scholarly journals Is instant porridge with a high calcium content based on Moringa oleifera as an alternative baby food to prevent stunting in Indonesia?

2021 ◽  
Vol 10 (2) ◽  
Author(s):  
Septa Katmawanti ◽  
Supriyadi Supriyadi ◽  
Fariha Mariroh
Keyword(s):  
Standard Deviation ◽  
Breast Milk ◽  
Moringa Oleifera ◽  
Calcium Content ◽  
P Value ◽  
Organoleptic Evaluation ◽  
High Calcium ◽  
Evaluation Panel ◽  
Statistical Results ◽  
Height For Age

Background: According to WHO, stunting is a state of height-for-age index below minus two standard deviation. However, the condition could be prevented by giving suitable complementary food to babies and toddlers. Moringa leaves are rich in vitamins A, C, B6, as well as calcium, potassium, iron, as well as protein, and are therefore used as complementary foods for breast milk, in baby feeding.Design and Methods: Instant porridge was developed using three formulas. Each formula comprised Moringa leaf flour (5, 6 and 7 grams each) combined with 30 grams of oatmeal powder, 40 grams of powdered formula, 10grams of refined sugar, and 5 grams of banana flour.Results: Based on the organoleptic test, Formula 3 (created with 5 grams of Moringa leaf flour) was discovered to be the best. The organoleptic evaluation panel consisted of 3 trained and 30 untrained participants, while the statistical results showed the parameters of colour, texture, and taste, have no significant effect on panellists’ acceptance.Conclusions: The flavour parameter has a significant effect on panellists’ acceptance, with a p-value <0.05.

scholarly journals Pengaruh Metode SPEOS (Stimulasi Pijat Endorfin Oksitosin Suggestif) Terhadap Produksi ASI Pada Ibu Nifas

2021 ◽  
Vol 3 (1) ◽  
pp. 18
Author(s):  
Elisa Elisa ◽  
Latifah Lely Septiariani ◽  
Kurniati Puji Lestari
Keyword(s):  
Standard Deviation ◽  
Breast Milk ◽  
Milk Production ◽  
Sampling Technique ◽  
Test Sample ◽  
Maternity Hospital ◽  
P Value ◽  
Central Java ◽  
Breast Milk Production ◽  
Post Test

Health profile of Semarang in 2018, the exclusive feeding of the exclusive breast milk in the age of 0-6 months of 65.57%. It’s still far from Central Java target of 80%. This problem of breastfeeding influenced by reduced stimulation of oxytocin hormones, while physical and psychological changes can affect the lactation process. One of the efforts to increase the breast milk production with SPEOS (Suggestive Endorphin Oxytocin Massage Stimulation). The SPEOS method can help nifas mother to facilitate the expenditure of breast milk. To know the effect of the SPEOS method (Suggestive Endorfin Oxytocin Massage Stimulation) on Breast Milk Production in Nifas Mothers. The research design used quasy experiment with one group pre-post test. Sample in this study was nifas mother with spontaneous childbirth amounted to 27 people. The sampling technique used consecutive sampling. Breastfeeding production before mothers performed SPEOS method on average was 3.70 ml with standard deviation of 5,113. Breast milk production after mother performed SPEOS method on average was 129,63 ml with standard deviation 11,001. There was an influence of SPEOS method to breast milk production on nifas mother at Maternity Hospital of Mardi Rahayu Semarang (p-value = 0,000). Stimulation Massage Endorphin Oxytocin SuggestifBreastmilk Production,Nifas Mother

scholarly journals The Effect of Torbangun Leaves Consumption on the Improvement of Breastmilk Volume in Post Partum Women in Ononamolo Village, Gunungsitoli City

2020 ◽  
Vol 4 (12) ◽  
pp. 400-403
Author(s):  
Ade Ayu Prawita ◽  
Siti Ewin Pasaribu
Keyword(s):  
Standard Deviation ◽  
Breast Milk ◽  
Post Partum ◽  
Intervention Group ◽  
Sampling Technique ◽  
Mean Value ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Control Group Design

Introduction: Insufficient volume of breastmilk production is the most common inhibiting factor leading to cessation of breastfeeding practice. This study aims to determine the effect of torbangun leaves (Coleus amboinicus lour) on the increase in breast milk volume in postpartum mothers in Ononamolo Village, Gunungsitoli Selatan District, Gunungsitoli City. Methods: The research design used a pre-experimental design with a pretest-posttest control group design. The population was post partum mothers in Ononamolo I Lot Village, Gunungsitoli Selatan District, Gunungsitoli City with a ratio of 1: 1. The sample size was 20 post partum mothers, selected using purposive sampling technique, with 1 intervention group given torbangun leaves for consumption for 14 consecutive days and 1 control group given booster milk to be consumed at the same time as the intervention group. The instrument used to measure milk production is to use a measuring cup. The results of data collection were analyzed by using the paired sample t-test. Results: Based on the research results obtained were the pre-test mean value of 6.10 with a standard deviation of 3.227, while in the post-test the average value was 10.95 with a standard deviation of 3.720. From the results of t-test with a confidence level of 95%, a p-value of 0.000 was obtained. Conclusion: There is an effect of the consumption of torbangun leaves on increasing the volume of breast milk in Ononamolo Village, Gunungsitoli Selatan District, Gunungsitoli City. Keywords: breastmilk volume production; torbangun leaves; post partum mothers

scholarly journals PENGARUH PEMBERIAN SEDUHAN DAUN KELOR TERHADAP KUANTITAS AIR SUSU IBU (ASI) PADA IBU MENYUSUI BAYI 0-6 BULAN DI WILAYAH KERJA PUSKESMAS SUMUR BATU KOTA BANDAR LAMPUNG

2020 ◽  
Vol 2 (3) ◽  
pp. 549-558
Author(s):  
Eka Trismiyana ◽  
Mei Kurnia Pitaloka
Keyword(s):  
Standard Deviation ◽  
Breast Milk ◽  
Health Center ◽  
Exclusive Breastfeeding ◽  
Standard Error ◽  
Community Health Center ◽  
P Value ◽  
Work Area ◽  
Quasi Experimental ◽  
Average Quantity

THE EFFECT OF GIVING KELOR LEAVES TOWARDS MILK (ASI) WATER QUANTITY IN 0-6 MONTHS OF BABY BREAST MILK IN WORKING AREAS OF HEALTH CENTER OF BATU BANDAR LAMPUNG CITY IN 2019 Introduction: Bandar Lampung City Health Office data shows that there are 3 Puskesmas with the lowest ASI coverage, namely Sumur Batu Health Center, with a total of 6 months exclusive breastfeeding coverage 142, as many as 102 infants (28.17%) did not receive exclusive breastfeeding at 6 months of age, and 40 ASI received exclusive breastfeeding, Way Kandis Health Center, with a total of 6 months exclusive breastfeeding coverage in 919, 621 infants (32.93%) did not receive exclusive breastfeeding aged 6 months, and 298 ASIs received exclusive breastfeeding, Kemiling Health Center, with total breastfeeding coverage exclusive 6 months 98, 62 babies (36.73%) did not get exclusive breastfeeding at the age of 6 months, and 36 ASIs received exclusive breastfeeding (Data from Bandar Lampung City Health Office, 2018). Objective: To determine the effect of administration of Moringa leaves on the quantity of breast milk in breastfeeding mothers of infants 0-6 months in the Work Area of Sumur Batu Health Center, Bandar Lampung City in 2019.Method: This type of research is quantitative. The design of the Quasi Experimental method is one group pretest-posttest one group pretest-posttest approach. Population and sample of 30 people. Data analysis uses univariate and bivariate with t-test.Results: The average quantity of breast milk in breastfeeding mothers of infants 0-6 months before being given moringa leaf steeping in the Sumur Batu Health Center Working Area, with a mean of 72.50 standard deviation 25.317 standard error 4.622, after being given steeping leaves of moringa mean 97.17 standard deviation of 17.601 standard error 3.214. P-value 0,000 (<0.05) t-test test results.Conclusion: means that there is an effect of steeping Moringa leaves on the quantity of breast milk in breastfeeding mothers of infants 0-6 months in the Sumur Batu Community Health Center Working Area in Bandar Lampung City in 2019. Suggestions for respondents are expected to be used as input for clients in order to know how to increase the smoothness of breast milk during breastfeeding. Keywords: Moringa Leaf Steeping, Breast Milk, Breastfeeding Mother  INTISARI: PENGARUH PEMBERIAN SEDUHAN DAUN KELOR TERHADAP KUANTITAS AIR SUSU IBU (ASI) PADA IBU MENYUSUI BAYI 0-6 BULAN DI WILAYAH KERJA PUSKESMAS SUMUR BATU KOTA BANDAR LAMPUNG TAHUN 2019 Pendahuluan: Data Dinas Kesehatan Kota Bandar Lampung menunjukan  bahwa terdapat 3 Puskesmas dengan cakupan pemberian ASI terendah yaitu, Puskesmas Sumur Batu, dengan total keseluruhan cakupan ASI eksklusif 6 bulan 142, sebanyak 102 bayi (28.17%) tidak mendapat ASI eksklusif usia 6 bulan, dan 40 ASI mendapat ASI eksklusif, Puskesmas Way Kandis, dengan total keseluruhan cakupan ASI eksklusif 6 bulan 919, sebanyak 621 bayi (32.93%) tidak mendapat ASI eksklusif usia 6 bulan, dan 298 ASI mendapat ASI eksklusif, Puskesmas Kemiling, dengan total keseluruhan cakupan ASI eksklusif 6 bulan 98, sebanyak 62 bayi (36.73%) tidak mendapat ASI eksklusif usia 6 bulan, dan 36 ASI mendapat ASI eksklusif (Data Dinkes Kota Bandar Lampung, 2018).Tujuan: Untuk mengetahui pengaruh pemberian seduhan daun kelor terhadap kuantitas air susu ibu (ASI) pada ibu menyusui bayi 0-6 bulan di Wilayah Kerja Puskesmas Sumur Batu Kota Bandar Lampung tahun 2019.Metode: Jenis penelitian ini adalah Kuantitatif. Desain penelitian metode Quasi Eksperimental pendekatan one group pretes-postes one group pretes-postes. Populasi dan sampel 30 orang. Analisa data mengguanakan univariat dan bivariate dengan t-tes.Hasil : Rata-rata kuantitas air susu ibu (ASI) pada ibu menyusui bayi 0-6 bulan sebelum diberi seduhan daun kelor di Wilayah Kerja Puskesmas Sumur Batu, dengan mean 72,50 standar deviasi 25,317  standar eror 4,622, setelah diberi seduhan daun kelor mean 97,17 standar deviasi 17,601  standar eror 3,214. Hasil uji t-tes p-value 0.000 (<0.05).Kesimpulan : artinya terdapat pengaruh pemberian seduhan daun kelor terhadap kuantitas air susu ibu (ASI) pada ibu menyusui bayi 0-6 bulan di Wilayah Kerja Puskesmas Sumur Batu Kota Bandar Lampung Tahun 2019. Saran bagi responden diharapkan hasil penelitian ini dapat digunakan sebagai masukan bagi klien agar dapat mengetahui bagaimana cara menambah kelancaran ASI pada masa menyusui. Kata Kunci             : Seduhan Daun Kelor, ASI, Ibu Menyusui 

STUDY OF SERUM ELECTROLYTES IMBALANCES IN FEMALE THYROID PATIENTS AT AIIMS, PATNA: A HOSPITAL BASED COMPARATIVE STUDY.

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Dr. Jyoti Kumari ◽  
Dr. Dev Kant ◽  
Dr. Mala Mahto
Keyword(s):  
Standard Deviation ◽  
Early Detection ◽  
P Value ◽  
Selective Electrode ◽  
Serum Electrolytes ◽  
Sodium Potassium ◽  
Paired Samples ◽  
Electrode Method ◽  
Hypothyroid Patients ◽  
Key Words Hypothyroidism

Objectives: This present study was to compare the serum electrolytes (Na, K and Cl) imbalances in hypothyroidism, hyperthyroidism with euthyroidism female cases. Methods: A detail history, clinical examinations and relevant investigations were performed to all female thyroid cases. Thyroid hormones were estimated by chemiluminiscence method using Siemens Advia Centaur XP instrument. Electrolyte levels (Na+, k+ & Cl-) were measured by ion selective electrode method using Eschweiler combi. Results: Data was analyzed with the help of SPSS (version 26) software. Paired samples statistics was used. Mean ± standard deviation and t value were calculated. P value was taken less than or equal to 0.05 (p ≤ 0.05) for significant differences. Conclusions: This present study concluded that electrolytes sodium, potassium and chloride levels were significantly reduced in hypothyroidism female cases compared to euthyroids female (controls). This suggests that hypothyroid patients should be regularly checked for serum electrolytes. Early detection and treatment can prevent the further complications related to the disorder and will be helpful during the management of thyroid patients. Key words: Hypothyroidism, hyperthyroidism, euthyroidism, electrolytes.

Penatalaksanaan IMD pada Ibu Postpartum Sectio Caesarea Mempengaruhi Status Gizi dan Kecepatan Produksi ASI

2020 ◽  
Vol 2 (2) ◽  
pp. 112-120
Author(s):  
Nursari Abdul Syukur ◽  
Susi Purwanti
Keyword(s):  
Breast Milk ◽  
Nutritional Status ◽  
Milk Production ◽  
Quantitative Research ◽  
Milk Protein ◽  
Sectio Caesarea ◽  
Control Group ◽  
P Value ◽  
Study Results

Many mothers who give birth to Sectio Caesarea (SC) do not Initiate Early Breastfeeding (IMD), which fails exclusive breastfeeding. This study aimed to determine the effect of IMD management in postpartum SC mothers on nutritional status, speed of milk production, and quality of breast milk protein. Method: quantitative research with quasi approach experiment. The research design used was a pre-post-test control non-equivalent control group. A sampling of this study used the Consecutive method sampling with a sample of 20 mothers who gave birth by cesarean section (SC). Hypothesis testing uses the independent t-test and the Mann-Whitney test. The study results showed an influence on the management of IMD in postpartum SC mothers on the speed of ASI production (p-value=0.004) and nutritional status (p-value=0.028). There was no effect of IMD management on postpartum SC mothers on the quality of breast milk protein (p-value = 0.543). This study recommends that the hospital implement an IMD promotion program before the abdominal wall is closed as a form of intervention to increase milk production and maternal nutritional status

Variasi Penambahan Tepung Daun Kelor (Moringa Oleifera Lam.) pada Pembuatan Flakes Ditinjau dari Sifat Fisik, Sifat Organoleptik dan Kadar Kalsium

2017 ◽  
Vol 19 (1) ◽  
pp. 31-35
Author(s):  
Frieda Rosita Majid ◽  
Nur Hidayat ◽  
Waluyo Waluyo
Keyword(s):  
Physical Characteristic ◽  
Nutritional Value ◽  
Calcium Content ◽  
Organoleptic Characteristics ◽  
High Calcium ◽  
Randomized Experimental Design ◽  
Leaf Powder ◽  
The Difference ◽  
The Tropics ◽  
Moringa Oleifera Lam

Background:Moringa (Moringaoleifera Lam.) Is a plant of high nutritional value, grows scattered in the tropics and sub-tropics, but utilization is still low. Each section has its benefits Moringa one part is the Moringa leaves contain a high calcium. In 100 grams of material, fresh Moringa leaves contain as much as 440 mg of calcium in the form of flour whereas if it contains as much as 2,003 mg of calcium. One of its use in the manufacture of flakes added. Objective: Know the difference physical harateristi, organoleptic characteristic and calcium levels in flakes variations addition of Moringa leaf powder. Methods: The study is a randomized experimental design with simple, includes four kinds of treatments, two replications with two experimental units. Observations of physical characteristic were analyzed by descriptive, the organoleptic characteristic of data analysis using statistical test Kruskal-Wallis continued Mann-Whitney and methods of test calcium content using permanganometri then the data were analyzed descriptive. Results: The physical characteristics of flakes greenish-yellow, slightly fragrant aroma typical of flakes, rather unpleasant taste typical of Moringa leaves and a slightly crunchy texture. Organoleptic characteristics the color of flakes with moringa leaf powder 5%, the aroma of the flakes without addition moringa leaf powder, the flavour of flakes with additions moringa leaf powder 5% and the texture of flakes with additions moringa leaf powder 7,5% most prefered panelist and high levels calcium of flakes with additions 10% moringa leaf powder. Conclusion: There is a difference variations addition of moringa leaf powder on physical, organoleptic characteristic (color) and the level of calcium flakes.Flakes with the addition of 5% moringa leaf powder is the most prefered panelist.   Keywords:Moringa Leaf Flour, Flakes, Physical characteristic, organoleptic, Calcium

Pengaruh Pemberian Rebusan Daun Ubi Jalar Terhadap Kecukupan ASI Pada Ibu Menyusui Di Wilayah Kerja Puskesmas Campurejo Kota Kediri

2017 ◽  
Vol 4 (1) ◽  
Author(s):  
Weni Tri Purnani
Keyword(s):  
Breast Milk ◽  
Vitamin A ◽  
Sweet Potato ◽  
Random Sampling ◽  
Simple Random Sampling ◽  
P Value ◽  
Work Area ◽  
Wilcoxon Sign Rank ◽  
Potato Extract ◽  
Sweet Potato Leaves

ABSTRAKASI merupakan sumber makanan yang mengandung nutrisi yang lengkap untuk bayi. Rendahnya cakupan ASI di Indonesia menyumbang akibat yang tidak baik bagi kesehatan bayi. Berdasarkan hasil survey pendahuluan, dari 10 ibu menyusui 6 (60%) diantaranya mengatakan bahwa pengeluaran ASI mereka tidak lancar. Salah satu solusi yang tepat untuk meningkatkan suplai ASI adalah dengan mengonsumsi daun ubi jalar yang dipercaya mengandung berbagai macam zat dan vitamin terutama vitamin A. Tujuan penelitian ini adalah mengetahui pengaruh pemberian rebusan daun ubi jalar terhadap kecukupan ASI pada ibu menyusui di Wilayah Kerja Puskesmas Campurejo Tahun 2016. Desain penelitian ini adalah pre eksperimental menggunakan rancangan pretest posttest design. Dalam penelitian ini diperoleh sampel 20 orang menggunakan teknik simple random sampling. Pengumpulan data dilakukan dengan menggunakan lembar kuesioner dan penilaian. uji hipotesis yang digunakan adalah uji peringkat bertanda dari wilcoxon dengan nilai signifikasi α = 0,05. Hasil uji statistik dari Wilcoxon Sign Rank diperoleh nilai p value = 0,000 dengan taraf kesalahan (α =0,05) dapat dikatakan p ≤ α maka dapat disimpulakan bahwa H0 ditolak dan H1 diterima. Hal ini berarti ada pengaruh pemberian rebusan daun ubi jalar terhadap kecukupan ASI pada ibu menyusui diwilayah kerja puskesmas campurejo kota Kediri tahun 2016. Berdasarkan hasil penelitian diharapkan bagi tenaga kesehatan dapat  dijadikan sebagai masukan untuk menggunakan daun ubi jalar untuk meningkatkan kecukupan ASI dalam pengembangan pengobatan tradisional. Kata Kunci : Kecukupan ASI, Daun Ubi jalar, Menyusui   ABSTRACTBreast milk is a food source that contains a complete nutritions for infants. Coverage of breast milk in Indonesia is still very low. Based on the preliminary results of the survey, from 10 breastfeeding mothers, there are 6 (60%) breastfeeding mom of them say that their breast milk isn’t enough for the babies. There’s a rightest solution to increase the breast milk supply, such as; the breastfeeding mom should eat or consume the sweet potato leaves that believed contains various nutritions and vitamins, especially vitamin A. The purpose of this study was to know the effect of giving sweet potato extract to breast milk adequacy on breastfeeding mothers in work area clinic of Campurejo Kediri City in 2016. The research design of this study was pre-experimental that using pre-test and post-test design. In this study obtained 20 samples of people that using simple random sampling technique. The collecting of data is done by using a questionnaires and assessment. The test hypothesis is marked on the Wilcoxon rank test with significance value α = 0.05. The result of statistical test Wilcoxon Sign Rank obtained p value = 0.000 with a standard error (α = 0.05) can be said p ≤ α then it means that H0 is rejected and H1 is accepted. This means that there is an effect of giving sweet potato extract to breast milk adequacy on breastfeeding mothers in work area clinic of Campurejo Kediri City in 2016. Based on the results is the researcher expecting for health workers can be used as input to use sweet potato leaves to improve the adequacy of breast milk in the development of traditional medicine. Keywords: Adequacy of Breast Milk, Sweet Potato Leaves, Breastfeeding.

Pengaruh Ekstrak Daun Moringa Oleifera terhadap Mean Platelet Volume dan Neutrophil-To-Lymphocyte Ratio pada Pasien Autoimun

2021 ◽  
Vol 6 (1) ◽  
pp. 355
Author(s):  
Nurhasan Agung Prabowo ◽  
Arief Nurudhin
Keyword(s):  
Rheumatoid Arthritis ◽  
Mean Platelet Volume ◽  
Moringa Oleifera ◽  
Neutrophil To Lymphocyte Ratio ◽  
P Value ◽  
Platelet Volume ◽  
Lymphocyte Ratio

Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak MO terhadap MVP dan NLR pada pasien autoimun. Metode penelitian yang digunakan adalah eksperimental yang dilakukan pada 30 pasien autoimun yang terdiri dari 28 pasien lupus dan 2 pasien rheumatoid arthritis di Poliklinik Reumatologi RSUD Moewardi pada Januari-Juli 2020. Pasien dikelompokkan menjadi dua, yaitu kelompok perlakuan dan kontrol. Pasien kelompok perlakuan mendapat 2gram ekstrak MO per hari, sedangkan pada kelompok kontrol mendapat plasebo. Perlakuan dilakukan selama 4 minggu, Pemeriksaan MPV dan NLR menggunakan haemositometer. Analisis statistik dilakukan dengan menggunakan uji-T berpasangan dan uji-T independen. Nilai p dianggap signifikan ketika p <0,05. Hasil penelitian menunjukkan bahwa MO menurunkan MPV (delta MPV = 4.141; r = 0.656; p = 0.02) dan NLR (delta NLR = 4.1391; r 0.489; p-value = 0.04). dapat disimpulkan MO menurunkan MPV dan NLR pada pasien autoimun.

Continuous glucose monitoring in acute stroke

2019 ◽  
Author(s):  
Laura Aponte-Becerra ◽  
Rodrigo Quispe ◽  
Laura Mendez-Pino ◽  
Vera Novak ◽  
Magdy Selim ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Acute Stroke ◽  
Continuous Glucose Monitoring ◽  
Poor Prognosis ◽  
Glucose Monitoring ◽  
Mean Amplitude ◽  
P Value ◽  
Stroke Patients ◽  
Glycaemic Variability ◽  
Acute Brain Ischemia

"Hyperglycaemia upon admission is a pathophysiological response to acute brain ischemia that has been independently associated with high mortality rate and poor prognosis. Glycaemic variability (GV) has also shown association with poor clinical outcomes among stroke patients. GV is best assessed by continuous glucose monitoring (CGM), which enables consecutives glucose measurements every 5 minutes. This pilot study aimed: 1) To describe safety, feasibility and tolerability of CGM in the acute stroke setting; and 2) To compare CGM and conventional FS glucose-based monitoring regimen in terms of their relationship with GUA and the accuracy of hypoglycaemic episodes detection. Safety, feasibility and tolerability of CGM was excellent in our cohort of 23 patients with acute stroke (61% ischemic and 39% intracerebral haemorrhage) and there were no adverse events. CGM recorded ten hypoglycaemic episodes that were not detected by conventional FS monitoring. GUA was associated with coefficient of variation (CV) of CGM (p=0.03), CV of FS (p=0.01), standard deviation (SD) of CGM (p-value=0.01) and mean amplitude of glucose excursions (MAGE) (pvalue= 0.001)."

Variants of the Circle of Willis as seen on magnetic resonance angiography and carotid siphon calcifications in community-dwelling older adults

2021 ◽  
pp. 197140092110428
Author(s):  
Oscar H Del Brutto ◽  
Bettsy Y. Recalde ◽  
Robertino M Mera
Keyword(s):  
Older Adults ◽  
Magnetic Resonance ◽  
Calcium Content ◽  
Circle Of Willis ◽  
Community Dwelling ◽  
Anatomical Variants ◽  
Study Results ◽  
High Calcium ◽  
Independent Association ◽  
Community Dwelling Older Adults

Background and purpose Information on the association between anatomical variants of the Circle of Willis (CoW) and intracranial atherosclerotic disease (ICAD) is limited and results are controversial. In this population-based study, we aimed to assess whether an incomplete CoW is associated with high calcium content in carotid siphons (a reliable biomarker of ICAD) in community-dwelling older adults of Amerindian ancestry. Methods Individuals aged ≥60 years enrolled in the Three Villages Study received a head computed tomography (CT) and magnetic resonance angiogram (MRA) of intracranial vessels. The CoW was classified in complete or incomplete according to the presence or absence of one A1 segment of the anterior cerebral artery or one or both P1 segments of posterior cerebral arteries. Calcium content in carotid siphons was rated as low or high. A multivariate logistic model was fitted to assess the independent association between incompleteness of the CoW and high calcium content in carotid siphons, after adjusting for demographics and cardiovascular risk factors. Results A total of 581 individuals were enrolled (mean age: 71 ± 8.4 years; 57% women). MRA revealed an incomplete CoW in 227 (39%) individuals, and high-resolution CT disclosed high calcium content in carotid siphons in 185 (32%). A risk factor logistic regression model showed no independent association between incompleteness of the CoW and high calcium content in carotid siphons (odds ratio: 0.91; 95% confidence interval: 0.62–1.34; p = 0.631). Conclusion Study results disclosed no association between anatomical variants of the CoW and the presence of high calcium content in carotid siphons.

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