Adverse effects in broiler chickens fed a high lycopene concentration supplemented diet

2013 ◽  
Vol 93 (2) ◽  
pp. 231-241 ◽  
Author(s):  
Luisa Pozzo ◽  
Martina Tarantola ◽  
Elena Biasibetti ◽  
Maria Teresa Capucchio ◽  
Maddalena Pagella ◽  
...  
Keyword(s):  
Antioxidant Enzymes ◽  
Adverse Effects ◽  
Broiler Chickens ◽  
Femoral Vein ◽  
Basal Diet ◽  
Bursa Of Fabricius ◽  
Control Group ◽  
Broiler Chicks ◽  
Breast Meat ◽  
Liver And Kidney

Pozzo, L., Tarantola, M., Biasibetti, E., Capucchio, M. T., Pagella, M., Mellia, E., Bergagna, S., Gennero, M. S., Strazzullo, G. and Schiavone, A. 2013. Adverse effects in broiler chickens fed a high lycopene concentration supplemented diet. Can. J. Anim. Sci. 93: 231–241. The present investigation was designed to assess the effects of the administration of a high dietary lycopene dose to broiler chickens on growth and slaughter performances, haemato–biochemical parameters, antioxidant enzymes, histological lesions and lycopene accumulation in the tissues. Thirty-six 1-d-old male Hubbard broiler chicks were examined and divided randomly into two groups (three replicates for each dietary treatment): the Control group, which received a basal diet, and the Lycopene group, which received the basal diet supplemented with 500 mg lycopene kg−1diet. The experimental period lasted 35 d and growth performance was recorded on a weekly basis. At the end of the experiment (day 35), blood samples (n=12) were collected from the femoral vein. Erythrocyte and leukocyte numbers were assessed and the heterophil-to-lymphocyte ratio was determined. The alpha-1-acid glycoprotein, lysozyme, total protein and the electrophoretic patterns were evaluated in serum samples. Nine chickens per group were slaughtered to measure the carcass yields and the weight of the liver, spleen, bursa of Fabricius and thymus. Spleen, liver, and bursa of Fabricius samples were collected for histological examination and fixed in 10% neutral buffered formalin. The lycopene concentration, thiobarbituric acid reactive substances (TBARS) and chemical composition were assayed in breast meat and thigh samples. The TBARS, glutathione content, catalase and superoxide dismutase activity were measured in liver and kidney samples. The high lycopene concentration supplemented diet did not affect the birds’ growth, slaughter performance or antioxidant enzymes in the breast meat, thigh meat, liver and kidney samples. The concentrations of lycopene in the breast and thigh of the lycopene-supplemented group were 0.10±0.05 mg kg−1and 0.42±0.35 mg kg−1, respectively, while no lycopene was found in the Control group. Spleen and bursa of Fabricius of birds fed a diet supplemented with a high level of lycopene showed weight decrease (P<0.05) and degenerative lesions (P<0.05). Moreover, lycopene supplementation reduced the serum protein concentration, albumin, alpha and the gamma globulin serum concentration (P<0.05).

scholarly journals Effect of Adding Different Levels of Portulaca oleracea L. Seeds and Leaves Powder to The Diet on Productive and Physiological Performance of Broiler Chickens (Ross 308)

2021 ◽  
Vol 34 (1) ◽  
pp. 38-48
Author(s):  
Ahmed J. Shirshaab ◽  
Jaffar M. Jassim
Keyword(s):  
Broiler Chickens ◽  
Basal Diet ◽  
Serum Glucose ◽  
Portulaca Oleracea ◽  
Control Group ◽  
Broiler Chicks ◽  
Positive Role ◽  
Randomized Design ◽  
Escherichia Coli Bacteria ◽  
Different Levels

This study was conducted in the Poultry Field of the College of Agriculture, Basrah University for the period from 20/9/2019 to 24/10/2019 to investigate the effect of adding different levels of Portulaca oleracea L. seeds and leaves powder on some physiological characteristics of broilers. A total 216 one day old unsexed Ross-308 broiler chicks were used in this study. The chicks were randomly distributed into six treatments replicated three times (12 chicks each replicate). The experiment was designed as a completely randomized design (CRD). The first treatment was control (basal diet), P. oleracea seed powder was added as 5 & 10 g.kg-1 for the 2nd and 3rd treatments. Leaves powder was added as 5 and 10 g.kg-1 to the basal diet in treatment 4th and 5th. In the 6th treatment 5 gm of seed and 5 gm of leaves powder was added to the basal diet. The results showed that there was a significant (P <0.05) decrease in serum glucose, cholesterol and triglyceride concentrations in all additive treatments compared to control. There was also a significant decrease (P <0.05) in Escherichia coli bacteria count, as well as a significant improvement (P <0.05) in the number of Lactobacilli bacteria in all addition treatments compared to the control group. The addition of P. oleracea seeds and leaves powder had no significant effect on some haematological indices and on the total protein concentration in the serum. The study confirms the importance of adding powder of seeds or leaves in the broiler diet because it has a positive role in improving some of the physiological and microbial blood characteristics of the broiler.

scholarly journals Effect of Dietary Lead on Intestinal Nutrient Transporters mRNA Expression in Broiler Chickens

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Roohollah Ebrahimi ◽  
Mohammad Faseleh Jahromi ◽  
Juan Boo Liang ◽  
Abdoreza Soleimani Farjam ◽  
Parisa Shokryazdan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Antioxidant Enzymes ◽  
Growth Performance ◽  
Feed Efficiency ◽  
Broiler Chickens ◽  
Body Weight Gain ◽  
Basal Diet ◽  
Broiler Chicks ◽  
Nutrient Transporters

Lead- (Pb-) induced oxidative stress is known to suppress growth performance and feed efficiency in broiler chickens. In an attempt to describe the specific underlying mechanisms of such phenomenon we carried out the current study. Ninety-six one-day-old broiler chicks were randomly assigned to 2 dietary treatment groups of 6 pen replicates, namely, (i) basal diet containing no lead supplement (control) and (ii) basal diet containing 200 mg lead acetate/kg of diet. Following 3 weeks of experimental period, jejunum samples were collected to examine the changes in gene expression of several nutrient transporters, antioxidant enzymes, and heat shock protein 70 (Hsp70) using quantitative real-time PCR. The results showed that addition of lead significantly decreased feed intake, body weight gain, and feed efficiency. Moreover, with the exception of GLUT5, the expression of all sugar, peptide, and amino acid transporters was significantly downregulated in the birds under Pb induced oxidative stress. Exposure to Pb also upregulated the antioxidant enzymes gene expression together with the downregulation of glutathione S-transferase and Hsp70. In conclusion, it appears that Pb-induced oxidative stress adversely suppresses feed efficiency and growth performance in chicken and the possible underlying mechanism for such phenomenon is downregulation of major nutrient transporter genes in small intestine.

scholarly journals Alleviating Effects of Vitamins C and E Supplementation on Oxidative Stress, Hematobiochemical and Histopathological Alterations Caused by Copper Toxicity in Broiler Chickens

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1739
Author(s):  
Mohamed A. Hashem ◽  
Sahar S. Abd El Hamied ◽  
Eman M. A. Ahmed ◽  
Shimaa A. Amer ◽  
Aziza M. Hassan
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Vitamin C ◽  
Broiler Chickens ◽  
Copper Toxicity ◽  
Basal Diet ◽  
High Serum ◽  
Control Group ◽  
Broiler Chicks ◽  
High Doses

The current investigation evaluated the alleviating effects of vitamin C and vitamin E on oxidative stress, hematobiochemical, and histopathological changes in the kidney induced by copper sulfate (CuSO4) toxicity in chickens. Two hundred and fifty-one-day-old male broiler chicks were randomly allotted into five experimental groups (five replicates/group, ten chicks/replicate): 1st group—basal diet with no additives (control group), 2nd group—basal diet complemented with CuSO4 (300 mg/kg diet), 3rd group—basal diet with CuSO4 (300 mg/kg diet) + vitamin C (250 mg/kg diet), 4th group—basal diet with CuSO4 (300 mg/kg diet) + vitamin E (250 mg/kg diet), and 5th group—basal diet with CuSO4 (300 mg/kg diet) + vitamin C (250 mg/kg diet) + vitamin E (250 mg/kg diet) for a 42 day feeding period. The results showed a significant reduction in red blood cells (RBCs), hemoglobin (Hb) concentration, and hematocrit values as well as total leukocyte counts (WBCs), lymphocyte, heterophil, and monocyte counts in the CuSO4-intoxicated birds (2.42 × 106/µL, 9.54 g/dL, 26.02%, 15.80 × 103/µL, 7.86 × 103/µL, 5.26 × 103/µL, and 1.18 × 103/µL, respectively, at the 6th week) compared to (2.79 × 106/µL, 10.98 g/dL, 28.46%, 21.07 × 103/µL, 10.84 × 103/µL, 7.12 × 103/µL, and 1.60 × 103/µL, respectively) in the control group. Moreover, CuSO4-intoxicated birds showed hypoglycemia with a rise in serum uric acid and creatinine levels (122.68, 5.18, and 0.78 mg/dL at the 6th week) compared to (159.46, 4.41, and 0.61 mg/dL) in the control group. The CuSO4 toxicity in birds induced oxidative stress, indicated by a high serum malondialdehyde level (MDA) and diminished activity of the antioxidant enzymes (glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD)) (2.01 nmol/mL, 37.66 U/mL, and 2.91 U/mL, respectively, at the 6th week) compared to (1.34 nmol/mL, 57.00 U/mL, 4.99 U/mL, respectively) in the control group. High doses of Cu exposure caused severe microscopic alterations in kidney architecture. The addition of vitamins C and E, singularly or in combination, displayed a beneficial effect in alleviating these harmful effects of Cu toxicity. These findings showed the possible mitigating impacts of dietary antioxidants on the hematobiochemical alterations, oxidative stress, and kidney damage induced by CuSO4 toxicity.

Phytogenics (Lemon and orange peels) influenced the performance, gut morphology and blood profile of broiler chickens

2020 ◽  
Vol 47 (3) ◽  
pp. 234-244
Author(s):  
A. O. Fafiolu ◽  
J. O. Alabi ◽  
C. G. Godwin ◽  
I. D. Dada ◽  
A. A. Orimogunje ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Growth Performance ◽  
Broiler Chickens ◽  
Haemoglobin Concentration ◽  
Basal Diet ◽  
Feed Additives ◽  
Control Group ◽  
Broiler Chicks ◽  
Blood Profile ◽  
Gut Morphology

This study evaluated the effect of phytogenic feed additives (Lemon peel, LP and Orange peel, OP) added singly or in combination to basal diets on the performance, gut morphology, haematology, serum biochemistry and lipid profile of broiler chickens. Four nutritionally adequate Corn-Soybean based diets were generated by the addition of LPand/or OPto basal diet. A total of 320, 1-d-old Marshall strain broiler chicks were given the basal diet supplemented with no additive (T1), 500g/tonne of LP (T2), OP (T3), or LP+OP (T4) in a study which lasted for 42 days. Growth performance was assessed weekly while gut and blood samples were collected at d 42 for examination. Data generated were analyzed using ANOVA with a P<0.05 level of significance. Results showed that chickens fed diets supplemented with LP and OP had similar (P>0.05) growth performance compared with the control group. Higher (P<0.05) duodenal and jejunal villus height were observed in chickens fed LP and OP, respectively. Phytogenics inclusion caused reduced (P<0.05) laminal propria depth at the ileum segment. Higher (P<0.05) PCV (30.00%), total protein (6.89 g/L) and albumin (3.67 g/L) were observed in chickens on LP+OP. Haemoglobin concentration (Hb) and RBC were not affected by the treatments imposed. Serum creatinine, uric acid and liver enzymes (AST and ALT) activity were reduced (P<0.05) with inclusion of LP and OP in broiler diets. Increase (P<0.05) HDL and decrease total cholesterol, LDL and triglycerides were observed in broilers fed LP and OP. Dietary inclusion of LP and OP had positive influence on gut morphology, RBC production, plasma protein reserves and lipid profile of broiler chickens.

Evaluation of turmeric extract on performance indices impressed by induced aflatoxicosis in broiler chickens

2011 ◽  
Vol 27 (10) ◽  
pp. 956-960 ◽  
Author(s):  
Nader Rangsaz ◽  
Majid Gholami Ahangaran
Keyword(s):  
Body Weight ◽  
Broiler Chickens ◽  
Body Weight Gain ◽  
Curcuma Longa ◽  
Basal Diet ◽  
Control Group ◽  
Broiler Chicks ◽  
Feed Conversion ◽  
Performance Indices ◽  
Turmeric Extract

The purpose of this study was evaluation of ethanolic turmeric extract (ETE; Curcuma longa) effect on overall performance including body weight (BW), body weight gain (BWG), feed intake and feed conversion ratio (FCR) weekly and cumulative for a period of 4 weeks with 300 commercial broiler chicks (Ross strain). These chicks were randomly divided into four groups with three replicates of 15 chicks in each replicate. In group A, chickens were fed a basal diet, in group B, chickens were fed a basal diet plus 3 ppm productive aflatoxin. In group C, chickens consumed a basal diet plus 0.05% ETE and in group D, chickens received a basal diet with 0.05% ETE plus 3 ppm productive aflatoxin. Aflatoxin production by Aspergillus parasiticus (PTTC NO:1850) in maize was according to the Shotwell method. The results revealed that there were no significant differences in BW, BWG and FCR between groups fed turmeric at 0.05% and the control group. The supplement of ETE in a diet containing 3 ppm aflatoxin can significantly improve performance indices compared with the group that consumed aflatoxin alone. In conclusion, our results suggest that turmeric extract ( Curcuma longa) can provide protection against the negative effects of aflatoxin on performance of broiler chickens.

scholarly journals Supplementation of probiotics in water beneficial growth performance, carcass traits, immune function, and antioxidant capacity in broiler chickens

2021 ◽  
Vol 16 (1) ◽  
pp. 311-322
Author(s):  
Lihuan Zhang ◽  
Ruonan Zhang ◽  
Hao Jia ◽  
Zhiwei Zhu ◽  
Huifeng Li ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Immune Function ◽  
Growth Performance ◽  
Broiler Chickens ◽  
Carcass Traits ◽  
Basal Diet ◽  
Bursa Of Fabricius ◽  
Daily Weight Gain ◽  
Broiler Chicks ◽  
Feed Conversion

Abstract This study aims to investigate the effects of commercial probiotic supplementation in water on the performance parameters, carcass traits, immune function, and antioxidant capacity of broiler chicks. In the experiment, 120 Arbor Acres (AA) broilers (60 male and 60 female) were randomly allocated into four groups (G) – G1: basal diet and G2, G3, and G4: basal diet with 1% Lactobacillus casei, 1% L. acidophilus, and 1% Bifidobacterium in the water, lasting 42 days. The experimental results revealed that probiotic additives produced positive impacts on body weight, average daily feed intake (ADFI), and average daily weight gain for female chicks, whereas these probiotics significantly reduced ADFI and the feed conversion ratio of male chicks (P < 0.05). Probiotics efficiently improved eviscerated yield and breast yield while reducing the abdominal fat (P < 0.05) for the male broiler chicks. A marked increase was observed in the weight of the spleen, bursa of Fabricius, and thymus in the treatment group (P < 0.05). Besides, probiotics produced a significant effect on the concentrations of immune-related proteins (P < 0.05) and markedly increased the concentrations of antioxidase and digestive enzymes when compared with the control (P < 0.05). The addition of probiotics dramatically reduced the total counts of Escherichia coli and Salmonella and increased the quantity of Lactobacilli (P < 0.05). The results of the present study demonstrated an increase in growth performance, carcass traits, immune function, gut microbial population, and antioxidant capacity by supplementing 1% probiotics (L. casei, L. acidophilus, and Bifidobacterium) in the water for broilers.

scholarly journals Effect of Broilers Chicken Diet Supplementation with Natural and Acidified Humic Substances on Quality of Produced Breast Meat

Animals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 1087
Author(s):  
Marek Hudák ◽  
Boris Semjon ◽  
Dana Marcinčáková ◽  
Lukáš Bujňák ◽  
Pavel Naď ◽  
...  
Keyword(s):  
Lipid Oxidation ◽  
Humic Substances ◽  
Broiler Chickens ◽  
Storage Period ◽  
Basal Diet ◽  
Control Group ◽  
Total Protein Content ◽  
Breast Meat ◽  
Broiler Diet

This study was conducted to examine the effect of two humic substances (HS) supplemented in broilers’ diet on the breast meat quality of broiler chickens. In this experiment, 120 pieces of one-day-old COBB500 broiler chickens were used. Broilers were divided into three groups, each containing 40 birds with three replications (13, 13, and 14 per one pen). Fattening lasted 38 days. The first experimental diet was supplemented with 0.7% of HS (HS0.7) and the second was enriched with 0.7% of acidified HS (HSA0.7). The control group of broilers (C) was fed a basal diet without the addition of any supplements. HS0.7 samples had the highest total protein content and the lowest content of fat (p < 0.01). The effects of broiler diet and storage had a significant impact on the pH of breast samples, p < 0.001 and p < 0.05, respectively. Supplementation of HS in broiler diet positively affected the lipid oxidation of breast meat samples, as indicated by the lower malondialdehyde content (p < 0.05). HSA0.7 samples had significantly better juiciness after the storage period (p < 0.001). The quality of meat produced with supplementation of HS in broilers’ feed can be considered as valuable in human nutrition due to improved protein and fat content with decreased lipid oxidation.

scholarly journals Growth Performance, Nutrient Digestibility, Biochemical Properties, Hematological Traits, and Intestinal Histopathology of Broiler Chicks Fed Mannan Oligosaccharides

2021 ◽  
Vol 11 (4) ◽  
pp. 621-633
Author(s):  
Abdallah Ali Ghazalah ◽  
Mohamed Ahmed Fouad El-Manylawi ◽  
Hady Fathy Abbas Motawe ◽  
Marwa Salah Khattab ◽  
Yara Ibrahem Youssef
Keyword(s):  
Growth Performance ◽  
Broiler Chickens ◽  
Density Lipoprotein ◽  
Basal Diet ◽  
Blood Parameters ◽  
Nutrient Digestibility ◽  
The Other ◽  
Control Group ◽  
Broiler Chicks ◽  
Treatment Groups

, , , , and Antibiotics as growth promoters in poultry diets are currently restricted, so other feed additives, such as prebiotics and probiotics, have been suggested as an antibiotics alternative to improve the performance and gut health of poultry. The current experiment was conducted to study the effects of adding Mannan oligosaccharides (MOS) as a potential replacement for an antibiotic on productive performance, nutrient digestibility, some blood parameters, and caecal microbiota of broiler chickens. For conducting the current research experiment, a total of 180 one–day old Ross broiler chicks were randomly divided into one control group fed a basal diet and four dietary treatments with six replicates for each treatment. The treatment groups were fed a basal diet supplemented with different levels of MOS 0.5, 1, and 2 g/Kg diet and Lincomycin 4.4 mg/Kg diet during 35 days of the feeding trial. With exception of the growing period, the group fed a basal diet supplemented with 2 g MOS/Kg feed had considerably higher body weight and weight gain, while having the lowest feed consumption and best feed conversion ratio compared to the other treatment groups, during all experimental periods. Moreover, dietary supplementation of MOS resulted in a significant decrease in the counts of caecal E. coli and Enterococcus, while Lactobacillus and Yeast bacteria counts were significantly higher, compared to non-supplemented groups. Broiler chicks having a 2 g MOS/kg diet recorded lower values of cholesterol, low-density lipoprotein (LDL), urea, and liver enzymes, including Aspartate transaminase (AST) and Alanine aminotransferase (ALT), while they recorded significantly higher high-density lipoprotein (HDL), compared to the other experimental groups. Group treated with MOS 2 g/Kg feed improved digestibility of crude protein, ether extract, crude fiber, nitrogen-free extract, and organic matter, compared to the control group, Additionally, MOS supplementation also increased the intestinal villi length, width, and crypt depth and decreased intestinal inflammation, compared to the control group. In conclusion, supplementation of MOS at 2 g/kg diet improved growth performance, digestibility, and blood parameters without having adverse effects on the intestine of broiler chickens, comparable to the Lincomycin.

scholarly journals Effects of perch availability on performance, carcass characteristics, and footpad lesions in broilers

2016 ◽  
Vol 59 (1) ◽  
pp. 19-25 ◽  
Author(s):  
Z. Kiyma ◽  
K. Küçükyılmaz ◽  
A. Orojpour
Keyword(s):  
Growth Performance ◽  
Broiler Chickens ◽  
Production Systems ◽  
Carcass Characteristics ◽  
Control Group ◽  
Broiler Chicks ◽  
Meat Color ◽  
Breast Meat ◽  
Positive Effects ◽  
Positive Effect

Abstract. In the modern broiler industry, solutions are still being sought to improve conditions or eliminate problems related to issues such as animal welfare, health, and meat quality brought by intensive production systems. Therefore, this experiment was conducted to study effects of perching on growth performance, carcass characteristics, and footpad lesions (FPLs) in broiler chickens. A total of 300 broiler chicks (Ross 308) were distributed into control and perch groups with three replicates including equal numbers of males and females. The perch group contained two single perches in each pen. Analysis of camera records revealed that on average 7.36 % of the birds using perches. Perch use did not have any effect on growth performance (P  >  0.05), but had a positive effect on FPLs (P  <  0.001). Carcass yield and proportions of carcass parts were not affected by perch availability (P  >  0.05). Thigh and breast meat color was less yellow (P  <  0.005) in the perch group compared to the control group, where breast meat color was more red (P  <  0.01). Birds in the perch group had brighter breast meat (P  <  0.001). The weight of livers in the perch group was lower than in the control group (P  <  0.01). These findings suggest that perch use has positive effect on FPLs. The reduction of redness in the breast could indicate that perch use may have a positive effect on breast inflammation. The potential positive effects of adapting perch use to intensive conditions should be further investigated.

scholarly journals Effect of Dietary Ginger (Zingiber officinale Roscoe) and Multi-Strain Probiotic on Growth and Carcass Traits, Blood Biochemistry, Immune Responses and Intestinal Microflora in Broiler Chickens

Animals ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. 117 ◽  
Author(s):  
Mehdi Qorbanpour ◽  
Taha Fahim ◽  
Faramin Javandel ◽  
Mehran Nosrati ◽  
Erwin Paz ◽  
...  
Keyword(s):  
Broiler Chickens ◽  
Growth Traits ◽  
Control Diet ◽  
Basal Diet ◽  
Zingiber Officinale ◽  
Blood Biochemistry ◽  
Control Group ◽  
Broiler Chicks ◽  
Randomized Design ◽  
Dietary Treatments

A total of 225 day-old male broiler chicks (Ross-308) were randomly allocated to five treatment groups, with three replicates in a completely randomized design for 42 days. Birds were fed a basal-diet supplemented with: no additive (control-diet), multi-strain probiotic (Lactobacillus acidophilus, Lactobacillus casei, Enterococcus faecium and Bifidobacterium thermophilum), or 0.15, 0.20 and 0.25% ginger (Z. officinale) powder, respectively. The results show no significant differences among treatments for growth traits and carcass characteristics, whereas using probiotics and ginger at all levels resulted in a significant decrease of gizzard weight and abdominal fat compared to the control group. Dietary treatments did not affect blood biochemistry and antibody production against sheep red blood cells (SRBC), IgG and IgM; however, antibody titre was higher in birds fed 0.25% ginger than other diets after 7 days post injection. The Lactobacillus counts in ileal content of birds fed 0.20 and 0.25% ginger were higher compared to the other treatments. In conclusion, dietary supplementation with either ginger or probiotics showed a significant influence on birds’ immune response, probably because ginger had strong antioxidant activity and the probiotics stimulated the production of natural antibodies.

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