STUDY OF SERUM ELECTROLYTES IMBALANCES IN FEMALE THYROID PATIENTS AT AIIMS, PATNA: A HOSPITAL BASED COMPARATIVE STUDY.

Author(s):  
Dr. Jyoti Kumari ◽  
Dr. Dev Kant ◽  
Dr. Mala Mahto

Objectives: This present study was to compare the serum electrolytes (Na, K and Cl) imbalances in hypothyroidism, hyperthyroidism with euthyroidism female cases. Methods: A detail history, clinical examinations and relevant investigations were performed to all female thyroid cases. Thyroid hormones were estimated by chemiluminiscence method using Siemens Advia Centaur XP instrument. Electrolyte levels (Na+, k+ & Cl-) were measured by ion selective electrode method using Eschweiler combi. Results: Data was analyzed with the help of SPSS (version 26) software. Paired samples statistics was used. Mean ± standard deviation and t value were calculated. P value was taken less than or equal to 0.05 (p ≤ 0.05) for significant differences. Conclusions: This present study concluded that electrolytes sodium, potassium and chloride levels were significantly reduced in hypothyroidism female cases compared to euthyroids female (controls). This suggests that hypothyroid patients should be regularly checked for serum electrolytes. Early detection and treatment can prevent the further complications related to the disorder and will be helpful during the management of thyroid patients. Key words: Hypothyroidism, hyperthyroidism, euthyroidism, electrolytes.

2016 ◽  
Vol 39 (3) ◽  
pp. 88 ◽  
Author(s):  
Murat Muratoglu ◽  
Cemil Kavalci ◽  
Elif Kilicli ◽  
Meliha Findik ◽  
Afşin Emre Kayipmaz ◽  
...  

Purpose: The purpose of this study was to investigate the role of serum neutrophil gelatinase-associated lipocalin (NGAL) levels in the early detection of contrast-induced nephropathy (CIN). Methods: This prospective study enrolled 74 patients undergoing abdominal tomography with contrast (1 November 2014 - 28 February 2015). Demographic properties (age and sex), symptoms and CT examination results were analysed. Sodium, potassium, urea, creatinine and NGAL levels were measured at 0th, 6th, and 72nd hours. P value < 0.05 was considered statistically significant. Results: CIN developed in 16.2% of the study patients. The mean age was significantly higher in the patients who developed CIN (p0.05). Urea levels did not differ significantly between the groups at 0th and 6th hours (p>0.05) but was significantly higher in the patients with CIN at 72nd hour (p0.05). Creatinine level was not significantly different between the groups (p>0.05) but increased significantly over time (p>0.05). There were no significant differences between the groups with respect to NGAL levels at 0th and 72nd hours (p>0.05) whereas the group with CIN had a significantly higher NGAL level at 6th hour (p


1975 ◽  
Vol 58 (3) ◽  
pp. 477-481 ◽  
Author(s):  
Laszlo Torma

Abstract A rapid and precise method for the determination of fluoride in feeds employs HC1 extraction of the sample. Acetate buffer and sodium citrate are added to control pH and ionic strength. The amount of fluoride is calculated from a standard curve after measuring the potentials of standard and sample solutions. Eight collaborators participated in the study of the method. Statistical values on 3 pairs of samples were calculated. The standard deviation, precision, coefficient of variation, and bias, respectively, were: Pair 1, 0.005071, 0.001763, 3.09, 0.0034; Pair 2, 0.037122, 0.006475, 1.82, 0.0258; Pair 3, 0.034587, 0.013021, 2.63, 0.0227. The results from the proposed method agreed favorably with the values obtained by using the official final action AOAC method, 7.089. The average and standard deviation, respectively, for individual samples by the proposed method were: Sample 3, 0.049, 0.0029; Sample 4, 0.059, 0.0021; Sample 5, 0.334, 0.0114; Sample 6, 0.341, 0.0101; Sample 7, 0.511, 0.0219; Sample 8, 0.492, 0.0237. By the official method the values were: Sample 3, 0.049, 0.0041; Sample 4, 0.058, 0.0029; Sample 5, 0.334, 0.0055; Sample 6, 0.331, 0.0082; Sample 7, 0.517, 0.0183; Sample 8, 0.499, 0.0175. The ion selective electrode method has been adopted as official first action.


Author(s):  
Galuh Pradian

anemiapregnant is a major cause of morbidity and mortality in the fetus and infant. The prevalence of anemia pregnant in PuskesmasSukorame still very high, on March-April 2016, there were 117 pregnant, as many as 33 people with a percentage of 38,6% of pregnant women suffer from anemia. The main cause of anemia among pregnant in Indonesia is a deficiency of iron, so that the government implement a program providing iron tablets one tablet per day for 90 days. The purpose of research to prove the effect of the consumption of cereals to changes in hemoglobin levels in anemic pregnant in Puskesmas Sukorame Kediri 2016.This study using Inferential with this type of Preeksperiment research, with pretest posttest design. The population are  33 people, while are 15 people taken at random.Based on statistical test mean Hb level of 9,4 g / dl, the standard deviation of 0.821 and the standard error was obtained 0,212 there as after intervention mean hemoglobin concentration of 10.4 g / dl, the standard deviation of 1,156 and 0,298 standard error of the data it can be seen an average increase in hemoglobin was 0,96 g / dl.Analysis of data obtained using Paired Samples Test 0.000 p value of <0.05, meaning there is the effect of consumption of cereals to changes in hemoglobin levels in anemic pregnant in Puskesmas Sukorame Kediri 2015.One of the nutritiontsthat containt of vitamin C and iron are cereals. Pregnant should consume iron tablet anemia accompanied consume nutritionts that contain of vitamin C and iron because its can help the nutritionts iron  of anemic pregnant. Keywords: Cereals, Tablet Fe, Pregnant, Anemia.


2019 ◽  
Vol 2 (2) ◽  
pp. 29-35
Author(s):  
Yuanita Ananda

ABSTRACT Yuniati's research (2018) in TK At Taqwa Mekarsari Cimahi showed that 17 puzzle intervention groups found that most of the children before being given puzzle type educational games, medium fine motoric (64.7%), the rest were (35.3% ) respondents have low fine motor development. The purpose of the study was to determine the effect of puzzle play therapy on fine motor development in pre-school children in Inti Tulip III Padang Kindergarten in 2018. This type of research is pre-experiment with one group pretest-posttest approach. The sample in this study were 15 children. The sampling technique used total sampling .. Data collection by observation on August 25, 2018. Data were analyzed by univariate and bivariate using paired samples T-test statistical test. The results of the study mean fine motor development before being given therapy to play puzzles in kindergarten Tulip III Core Group Padang mean 7.87 standard deviation 1.246. The mean fine motor development after being given therapy to play puzzles in kindergarten. Inti Tulip III Padang Group with a mean value of 9.93 standard deviation of 1.534. There is an effect of the child's fine motor development before and after therapy is playing puzzle in kindergarten Tulip Group III Padang in 2018  with p-value (0,000).. The conclusion of the research about playing puzzle therapy can affect fine motor skills in children. It is suggested that playing puzzle therapy can be applied at the kindergarten Tulip Group III. And it is hoped that this research can be developed with other therapies to see the fine motor development of pre-school children. Keywors: Puzzle Play Therapy and Fine Motor Development   ABSTRAK          Penelitian Yuniati (2018) di TK At Taqwa Mekarsari Cimahi didapatkan hasil bahwa 17 orang kelompok intervensi puzzle, didapatkan bahwa sebagian besar anak sebelum diberikan permainan edukatif jenis puzzle, motorik halusnya sedang yaitu (64,7%), selebihnya adalah (35,3%) responden memiliki perkembangan motorik halus rendah. Tujuan penelitian untuk mengetahui pengaruh terapi bermain puzzle terhadap perkembangan motorik halus pada anak pra sekolah di TK Inti Gugus Tulip III  Padang Tahun 2018. Jenis penelitian ini pre eksperimen dengan pendekatan one group pretest-posttest. Sampel pada penelitian ini adalah 15 anak. Teknik pengambilan sampel menggunakan total sampling.. Pengumpulan data dengan cara observasi pada tanggal 25 Agustus 2018. Data dianalisa secara univariat dan bivariat menggunakan uji statistik paired samples T-test. Hasil penelitian rerata perkembangan motorik halus sebelum diberikan terapi bermain puzzle di TK Inti Gugus Tulip III Padang dengan nilai mean 7,87 standar deviasi 1,246. Rerata perkembangan motorik halus sesudah diberikan terapi bermain puzzle di TK Inti Gugus Tulip III Padang dengan nilai mean 9,93 standar deviasi 1,534. Terdapat pengaruh perkembangan motorik halus anak sebelum dan sesudah dilakukan terapi bermain puzzle di TK.Inti Gugus Tulip III Padang tahun 2018 dengan p-value (0,000). Kesimpulan penelitian terapi bermain puzzle dapat mempengaruhi kemampuan motorik halus pada anak. Diharapkan terapi bermain puzzle dapat diterapkan di TK Inti Gugus Tulip III.  Dan diharapkan penelitian ini dapat dikembangkan dengan terapi lain untuk  melihat perkembangan motorik halus anak pra sekolah.   Kata Kunci : Terapi Bermain Puzzle dan Perkembangan Motorik Halus


2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Supriyadi . ◽  
Nurul Makiyah ◽  
Novita Kurnia Sari

<p><em>Buerger Allen Exercise</em> mampu meningkatkan pemakaian glukosa oleh otot yang aktif sehingga glukosa dalam darah dapat menurun, dapat membantu mencegah terjadinya penyakit arteri perifer, serta meningkatkan aliran darah ke arteri dan berefek positif pada metabolisme glukosa. Penelitian ini bertujuan untuk mengetahui nilai <em>ankle brachial index</em>pada penderita diabetes melitus tipe 2setelah melakukan <em>Buerger Allen exercise</em>. Jenis penelitian ini adalah <em>quasy-experiment </em>dengan<em> pre-post test design with control group</em><em>.</em> Jumlah sampel 60 penderita diabetes melitus tipe 2 dengan <em>purposive sampling</em>, dibagi menjadi 2 kelompok yaitu kelompok perlakuan dan kelompok kontrol. Responden kelompok perlakuan diberikan intervensi <em>Buerger Allen exercise</em> sebanyak 12 kali  selama 15 hari.Penelitian dilakukan di wilayah Puskesmas Kecamatan Nganjuk.Data hasilpengukuran nilai <em>ankle brachial index</em>berupa ratio dan diuji statistik dengan <em>Paired Samples Test</em>. Didapatkan <em>p value</em> 0.001 untuk kelompok perlakuan (<em>p value</em>&lt; 0.05) yang menunjukkan bahwa adanya perubahan bermakna secara statistik nilai <em>ankle brachial index</em> sesudah melakukan <em>Buerger Allen exercise</em>. Dapat disimpulkan bahwa nilai <em>ankle brachial index</em>pada penderita diabetes melitus tipe 2 meningkat sesudah melakukan <em>Buerger Allen exercise</em>.</p><p> </p><p> <strong>Kata kunci :penderita diabetes melitus tipe2, <em>Buerger Allen Exercise, Ankle brachial index</em></strong></p><p> </p>


Author(s):  
Eliyas Sulaiman Mohandas ◽  
Nik Mastura Nik Ismail Azlan ◽  
Salwa Othman ◽  
Muhammad Aizat Azhari

This study aims to investigate whether the use of six selected short stories throughout the duration of a 14-week course could enhance students’ reading comprehension achievement at the end of the semester. Out of the six short stories read, three were chosen as in-class assignments known as ‘Personal Reading Logs’ (hereafter, PRLs). One group of semester two Diploma students taking a reading skills course was selected through a convenience sampling method. A pre-test was conducted by having the students answer a past semester reading quiz of which the results would then be compared to their post-test (final reading exam) results. A paired samples t-test revealed no significant difference in the reading scores of the pre-test and the post-test, t (17) = -.265, p > .05. Since the p-value was bigger than 0.05, this indicated that the mean reading score of the post-test (M = 50.556) was not significantly higher than the mean reading score of the pre-test (M = 49.722). Therefore, the null hypothesis which stated that there was no difference in the mean score of the pre-test and post-test was retained. Overall, the result refuted the findings of other studies promoting the effectiveness of using short stories to enhance L2 reading comprehension achievement.


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S97-S97
Author(s):  
Christina M Kaul ◽  
Eric Molina ◽  
Donna Armellino ◽  
Mary Ellen Schilling ◽  
Mark Jarrett

Abstract Background Overutilization of antibiotics remains an issue in the inpatient setting. What is more, many protocols geared toward curbing improper antibiotic use rely heavily on resource- and personnel-intensive interventions. Thus, the potential for using the EMR to facilitate antibiotic stewardship remains largely unexplored. Methods We implemented a novel change for ordering certain antibiotics in our EMR: ceftriaxone, daptomycin, ertapenem, imipenem, meropenem, and piperacillin-tazobactam. When ordering one of these antibiotics, providers had to note a usage indication, which assigned a usage duration as per our Antibiotic Stewardship Committee guidelines. Pre-intervention, manual discontinuation was required if a provider did not enter a duration. The intervention was enacted August 2019 in 13 hospitals. Data was collected from January 2018 to February 2020. Antibiotic usage was reported monthly as rate per 1000-patient days. Monthly pre- and post-intervention rates were averaged, respectively. Paired samples t-tests were used to compare pre- and post-intervention rates per unit type per hospital. A p-value of less than 0.05 was considered significant. Units with minimal usage, as defined by a pre- or post-intervention mean of 0, were excluded from analysis. Example of Ordering an Antibiotic Prior to Intervention Example of Ordering an Antibiotic After Intervention Results Ertapenem was noted to have a statistically significant decrease in utilization in seven units at three hospitals. Piperacillin-tazobactam was found to have a decrease in utilization in 19 units at eight hospitals. Daptomycin was found to have a decrease in utilization in one unit. Significant decreases in the utilization of ceftriaxone, imipenem, and meropenem were not noted. Example of Statistically Significant Decreased Utilization in Piperacillin-Tazobactam on a Medical-Surglcal Unit Conclusion Our study showed a statistically significant decrease in use of ertapenem, piperacillin-tazobactam and daptomycin using a simple built-in EMR prompt that curtails provider error. This should allow for an increased ease of integration, as the protocol does not require a host of resources for maintenance. Of note is decreased utilization of piperacillin-tazobactam and ertapenem across multiple hospitals, most notably on the medical and surgical wards. Thus, usage of the EMR without personnel-intensive protocols is a viable method for augmenting antibiotic stewardship in health systems. Disclosures All Authors: No reported disclosures


2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Kwuntida Uthaisar Kotepui ◽  
Manas Kotepui ◽  
Chuchard Punsawad

Malaria is a potential medical emergency and should be treated immediately because delays in diagnosis and treatment are the leading causes of death in many countries. This study aimed to assess the knowledge, attitude, and practice related to malaria diagnosis for early detection among healthcare workers in the laboratories of hospitals in Thailand. The design of the study was a descriptive cross-sectional study carried out between January 2016 and March 2017 at 11 hospitals in Thailand. The interviewees included any scientists who were currently working in a medical laboratory. Mean scores for knowledge, attitude, and practice for each healthcare group were calculated and compared between groups. Data analysis was performed using the SPSS version 11.5 software package (SPSS Inc., Chicago, IL, USA). Among a total of 118 healthcare workers, most of the healthcare workers had fair to good knowledge, attitude, and practice related to malaria detection. Among the various positions of healthcare workers, medical technologists possessed a greater knowledge on malaria detection than medical technician assistants or laboratory assistants (X2 = 9.822, d.f. = 2, and P value=0.007). This study infers that knowledge, attitude, and practice related to malaria detection among healthcare workers in laboratories were adequate. However, some points of knowledge and practice must be updated. There is a very urgent need to update knowledge on malaria, especially about the number of Plasmodium species causing relapse in malaria patients. In addition, there is an urgent need to update the practice related to malaria detection, especially about the staining process for early detection of malaria.


Author(s):  
Laura Aponte-Becerra ◽  
Rodrigo Quispe ◽  
Laura Mendez-Pino ◽  
Vera Novak ◽  
Magdy Selim ◽  
...  

"Hyperglycaemia upon admission is a pathophysiological response to acute brain ischemia that has been independently associated with high mortality rate and poor prognosis. Glycaemic variability (GV) has also shown association with poor clinical outcomes among stroke patients. GV is best assessed by continuous glucose monitoring (CGM), which enables consecutives glucose measurements every 5 minutes. This pilot study aimed: 1) To describe safety, feasibility and tolerability of CGM in the acute stroke setting; and 2) To compare CGM and conventional FS glucose-based monitoring regimen in terms of their relationship with GUA and the accuracy of hypoglycaemic episodes detection. Safety, feasibility and tolerability of CGM was excellent in our cohort of 23 patients with acute stroke (61% ischemic and 39% intracerebral haemorrhage) and there were no adverse events. CGM recorded ten hypoglycaemic episodes that were not detected by conventional FS monitoring. GUA was associated with coefficient of variation (CV) of CGM (p=0.03), CV of FS (p=0.01), standard deviation (SD) of CGM (p-value=0.01) and mean amplitude of glucose excursions (MAGE) (pvalue= 0.001)."


2018 ◽  
Vol 30 (2) ◽  
pp. 259-264
Author(s):  
Priya Arjunwadekar ◽  
Savitri Parvatgouda Siddanagoudra

Abstract Background A significant relationship has been documented in the literature between the autonomic nervous system imbalance and cardiovascular mortality. In patients with autonomic failure, water ingestion has been shown to increase blood pressure (BP), induce bradycardia, and cause low heart rate variability (HRV). A few studies showed the altered HRV as an acute effect of ice water intake in healthy subjects. None of the studies have shown light on the relationship of BP and HRV to ice water intake in obese and overweight subjects. The present study is aimed to correlate BP and HRV with body mass index (BMI) after ice water ingestion. Methods This cross-sectional study included a total of 60 subjects of both sexes aged between 18 and 24 years old. Subjects were assigned into three groups based on their BMI: normal, overweight, and obese. Before and after ice water ingestion, BP and HRV parameters were recorded and compared between the groups. Statistically data were analyzed by Student’s paired t-test and one-way analysis of variance. Results Basal HF was significant (p<0.05) in all three groups after ice water ingestion [F(2, 27), 44.1; p-value, 0.02]. After ice water ingestion, all HRV values were significant (p<0.001) in the three groups. The post-hoc Tukey HSD test demonstrated the less mean score for mean RR interval, standard deviation of all NN interval, standard deviation of differences between adjacent, HF and high for HR, LF, and LHR in overweight and obese subjects. Conclusions Because of the effective buffering system, healthy subjects showed increased HR and unchanged BP. Overweight and obese subjects showed decreased HR and increased BP.


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