scholarly journals Rare Infections of the Oral Mucosa

2021 ◽  
Vol 2020 (2) ◽  
pp. 1
Author(s):  
Ioanina Părlătescu ◽  
Radu Cazacu ◽  
Șerban Țovaru
Keyword(s):  
Oral Cavity ◽  
Head And Neck ◽  
Neurological Diseases ◽  
Cervical Lymphadenopathy ◽  
Clinical Pathology ◽  
Oral Infections ◽  
Clinical Appearance ◽  
Neck Area ◽  
Dental Diseases ◽  
Dental Infections

(1) Background: Oral mucosal infections are a commonly encountered clinical pathology in patients who consult dentists, mainly for dental diseases. Currently, the involvement of oral and dental infections in cardiovascular and neurological diseases, among others, is widely discussed in the literature. In the present research, we elaborated a comprehensive report on rare oral mucosal infections, including oral syphilis and head and neck tuberculosis. (2) Methods: The research was performed by the authors using three databases (PubMed, Wiley, and ScienceDirect). Scientific articles published from January 2000 to January 2020 were selected and reviewed to assess the epidemiology, symptoms, and diagnosis of oral syphilis and head and neck tuberculosis. (3) Results: Oral syphilis was mainly noticed as ulcers and secondary types of disease. Tuberculosis of the head and neck was most frequently encountered as cervical lymphadenopathy. (4) Conclusions: Rare oral infections diagnosis may be challenging due to their evolving polymorphic clinical appearance and their ability to mimic various diseases in the oral cavity and head and neck area.

Endoscopic Treatment of Amyloidosis of the Nasopharynx

1995 ◽  
Vol 9 (1) ◽  
pp. 43-48 ◽  
Author(s):  
Jonathan A. Lesserson ◽  
Douglas G. Finn
Keyword(s):  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Respiratory Tract ◽  
Head And Neck ◽  
Endoscopic Treatment ◽  
Lower Respiratory Tract ◽  
English Literature ◽  
Rare Presentation ◽  
Localized Amyloidosis ◽  
Neck Area

Amyloidosis of the nasopharynx is a rare presentation of localized amyloidosis. The majority of systemic amyloidosis cases involve the heart, gastrointestinal tract, kidneys, and upper and lower respiratory tract. Localized amyloidosis involving only one site is less common, but has been observed in the head and neck area, particularly in the larynx or the oral cavity. Amyloidosis in the nasopharynx has been reported in only seven previous cases in the English literature.

scholarly journals Lingual Cyct

2018 ◽  
Vol 1 (1) ◽  
pp. 23-27
Author(s):  
Mohammad Fattni ◽  
Fakhria Madan ◽  
Asma Refai ◽  
Kalid Bador ◽  
Najia Alhojaili
Keyword(s):  
Oral Cavity ◽  
Head And Neck ◽  
Malignant Transformation ◽  
Surgical Excision ◽  
The Body ◽  
Epidermoid Cysts ◽  
Neck Area ◽  
Transformation Potential ◽  
Sublingual Cyst ◽  
Slow Growing

Epidermoid cysts encountered throughout the body, only 7% occurs in the head and neck area, with the oral cavity accounting for only 1.6%. Intraoral this benign slow growing and painless entity is usually located in the submandibular, sublingual and sub mental region. They can cause symptoms of dysphagia and dyspnea and have a malignant transformation potential. Surgical excision is the treatment of choice. Described here is a case of gigantic sublingual cyst.

How serious are oral infections?

2004 ◽  
Vol 118 (7) ◽  
pp. 561-565 ◽  
Author(s):  
Zaid H. Baqain ◽  
Laurence Newman ◽  
Nicholas Hyde
Keyword(s):  
Antibiotic Therapy ◽  
Head And Neck ◽  
Soft Tissues ◽  
Early Recognition ◽  
Surgical Drainage ◽  
Intravenous Antibiotic ◽  
Oral Infections ◽  
The World ◽  
Life Threatening ◽  
Dental Infections

Life-threatening conditions following dental infections have been rare since antibiotics were introduced into the world of medicine. However, infections spreading through the soft tissues of the head and neck are encountered occasionally and mortality is still reported as a result of sepsis or airway embarrassment. A case of Ludwig’s angina from odontogenic infection that progressed into mediastinitis and pericarditis is presented. The steps adopted in the management of this case highlight the significance of early recognition and diagnosis of the source of deep cervical infections, the importance of securing the airway, effecting surgical drainage and aggressive intravenous antibiotic therapy.

Hidden mandibular pathology in a patient planned for radiotherapy highlighting the need for dental screening

2010 ◽  
Vol 10 (1) ◽  
pp. 65-68
Author(s):  
Anastasia F. Georgiou ◽  
S.C. Yeoh ◽  
H. Coleman
Keyword(s):  
Decision Making ◽  
Case Report ◽  
Oral Cavity ◽  
Head And Neck ◽  
Cystic Lesion ◽  
Radiographic Finding ◽  
Radiotherapy Planning ◽  
Neck Area ◽  
Dental Screening

AbstractDental assessments are important before the commencement of radiotherapy to the head and neck area to assess the teeth and associated structures lying in the treatment field and to inform the patient of the effects of radiotherapy on the oral cavity. This case report documents an incidental radiographic finding of a mandibular cystic lesion and its impact on the radiotherapy planning and decision making to proceed with radiotherapy.

scholarly journals Biocompatible and Biomaterials Application in Drug Delivery System in Oral Cavity

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Lotfollah Kamali Hakim ◽  
Mohsen Yazdanian ◽  
Mostafa Alam ◽  
Kamyar Abbasi ◽  
Hamid Tebyaniyan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Oral Cavity ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Vital Role ◽  
Biocompatible Materials ◽  
Oral Diseases ◽  
Oral Infections ◽  
Advantages And Disadvantages ◽  
Dental Diseases

Biomaterials applications have rapidly expanded into different fields of sciences. One of the important fields of using biomaterials is dentistry, which can facilitate implantation, surgery, and treatment of oral diseases such as peri-implantitis, periodontitis, and other dental problems. Drug delivery systems based on biocompatible materials play a vital role in the release of drugs into aim tissues of the oral cavity with minimum side effects. Therefore, scientists have studied various delivery systems to improve the efficacy and acceptability of therapeutic approaches in dental problems and oral diseases. Also, biomaterials could be utilized as carriers in biocompatible drug delivery systems. For instance, natural polymeric substances, such as gelatin, chitosan, calcium phosphate, alginate, and xanthan gum are used to prepare different forms of delivery systems. In addition, some alloys are conducted in drug complexes for the better in transportation. Delivery systems based on biomaterials are provided with different strategies, although individual biomaterial has advantages and disadvantages which have a significant influence on transportation of complex such as solubility in physiological environments or distribution in tissues. Biomaterials have antibacterial and anti-inflammatory effects and prolonged time contact and even enhance antibiotic activities in oral infections. Moreover, these biomaterials are commonly prepared in some forms such as particulate complex, fibers, microspheres, gels, hydrogels, and injectable systems. In this review, we examined the application of biocompatible materials in drug delivery systems of oral and dental diseases or problems.

The role of the oral cavity immune cells in the postoperative complications after face lifting

2018 ◽  
pp. 174-178
Author(s):  
Ш.М. Абрамян ◽  
Е.В. Рожнова ◽  
Е.Н. Волкова ◽  
С.Н. Блохин ◽  
С.Г. Морозов
Keyword(s):  
Oral Cavity ◽  
Immune Cells ◽  
Postoperative Period ◽  
Negative Impact ◽  
Tooth Enamel ◽  
Healing Time ◽  
Negative Contribution ◽  
Dental Diseases ◽  
Induced Apoptosis ◽  
Wound Healing Time

Цель. Изучение клеток иммунной системы полости рта у пациентов до проведения операции лифтинга лица, а также сопоставление этих данных с показателями, выявленными при осложнениях в послеоперационном периоде. Методика. Исследованы клетки иммунной системы полости рта 100 женщин (23-68 лет), которым перед операцией лифтинга лица проведено стоматологическое обследование и необходимое лечение при наличии кариеса дентина, клиновидного дефекта эмали зуба, хронического периодонтита или пульпита. Выделенные путем смывов десенной борозды клетки окрашивали моноклональными антителами и анализировали на проточном цитометре. Определяли уровень спонтанного и индуцированного апоптоза. Оценивали уровень фагоцитоза и генерацию супероксидного аниона нейтрофилами. Результаты. Показано, что хронические воспалительные заболевания зубов оказывают негативное влияние на состояние иммунных клеток ротовой полости, сопровождаются повышением генерации супероксидного аниона нейтрофилами, повышением уровня спонтанного и церамид-индуцированного апоптоза клеток десенной борозды. Заключение. Наличие хронической патологии зубов, даже после санации, оказывает негативное влияние на течение послеоперационного периода при проведении операции лифтинга лица, в частности, способствует увеличению времени заживления операционной раны, инфицированию раны с появлением очагов некроза в области операционного шва. The object. The study of the cells of the immune system of the oral cavity in patients before the operation of face lifting, as well as a comparison of these indicators with complications in the postoperative period. Methods. The immune cells from the oral cavity were studied in 100 women (23-68 years), who underwent a dental examination and necessary treatment if they had the dentin caries, wedge-shaped defect of tooth enamel, chronic periodontitis or pulpitis before the facial lifting operation. The immune cells have been isolated by a lavage of gingival sulcus around the damaged tooth. Results. It has been shown that chronic dental diseases made a negative contribution to the oral cavity immune cells. It has been accompanied by the elevated levels of superoxide originating from neutrophils as well as the increased levels of spontaneous and ceramide-induced apoptosis of immune cells isolated from the gingival sulcus. Conclusion. The presence of chronic pathology of teeth even in the case of the preoperative dental sanation has a negative impact on the postoperative period after face lifting, in particular, contributes to the lengthening of the surgical wound healing time, wound infection as well as the partial necrosis of suture.

The experience of using a diode laser in the herpes labial treatment

2020 ◽  
Vol 25 (1) ◽  
pp. 43-46
Author(s):  
S. L. Blashkova ◽  
E. V. Krikun ◽  
Yu. V. Fazylova ◽  
Yu. V. Blashkova
Keyword(s):  
Oral Cavity ◽  
Diode Laser ◽  
Comparison Group ◽  
Treatment Time ◽  
Local Treatment ◽  
Allergic Reactions ◽  
High Prevalence ◽  
Dental Diseases ◽  
Simplex Virus

Relevance. The relevance of the problem is in the high prevalence of the herpes simplex virus. According to WHO, nearly 90% of the population are carriers. Relapses can occur several times a year, which leads to disability and impairs the quality of life. Currently, there are a large number of drugs for general and local treatment. However, they are toxic and can cause allergic reactions. In recent years, a large number of studies have been devoted to the use of lasers in the treatment of dental diseases. Therefore, the question of the use of a laser in the treatment of herpetic lesions of the oral cavity remains relevant.Purpose. The research purpose was to determine the effectiveness of the use of a diode laser in the treatment of herpetic lesions of the lips.Materials and methods. We conducted a comparative assessment of the effectiveness of the use of a diode laser in monotherapy of herpetic lip lesions in 18 patients. The comparison group consisted of 18 patients, in the local treatment of which antiviral ointments were used.Results. The results of the study showed that the use of a diode laser can reduce treatment time, accelerate the epithelization of foci.Conclusion. The results of our study allow us to recommend the use of a diode laser in the complex treatment of herpetic lesions of the oral cavity.

Research of matrix metalloproteinases in therapeutic dentistry

2020 ◽  
pp. 51-57
Author(s):  
L.I. Shalamay ◽  
E.Y. Nechai ◽  
A.I. Sakerina ◽  
A.G. Gabdullin
Keyword(s):  
Matrix Metalloproteinases ◽  
Oral Cavity ◽  
Catalytic Domain ◽  
Different Types ◽  
Dental Diseases ◽  
Classification Function

This article the properties of matrix metalloproteinases, their classification, function and role in the development of dental diseases are presented. The analysis of matrix metalloproteinases has been performed, which proves their important role in the physiological and pathological processes of the oral cavity. The possibility of using matrix metalloproteinases as part of one of the methods for diagnosing diseases and using them to evaluate the effectiveness of treatment has been considered. The structure of different types of metalloproteinases, as well as a model of the catalytic domain of the MMP-8 molecule has been presented.

scholarly journals Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview

Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 271
Author(s):  
Saverio Capodiferro ◽  
Luisa Limongelli ◽  
Gianfranco Favia
Keyword(s):  
Early Diagnosis ◽  
Oral Cavity ◽  
Head And Neck ◽  
Clinical Outcomes ◽  
Systemic Disease ◽  
Clinical Manifestations ◽  
Systemic Diseases ◽  
Special Issue ◽  
Hard Tissues ◽  
Current Special Issue

Many systemic (infective, genetic, autoimmune, neoplastic) diseases may involve the oral cavity and, more generally, the soft and hard tissues of the head and neck as primary or secondary localization. Primary onset in the oral cavity of both pediatric and adult diseases usually represents a true challenge for clinicians; their precocious detection is often difficult and requires a wide knowledge but surely results in the early diagnosis and therapy onset with an overall better prognosis and clinical outcomes. In the current paper, as for the topic of the current Special Issue, the authors present an overview on the most frequent clinical manifestations at the oral and maxillo-facial district of systemic disease.

scholarly journals Neoadjuvant immunotherapy in resectable head and neck cancer: oral cavity carcinoma as a potential research model

2021 ◽  
Vol 13 ◽  
pp. 175883592098406
Author(s):  
Vanesa Gutiérrez Calderón ◽  
Alexandra Cantero González ◽  
Laura Gálvez Carvajal ◽  
Yolanda Aguilar Lizarralde ◽  
Antonio Rueda Domínguez
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Surgical Resection ◽  
Squamous Cell ◽  
Immune Checkpoint ◽  
Immune Checkpoint Inhibitors ◽  
Checkpoint Inhibitors ◽  
Research Model

Squamous cell carcinoma of oral cavity (OCSCC) accounts for approximately 25% of cases of head and neck squamous cell carcinoma (HNSCC). Tobacco and alcohol consumption are the main risk factors for both cancers. Surgical resection, combined with adjuvant radiotherapy or radiochemotherapy in patients with high risk of relapse, is the key element in management in the initial stages. However, despite the availability of aggressive multidisciplinary treatments, advanced resectable OCSCC carries poor prognosis; only half of the patients are disease-free 5 years after the surgery. Immunotherapy based on the use of immune checkpoint inhibitors has been proven to be effective in a wide variety of tumours, including recurrent and metastatic HNSCC. These positive results resulted in investigations into its effectiveness in earlier stages of the disease with OCSCC emerging as an interesting research model because of the accessible location of the tumours. This article reviews the potential advantages of emerging immunotherapeutic agents [mainly monoclonal antibodies against programmed cell death-1 ( PD-1) immune checkpoint inhibitors] as neoadjuvant treatment for OCSCC at locoregional stages as well as the ongoing clinical trials, challenges in evaluating tumour response, and possible predictive biomarkers of response with highlights regarding the role of oral microbiota as modulators of immune response. The efficacy and safety of anti- PD-1 drugs in these patients have been proven in preliminary trials. If there is a decrease in the relapse rate and an improvement in the overall survival after surgical resection in ongoing trials, preoperative immunotherapy may be established as a treatment option for patients with early stages of the disease.

Sign in / Sign up

Export Citation Format

Share Document