, inventarisasi, baca simak, dan pencatatan. Teknik analisis data menggunakan pengodean data, pengklasifikasian data, dan penentuan data. Hasil penelitian menunjukkan bahwa pemarkah kohesi yang digunakan dalam wacana terjemahan surah Al Zalzalah adalah: 1) referensi, 2) pronomina, yaitu kata ganti orang kedua, dan ketiga, kata ganti penghubung, kata ganti penunjuk, kata ganti penanya dan kata ganti empunya, 3) konjungsi, yaitu konjungsi temporal, konjungsi koordinatif, konjungsi subordinatif, dan konjungsi koorelatif, dan 4) elipsis kausal. Sarana koherensi yang terdapat di dalam wacana terjemahan surah Al Zalzalah adalah: penambahan atau adisi, pronomina, pengulangan atau repetisi, padan kata atau sinonim, keseluruhan atau bagian, komparasi atau perbandingan simpulan atau hasil.Kata Kunci: Kohesi, Koherensi, surah Al Zalzalah


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