PROSPECTIVE CROSS SECTIONAL STUDY OF INCIDENCE AND CORRELATION OF DYSLIPIDEMIA IN PREDICTING OUTCOME OF PATIENTS DIAGNOSED WITH CEREBROVASCULAR ACCIDENT AT MMCH, MADHUBANI, BIHAR

2021 ◽  
pp. 33-34
Author(s):  
Dilip Kumar Sah ◽  
[Prof.] Ajay Kumar Lal Das ◽  
Debarshi Jana

Introduction: Lipid abnormality has been described as one of the risk factor for ischemic stroke. However, there are limited studies comparing stroke pattern (infarction and hemorrhage) with lipid prole of patients. Study aimed to study incidence and correlation of lipid abnormality in cerebrovascular accident (CVA) patients. Material And Methods: Hundred and twenty seven subjects were studied after dividing in to Cases (n=102, with CVA) and Control (n=25, without CVA) in the Department of Medicine, Madhubani Medical College and Hospital, Madhubani, Bihar between January 2020 to December 2020. Detailed history and lipid prole was recorded for each subject. Stroke pattern was analyzed using brain CT/MRI for each patient. Results: Most of the subjects among Cases and Control belong to the age groups of 61-85 years (45.09%) followed by 41-60 years (44%) respectively. Among Cases, maximum patients were males (61.76%) whereas among Control, maximum patients were females (84%). Most of the cases were smokers (53.92%). Among smokers of Case group, infarction (55%) was more common compared to hemorrhage (51%). Dyslipidemia was more common among cases (56.86%) compared to control (28%) (p=0.009). Majority of patients (63.07%) with infarct had dyslipidemia as compared to patients with hemorrhage (45.94%). Decreased high density lipoprotein (HDL) level (74%) was the main culprit among Cases followed by decreased total cholesterol (64%). Out of 14 expired patients in Cases, 71.42% had dyslipidemia. Conclusion: Decreased level of HDL was most commonly reported among ischemic compared to hemorrhagic stroke. Dyslipidemia was most commonly reported in patients who died because of stroke.

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Seung Jae Kim ◽  
Oh. Deog Kwon ◽  
Kyung-Soo Kim

Abstract Background This study aimed to investigate the prevalence, awareness, treatment, and control rates of dyslipidemia and identify the predictors of optimal control (low-density lipoprotein cholesterol < 100 mg/dL) among patients with diabetes mellitus (DM). Methods A cross-sectional study was conducted using the representative Korea National Health and Nutrition Examination Survey (2014–2018). Overall, 4311 patients with DM, aged ≥19 years, and without cardiovascular diseases were selected, and the prevalence, awareness, treatment, and control rates of dyslipidemia were calculated. Univariate and multivariate logistic regression analyses were conducted to evaluate the factors influencing the optimal control of dyslipidemia. Results Dyslipidemia was prevalent in 83.3% of patients with DM, but the awareness and treatment rates were 36.5 and 26.9%, respectively. The control rate among all patients with dyslipidemia was 18.8%, whereas it was 61.1% among those being treated. Prevalence and awareness rates were also significantly higher in women than in men. Dyslipidemia was most prevalent in those aged 19–39 years, but the rates of awareness, treatment, and control among all patients with dyslipidemia in this age group were significantly lower than those in other age groups. The predictors of optimal control were age ≥ 40 years [range 40–49 years: adjusted odds ratio (aOR) 3.73, 95% confidence interval (CI) 1.43–9.72; 50–59 years: aOR 6.25, 95% CI 2.50–15.65; 60–69 years: aOR 6.96, 95% CI 2.77–17.44; 70–79 years: aOR 9.21, 95% CI 3.58–23.74; and ≥ 80 years: aOR 4.43, 95% CI 1.60–12.27]; urban living (aOR 1.44, 95% CI 1.15–1.80); higher body mass index (aOR 1.27, 95% CI 1.13–1.42); lower glycated hemoglobin levels (aOR 0.71, 95% CI 0.67–0.76); hypertension (aOR 1.53, 95% CI 1.22–1.92); poorer self-rated health status (aOR 0.72, 95% CI 0.62–0.84); and receiving regular health check-ups (aOR 1.58, 95% CI 1.25–2.00). Conclusions Most patients with DM were diagnosed with dyslipidemia, but many were unaware of or untreated for their condition. Therefore, their control rate was suboptimal. Thus, by understanding factors influencing optimal control of dyslipidemia, physicians should make more effort to encourage patients to undergo treatment and thus, adequately control their dyslipidemia.


2021 ◽  
pp. 71-73
Author(s):  
Amit Kumar Tiwari ◽  
Umesh Chandra Jha ◽  
Debarshi Jana

INTRODUCTION:Cerebrovascular accident (commonly called stroke) is dened as an abrupt onset of a neurologic decit that is attributable to a focal vascular cause. Thus, the diagnosis of stroke is clinical and laboratory studies including brain imaging are used to support the diagnosis AIMS AND OBJECTIVES: To evaluate the serum levels of high sensitivity C-reactive protein (hsCRP) in different types of cerebrovascular accidents on admission. MATERIALS AND METHODS: This study was an institution based cross-sectional study designed to investigate the association of hs-CRP levels with stroke and its types in Indian patients. The study was done in the Department of Medicine, Darbhanga Medical College and Hospital, Laheriasarai, Bihar from march 2019 to March 2020. 50 patients of either sex above 12 years of age admitted in Medicine Department of DMCH, Laheriasarai, Bihar with clinically or radiologically diagnosed stroke. RESULT: The mean level of hsCRP (mean ± s.d.) of the cases in our study was 7.65±7.01 with range 1.4 – 26 and the median was 3.7 and 58% of the cases were having level of hsCRP≥3 (p=0.023).Mean level of hsCRPof cases was signicantly higher than that of control (t98=7.25;p=0.001). CONCLUSION:We concluded that hs-CRPlevel is increased in cases of cerebrovascular accident- ischemic as well as haemorrhagic, suggesting an inammatory response in acute cerebrovascular accident. hs-CRP level is increased in patients with ischemic cerebrovascular accident dramatically but not in haemorrhagic cerebrovascular accident which might be considered as useful adjunct method for determining type of stroke in patients with cerebrovascular problems.


1970 ◽  
Vol 9 (1) ◽  
pp. 26-29
Author(s):  
Seheli Zannat Sultana ◽  
Mohsin Khalil ◽  
Manjurul Karim Khan ◽  
Laila Anjuman Banu ◽  
Zubaida Gulshan Ara ◽  
...  

Context: The thyroid gland is the first endocrine organ to evolve in the vertebrates. It has right and left lobes and connected by narrow median isthmus which lies over the second, third and fourth tracheal rings. A conical pyramidal lobe often ascends towards the hyoid bone from isthmus or the adjacent part of either lobe. It measures about 1.25 cm transversely and vertically. Its size and site vary greatly. Isthmus is topographically related with some important anatomical structures. So this study was carried out to determine the incidence of presence & variation in anatomical position of isthmus of thyroid gland of Bangladeshi people of different age groups to establish a normal standard. Study type: Descriptive cross-sectional study. Place and period of study: Department of Anatomy, Mymensingh Medical College. from October’2004 to February’2005. Materials: The study was carried out on 60 cadavers of different age groups age ranging from 11 to 70 years. Thyroid glands were collected from unclaimed dead bodies autopsied in Forensic Medicine Department of Mymensingh Medical College. Methods: The collected specimens were divided into age group A (upto 18 years), group B (18 to 45 years), group C (above45 years). All specimens were examined morphologically by fine dissection method. Result: In the present study isthmus was present in 41 (68.33%) cases. In those thyroids which were devoid of isthmus, lobes were found to be merged with each other in the midline but in one case two lobes were found completely separated from each other. It was evident that the posterior relations of isthmus were widely variable. In only 18% cases it was found at its usual position- against the 2nd, 3rd and 4th tracheal rings. In the present study more frequent location of isthmus was found at 1st, 2nd, 3rd and 2nd, 3rd, 4th tracheal rings. In both cases their incidences were 18.3%. Conclusion: The present study will help to increase the information pool on the anatomy of thyroid gland of Bangladeshi people. To establish a normal standard for Bangladeshi people, further studies with large samples from different zones of the country are suggested. Key Word- Isthmus; Human Thyroid gland; Incidence; Posterior relation; Bangladesh DOI: http://dx.doi.org/ 10.3329/bja.v9i1.8144 Bangladesh Journal of Anatomy January 2011, Vol. 9 No. 1 pp 26-29


2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Parisa Behzadi ◽  
Firouzeh Torabi ◽  
Massoud Amini ◽  
Ashraf Aminorroaya

Oxidized low density lipoprotein (ox-LDL) is a product of oxidative stress. In this cross-sectional study, we compared the ox-LDL concentrations in diabetic patients with normoalbuminuria (n=28), microalbuminuria (n=28), and macroalbuminuria (n=28) with their first degree relatives (n=28) and healthy control people (n=31). They were selected by consecutive patient selection method. The ox-LDL level was assayed using ELISA. We measured blood pressure, lipid profile, fasting plasma glucose (FPG), and HbA1c in all groups. There was no significant difference in ox-LDL concentrations among normoalbuminuric, microalbuminuric, and macroalbuminuric diabetic groups. In diabetic patients with micro- and macroalbuminuria, ox-LDL concentration was higher than their first degree relatives (P=0.04andP=0.03) and control group (P=0.001andP=0.03, resp.). In normoalbuminuric diabetic persons, ox-LDL concentration was just higher than that of healthy people (P=0.02). There was no statistically significant difference in ox-LDL levels between normoalbuminuric diabetic patients and their first degree relatives. In conclusion, the presence and progression of albuminuria in diabetic patients are not related to ox-LDL concentration and genetic predisposition influences the plasma OX-LDL level. Larger sample size is needed to confirm this conclusion in future studies.


2012 ◽  
Vol 3 (2) ◽  
pp. 41-43
Author(s):  
Farzana Rabee Choudhury ◽  
Maliha Rashid ◽  
Ratu Rumana ◽  
ABM Zakir Uddin ◽  
Nilufar Nasrin Ava

Background: Genital prolapse is a common gynaecological problem in developing country like Bangladesh.Objectives: The aim of this study was to evaluate the advantages of short term catheterization in comparison to long term catheterization after genital prolapse surgery. Methodology: This was a prospective analytical cross sectional study being carried out from 1st July 2005 to 30th July 2006 in the Department of Gynaecology & Obstetrics of Sir Salimullah Medical College & Mitford Hospital. A total of 200 patients undergoing genital prolapse surgery were selected for this study. Patients were divided into two groups. In short term catheterization group the urinary catheter was withdrawal within one day after surgery and in the short term catheterization group the catheter was remained in situ for 5 days after surgery. Result: Positive urine culture was found in 16% in long term catheterization group compared with 6% in short term group (P=0.02). Mean duration of hospital stay was 6.98 days in long term catheterization group and 4.68 days in short term catheterization group (P<0.01). Residual volume was more than 200 ml and need for re-catheterization occurred in 3% in group whereas it was 10% in case group (P=0.04). Conclusion: This study permits to conclude that short term catheterization is better than long term catheterization. J Shaheed Suhrawardy Med Coll, 2011;3 (2): 41-43 DOI: http://dx.doi.org/10.3329/jssmc.v3i2.12077


2020 ◽  
Vol 17 (3) ◽  
pp. 81-89 ◽  
Author(s):  
Nazafatul Ain ◽  
Saira Khan ◽  
Muhammad Marwat ◽  
Nisar Khan ◽  
Iftikhar Ahmad ◽  
...  

Background: Global Health Estimates 2015 has shown the stroke as second leading global cause of death and 3rd leading global cause for DALYs for year 2015. The objectives of this study were to determine the frequency, distribution and determinants of hypertension in adult stroke population of D.I.Khan Division, Pakistan. Materials & Methods: This cross-sectional study was conducted in Department of Community Medicine, Gomal Medical College, D.I.Khan, Pakistan from February 1, 2017 to April 30, 2017. A sample 217 was selected with margin of error 5.59%, 90%CL and 50% prevalence of hypertension in 200,000 adults at risk of stroke population through consecutive sampling. All indoor adult patients of stroke were eligible. Sex, age groups, and residence and presence of hypertension were variables. Frequency and distribution of hypertension were analyzed by count and percentage. Hypotheses for distribution were substantiated by chi-square goodness-of-fit and of association by chi-square test of association. Results: Out of 217 patients with stroke, 123 (56.7%) were men and 94 (43.3%) were women, 86 (39.6%) were≤60 years and 131 (60.4%) were>60 years, and 105 (48.4%) were urban and 112 (51.6%) were rural. Frequency of hypertension was 132/217 (60.83%). Out of 132 patients with hypertension, men were 74 (34.10%), women 58 (26.73%), age group≤60 years 46 (21.20%), >60 years 86 (39.63%), urban 72 (33.18%) and rural 60 (27.65%). Presence of hypertension was associated to residence (p=.023) but not to sex (p=.817) and age groups (p=.072). Conclusion: Frequency of hypertension in adult stroke population of D.I.Khan Division, Pakistan was found to be similar as expected. Frequency was more in men, in older age group (of>60years) and in urban population. The presence of hypertension in adult stroke population of D.I.Khan Division was associated to residence but not to sex and age groups.


2022 ◽  
Vol 18 ◽  
pp. 174550652110706
Author(s):  
Mayle Andrade Moreira ◽  
Saionara Maria Aires da Câmara ◽  
Sabrina Gabrielle Gomes Fernandes ◽  
Ingrid Guerra Azevedo ◽  
Álvaro Campos Cavalcanti Maciel

Objective: This study aims to compare the prevalence of metabolic syndrome between different age groups of middle-aged and older women and to assess whether these differences are independent of potential covariates. Methods: Study conducted with 510 women divided into three age groups: 45–54, 55–64 and 65–74 years. Socioeconomic, reproductive and lifestyle variables were self-reported. We defined metabolic syndrome using the National Cholesterol Education Program Adult Treatment Panel III criteria (abdominal obesity, diabetes, reduced high-density lipoprotein, elevated triglycerides, and hypertension). Logistic regression assessed the association between age groups, and metabolic syndrome was adjusted for covariates (socioeconomic variables, age at menarche and at first childbirth, parity, menopausal status, physical activity variables and smoking). Results: Women aged 55–64 years presented higher prevalence of all metabolic syndrome criteria than the other groups, except for abdominal obesity, which was higher in the oldest group. In the fully adjusted analysis, the 55–64 years age group continues to exhibit significantly higher odds of presenting metabolic syndrome when compared to the youngest group (45–54 years) (OR = 2.257; 95% CI = 1.20:4.24). There was no statistical difference in the odds of presenting metabolic syndrome when comparing the oldest and the youngest groups (OR = 1.500; 95% CI = 0.85:2.65). Conclusion: The higher prevalence of metabolic syndrome among those aged 55–64 years may indicate that middle-aged women become unhealthy earlier in the life course and that many of them may die prematurely. This result highlights the importance of screening metabolic syndrome earlier in the midlife and the need for public health policies aimed at reducing adverse effects in later years.


BMJ Open ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. e034226
Author(s):  
Lei Feng ◽  
Shiyan Nian ◽  
Zongwu Tong ◽  
Ying Zhu ◽  
Ying Li ◽  
...  

ObjectivesThis study aimed to investigate the dynamic trends in total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) levels with ageing.DesignA Chinese population-based cross-sectional study.SettingA physical examination centre of a general hospital.ParticipantsAdult subjects (178 167: 103 461 men and 74 706 women) without a known medical history or treatments that affect lipid metabolism.Main outcome measuresDynamic trends in the above-mentioned lipid parameters with ageing were explored; turning points of age were established using age stratification and validated by fitted multivariate linear regression modelling.ResultsAge was found to be an independent factor extensively associated with lipid levels in both sexes when adjusted for serum glucose, body mass index, lifestyle, drinking and smoking. Age was positively associated with TC, logarithm-transformed TG (LnTG) and LDL-C levels in men ≤40, ≤40 and ≤60 years old (yo) and in women ≤60, ≤70 and ≤60 yo, respectively. Conversely, age correlated negatively with TC, LnTG and LDL-C levels in men ≥61, ≥41 and ≥61 yo and in women ≥61, ≥71 and ≥61 yo, respectively. TC, TG and LDL-C levels in women were initially lower than those in men but surpassed those in men in 51–55, 61–65 and 51–55 yo age groups. The trends in HDL-C levels with age were relatively irregular, although HDL-C levels in women were higher than in men for all age groups.ConclusionsThe definition of dyslipidaemia, the atherosclerotic cardiovascular disease risk assessment and the initiation/goals of statin therapy should fully consider age-related trends in lipid levels and sex differences.


2021 ◽  
Vol 1 (2) ◽  
pp. 31-34
Author(s):  
Wafa Ali ◽  
Amal Alqufly ◽  
Ibrahim Aljabr ◽  
Sharafaldeen Bin Nafisah

BACKGROUND: The resurgence of COVID-19 cases in Saudi Arabia, despite ongoing control measures, warrants further analysis. AIM: We aimed to investigate the prevalence and sociodemographic risk factors of COVID-19 in Al Qassim Province, Saudi Arabia. We explored perceptions toward vaccination, social isolation and community adherence to social distancing measures. METHODS: We collected data reported by the Weqaya, Saudi Centre for Disease Prevention and Control, and conducted a cross-sectional study within the province. RESULTS: Up to 9 May 2021, 15 497 positive cases were detected, comprising a prevalence of 1.46%. Uyun Al-Jiwa and Riyadh Al-Khabra had the highest infection rate. Our sample of 511 participants revealed an exposure rate of 52.1% (n=266) with no specific sociodemographic risk factor. Self-isolation following exposure to a confirmed or probable case occurred less among older age groups and married participants, and was not influenced by the presence of underlying chronic diseases. The majority of participants perceived community compliance with social distancing measures to fall within the ‘sometimes’ category. Finally, the vaccination acceptance rate was 72.6% (n=371). CONCLUSION: The findings of the current study emphasise the need to adopt further measures to encourage adherence to social distancing and self-isolation, especially among vulnerable groups.


2016 ◽  
Vol 5 (1) ◽  
pp. 20-26
Author(s):  
Nibedita Roy ◽  
Kamrun Nahar ◽  
Uttam Kumar Sarker ◽  
Fouzia Akter ◽  
Ayesha Beg ◽  
...  

This descriptive type of cross-sectional study of 72 cases of uterine rupture was conducted over 1 year (from September 2006 to August 2007) in the department of Obstetrics and Gynaecology, Mymensingh Medical College Hospital, Bangladesh to evaluate the maternal outcome of different types of surgery, to assess the maternal mortality and maternal morbidity. All cases of ruptured uterus which were received & treated and did not die within 30 minutes of admission are included in the study. Data were collected by preformed data collection sheet. The results showed that the common age groups were between 20-30 years in 31(68.00%) cases. Among all ruptured cases, 6 cases (8.33%) were Primigravida, 52 cases (72.22%) were between gravida 2nd to 4th and 14 cases (19.44%) were gravida 5th or above. Among all cases, 66 cases (91.66%) required blood transfusion; Subtotal hysterectomy was done in 36 cases (50.00%), total hysterectomy in 4 cases (5.56%), and repair of the rent in 32 cases (44.44%). Associated operations were done along with repair or hysterectomy in 13 (18.05%) cases. Postoperative complications were found in 23 (31.94%) cases. The shortest stay was 8 days & the longest stay was 62 days. The hospital staying was about 2 weeks in 48(66.70%) cases. Among 10 death cases (13.90%) maximum patient died within first 5 hours. The causes of maternal death were due to septicemia, renal failure and shock in 20%, 30% and 50% respectfully. CBMJ 2016 January: Vol. 05 No. 01 P: 20-26


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