scholarly journals Experience on using Resveratrol in the comprehensive treatment of patients with psoriasis

2019 ◽  
pp. 58-64
Author(s):  
Елена Безега ◽  
Ирина Попова ◽  
Екатерина Васильева ◽  
Николай Дудченко ◽  
Алексей Гладков
Keyword(s):  
Antioxidant Properties ◽  
Cell Membrane Permeability ◽  
Erythrocyte Membranes ◽  
Comprehensive Treatment ◽  
Treatment Regimens ◽  
New Methods ◽  
High Level ◽  
The Relationship ◽  
Methods Of Treatment ◽  
Fractional Content

This work is devoted to the search for new methods of treatment because of the high level of the prevalence of psoriasis. This article describes the relationship between the dependence of the clinical picture and lipid peroxi­dation in patients with psoriasis and the advisability of including drugs with antioxidant properties in the treat­ment. LOPs regulate cell proliferation and cell membrane permeability. In patients with psoriasis in the blood se­rum, there is an increase in the level of lipid metabolism products, namely cholesterol, triglycerides and free fatty acids, as well as a change in the ratio of the fractional content of phospholipids in erythrocyte membranes. Therefore, one of the most characteristic manifestations of the activity of the psoriatic process is dyslipidemia. Given the pathogenic mechanisms of the development of this disease and increase effectiveness in complex treatment, it is advisable to include drugs with antioxidant properties. Antioxidants are biological substances that can interact with various forms of free radicals and lead to their inhibition or complete blockage. The study was conducted with the addition of Resveratrol to standard treatment regimens for psoriasis. The scope of labora­tory studies included the diagnosis of changes in a bio­chemical blood test collected on an empty stomach in the morning, namely, to study the content of: total protein, albumin, bilirubin, low and high density lipids, phospho­lipids, cholesterol, alanine aminotransferase, aspartate aminotransferase. After the treatment, the effectiveness of the treatment of complex therapy with the addition of antioxidants has been proved.

Comprehensive treatment of glaucoma (literature review)

2021 ◽  
pp. 81-83
Author(s):  
N.В. Zaynullina ◽  
◽  
E.N. Matyukhina ◽  
Keyword(s):  
Intraocular Pressure ◽  
Acupuncture Therapy ◽  
Cost Effective ◽  
Comprehensive Treatment ◽  
New Methods ◽  
Cost Effective Method ◽  
Ophthalmic Pathology ◽  
Key Word ◽  
Scientific Papers ◽  
Methods Of Treatment

Due to the growing incidence of such ophthalmic pathology as glaucoma, it is necessary to search for new methods of treatment of this disease. One of the non-drug methods of treating glaucoma is reflexology. This type of treatment can be an definitive and cost-effective method used to improve the overall condition. Our review of scientific papers shows that the results of acupuncture therapy in glaucoma patients are ambiguous and contradictory. Therefore, a more detailed study of the effectiveness of acupuncture therapy in glaucoma patients is necessary. Key word: acupuncture, glaucoma, paraorbital points, intraocular pressure.

Hemmkörperentwicklung bei Hämophilie-Patienten nach Präparate wechsel

2012 ◽  
Vol 32 (S 01) ◽  
pp. S39-S42 ◽  
Author(s):  
S. Kocher ◽  
G. Asmelash ◽  
V. Makki ◽  
S. Müller ◽  
S. Krekeler ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Observational Study ◽  
Retrospective Observational Study ◽  
Frequent Change ◽  
Patient Age ◽  
Treatment Regimens ◽  
Patient Âgé ◽  
The Relationship ◽  
Observation Period

SummaryThe retrospective observational study surveys the relationship between development of inhibitors in the treatment of haemophilia patients and risk factors such as changing FVIII products. A total of 119 patients were included in this study, 198 changes of FVIII products were evaluated. Results: During the observation period of 12 months none of the patients developed an inhibitor, which was temporally associated with a change of FVIII products. A frequent change of FVIII products didn’t lead to an increase in inhibitor risk. The change between plasmatic and recombinant preparations could not be confirmed as a risk factor. Furthermore, no correlation between treatment regimens, severity, patient age and comorbidities of the patients could be found.

Academic motivation and professional skills development in the Specialty of Social Sciences and Tourism at a public university [Motivación académica y desarrollo de competencias profesionales en la Especialidad de Ciencias Sociales y Turismo de una universidad pública]

2019 ◽  
Vol 1 (2) ◽  
pp. 96
Author(s):  
Ana Cecilia De Paz Lazaro ◽  
Jessica Luz Palomino Collantes
Keyword(s):  
Social Sciences ◽  
Academic Motivation ◽  
Public University ◽  
Skills Development ◽  
Professional Skills ◽  
Research Results ◽  
Competencias Profesionales ◽  
High Level ◽  
The Relationship

The objective of the research is to determine the relationship between academic motivation and the professional skills development in the specialty of Social Sciences and Tourism. The study is quantitative and the design is non-experimental correlational translational. The results indicate that there is a high level relationship (0.914) between the independent academic motivation variable and the professional competences development in the Specialty of Social Sciences and Tourism. In conclusion, motivation is directly related to the professional skills development in the specialty of Social Sciences and Tourism. The research results conclude that there is a high relationship between the variables.

Boilerplate

2012 ◽  
Author(s):  
Margaret Jane Radin
Keyword(s):  
Economic Efficiency ◽  
Analytical Framework ◽  
Daily Basis ◽  
Regulatory Agencies ◽  
Jury Trial ◽  
Comprehensive Treatment ◽  
New Methods ◽  
And Control ◽  
Fine Print

Boilerplate—the fine-print terms and conditions that we become subject to when we click “I agree” online, rent an apartment, or enter an employment contract, for example—pervades all aspects of our modern lives. On a daily basis, most of us accept boilerplate provisions without realizing that should a dispute arise about a purchased good or service, the nonnegotiable boilerplate terms can deprive us of our right to jury trial and relieve providers of responsibility for harm. Boilerplate is the first comprehensive treatment of the problems posed by the increasing use of these terms, demonstrating how their use has degraded traditional notions of consent, agreement, and contract, and sacrificed core rights whose loss threatens the democratic order. This book examines attempts to justify the use of boilerplate provisions by claiming either that recipients freely consent to them or that economic efficiency demands them, and it finds these justifications wanting. It argues that our courts, legislatures, and regulatory agencies have fallen short in their evaluation and oversight of the use of boilerplate clauses. To improve legal evaluation of boilerplate, the book offers a new analytical framework, one that takes into account the nature of the rights affected, the quality of the recipient's consent, and the extent of the use of these terms. It goes on to offer possibilities for new methods of boilerplate evaluation and control, and concludes by discussing positive steps that NGOs, legislators, regulators, courts, and scholars could take to bring about better practices.

Barriers of physical activity (kinesiophobia) in patients subjected to cardiac rehabilitation

2014 ◽  
Vol 6 (4) ◽  
Author(s):  
Janusz Kocjan ◽  
Andrzej Knapik
Keyword(s):  
Physical Activity ◽  
Cardiac Rehabilitation ◽  
Short Form ◽  
Social Activity ◽  
Self Assessment ◽  
Rehabilitation Process ◽  
Sf 36 ◽  
Polish Version ◽  
High Level ◽  
The Relationship

AbstractBackground: Comprehensive cardiac rehabilitation (CR) is a process designed to restore full physical, psychological and social activity and to reduce cardiovascular risk factors. Fear of movement may contribute to the occurrence and intensification of hypokinesia, and consequently affect the effectiveness of therapy. The aim of the study was to determine the level of barriers of physical activity in patients undergoing cardiac rehabilitation. The relationship between selected determinants (age and health selfassessment) and the kinesiophobia level were also examined.Material/Methods: 115 people aged 40-84 years were examined: 50 females (x = 63.46; SD = 11.19) and 65 males (x = 64.65; SD = 10.59) - patients undergoing cardiac rehabilitation at the Upper-Silesian Medical Centre in Katowice. In the present study, the Polish version of questionnaires: Kinesiophobia Causes Scale (KCS) and Short Form Health Survey (SF-36) were used. Questionnaires were supplemented by authors’ short survey.Results: The patients presented an elevated level of kinesiophobia, both in general as well as in individual components. In women, the kinesiophobia level was higher than in men. The psychological domain was a greater barrier of physical activity than the biological one. Strong, negative correlations of psychological and biological domains of kinesiophobia to physical functioning (SF-36) were noted in women. In the case of men, correlations were weaker, but also statistically significant.Conclusions: 1. Sex differentiates patients in their kinesiophobia level 2. Poor self-assessment of health is associated with a greater intensification of kinesiophobia 3. A high level of kinesiophobia may negatively affect cardiac rehabilitation process

Investigation of Online Learning Satisfaction During COVID 19: In Relation to Academic Achievement

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Abdul Basith ◽  
Rosmaiyadi Rosmaiyadi ◽  
Susan Neni Triani ◽  
Fitri Fitri
Keyword(s):  
Academic Achievement ◽  
Online Learning ◽  
Random Sampling ◽  
Sampling Technique ◽  
Simple Random Sampling ◽  
Research Data ◽  
Student Academic Achievement ◽  
Learning Satisfaction ◽  
High Level ◽  
The Relationship

The aim of this research is; 1) investigating the level of online learning satisfaction among students during COVID 19; 2) analyzing the influence of differences in gender, years of study, major in determining online learning satisfaction among students during COVID 19; 3) to analyze the relationship between online learning satisfaction and student academic achievement during COVID 19. The population was 656 students at STKIP Singkawang, and then a sample of 357 students (87 males and 270 females) was taken using a simple random sampling technique. The instrument in this study was adapted from Aman's Satisfaction instrument, which was then used to collect research data. Data analysis using SPSS with descriptive statistical techniques, MANOVA, and correlation. The results showed that online learning satisfaction was at a high level, meaning that students were satisfied with the online learning that had been implemented. The major differences have a significant effect on determining online learning satisfaction. Intercorrelation shows that there is a significant relationship on each indicator of online learning satisfaction with academic achievement, meaning that the higher the satisfaction felt by students in online learning, the student's academic achievement will increase.

CHALLENGES OF INTERPRETATION OF GENETIC TEST RESULTS ON THE EXAMPLE OF STUDY OF ENDURANCE

2020 ◽  
Vol 8 (1) ◽  
pp. 75-82
Author(s):  
Elmira Shamsuvaleeva ◽  
Anastasiya Nevmyvaka ◽  
Andrey Nazarenko
Keyword(s):  
Sport Activity ◽  
Computerized Testing ◽  
Daily Routine ◽  
Modern Approach ◽  
Functional Studies ◽  
Sport Training ◽  
Genetic Test Results ◽  
High Level ◽  
Biomedical Education ◽  
The Relationship

The purpose of the research is to study the possibility of predicting the development of aerobic endurance of athletes through a comparative analysis of the outcomes of genetic and computerized testing. Methods and organization of the research. In our research, we used scientific and methodological literature, as well as the outcomes of competitive activity and genetic analysis of a particular athlete. The total number of survey respondents was 158 people including athletes (n = 85) and coaches (n = 73). Results and discussion. Some authors find the relationship between the ability to develop and manifest endurance and the presence of the appropriate alleles of genes: ACE I, ACNT X, ACNT3 (RX, XX), ADRA2A, AMPDI C, PGC1A Gly, NFATC4, UCP2. Most studies reveal the relationship between the ACE gene and endurance supported by the I allele. Genetic foresight of the possibility of developing aerobic endurance of athletes can become the framework for the application of an individual approach in sport training, and contribute to the development of techniques aimed at the refinement of physical qualities. The modern approach to the coaching and competitive activities of athletes should include both genetic and functional studies of the human body. Conclusion. Sport forecast cannot be based solely on genetic testing results. The presence of polymorphisms in one or more genes associated with sport activity is the platform for good performance in a particular sport, but the actual manifestation of genetic predisposition depends on many factors. These factors include nutrition, daily routine and competent organization of the training process, which requires a high level of theoretical and practical competency of coaches in the field of biomedical education.

Machine learning for rediscovering revolutionary ideas of the past

2021 ◽  
pp. 105971232098304
Author(s):  
R Alexander Bentley ◽  
Joshua Borycz ◽  
Simon Carrignon ◽  
Damian J Ruck ◽  
Michael J O’Brien
Keyword(s):  
Language Processing ◽  
Scientific Progress ◽  
Phylogenetic Inference ◽  
The Past ◽  
New Methods ◽  
Inherent Nature ◽  
Social Learning Processes ◽  
High Level ◽  
Scientific Ideas ◽  
Revolutionary Science

The explosion of online knowledge has made knowledge, paradoxically, difficult to find. A web or journal search might retrieve thousands of articles, ranked in a manner that is biased by, for example, popularity or eigenvalue centrality rather than by informed relevance to the complex query. With hundreds of thousands of articles published each year, the dense, tangled thicket of knowledge grows even more entwined. Although natural language processing and new methods of generating knowledge graphs can extract increasingly high-level interpretations from research articles, the results are inevitably biased toward recent, popular, and/or prestigious sources. This is a result of the inherent nature of human social-learning processes. To preserve and even rediscover lost scientific ideas, we employ the theory that scientific progress is punctuated by means of inspired, revolutionary ideas at the origin of new paradigms. Using a brief case example, we suggest how phylogenetic inference might be used to rediscover potentially useful lost discoveries, as a way in which machines could help drive revolutionary science.

scholarly journals The relationship between time to a high COVID-19 response level and timing of peak daily incidence: an analysis of governments’ Stringency Index from 148 countries

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Yan Ma ◽  
Shiva Raj Mishra ◽  
Xi-Kun Han ◽  
Dong-Shan Zhu
Keyword(s):  
Standard Error ◽  
Daily Basis ◽  
Linear Regression Models ◽  
Response Level ◽  
Peak Number ◽  
Epidemic Curve ◽  
Government Response ◽  
Early Arrival ◽  
High Level ◽  
The Relationship

Abstract Background The transmission dynamics and severity of coronavirus disease 2019 (COVID-19) pandemic is different across countries or regions. Differences in governments’ policy responses may explain some of these differences. We aimed to compare worldwide government responses to the spread of COVID-19, to examine the relationship between response level, response timing and the epidemic trajectory. Methods Free publicly-accessible data collected by the Coronavirus Government Response Tracker (OxCGRT) were used. Nine sub-indicators reflecting government response from 148 countries were collected systematically from January 1 to May 1, 2020. The sub-indicators were scored and were aggregated into a common Stringency Index (SI, a value between 0 and 100) that reflects the overall stringency of the government’s response in a daily basis. Group-based trajectory modelling method was used to identify trajectories of SI. Multivariable linear regression models were used to analyse the association between time to reach a high-level SI and time to the peak number of daily new cases. Results Our results identified four trajectories of response in the spread of COVID-19 based on when the response was initiated: before January 13, from January 13 to February 12, from February 12 to March 11, and the last stage—from March 11 (the day WHO declared a pandemic of COVID-19) on going. Governments’ responses were upgraded with further spread of COVID-19 but varied substantially across countries. After the adjustment of SI level, geographical region and initiation stages, each day earlier to a high SI level (SI > 80) from the start of response was associated with 0.44 (standard error: 0.08, P < 0.001, R2 = 0.65) days earlier to the peak number of daily new case. Also, each day earlier to a high SI level from the date of first reported case was associated with 0.65 (standard error: 0.08, P < 0.001, R2 = 0.42) days earlier to the peak number of daily new case. Conclusions Early start of a high-level response to COVID-19 is associated with early arrival of the peak number of daily new cases. This may help to reduce the delays in flattening the epidemic curve to the low spread level. Graphic abstract

scholarly journals Report on the 18th International Symposium on Geo-disaster Reduction and the 4th Gu Dezhen Lecture, 20–22 November 2020, Beijing, China

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Shengwen Qi ◽  
Ning Liang ◽  
Kongming Yan ◽  
Zili Dai ◽  
Fawu Wang
Keyword(s):  
International Symposium ◽  
Disaster Reduction ◽  
High Level ◽  
The Relationship ◽  
Beijing China

AbstractThe 18th International Symposium on Geo-disaster Reduction (ISGdR) was held on 20–22 November in Beijing, China, focusing on the theme of “Improving the Relationship between Geoenvironment and Society”. In this symposium, a high-level Gu Dezhen Lecture and a number of keynote and invited lectures provided a platform for scientists, industrial professionals and students to share their researches and exchange novel ideas on geo-disaster reduction in a hybrid way of offline and online.

Sign in / Sign up

Export Citation Format

Share Document