scholarly journals Opioid use and diabetes: An overview

2016 ◽  
Vol 04 (01) ◽  
pp. 006-010 ◽  
Author(s):  
Pawan Sharma ◽  
Yatan Balhara
Keyword(s):  
Public Health ◽  
Endocrine System ◽  
Public Health Problem ◽  
Health Concern ◽  
Past Century ◽  
Major Public Health Problem ◽  
Opioid Use ◽  
Public Health Concern ◽  
The Past ◽  
Chronic Effects

AbstractIllicit opioids have emerged as a major public health problem over the past century. It continues to remain so in the current times. From the studies conducted among the animals, it has been clear that there are acute as well as chronic effects of opioids on the endocrine system. Diabetes has been recognized as a major public health concern and is expected to be a major problem in the coming decades. In this article, we shall discuss the effects of opioids in the glucose homeostasis in both the animal population and human population and its relation to diabetes.

scholarly journals Epidemic Alphaviruses: Ecology, Emergence and Outbreaks

2020 ◽  
Vol 8 (8) ◽  
pp. 1167 ◽  
Author(s):  
Sasha R. Azar ◽  
Rafael K. Campos ◽  
Nicholas A. Bergren ◽  
Vidyleison N. Camargos ◽  
Shannan L. Rossi
Keyword(s):  
Public Health ◽  
Human Health ◽  
Significant Risk ◽  
Present Review ◽  
Health Concern ◽  
Past Century ◽  
Significant Morbidity ◽  
Public Health Concern ◽  
The Past ◽  
Human Use

Over the past century, the emergence/reemergence of arthropod-borne zoonotic agents has been a growing public health concern. In particular, agents from the genus Alphavirus pose a significant risk to both animal and human health. Human alphaviral disease presents with either arthritogenic or encephalitic manifestations and is associated with significant morbidity and/or mortality. Unfortunately, there are presently no vaccines or antiviral measures approved for human use. The present review examines the ecology, epidemiology, disease, past outbreaks, and potential to cause contemporary outbreaks for several alphavirus pathogens.

scholarly journals General hospital services in the UK for adults presenting after self-harm: little evidence of progress in the past 25 years

2020 ◽  
Vol 217 (6) ◽  
pp. 661-662
Author(s):  
Allan House ◽  
David Owens
Keyword(s):  
Public Health ◽  
Effective Action ◽  
Health Concern ◽  
Hospital Services ◽  
Public Health Concern ◽  
Services Research ◽  
The Past ◽  
Self Harm ◽  
The Uk ◽  
Research And Policy

SummarySelf-harm remains a serious public health concern, not least because of its strong link with suicide. Twenty-five years ago we lamented the deficits in UK services, research and policy. Since then, there has not been nearly enough effective action in any of these three domains. It is time for action.

scholarly journals Arthritogenic Alphavirus Capsid Protein

Life ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 230
Author(s):  
Shambhavi Rao ◽  
Adam Taylor
Keyword(s):  
Public Health ◽  
Capsid Protein ◽  
Health Concern ◽  
Multiple Infection ◽  
High Morbidity ◽  
Public Health Concern ◽  
Virion Assembly ◽  
Diagnostic Strategies ◽  
The Past ◽  
Infection Processes

In the past two decades Old World and arthritogenic alphavirus have been responsible for epidemics of polyarthritis, causing high morbidity and becoming a major public health concern. The multifunctional arthritogenic alphavirus capsid protein is crucial for viral infection. Capsid protein has roles in genome encapsulation, budding and virion assembly. Its role in multiple infection processes makes capsid protein an attractive target to exploit in combating alphaviral infection. In this review, we summarize the function of arthritogenic alphavirus capsid protein, and describe studies that have used capsid protein to develop novel arthritogenic alphavirus therapeutic and diagnostic strategies.

scholarly journals Ghrelin, Diabetes and Obesity - Prospects for an Anti-obesity Vaccine

JMS SKIMS ◽  
2011 ◽  
Vol 14 (2) ◽  
pp. 38-39
Author(s):  
Shariq R Masoodi
Keyword(s):  
Public Health ◽  
Type 2 Diabetes ◽  
Public Health Problem ◽  
Healthcare Systems ◽  
Major Public Health Problem ◽  
Human History ◽  
The Past ◽  
The Usa ◽  
Diabetes And Obesity

The prevalence of diabetes is increasing worldwide and nowadays stands as a major public health problem. Undoubtedly, the 21st century has the most diabetogenic environment in human history. The number of people living with diabetes has soared to 366 million, and the disease kills one person every seven seconds, posing a "massive challenge" to healthcare systems worldwide. Diabetes is a huge and growing problem, and the costs to society are high and escalating, affecting all countries. Over the past 25 years or so, the prevalence of type 2 diabetes in the USA has almost doubled, with three- to five-fold increases in India, Indonesia, China, Korea and Thailand. JMS 2011;14(2):38-39.

Study of antibiotics resistance in bacteria isolated from retailed eggshell in three major markets in Minna, Nigeria

2020 ◽  
pp. 3709-3719
Author(s):  
N.U. Adabara ◽  
C.E. Amarachi ◽  
A.S. Adedeji ◽  
A. Usman ◽  
M. Maude ◽  
...  
Keyword(s):  
Public Health ◽  
Public Health Problem ◽  
Developed Countries ◽  
Multidrug Resistant ◽  
Total Coliform ◽  
Health Concern ◽  
Resistant Bacteria ◽  
Antibiotics Resistance ◽  
Major Public Health Problem ◽  
Antibiotic Susceptibility Test

Food borne disease associated with inappropriately treated or untreated eggs is a major public health problem affecting developing and developed countries. This study isolated, identified and determined the Antibiogram of bacteria isolates from eggshell of eggs obtained from three major markets in Minna, Nigeria. A total of ten (10) duplicate egg samples were purchased from egg retailers. The egg samples were analyzed for the enumeration and isolation of bacteria. The isolated bacteria were identified using biochemical methods. Antibiotic susceptibility test to prescribed commercially available antibiotic discs was also investigated. The total viable bacteria count (TVBC) ranged from 1.38×104 - 2.52×104 cfu/mL while the total coliform count (TCC) ranged from 8.5×103 - 2.02×104 cfu/mL. Escherichia coli (9.1%), Streptococcus pyogenes (4.5%), Enterococcus sp. (4.5%), Shigella sp. (13.6%), Salmonella sp. (13.6%), Staphylococcus aureus (36.4%), Clostridium sp. (9.1%) and Neisseria sp. (9.1%) were isolated and identified from eggshells. Gram positive bacteria showed highest sensitivity to gentamycin (100%) however, resist cloxacillin, ceftadizime and erythromycin (100%). Similarly, there was no ciprofloxacin resistant Gram-negative bacteria though E. coli, Salmonella sp. and Shigella sp. isolated from eggshells were resistant to augmentin and amoxicillin. Further analysis of result revealed that all the isolated bacteria from eggshells were multidrug resistant except Neisseria sp. with multidrug resistant index greater than 0.2. The fact that these antibiotic resistant bacteria can be transferred to humans is of public health concern. Therefore, stringent use of public health regulations for cleaning eggs before retailing is advocated.

scholarly journals Seroprevalence of Cysticercosis in Children and Young Adults Living in a Helminth Endemic Community in Leyte, the Philippines

2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Jin-Mei Xu ◽  
Luz P. Acosta ◽  
Min Hou ◽  
Daria L. Manalo ◽  
Mario Jiz ◽  
...  
Keyword(s):  
Public Health ◽  
Taenia Solium ◽  
Public Health Problem ◽  
The Philippines ◽  
Health Concern ◽  
Public Health Concern ◽  
Significant Difference ◽  
Significant Public Health Problem ◽  
Significant Public Health ◽  
Children And Young Adults

Cysticercosis is a significant public health problem in countries where pigs are raised for consumption and remains an important cause of neurological disease worldwide. The Philippines is considered an endemic area for cysticercosis because cases in both humans and pigs have been reported; however, epidemiologic information stays limited. We conducted a pilot survey of the seroprevalence of human cysticercosis in a village in Leyte, the Philippines, by measuring antibody specific forTaenia soliumcyst-fluid antigen. There were 497 subjects aged 7–30 years in our study and most subjects were infected with one or more helminths. The overall cysticercosis seroprevalence in this population was 24.6% (95% CI: 20.82% ~ 28.58%) with no significant difference based on age, sex, or other helminth coinfection status. Although the sample may not be representative of the whole community, the findings suggest that cysticercosis is a significant, but underrecognized public health concern in the Philippines.

Malaria Reports, a new journal

2011 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Niko Speybroeck
Keyword(s):  
Public Health ◽  
Malaria Control ◽  
Large Scale ◽  
Indoor Residual Spraying ◽  
Public Health Problem ◽  
Bed Nets ◽  
Major Public Health Problem ◽  
The Past ◽  
Combination Treatments ◽  
International Funding

International funding for malaria control has raised significantly in the past decade, leading to large-scale indoor residual spraying campaigns, to the distribution of insecticidetreated bed nets, and to the introduction of artemisinin-based combination treatments. An encouraging reduction of malaria cases has been reported in a number of countries, but malaria remains a major public health problem worldwide (WHO, 2010). People living in the poorest countries are the most vulnerable. Therefore, it remains a challenge to ensure that high levels of coverage and caution are maintained and that efforts aimed at developing an effective and affordable vaccine would be amplified.

scholarly journals The epidemiology and health burden of neurocysticercosis in tertiary hospital of Nepal

2014 ◽  
Vol 4 (2) ◽  
pp. 13-16
Author(s):  
RB Sah ◽  
L Subedi ◽  
N Pandey ◽  
BP Sah ◽  
S Jha ◽  
...  
Keyword(s):  
Public Health ◽  
Secondary Data ◽  
Tertiary Hospital ◽  
Health Concern ◽  
Age Group ◽  
Public Health Concern ◽  
Medical College ◽  
The Past ◽  
The Central Nervous System ◽  
Record Section

Neurocysticercosis (NCC) is the most common parasitic infestation of the central nervous system and is one of the major public health problems in developing nations like Nepal. This study was conducted to find out total number of neurocysticercosis cases in BPKIHS from 2005 to 2013 AD and to know the duration for which cases were admitted and improvement seen in them. This is a hospital based retrospective study conducted from 31st March to 13th April 2014 to see the number of NCC in B P Koirala Institute of Health Sciences, Dharan of Nepal, a tertiary level referral hospital in the Eastern Nepal. It was study in which secondary data, consistent with the diagnosis of Neurocysticercosis was collected from the Medical Record Section of BPKIHS and reviewed. One hundred fourteen cases of neurocysticercosis were enrolled. The patients were predominantly males (nearly 63.2%) and it was more commonly seen in 2-20 years age group (42%). Most of the cases were from Sunsari District. Most of the patients (63.2%) were admitted in Medicine wards. Almost 90.4% of admitted Neurocysticercosis cases were improved in BPKIHS. The trend of Neurocysticercosis cases did not show any showed any consistent pattern in the past nine years. We conclude that the problem of Neurocysticercosis is common and has become a key public health concern for all. DOI: http://dx.doi.org/10.3126/jcmc.v4i2.10854 Journal of Chitwan Medical College 2014; 4(2): 13-16

scholarly journals Persistent High Leptospiral Shedding by Asymptomatic Dogs in Endemic Areas Triggers a Serious Public Health Concern

Animals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 937
Author(s):  
Ricardo Sant’Anna da Costa ◽  
Maria Isabel N. Di Azevedo ◽  
Ana Luiza dos Santos Baptista Borges ◽  
Filipe Anibal Carvalho-Costa ◽  
Gabriel Martins ◽  
...  
Keyword(s):  
Public Health ◽  
Clinical Signs ◽  
Public Health Problem ◽  
Health Concern ◽  
Public Health Concern ◽  
Blood Samples ◽  
Renal Changes ◽  
Endemic Areas ◽  
One Year

(1) Background: Dogs are known as hosts of Leptospira interrogans and can spread this bacterium to the environment. Although Canicola is responsible for determining chronic disease in dogs, when affected by incidental serogroups such as Icterohaemorrhagiae, acute disease may occur with a predominance of clinical signs with hepatic and renal changes. In endemic areas, it is a serious public health problem. Thus, this study aims to estimate the incidence and duration of elimination of leptospires in the urine of dogs, taking another step from a previous study of our group, by a longitudinal, long-term and molecular approach. (2) Methods: A total of 125 dogs without apparent symptoms of leptospirosis were included in the study. The dogs were all PCR-negative and seronegative at the beginning of the study. Blood samples were collected for hematological examinations and urine for amplification of the lipL32 gene by PCR at five different time points during one year. (3) Results: Out of the 125 dogs, 62 became lipL32 PCR-positive (48.8% (95% CI, 47.9–49.7%)) at some point during the study, distributed as follows: at day 0, all negative; day 90, 18/125 (14.4% (95% CI, 13.5–15.3%)); day 180, 18/125 (14.4% (95% CI, 13.5–15.3%)); day 270, 12/125 (9.6% (95% CI, 8.7–10.5%)); and day 365, 14/125 (11.2% (95% CI, 10.3–12.1%)). Out of the 62 amplicons, 22 were sequenced, targeting a short region of secY gene. Of these, 20 (90.9%) were identical to the L. interrogans serovar Icterohaemorrhagiae, while two (9.1%) were Leptospira noguchii. (4) Conclusions: The fact that the leptospires of the Icterohaemorrhagiae serogroup were characterized was unexpected, since the animals remained clinically asymptomatic during the study. The fact that asymptomatic dogs shed leptospires is not new, but the extent of this fact and the characterized strain is impressive, with an impact on public health that cannot be overlooked.

scholarly journals Diagnosis Klinis Demam Berdarah Dengue di Tiga Kabupaten/Kota Sulawesi Tengah Tahun 2015-2016

2018 ◽  
Vol 12 (2) ◽  
pp. 77-86
Author(s):  
Hayani Anastasia
Keyword(s):  
Public Health ◽  
Clinical Diagnosis ◽  
Health Problem ◽  
Dengue Infection ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
The Past ◽  
Health Practitioners ◽  
Dengue Outbreaks ◽  
Central Sulawesi

Abstract Dengue is a major public health problem in Indonesia including Central Sulawesi. In the past, Palu was the only city reported high dengue cases. Then,  dengue outbreaks were also reported from several districts in Central Sulawesi. The Provincial Health Office suspected over-reporting of dengue infection. This reviewed article was aimed to identify whether the clinical diagnosis was the cause of over-reporting of dengue infection. Data of dengue cases from three districts/city in 2015-2016 were analyzed descriptively. The results showed that there was an over-reporting of dengue infection by 51.7%. The over-reporting occurred because the diagnosis of cases was not strictly followed the guideline for dengue infection classification by the Ministry of Health. Therefore, it is necessary for the health practitioners to understand fully the guideline of dengue infection classification used in Indonesia. Abstrak Dengue merupakan salah satu masalah kesehatan utama di Indonesia, termasuk di Sulawesi Tengah. Kota Palu merupakan daerah endemis Demam Berdarah Dengue (DBD) utama di Sulawesi Tengah. Namun, dalam beberapa tahun terakhir kejadian luar biasa DBD dilaporkan di beberapa kabupaten. Dinas Kesehatan Provinsi Sulawesi Tengah menduga adanya kemungkinan over-reporting kasus DBD yang menyebabkan meningkatnya laporan kasus DBD setiap tahunnya. Review ini bertujuan untuk mengidenfikasi kemungkinan adanya over-reporting kasus DBD di tiga kabupaten/kota di Sulwesi Tengah. Data kasus DBD tahun 2015-2016 dianalisis secara deskriptif untuk melihat adanya over-reporting. Hasil menujukkan bahwa terdapat kelebihan 51,7% kasus DBD yang disebabkan karena diagnosis tidak mengikuti kriteria diagnosis klinis sesuai panduan klasifikasi infeksi dengue yang dikeluarkan oleh Kementerian Kesehatan. Oleh karena itu sangat penting bagi klinisi untuk memahami kriteria diagnosis infeksi dengue yang digunakan di Indonesia.  

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