Herbal Products for Management of COVID- 19

2022 ◽  
pp. 242-252
Author(s):  
Simran Jeet Kaur

COVID-19 is a human-infectious virus. The respiratory system is the primary target of the coronavirus, but it can also harm cardiac tissues and gastrointestinal organs. Many frequent circumstances, such as the medication's or medicine's purpose, the dosage/potency of the drug, and the patient's condition, can place patients in grave danger. Several cures have been reported using a variety of therapy methods. Among the various treatments, natural and synthetic medicines are the most commonly documented. Some herbal medicines, such as Tribulusterrestris, Withaniasomnifera, Curcuma longa, Ocimum sanctum, and Phyllanthusemblica, have powerful antiviral (AntiCOV-19) properties against novel coronavirus, heralding the start of a new era in herbal therapy.

Author(s):  
Sonali S Gadge

The COVID-19 has spread all over the world and there is no single drug or medicine for the prevention and the treatment of this deadly disease. One can get prevention from this disease by boosting the immune system. Persons with weak immune system e.g. children, elder patients or patients with preexisting diseases affect rapidly due to coronavirus. This novel coronavirus attacks mainly on the person immunity. For the centuries the herbal medicinal plants have many beneficial effects against deadly viruses. Herbal medicines provide a rich resource for new antiviral drug development. These natural agents interact with the life cycle of virus such as virus entry, replication, assembly and release. In this review, the importance, immunomodulator, antiviral and pharmacological activities of some medicinal plants, namely, Allium Sativum, Zingiber Officinalis, Cinnamomum zeylanicum, Curcuma longa, Ocimum sanctum, Glycyrrhiza glabra, Ginseng, Black pepper, Emblica officinalis, Withania somnifera, Tinospora cordifolia, Echinacea purpurea, Azadirachta indica, Piper betel, Eugenia caryophyllata, Cinchona calisaya, Nigella sativa, Cuminum cyminum are highlighted. These medicinal plants have many phytoconstituents like alkaloids, glycosides, terpenoids, flavonoids, lactones, polysaccharides, volatile oils, tannins, resins, etc which are helpful for boosting immunity and will help in the prevention and in the management of COVID-19. Several types of research attempted to use herbal medicines against COVID-19.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 734-738
Author(s):  
Prashant Bhokardankar ◽  
Bharat Rathi ◽  
Mujahid Khan ◽  
Renu Rathi

COVID- 19 has created a lot of hazardous health issues worldwide. Research fraternity around the world is trying to find out vaccine or medicines against the virus. In this pandemic situation, there is a need for remedies to boost the immunity to fight against the virus. Ayurveda treatises have described several herbal drugs which are used as home remedies and are said to be effective against all microorganisms and effective in boosting immunity. Home remedies can be played a vital role as immunomodulant. Hence in this paper, an attempt is made to review such home remedies and identify its efficacy on various conditions. The relevant references were searched on the internet to find out the scientific data available on home remedies. Fumigation, Rasayan drugs, a decoction of herbal medicines found more useful. Tinospra cordifolia, Glycyrrhiza glabra, Ocimum sanctum, Withania somnifera, Curcuma longa are most decorated single herbal drugs used as home remedies for boosting the immunity. Considering the global disease burden caused by COVID-19, there is an urgent need to explore and widened the use of home remedies to fight against COVID-19 menace effectively.


Abstract-Medicinal plants have been used for centuriesandhavebecomepartofcomplementary medicine worldwide because of their health benefits. Some plants used directly in the treatment and prevention of infectious diseases or indirectly by stimulating the immune system. In recent years there is a great demand throughout the world to use herbal products in healthcare system. Plant materials and their products are becoming popular because of their widebiological activities. Standardization of herbal products is essential for their acceptance as remedies for various diseases and ailments. Marker based standardization is one of the widely accepted methods which is based on the analysis of phytochemical markers using HPTLC, HPLC etc.Identificationofmajoranduniquecompoundsinherbsasmarkersanddevelopment of analytical methodologies for monitoring them are the key steps involved in markerbasedstandardization.Markercompounds are chemically defined constituents of the herbal drug with or without therapeutic activity and can be used for the quality assurance of finished product. In nature, there are various medicinal plants which are used as immunomodulator agents. In this paper we standardize the phytomarkers of some selected plants which are very essential for our daily life.


Author(s):  
Rajeshwar Verma ◽  
Shubham Bhardwaj ◽  
Jyoti Gupta

As we know traditional herbal medicines have been widely used around the world since the ancient times but most of the traditional herbal drugs and their extracts despite of their impressive in-vitro findings demonstrate less or negligible in-vivo activity due to their poor lipid solubility or improper molecular size, resulting in poor absorption and hence poor bioavailability. Poor bioavailability increases system clearance requiring repeated administration or higher dose, which makes the drug as a poor candidate for therapeutic use. Nanotechnology is bringing a new aspect in the field of scientific and technology and its application in healthcare that lead to development of novel drug delivery systems. Drug delivery system for herbal formulations based on applicative, nanotechnology has a potential future for enhancing the product efficacy and overcoming problem of slow or less absorption; associated with the herbal drugs. The marketed nano herbal products are Aegis. Lifepak Nano, Nano phyto proflex, Nano garcinia raspberry, Nano green coffee, Nano D3. Curcuma longa, Gymnema sylvestre, salvia miltiorrhiza, proteins and many more. Hence nano herbal drugs has become the broad view of new nanotech era for better and safer health care.


2021 ◽  
Vol 12 (1) ◽  
pp. 1-6
Author(s):  
Muralidass S D ◽  
Shree Devi M S

In a very short time, the Coronavirus disease (COVID-19) caused by the SARS-CoV-2 virus, has become a global pandemic. It has infected about 29,155,581 patients and brought forth death rate about 926,544 among 216 countries as recorded by World Health Organization on 15th September 2020. At present, there is no specific and direct treatment or vaccine for this infectious disease. No therapeutic options available to cure the infection in till date which increases the mortality rate across the countries. Currently there is no antiviral treatments have been approved, several approaches have been proposed in western medicine, Chinese medicine, CAM, AYUSH and other systems. Siddha Herbal medicines are achieving high attention because of the extensive therapeutics like potent anti-microbial, immunomodulatory, anti-inflammatory, and antioxidant properties. Ministry of AYUSH, Govt. of India recommended 12 Siddha herbals (Inji – Zingiber officinale, Thulasi – Ocimum sanctum, Milaku – Piper nigrum, Karunjeeragam – Nigella sativa, Keezhanelli – Phyllanthus niruri, Adhimathuram – Glycyrrhiza glabra, Vellaippoondu – Allium sativum, Citramutti – Sida cardifolia, Seenthil – Tinospora cordifolia, Manjal – Curcuma longa, Elumitchai – Citrus lemon and Vembu – Azadirachta indica) for the prevention by enhancing immunity as well as for the management of this infectious disease in its recent official publication ‘Guidelines for Siddha Practitioners for COVID 19’. This is the common advisory and the anti-viral activity of these herbals against COVID 19 is not established yet. The current situation demands proper herbal drug utilization to prepare the population immunity to fight against the infection. The present review spotlight on the literature review and the review of pharmacological actions of these herbals.


2020 ◽  
Vol 10 (2) ◽  
pp. e18-e18
Author(s):  
Audrey Tolouian ◽  
Maryam Khosravian ◽  
Hedieh Ragati Haghi ◽  
Alireza Bolourian ◽  
Zahra Mojtahedi ◽  
...  

Coronavirus disease 2019 (COVID-19), caused by a novel coronavirus, started in livestock within the markets of Wuhan, China and was consequently spread around the world. The virus has been rapidly spread worldwide due to the outbreak. COVID-19 is the third serious coronavirus outbreak in less than 20 years after Severe Acute Respiratory Syndrome (SARS) in 2003 and Middle East Respiratory Syndrome (MERS) in 2012. The novel virus has a nucleotide identity closer to that of the SARS coronavirus than that of the MERS coronavirus. Since there is still no vaccine, the main ways to improve personal immunity against this disease are prophylactic care and self-resistance including an increased personal hygiene, a healthy lifestyle, an adequate nutritional intake, a sufficient rest, and wearing medical masks and increasing time spent in well ventilated areas. There is a need for novel antivirals that are highly efficient and economical for the management and control of viral infections when vaccines and standard therapies are absent. Herbal medicines and purified natural products have the potential to offer some measure of resistance as the development of novel antiviral drugs continues. In this review, we evaluated 41 articles related to herbal products which seemed to be effective in the prevention or treatment of COVID-19.


Author(s):  
Gyanendra Mohapatra ◽  
Biswa Mohan Sahoo ◽  
Bimalendu Chowdhury ◽  
J. Sruti ◽  
Rabi Narayan Rana ◽  
...  

: The immune system involves both active and passive immunization. The antibodies are devloped against the antigens during active immunization and are permanently stored. But, in case of passive immunization, the antibodies are exposed to the same antigens in every person who are already infected. In order to enhance the immune systems i.e. innate and adaptive immune responses, herbal plants are used as immune booster. Some of the herbal plants have been proved clinically to enhance the immunity that include Morniga oleifera (Drumstick), Azadirachta indica (Neem), Ocimum sanctum (Tulsi), Withania somnifera (Aswagandha), Zingiber officinale (Ginger), Allium sativum (Garlic), Curcuma longa (Turmeric), Emblica officinalis (Amla) etc. Compared to synthetic drugs, the herbal drugs have fewer or less side effects and stimulate the immune system to defend against various foreign pathogens. Even though, herbal medicines are usually considered as safe and effective therapy, but it is clinically proved that if a drug is effective, it would have some side effects. But, sometimes the antioxidant property of herbal medicines is helpful to reduce the toxicities produced by any toxic substances or any drugs. This review aims to encourage the study of various herbal constituents and their role in the treatment of different types of viral infections.


2018 ◽  
Vol 159 (18) ◽  
pp. 703-708
Author(s):  
Gábor Vasas

Abstract: More than 90% of herbal products and herbal medicines have been derived from higher plants recently, but due to independent circumstances, several photosynthetic microalgal species are in focus in this point of view. In the last 50 years, many carbohydrate-, peptide-, terpenoid-, alkaloid- and phenol-type components were described from algae because of the developing structural determination and analytical methods, algae mass production and also artificial algae technologies. At the same time, based partly on traditional causes and partly on the clinical and preclinical data of today, some dried products of algae are directly used as food supplements. Hereinafter, the historical background, economic significance and metabolic background of the mostly used microalgal species will be reviewed. The diverse metabolite production of these organisms will be demonstrated by some molecules with special bioactivity. Several preclinical and clinical studies will be described relating to the microalgal species Spirulina sp., Chlorella sp., Haematococcus sp. and Dunaliella sp. Orv Hetil. 2018; 159(18): 703–708.


2018 ◽  
Vol 21 (3) ◽  
pp. 161-174 ◽  
Author(s):  
Shanoo Suroowan ◽  
Fawzi Mahomoodally

Background: Common auto-inflammatory disorders (CAIDs) constitute a wide array of ailments ranging from acute allergies to chronic conditions. Globally, CAIDs remain one of the leading causes of disability and morbidity. Despite playing a leading therapeutic role, the vast profusion of anti-inflammatory synthetic agents have not been able to fully resolve a panoply of CAIDs. Additionally, contemporary synthetic therapy approaches remain bounded by a wide array of limitations essentially being adverse effects and unaffordable costs. In this advent, the use of herbal products provides an interesting avenue to explore in view of developing such treatment regimens. Objective: This review article endeavors to highlight potential herbal products and isolated phytochemicals which can be of benefit in the prophylaxis, management, and treatment alongside avoiding the relapse of CAIDs. Conclusion: This review article has highlighted that herbals, herbal products, and isolated metabolites hold a huge potential in the prophylaxis, management, and treatment of CAIDs. Herbals can act on various targets involved in the pathogenesis of inflammatory disorders. In addition, novel approaches for the management of CAIDs are numerous. Indeed, nanoparticles loaded with phytochemicals have been developed to specifically target the colon for IBD treatment. In silico approaches using herbals also offer unlimited avenues to decipher new pharmacophores. Investigating the potential of polyherbal formulations is another unique approach which can be investigated. Given the inefficacy of conventional medicines, the concomitant use of conventional and herbal medicines can also be explored.


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