The relationship between Elevated Body Mass Index, Exhaled Nitic Oxide, Vitamin D Serum Concentration and Asthma Control – the Cross-sectional Pilot Study

Abstract The β3-adrenergic receptor (ADRB3) is expressed mainly in visceral adipose tissue and is thought to contribute to lipolysis and the delivery of free fatty acids to the portal vein. Although many studies have examined the relationship between the Trp64Arg mutation of ADRB3 and obesity, the results have been inconsistent. We examined the cross-sectional relationship of ADRB3 variants with indexes of obesity, and their longitudinal changes over 10 yr, in men and women, aged 40–69 yr, who were randomly selected from the Japanese rural population. The study considered both dietary energy intake and physical activity levels. Among the 746 participants, the genotype frequencies of the Trp64Trp, Trp64Arg, and Arg64Arg variants were 483, 224, and 39, respectively. The cross-sectional analysis showed no significant differences in height, weight, body mass index, blood pressure, serum total and high density lipoprotein cholesterols, and hemoglobin A1c among the genotype groups even after adjustments for gender, age, smoking, alcohol drinking, physical activity, and energy intake. No significant differences in the weight changes between the genotype groups were evident in the longitudinal analysis. We conclude that the Trp64Arg mutation of ADRB3 has little or no influence on either body weight or body mass index in the general Japanese population.

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The relationship of body mass index to penile length and testicular volume in adolescent boys

Paediatrica Indonesiana ◽

10.14238/pi52.5.2012.267-71 ◽

2012 ◽

Vol 52 (5) ◽

pp. 267

Author(s):

Rizky Adriansyah ◽

Muhammad Ali ◽

Hakimi Hakimi ◽

Melda Deliana ◽

Siska Mayasari Lubis

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Junior High School ◽

Testicular Volume ◽

Adolescent Boys ◽

Penile Length ◽

School Students ◽

Cross Sectional ◽

Relationship Of ◽

The Relationship

Background Evidence suggests that obesity may be related toearly onset of puberty in girls. However, few studies have found alink between body mass index (BMI) and puberty onset in boys.More study is needed to assess the relationship of BMI to penilelength and testicular volume.Objective To investigate the relationship ofBMI to penile lengthand testicular volume in adolescent boys.Methods A cross􀀿sectional study was carried out on adolescentboys aged 9 to 14 years in Secanggang District, Langkat Regency,North Sumatera Province in August 2009. Subjects' BMIs werecalculated by dividing body weight (BW) in kilograms by bodyheight (BH) in meters squared. Penile length (em) was measuredwith a spatula. We took the average of three measurements fromthe symphysis pubis to the tip of the glans penis. Testicular volume(mL) was estimated by palpation using an orchidometer. Pearson'scorrelation test (r) was used to assess the relationship of BMI topenile length and BMI to testicular volume.Resu lts There were 108 participants, consisting of 64primary school students and 44 junior high school students.Subjects' mean age was 11.7 (SO 1.62) years; mean BWwas 35.2 (SO 8.48) kg; mean BH was 1.4 (SO 0.11) m;mean BMI was 17.5 (SO 2.34) kg/m'; mean penile lengthwas 4.5 (SO 1.25) cm; and mean testicular volume was 3.6(SD 1.20) mL. We found no significant association betweenBMI and penile length (r􀀻-0.25, P􀀻0.06), nor betweenBMI and testicular volume (r􀀻-O.21; P􀀻O.09).Conclusion T here was no significant relationship ofBMI to penilelength nor BMI to testicular volume in adolescent boys.[Paediatr lndanes. 2012;52:267-71].

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Pubertal Stage, Body Mass Index, and Cardiometabolic Risk in Children and Adolescents in Bogotá, Colombia: The Cross-Sectional Fuprecol Study

Nutrients ◽

10.3390/nu9070644 ◽

2017 ◽

Vol 9 (7) ◽

pp. 644 ◽

Cited By ~ 7

Author(s):

Robinson Ramírez-Vélez ◽

Antonio García-Hermoso ◽

Cesar Agostinis-Sobrinho ◽

Jorge Mota ◽

Rute Santos ◽

...

Keyword(s):

Body Mass Index ◽

Children And Adolescents ◽

Body Mass ◽

Cardiometabolic Risk ◽

Pubertal Stage ◽

Cross Sectional ◽

The Cross

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The Relationship between Body Mass Index, Obesity, and LINE-1 Methylation: A Cross-Sectional Study on Women from Southern Italy

Disease Markers ◽

10.1155/2021/9910878 ◽

2021 ◽

Vol 2021 ◽

pp. 1-7

Author(s):

Andrea Maugeri ◽

Martina Barchitta ◽

Roberta Magnano San Lio ◽

Giuliana Favara ◽

Claudia La Mastra ◽

...

Keyword(s):

Body Mass Index ◽

Dna Methylation ◽

Body Mass ◽

Methylation Level ◽

Molecular Mechanisms ◽

Smoking Status ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

The Relationship

Uncovering the relationship between body mass index (BMI) and DNA methylation could be useful to understand molecular mechanisms underpinning the effects of obesity. Here, we presented a cross-sectional study, aiming to evaluate the association of BMI and obesity with long interspersed nuclear elements (LINE-1) methylation, among 488 women from Catania, Italy. LINE-1 methylation was assessed in leukocyte DNA by pyrosequencing. We found a negative association between BMI and LINE-1 methylation level in both the unadjusted and adjusted linear regression models. Accordingly, obese women exhibited lower LINE-1 methylation level than their normal weight counterpart. This association was confirmed after adjusting for the effect of age, educational level, employment status, marital status, parity, menopause, and smoking status. Our findings were in line with previous evidence and encouraged further research to investigate the potential role of DNA methylation markers in the management of obesity.

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The Relationship Between Body Mass Index and Pain Intensity Among Veterans with Musculoskeletal Disorders: Findings from the MSD Cohort Study

Pain Medicine ◽

10.1093/pm/pnaa043 ◽

2020 ◽

Vol 21 (10) ◽

pp. 2563-2572 ◽

Cited By ~ 1

Author(s):

Diana M Higgins ◽

Eugenia Buta ◽

Alicia A Heapy ◽

Mary A Driscoll ◽

Robert D Kerns ◽

...

Keyword(s):

Body Mass Index ◽

Pain Intensity ◽

Body Mass ◽

Negative Binomial ◽

Low Back ◽

Veterans Health ◽

Health Administration ◽

Electronic Health Record Data ◽

Cross Sectional ◽

The Relationship

Abstract Objective To examine the relationship between body mass index (BMI) and pain intensity among veterans with musculoskeletal disorder diagnoses (MSDs; nontraumatic joint disorder; osteoarthritis; low back, back, and neck pain). Setting Administrative and electronic health record data from the Veterans Health Administration (VHA). Subjects A national cohort of US military veterans with MSDs in VHA care during 2001–2012 (N = 1,759,338). Methods These cross-sectional data were analyzed using hurdle negative binomial models of pain intensity as a function of BMI, adjusted for comorbidities and demographics. Results The sample had a mean age of 59.4, 95% were male, 77% were white/Non-Hispanic, 79% were overweight or obese, and 42% reported no pain at index MSD diagnosis. Overall, there was a J-shaped relationship between BMI and pain (nadir = 27 kg/m2), with the severely obese (BMI ≥ 40 kg/m2) being most likely to report any pain (OR vs normal weight = 1.23, 95% confidence interval = 1.21–1.26). The association between BMI and pain varied by MSD, with a stronger relationship in the osteoarthritis group and a less pronounced relationship in the back and low back pain groups. Conclusions There was a high prevalence of overweight/obesity among veterans with MSD. High levels of BMI (>27 kg/m2) were associated with increased odds of pain, most markedly among veterans with osteoarthritis.

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Consumption Frequency of Foods Away from Home Linked with Higher Body Mass Index and Lower Fruit and Vegetable Intake among Adults: A Cross-Sectional Study

Journal of Environmental and Public Health ◽

10.1155/2016/3074241 ◽

2016 ◽

Vol 2016 ◽

pp. 1-12 ◽

Cited By ~ 51

Author(s):

Rebecca A. Seguin ◽

Anju Aggarwal ◽

Francoise Vermeylen ◽

Adam Drewnowski

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Vegetable Intake ◽

Cross Sectional Study ◽

Fruit And Vegetable ◽

Cross Sectional ◽

Adult Men ◽

Consumption Frequency ◽

Eating Out ◽

The Relationship

Introduction. Consumption of foods prepared away from home (FAFH) has grown steadily since the 1970s. We examined the relationship between FAFH and body mass index (BMI) and fruit and vegetable (FV) consumption.Methods. Frequency of FAFH, daily FV intake, height and weight, and sociodemographic data were collected using a telephone survey in 2008-2009. Participants included a representative sample of 2,001 adult men and women (mean age54±15years) residing in King County, WA, with an analytical sample of 1,570. Frequency of FAFH was categorized as 0-1, 2–4, or 5+ times per week. BMI was calculated from self-reported height and weight. We examined the relationship between FAFH with FV consumption and BMI using multivariate models.Results. Higher frequency of FAFH was associated with higher BMI, after adjusting for age, income, education, race, smoking, marital status, and physical activity (women:p=0.001; men:p=0.003). There was a negative association between frequency of FAFH and FV consumption. FAFH frequency was significantly (p<0.001) higher among males than females (43.1% versus 54.0% eating out 0-1 meal per week, resp.). Females reported eating significantly (p<0.001) more FV than males.Conclusion. Among adults, higher frequency of FAFH was related to higher BMI and less FV consumption.

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