scholarly journals Pengembangan Formula Gel Ekstrak Teh Hijau (Camellia sinensis L.) sebagai Penyubur Rambut

2019 ◽  
Vol 3 (1) ◽  
pp. 43
Author(s):  
Novena Yety Lindawati ◽  
Lusia Murtisiwi ◽  
Crescentiana Emy Dhurhania

Kerontokan rambut merupakan masalah yang dapat mengganggu penampilan. Ekstrak teh hijau dengan kadar 5 % terbukti menstimulasi pertumbuhan rambut (Sumakdjaja, dkk., 2008). Zat aktif dalam teh hijau (Camellia sinensis L) yang berkhasiat sebagai penyubur rambut adalah senyawa katekin dan turunannya. Senyawa flavonoid teh hijau terdiri dari epikatekin, (EC), epikatekin galat (ECG), dan epigalokatekin galat (EGCG). Selain itu juga terdapat asam galat, galokatekin galat (GCG), galokatekin (GC), katekin galat (CG) katekin (C), vitamin B dan vitamin C (Agus, 2007) yang mampu memperkuat akar rambut, mencegah kerontokan rambut, menghambat radikal bebas, menetralkan racun, dan melindungi kulit kepala dari infeksi. Formula sediaan kosmetik dan makanan berbahan aktif the hijau telah menyita perhatian masyarakat. Penyubur rambut berbahan aktif ekstrak teh hijau berbentuk gel belum dijumpai di kalangan masyarakat. Berdasarkan fenomena tersebut, penelitian ini bertujuan mengembangkan formula gel penyubur rambut berbahan aktif ekstrak teh hijau. Penelitian ini dilakukan dengan membuat empat formula, yaitu formula I (carbopol 1%, TEA 0,3%, gliserin 1 %), formula II (CMC Na 3%, gliserin 1%,), formula III (PEG 400 72 %, PEG 4000 8%, gliserin 1%) dan formula IV (carbopol 0,75%, TEA 2%, PEG 400 12 % gliserin 1 %. Masing-masing formula mengandung ekstrak teh hijau dengan kadar 5%, pengawet nipagin 0,1 %, dan natrium metabisulfit 0,1%, sediaan dibuat 100 gram. Keempat  gel yang diperoleh kemudian diuji kualitas sediaannya meliputi uji organoleptis, uji homogenitas, uji pH, uji daya sebar, uji daya lekat, uji daya proteksi, uji iritasi primer, uji aseptabilitas, serta uji aktivitas penyubur rambut. Dari penelitian diketahui bahwa formula gel yang paling optimal adalah formula I yang terdiri dari carbopol 1 %, TEA 0,3 %, dan gliserin 1%. Formula I menunjukkan konsistensi gel yang baik, mempunyai aktivitas penyubur rambut paling tinggi, tidak mengiritasi kulit, serta mempunyai sifat aseptabilitas yang baik.

2016 ◽  
Vol 5 ◽  
Author(s):  
Seung Chik Jwa ◽  
Kohei Ogawa ◽  
Minatsu Kobayashi ◽  
Naho Morisaki ◽  
Haruhiko Sago ◽  
...  

AbstractMaternal vitamin intake during pregnancy is crucial for pregnancy outcomes and the child's subsequent health. However, there are few valid instruments for assessing vitamin intake that address the effects of nausea and vomiting during pregnancy (NVP). This study aimed to investigate the validity of a FFQ concerning vitamin intake during early and late pregnancy with and without NVP. The participants comprised 200 Japanese pregnant women who completed the FFQ and from whom blood samples were taken in early and late pregnancy. Energy-adjusted dietary vitamin intakes (vitamin C, folate, vitamin B6, vitamin B12, vitamin A, vitamin E and vitamin D) from FFQ were compared with their blood concentrations. A subgroup of women with NVP was investigated. In early pregnancy, significant correlations between FFQ and biomarkers were observed for vitamin C (r0·27), folate (r0·18) and vitamin D (r0·26) in women with NVP and for vitamin A (r0·18), vitamin B12(r0·24) and vitamin D (r0·23) in women without NVP. No significant correlations were observed in either group for vitamins B6or E. In late pregnancy, similar significant associations were observed for vitamin C (r0·27), folate (r0·22), vitamin B6(r0·18), vitamin B12(r0·27) and vitamin A (r0·15); coefficients were higher among women without NVP. Our study demonstrates that the FFQ is a useful tool for assessing intake of several important vitamins in early and late pregnancy regardless of NVP status.


2017 ◽  
Vol 2 (2) ◽  
pp. 224
Author(s):  
Yulistia Budianti Soemarie ◽  
Tri Astuti ◽  
Nur Rochmah

Currently, the development of acne drugs (antiacne) use  many natural materials because the natural materials can minimize the side effect if compared with synthetic chemicals drugs. Acne can caused by propionibacterium acnes, staphylococcus epidermis and staphylococcus aureu. One of plants that can be used for acne treatment is leaves of Avocado (Persea americana Mill). The aim of this study was to know whether the ethanol extract of leaves of avocado (Persea americana Mill.) can be made into an ointment preparations that fulfill the requirements. Sample in this research was extract of avocado leaves which used maceration method. The ointment formulations were made into some variation concentrations of PEG 400 and PEG 4000: Formula I (30%:70%); Formula II (50%:50%) and Formula III (70%:30%). The results show that the ointment of avocado leaves which fulfilled the requirements of physical properties is formula III with concentration of PEG 400 70 % and PEG 4000 30 %


2019 ◽  
Author(s):  
Rika Wijayati
Keyword(s):  

Abon yang berbahan dasar nangka muda ini diharapkan dapat dijadikan solusi untuk mengoptimalkan kekayaan alam sekitar. Selain itu abon dari nangka muda ini dapat menjadi alternative bagi para konsumen pencinta abon, tetapi takut akan masalah kesehatan terutama kolestrol. Abon dari nangka muda ini mengandung berbagai jenis gizi yang baik untuk kesehatan manusia, salah satunya mengandung vitamin A, vitamin C dan vitamin B kompleks. Dengan teknik pengolahan yang tepat abon dari nangka muda ini memiliki citra rasa yang tidak kalah enaknya dengan abon sapi.


Author(s):  
Tri Puji Lestari

ABSTRAK Daun Belimbing Wuluh (Averrhoa bilimbi L) memiliki kandungan tanin dan flavonoid. Kandungan Flavonoid dan Tanin yang terdapat dalam belimbing wuluh mampu memberikan efek untuk menyembuhkan kulit yang mengalami kerusakan jaringan sel akibat luka bakar. Ada beberapa cara untuk pemanfaatan Daun Belimbing Wuluh antara lain dengan dibuat dalam sediaan salep. Pada penelitian ini salep dibuat dengan variasi konsentrasi ekstrak daun belimbing wuluh sebesar 10%, 15%, dan 20%  mengguankan basis PEG 4000 dan PEG 400. Ekstrak daun belimbing wuluh diperoleh menggunakan metode maserasi dengan menggunakan etanol 70% sebagai pelarutnya. Salep yang sudah dibuat kemudian dilakukan uji karakteristik meliputi uji organoleptis, homogenitas, daya lekat dan uji daya sebar. Hasil uji organoleptis dan homogenitas di analisa secara deskrisptif kemudian hasil uji daya lekat dan uji daya sebar di analisa dengan menggunakan analisa statistik one-way ANOVA.  Hasil penelitian menunjukan bahwa salep berbentuk semipadat dengan warna hijau muda sampai hijau kehitaman. Hasil uji homogenitas di dapatkan untuk ketiga formula adalah homogen. Nilai daya sebar pada ketiga formula menunjukan perbedaan yang signifikan, pada hasil uji daya lekat dan pH didapatkan tidak ada perbedaan yang signifikan terhadap ketiga formulasi. Dengan demikian perbedaan konsentrasi zat aktif yang digunakan berpengaruh terhadap daya sebar sediaan salep ekstrak daun belimbing wuluh. Kata kunci: Averrhoa bilimbi L; Salep; PEG   ABSTRACT Carambola leaf Wuluh (Averrhoa bilimbi L) contains tannins and flavonoids. The content of flavonoids and tannins contained in starfruit able to give effect to heal skin damaged cell tissue from burns. There were several ways for  utilization  of  Averrhoa  bilimbi  L.  among  others,  made  some  preparations, especially ointment formulation. This study aims to formulate leaf extract ointment preparation starfruit (Averrhoa bilimbi L) with various concentrations of 10%, 15%, and 20% using the PEG 4000 and PEG 400 as a base. Leaf extract obtained from meserasi leaf Averrhoa bilimbi  L  with  70%  ethanol. The ointment that has been made is then subjected to characteristic tests including organoleptic tests, homogeneity, adhesion and spreadability tests. The results of the organoleptic test and homogeneity were analyzed descriptively, then the results of the adhesion test and the spreadability test were analyzed using one-way ANOVA statistical analysis. The results showed that the ointment was semisolid, light green to blackish green. The homogeneity test results obtained for the three formulas are homogeneous. The value of the spreadability of the three formulas showed a significant difference, the results of the adhesion and pH test showed no significant difference between the three formulations. Thus the difference in the concentration of the active substance used affects the spreadability of the starfruit leaf extract ointment. Keywords: Averrhoa bilimbi L; ointment; PEG


2021 ◽  
Vol 903 ◽  
pp. 127-133
Author(s):  
Vadim Myadelets ◽  
Vjaceslavs Lapkovskis ◽  
Andrey V. Kasperovich

In this paper, the influence of the modification method applied to ground vulcanizate (GV) on the properties of elastomeric compositions based on nitrile rubber is discussed. Modified GV has been mixed with the elastomeric composition, which is used for the manufacturing of oil-petroleum-resistant rubber products.The work takes into consideration two types of GV with different chemical nature. The first GV type is rubber crumb produced from end-of-life tires. The second GV type was obtained from rubber wastes based on nitrile rubber. Three methods of the modification are compared in the research: mechanical activation in a planetary ball mill, swelling in a Polyethylene glycol (PEG-400) medium, and the mechano-chemical transformation of GV with PEG-4000. It is shown that depending on the dosage addition of GV modified with PEG-4000 reduce the compression set up for (16.1±0.7%), the strength decreases only by 2.1–8.3%, and the elongation at break increases by 0.8–10.3% compared to rubber without additives.


1997 ◽  
Vol 41 (6) ◽  
pp. 344-352 ◽  
Author(s):  
P. Pfitzenmeyer ◽  
J.C. Guilland ◽  
Ph. d’Athis
Keyword(s):  

Author(s):  
Rosmi Jose ◽  
Venketeswaramurthy N ◽  
Sambath Kumar R

This review describes about the literatures addressing the role of vitamin supplementation in schizophrenia. Evidence is suggesting that vitamin supplementation includes Vitamin A, Vitamin D, Vitamin E, Vitamin B complex, and Vitamin C may be important in treatment. In schizophrenia, patients may have increased level of homocysteine (Hcy), due to the polymorphism in methylenetetrahydrofolate reductase and hypofunction of N-methyl-D-aspartate receptors. The vitamins main effects are reduced the Hcy level and maintain dopamine and serotonin levels. Add-on treatment with high-dose B vitamins including B6, B9, and B12 and also Vitamin D can significantly reduce symptoms of schizophrenia more than standard treatments alone.


2011 ◽  
Vol 106 (5) ◽  
pp. 700-707 ◽  
Author(s):  
Jen-Yin Chen ◽  
Chin-Chen Chu ◽  
Yung-Song Lin ◽  
Edmund Cheng So ◽  
Ja-Ping Shieh ◽  
...  

Postherpetic neuralgia (PHN) is the most common complication of herpes zoster (HZ). The aim of the present study was to compare the nutritional status of PHN patients with that of healthy controls, and then to identify risk factors for PHN using multivariate multiple logistic regressions. In the present cross-sectional study, we prospectively enrolled fifty PHN patients for at least 3 months and fifty healthy controls. We selected nine circulating nutrients including ionised Ca, Zn, retinol, folic acid, vitamin B12, vitamin C, α-tocopherol, γ-tocopherol and lycopene associated with both immunity and the modulation of neuropathic pain, and measured their concentrations in plasma/serum. Concentrations of ionised Ca, Zn, vitamin C and vitamin B12were significantly lower in PHN patients than in controls after excluding those patients receiving supplements since the outbreak of HZ. The prevalence of either mild/marginal or severe deficiencies for any of the nine selected circulating nutrients in PHN patients (92 %) was much higher than that in controls (46 %) (P < 0·001). Lower concentrations of vitamin C ( ≤ 45·0 μmol/l), ionised Ca ( ≤ 1·05 mmol/l) and Zn ( ≤ 0·91 g/l) were found to increase independently the risk of PHN using binary variable (dichotomy) analyses with both PHN patients and controls in a multivariate logistic regression analysis. No significant correlations existed between the risks of PHN and the concentrations of retinol, folic acid, vitamin B12, lycopene or α:γ-tocopherol ratios. Thus, lower concentrations of circulating nutrients, namely vitamin C, ionised Ca or Zn, are probably a risk factor in Taiwanese patients with PHN.


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