Biochemical Composition And Medical Value Of Pharmacy Chamomile

Author(s):  
Yuldashev Nasirdjan ◽  
◽  
Tuhtaeva Feruza ◽  

Chamomile has been used in scientific and folk medicine since ancient times and is still widely used in medicine due to its high medicinal properties. The beneficial effects of the flavonoids, essential oils and other biochemicals contained in it prevent and fight many diseases in the body thanks to its positive effects.

2017 ◽  
pp. 151-161
Author(s):  
Jasmina Cilerdzic ◽  
Mirjana Stajic ◽  
Jelena Vukojevic

Ganoderma lucidum has a long tradition of use in folk medicine of the Far East, which is documented in the oldest Chinese pharmacopoeia, written in the first century B.C, declaring it a superior medicine. The healing properties of G. lucidum reflected on folk names such as: Reishi, Mannentake, Ling Zhi etc., which mean ?herb of spiritual power?, ?mushroom of immortality? or ?10,000-year mushroom?, respectively. It has been known, for thousands of years, that this species extends life span, increases youthful vigour and vitality and it was used in the treatments of hepatitis, kidneys? disease, hypertension, arthritis, asthma, bronchitis, arteriosclerosis, ulcers and various types of cancer. However, Western civilisation did not discover its healing properties until the 20th century. Modern scientific researches and numerous clinical trails, conducted in recent decades, have confirmed the ancient knowledge of Eastern nations and given them a scientific basis. These studies have demonstrated many biological activities of G. lucidum extracts and compounds, including: immunomodulating, antioxidative, cytotoxic, hypoglycaemic, anti-inflammatory, antiallergic, antimicrobial, etc. It has been reported that its extracts play important role in detoxification of the body and protecton of the liver, as well as in reducing cardiovascular problems, stress and anxiety. However, its most important effect is undoubtedly immunostimulating one as it is the basis of many other positive effects. The Japanese government introduced G. lucidum on the official list of auxiliary agents for the treatments of various cancers, Alzheimer?s disease, diabetes and chronic bronchitis. Many chemical components have been isolated from G. lucidum, but polysaccharides and terpenoids are the main carriers of its bioactivities.


2020 ◽  
Vol 9 (2) ◽  
pp. 71-78
Author(s):  
Katarina Stepić ◽  
Danijela Kostić ◽  
Jovana Ickovski ◽  
Ivan Palić ◽  
Gordana Stojanović

Since the ancient times, people have used essential oils as a cure because they have noticed their beneficial effects on the human mind and body. What they did not know was how these essential oils actually affected the human body, as well as exactly what component or more of them were responsible for the activity of a particular oil. Therefore, a lot of attention has recently been paid to the detailed identification of the constituents of essential oil and determination of the biological activity of the essential oil itself, as well as of those identified constituents. The aim of this paper is to systematize the most used, most accessible and easily feasible techniques for determining the biological activity of essential oils. For this purpose, the following tests are mentioned in this paper: fumigation, insecticidal, pediculi-cidal, nematicidal, larvicidal, ovicidal, cytotoxic and antinociception bioassay.


2021 ◽  
Vol 2021 ◽  
pp. 1-18
Author(s):  
Can Jin ◽  
Peipei Wu ◽  
Linli Li ◽  
Wenrong Xu ◽  
Hui Qian

Exosomes are nanometer-sized small EVs coated with bilayer structure, which are released by prokaryotic and eukaryotic cells. Exosomes are rich in a variety of biologically active substances, such as proteins, nucleotides, and lipids. Exosomes are widely present in various body fluids and cell culture supernatants, and it mediates the physiological and pathological processes of the body through the shuttle of these active ingredients to target cells. In recent years, studies have shown that exosomes from a variety of cell sources can play a beneficial role in acute and chronic kidney disease. In particular, exosomes derived from mesenchymal stem cells have significant curative effects on the prevention and treatment of kidney disease in preclinical trials. Besides, some encapsulated substances are demonstrated to exert beneficial effects on various diseases, so they have attracted much attention. In addition, exosomes have extensive sources, stable biological activity, and good biocompatibility and are easy to store and transport; these advantages endow exosomes with superior diagnostic value. With the rapid development of liquid biopsy technology related to exosomes, the application of exosomes in the rapid diagnosis of kidney disease has become more prominent. In this review, the latest development of exosomes, including the biosynthesis process, the isolation and identification methods of exosomes are systematically summarized. The utilization of exosomes in diagnosis and their positive effects in the repair of kidney dysfunction are discussed, along with the specific mechanisms. This review is expected to be helpful for relevant studies and to provide insight into future applications in clinical practice.


2018 ◽  
Vol 3 ◽  
pp. 8-75 ◽  
Author(s):  
Feriedoon Shahidi ◽  
Abul Hossain

Spices have broadly been used as food flavoring and folk medicine since ancient times. Numerous phytochemicals have been identified in spices, namely thymol (ajowan and thyme), anethole (aniseed), piperine (black pepper), capsaicin (capsicum), cinnamaldehyde (cinnamon), eugenol (clove), linalool (coriander), sabinene (curry leaf), limonene (dill seed), estragole (fennel seed), allicin (garlic), gingerol (ginger), safranal (saffron), and curcumin (turmeric), among others. The antioxidants in spices are very effective and also render anti-mutagenic, cardioprotective, anti-inflammatory, and anti-cancer properties. Apart from their antioxidant efficacy, spices, particularly their essential oils possess strong antimicrobial activity against bacteria, fungi, yeasts, and microbial toxins synthesis. In this contribution, a summary of the most relevant and recent findings on phytochemical composition and antioxidant properties of spices has been compiled and discussed. The content of phenolic acids, flavonoids, tannins, glycosides, steroids, and terpenoids in different spices are summarized. In addition, the beneficial effects of spices in food preservation and in health promotion and disease risk reduction are briefly described.


Author(s):  
Flávia Fernanda Alves da Silva ◽  
Cassia Cristina Fernandes ◽  
Gabriel Almeida de Oliveira ◽  
Ana Carolina Bolela Bovo Candido ◽  
Lizandra Guidi Magalhães ◽  
...  

In Brazilian folk medicine, Murraya paniculata has been used for treating intestine disorders, rheumatism and cough. This paper aims to investigate the in vitro antileishmanial and antioxidant activities of essential oils (EO) from M. paniculata leaves and fruits (ripe and unripe ones). Natural antioxidants may be very beneficial to improve quality of life, since they are capable of protecting the body against damage caused by free radicals and, consequently, either preventing or postponing many diseases from starting their cycles. One of the techniques which has been widely used for detecting antioxidant compounds is the method based on the elimination of the stable free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH•). It has been considered easy, precise, fast, simple, economical and appropriate to determine antioxidant activity of pure substances and complex mixtures, such as EO. Thus, antioxidant potential of EO was evaluated by using the method of the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH•). EO from M. paniculata leaves and fruits exhibited weak potential, since EC50 values were above 700 µg/mL. Several reports have stated that volatile oils from plants show promising leishmanicidal activity against promastigote forms of Leishmania amazonensis; in relation to this activity, leaf oil was highly active (IC50 = 7.33±2.07 µg/mL) while ripe and unripe fruit oils were active, with values of IC50 = 30.77±2.07 µg/mL and 13.04±1.64 µg/mL, respectively. Both GC-FID and GC-MS analyses revealed that the major components determined in EO from M. paniculata were sesquithujene (25.0%), trans-β-caryophyllene (23.8%), α-zingiberene (21.0%), α-ylangene (13.3%), germacrene D (13.1%), α-copaene (12.7%), and β-cubebene (10.2%). In vitro antileishmanial and antioxidant activities of EO from M. paniculata have also been described for the first time.


2018 ◽  
Vol 10 (Especial 5) ◽  
pp. 29-34
Author(s):  
Alessandra Serafim Oliveira ◽  
Marcos Alberto Zocoler

Neurocosmetics are cosmetics that act in the body in a similar way to endogenous neuromediators, exerting beneficial effects on the health and beauty of skin, hair and cutaneous attachments. Essential oils of jasmine and lavender, used in neurocosmetics, act on the receptors of the skin acting in the emotional state, alleviating the symptoms of anxiety, stress, depression, nervous tension and insomnia. Two formulations have been developed: Body Bath Oil and Moisturizing Cream containing essential oils of jasmine and lavender. A sample of 20 people (men and women), who duly approved the inclusion criteria of the research: Accept participate in the 30 Colloquium Vitae, vol. 10, n. Especial 5, Jul–Dez, 2018, p.29-34. ISSN: 1984-6436. DOI: 10.5747/cv.2018.v10.nesp5.000329 research signing the Free and Informed Consent Form. Judges will use neurocosmetics for 14 days. The anti-stress efficacy of each product was evaluated through structured questionnaires. It was also evaluated the sensorial of the cosmetic products after its use. The attributes that were evaluated in this experiment will be: appearance of the product, ease of spreading, degree of hydration and fragrance, after its use. The skin of the judges was analyzed using the Skin Analyzer Pen SK-02. The data collected were evaluated through analysis of variance ANOVA, where the results were considered significant when the probability was less than 5% by the Tukey test. The twenty volunteers who participated in this research, who used body oil and moisturizer both containing the essential oils of lavender and jasmine, reported that these products were effective in reducing the level of stress. The sensations observed after the application of the body oil and moisturizer on the skin were refreshment, decreased nervous tension, tranquility, comfort and softness. Through the statistical analysis it was verified that there were no significant differences of acceptance among the formulations in the attributes: ease of spread, sensation in the skin and intention to buy. So all volunteers reported that they would buy the products if they were marketed


Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3155
Author(s):  
Karin Lunz ◽  
Iris Stappen

Since ancient times, plant roots have been widely used in traditional medicine for treating various ailments and diseases due to their beneficial effects. A large number of studies have demonstrated that—besides their aromatic properties—their biological activity can often be attributed to volatile constituents. This review provides a comprehensive overview of investigations into the chemical composition of essential oils and volatile components obtained from selected aromatic roots, including Angelica archangelica, Armoracia rusticana, Carlina sp., Chrysopogon zizanioides, Coleus forskohlii, Inula helenium, Sassafras albidum, Saussurea costus, and Valeriana officinalis. Additionally, their most important associated biological impacts are reported, such as anticarcinogenic, antimicrobial, antioxidant, pesticidal, and other miscellaneous properties. Various literature and electronic databases—including PubMed, ScienceDirect, Springer, Scopus, Google Scholar, and Wiley—were screened and data was obtained accordingly. The results indicate the promising properties of root-essential oils and their potential as a source for natural biologically active products for flavor, pharmaceutical, agricultural, and fragrance industries. However, more research is required to further establish the mechanism of action mediating these bioactivities as well as essential oil standardization because the chemical composition often strongly varies depending on external factors.


2018 ◽  
Vol 13 (6) ◽  
pp. 1934578X1801300 ◽  
Author(s):  
Olivera Politeo ◽  
Ana Maravić ◽  
Franko Burčul ◽  
Ivana Carev ◽  
Jure Kamenjarin

Members of the Cistus genus have been traditionally used in folk medicine since ancient times as a remedy for various infections and diseases. In this paper essential oils of four wild growing Cistus species in Croatia were examined for their chemical composition and antimicrobial activity against both ATCC and multiple-resistant clinical strains of opportunistic pathogens associated with skin, nail, gastrointestinal, bloodstream and respiratory infections. The results showed that C. villosus and C. salviifolius essential oils have nonterpene compounds as dominant ones, particularly nonterpene acids and derivatives, while C. creticus and C. monspeliensis essential oils have labdane-type diterpene compounds as dominant ones. Tested Cistus oils have a broad spectrum of antimicrobial activities which are dose dependent. C. salviifolius and C. creticus oils were found to be the most potent ones, particularly against leading skin pathogens such as Staphylococcus aureus, Acinetobacter baumannii and Candida albicans. The data presented here presented evidence for biological and aromatical potential of the Cistus essential oils for their further use in traditional medicine.


Plants ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. 959
Author(s):  
Michele Zaccai ◽  
Ludmila Yarmolinsky ◽  
Boris Khalfin ◽  
Arie Budovsky ◽  
Jonathan Gorelick ◽  
...  

Lilium candidum L., known as Madonna, meadow, or white lily, is a bulbous plant from the Liliaceae family, originating in the Middle East. L. candidum has been abundantly used in folk medicine since ancient times to relieve a variety of ailments, including age-related diseases, burns, ulcers, and coughs. The aim of this article is to investigate the anti-inflammatory and anti-diabetic activities of L. candidum extracts and its active phytochemicals. Some active volatile phytochemicals were identified using gas chromatography–mass spectrometry (GC-MS) analysis. Significant (p < 0.001) anti-diabetic properties of the extracts kaempferol, linalool, citronellal, and humulene were demonstrated by an elevation in glucose uptake by adipocytes. The significant (p < 0.01) effect of the plant extracts kaempferol, citronellal, and humulene on the secretion of pro-inflammatory cytokines interleukin 6 (IL-6) and interleukin 8 (IL-8) was demonstrated using enzyme-linked immunosorbent assay. Altogether, L. candidum and its rich collection of phytochemicals hold promising medicinal potential, and further investigations of its therapeutic prospects are encouraged.


AYUSHDHARA ◽  
2021 ◽  
pp. 3371-3376
Author(s):  
Rita Kumari

Strychnous nuxvomica Linn, known as Kuchala in Ayurveda is a well known poisonous herb that consists of multiple health benefits in Indian system of medicine. In Ayurveda, it is said as Upavisha and used as a popular folk medicine from ancient times. This Kuchala is still being used in rural India in the medicinal form. Strychnine is a main contain of Kuchala which was first used in 1540 for the purpose of medicine and continued to be used in many stimulants, tonics and cathartics. It includes constituents like alkaloids with flavonoids, iridoids and phenolic glycosides. Research studies have reported its anti-allergic, anti-inflammatory, antimicrobial, anticancer, antipyretic, gastroprotective, antidiabetic, antialcoholic, hepatoprotective, antioxidant, antinociceptive, anti-snake venom and neuropharmacological properties. Though considered as an extremely poisonous plant, but has enormous medicinal properties.


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