scholarly journals The Patent Fact about Alcohol and Getting Stroke: A Case Control Study

Healthline ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 28-32
Author(s):  
Kuntalkumar H Patel ◽  
Shreyashkumar Gandhi ◽  
Dhruti Vaidya
Keyword(s):  
Case Control Study ◽  
Sample Size Calculation ◽  
Vascular Diseases ◽  
Tertiary Hospital ◽  
Case Control ◽  
World Health ◽  
Heart Attacks ◽  
Study Results ◽  
Health Organization ◽  
Control Study

Introduction: Globally 17.9 million people die each year from CVDs (Cardio Vascular Diseases) and 85% of all CVD deaths are due to heart attacks and strokes. According to the World Health Organization (WHO), 15 million people worldwide suffer from stroke every year and after ischemic heart disease, stroke is the second most leading cause of death. Objective: To study alcohol consumption as a risk factor in patients with acute strokes. Method: Case control study was conducted among 148 newly diagnosed cases of CT scan / MRI-confirmed stroke and 148 non-stroke controls attending the tertiary hospital of central Gujarat. Sample size calculation was done, assuming the power ratio of the number of controls same as numbers of cases i.e.,1:1, specifying values for two-sided confidence level=95% (error=5%), power of study=80%, odd ratio=2.15, percent of cases with exposure=82% and percent of controls with exposure=68%. Patients who are willing to participate in the study were included. The data were analyzed using the EPI INFO TM 7.0.8.0 software. Results: Out of the total 148 cases, 100 (67.56 per cent) were male and 48 (32.43 per cent) were female. The odds of getting stroke among alcoholic was two times more as compared to non-alcoholic patients. Heavy alcohol drinkers have a significant association. Conclusion: According to the study results male married patients who drank heavily had a higher risk of stroke than light/moderate alcoholics.

FAKTOR - FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN PREEKLAMSIA BERAT PADA IBU BERSALIN DI RS. MUHAMMADIYAH PALEMBANG TAHUN 2013

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Martina Astari Martina Astari
Keyword(s):  
World Health Organization ◽  
Educational Level ◽  
Maternal Age ◽  
Case Control Study ◽  
Case Control ◽  
Severe Preeclampsia ◽  
World Health ◽  
P Value ◽  
Health Organization ◽  
Control Study

ABSTRACT According to the World Health Organization (WHO 2010) approximately 99% of cases of maternal deaths occur during labor and postpartum. One of the causes of maternal death due to preeclampsia. Country - developing countries maternal mortality rate of 450 / 100,000 live births, this is a very high number. In the hospital Palembang obtained Muhammaddiyah severe preeclampsia incidence by 2013 as many as 85 cases. Many things that cause severe preeclampsia include maternal age, parity, educational level, employment. The purpose of this study was to determine the relationship of maternal age, parity, educational level, work simultaneously with perinatal death. This type of research is a case control study conducted retrospectively. The population in this study were all women giving birth in hospital Muhammadiyah Palembang in the year 2013 that berjumlah2565. The study sample totaled 225 respondents. In this study conducted univariate, bivariate and multivariate analyzes. From the analysis we found no association with maternal age incidence of severe preeclampsia (P Value 0.043 OR 1.799), no parity relationship with the incidence of severe preeclampsia (P Value 0.010 OR 0.617), no correlation with the incidence rate of severe preeclampsia education (P Value 0.027 OR 1.394) , there is a relationship how to work with the incidence of severe preeclampsia (P Value 0.024 OR 0.576), the most dominant variable is the age of the mother. It is suggested to the leadership of Muhammadiyah hospital Palembang is hoped to be able to further improve health care programs for women giving birth so as to prevent the occurrence of complications during labor and to increase outreach programs about the importance of prenatal care and provide knowledge about the complications - complications during childbirth to facilitate the birth process. References       : 16 (2002-2013)     ABSTRAK Menurut World Health Organization (WHO 2010) sekitar 99 % kasus kematian ibu terjadi pada masa persalinan dan pasca persalinan. Salah satu penyebab kematian ibu karena preeklamsia. Dinegara – negara berkembang angka kematian ibu sebesar 450/100.000 kelahiran hidup, ini merupakan angka yang sangat tinggi. Di Rumah Sakit Muhammaddiyah Palembang didapatkan kejadian preeklamsia berat pada tahun 2013 sebanyak 85 kasus. Banyak hal yang menyebabkan preeklamsia berat diantaranya umur ibu, paritas, tingkat pendidikan, pekerjaan. Tujuan penelitian ini untuk mengetahui hubungan umur ibu, paritas, tingkat pendidikan, pekerjaan secara simultan dengan kematian perinatal. Jenis penelitian ini merupakan penelitian case control study yang dilakukan secara retrospektif. Populasi dalam penelitian ini adalah semua ibu bersalin di rumah sakit Muhammadiyah Palembang pada Tahun 2013 yang berjumlah2565. Sampel penelitian ini berjumlah 225 responden. Dalam penelitian ini dilakukan analisis univariat, bivariat dan multivariat. Dari hasil analisis didapatkan ada hubungan umur ibu dengan kejadian preeklamsia berat (P Value 0,043 OR 1,799), ada hubungan paritas dengan kejadian preeklamsia berat (P Value 0,010 OR 0,617), ada hubungan tingkat pendidikan dengan kejadian preeklamsia berat (P Value 0,027 OR 1,394), ada hubungan cara pekerjaan dengan kejadian preeklamsia berat (P Value 0,024 OR 0,576), Variabel paling dominan adalah umur ibu. Disarankan kepada pimpinan rumah sakit Muhammadiyah Palembang Diharapkan untuk dapat lebih meningkatkan program pelayanan kesehatan kepada ibu bersalin sehingga  mencegah terjadinya komplikasi selama persalinan serta meningkatkan program penyuluhan tentang pentingnya pemeriksaan kehamilan  dan memberikan pengetahuan mengenai komplikasi – komplikasi selama masa persalinan untuk memperlancar proses persalinan.

scholarly journals Faktor Risiko Kejadian COVID-19 Pada Pasien Di RSUD Sayang Rakyat Kota Makassar

2022 ◽  
pp. 1487-1497
Author(s):  
Wa Ode Nurfalah ◽  
Nur Ulmy Mahmud ◽  
Sumiaty ◽  
Mansur Sididi ◽  
Nurul Hikmah
Keyword(s):  
World Health Organization ◽  
Case Control Study ◽  
Case Control ◽  
World Health ◽  
Health Organization ◽  
Control Study

COVID-19 adalah penyakit menular yang baru ditemukan pada Desember 2019 di Wuhan yang disebabkan oleh SARS-CoV-2. Mulai januari 2020, virus ini menyebar ke luar Tiongkok, pertama di Thailand, Korea Selatan, dan Jepang. Sehingga pada tanggal 11 Maret 2020 World Health Organization (WHO) menyatakan COVID-19 sebagai pandemi. COVID-19 pertama dilaporkan di Indonesia pada tanggal 2 Maret 2020 sejumlah 2 kasus. Virus ini dapat menyerang siapa saja, baik balita, anak-anak, orang dewasa, orang tua, ibu hamil maupun ibu yang sedang menyusui. Namun, beberapa orang memiliki risiko lebih tinggi untuk terinfeksi COVID-19. Tujuan dari penelitian ini untuk mengetahui faktor risiko kejadian COVID-19 pada pasien COVID-19 di Rumah Sakit Umum Daerah (RSUD) Sayang Rakyat Kota Makassar. Jenis penelitian ini adalah observasional analitik dengan rancangan Case Control study. Hasil penelitian ini menunjukan bahwa umur merupakan faktor risiko yang tidak bermakna terhadap kejadian COVID-19 dengan nilai OR=6,556 95% CI 0,764-56,219. Kebiasaan merokok merupakan faktor risiko yang bermakna terhadap kejadian COVID-19 dengan nilai OR=1,447 95% CI 1,447-15,046. Kontak erat merupakan faktor risiko yang bermakna terhadap kejadian COVID-19 dengan nilai OR=188,500 95% CI 38,284-928,114. Komorbid merupakan faktor risiko yang bermakna terhadap kejadian COVID-19 dengan nilai OR=3,406 95% CI 1,486-7,809.  Sebagai saran dalam penelitian ini masyarakat diharapkan untuk mengkonsumsi makanan yang dapat meningkatkan imun tubuh, mengurangi atau bahkan berhenti merokok, selalu mematuhi protokol kesehaatan serta bagi masyarakat yang memiliki komorbid diharapkan dapat mengendalikan komorbidnya.

Lymphocyte-to-monocyte ratio in predicting the calcific aortic valve stenosis in a Chinese case–control study

2020 ◽  
Vol 14 (14) ◽  
pp. 1329-1339
Author(s):  
Xiaochun Ma ◽  
Huibo Ma ◽  
Yan Yun ◽  
Shanghao Chen ◽  
Xiaofeng Zhang ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Stenosis ◽  
Case Control Study ◽  
Independent Predictor ◽  
Inverse Correlation ◽  
Case Control ◽  
Lymphocyte To Monocyte Ratio ◽  
Study Results ◽  
Chinese Case ◽  
Control Study

Aim: This study examined the role of lymphocyte-to-monocyte ratio (LMR), an inflammatory biomarker, in predicting the severity of calcific aortic valve stenosis (CAVS) in a Chinese case–control study. Results: The LMR significantly decreased in the patients with CAVS compared with healthy controls. An inverse correlation was observed between the severity of stenosis and LMR in the patients. Additionally, the LMR was identified in the multivariate analysis as an independent predictor of severe CAVS. Conclusion: This study provides evidence of an inverse correlation between the severity of CAVS and LMR. LMR could potentially be applied as an independent predictor of severe CAVS and could be incorporated into a novel predictive model.

scholarly journals 745 Risk Factors of Incident Renal Stones in Indian Population: A Hospital-Based Case-Control Study

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
S Singh ◽  
S Gupta ◽  
T S Mishra ◽  
B D Banerjee ◽  
T Sharma ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heavy Metals ◽  
Case Control Study ◽  
Dietary Habits ◽  
Renal Stones ◽  
Tertiary Hospital ◽  
Case Control ◽  
The Body ◽  
Increased Risk ◽  
Control Study

Abstract Introduction Nephrolithiasis is pathological calcification in the excretory passages of the body and is prevalent among 7.6% of Indians. We aimed to study the various risk factors associated with renal stones from India. Method It was a hospital-based case-control study conducted over 18 months in a tertiary hospital in Delhi. Cases were defined as patients with renal stones diagnosed on the basis of history and radiological examination. Controls were similar to cases in all respects except for the diagnosis and selected from the hospital. A total of 18 risk factors, including age, gender, heavy metals, stress, metabolic factors, alcohol intake, dietary habits, co-morbidities, etc. were assessed. Logistic regression analysis was performed to calculate the strength of the risk associations. Results In the analysis of 60 cases and controls, we found 6 times, 5.5 times, and 2.4 times increased odds of renal stones in patients with increased arsenic, cadmium, and lead concentrations in blood, respectively. Similarly, there are 3 times increased odds of renal stones in patients suffering from stress. Conclusions Exposure to smoke, occupation dust, and contaminated water may lead to an increased ingestion/inhalation of heavy metals like cadmium, arsenic, and predisposing people to an increased risk of renal stones.

scholarly journals Influenza A (H1N1) virus infection and TNF-308, IL6, and IL8 polymorphisms in Egyptian population: a case–control study

2019 ◽  
Vol 80 (1) ◽  
Author(s):  
Shaimaa Moustafa Elsayed ◽  
Omayma Mohamed Hassanein ◽  
Nagwa Hassan Ali Hassan
Keyword(s):  
Influenza A ◽  
Case Control Study ◽  
H1n1 Virus ◽  
Case Control ◽  
Severe Illness ◽  
Study Results ◽  
Influenza A H1n1 ◽  
Pandemic Strains ◽  
Study Participants ◽  
Control Study

Abstract Background The importance of influenza is increasing mainly because of the appearance of novel pandemic strains such as swine and avian. Each year, influenza has spread around the world causing about 250,000–500,000 deaths and more than 5 million cases of severe illness. The objective is as follows: evaluating the outcomes of patients with influenza A (H1N1) virus in relation to certain TNF-308, IL6, and IL8 polymorphisms and identifying the associated factors with the severe outcome. Subject and methods This is a case–control study. The cases were patients confirmed by real-time polymerase chain reaction (RT-PCR) to be influenza A (H1N1) virus infected. The controls were healthy individuals. Medical history and outcome of the disease was registered. In all study participants, polymorphisms of TNF rs1800629, IL6 rs18138879, and IL8 rs4073; odds ratio (OR); and the 95% confidence interval (95% CI) were calculated. Results Infection with influenza A (H1N1) virus was associated more with the following genotypes: TNF-308 AA (OR = 4.041; 95% CI = 1.215–13.4) and IL8 AA (OR = 3.273; 95% CI = 1.372–7.805). According to our study results, HCV (OR = 3.2, 95% CI 1.2–8.5), renal disease (OR = 3.4, 95% CI 0.9–13.6), cancer (OR = 3.1, 95% CI 0.3–31.1), TB (OR = 8.4, 95% CI 1.8–39.7), ICU (OR = 2.9, 95%1.2–7.1), and mortality (OR = 7.9, 95% CI 0.9–67.4) are considered as risk factors for influenza A (H1N1)-infected patients. Conclusions Our findings concluded that TNF-308 (AA) and IL8 (AA) polymorphisms may increase the susceptibility to be infected with H1N1influenza virus.

scholarly journals High Blood Pressure during Pregnancy is not a Protective Factor for Preterm Infants with Very Low Birth Weight. A Case-Control Study

2017 ◽  
Vol 39 (04) ◽  
pp. 155-161 ◽  
Author(s):  
Annibal Sabino ◽  
Eduardo de Souza ◽  
Ana Goulart ◽  
Adriana Lima ◽  
Nelson Sass
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Protective Factor ◽  
Case Control Study ◽  
Very Low Birth Weight ◽  
Case Control ◽  
World Health ◽  
Control Group ◽  
Control Study

Objective To evaluate whether the presence of maternal blood pressure reduces the risks of morbidity, perinatal mortality and morbidity at 24 months of age in very low birth weight infants (VLBWIs) compared with a control group. Methods A retrospective, observational, case-control study. Total 49 VLBWIs were allocated to the study group, called the maternal arterial hypertension group (AHG), and matched with 44 in the control group (CG). The infants were assessed during hospitalization and at 12 and 24 months corrected age at a specialized clinic. For the assessment of growth, the World Health Organization (WHO) Anthro software (Geneva, 2006) was used, and for the psychomotor assessment, the Denver II test was used. Results In relation to the antenatal variables, the infants of the AHG had more centralized circulation assessed by Doppler, received more corticosteroids and magnesium sulfate, and were born by cesarean section more frequently. In terms of the postnatal and in-hospital outcomes, the AHG had a higher gestational age at birth (30.7 versus 29.6 weeks) and a lower frequency of 5-minute Apgar scores of less than 7 (26.5% versus 52.3%). The CG had a higher rate of pulmonary dysplasia (30.2% versus 8.3%). There were no differences in terms of hospital mortality, complications, somatic growth and functional problems at 24 months of corrected age. Conclusion The presence of maternal hypertension, especially preeclampsia, was not a protective factor against morbidity, mortality and evolution in VLBWIs aged up to 24 months. Therefore, the clinical practice should be focused on prolonging the pregnancy for as long as possible in these conditions as well.

scholarly journals Risk Factors for Herpes Zoster Infection in Patients With Chronic Kidney Disease: A Case-control Study

2021 ◽  
Author(s):  
Qiao Wang ◽  
Jiahui Ma ◽  
Zhenxing Li ◽  
Zhi Li ◽  
Dong Huang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Herpes Zoster ◽  
Kidney Disease ◽  
Odds Ratio ◽  
Case Control Study ◽  
Immunosuppressive Agents ◽  
Tertiary Hospital ◽  
Case Control ◽  
Control Study

Abstract Background: Chronic kidney disease (CKD) increases the susceptibility to the infection of herpes zoster (HZ). Less is known about the risk factors of HZ in CKD patients.Methods and Participants: This is a case-control study. CKD patients diagnosed with HZ infection between January 2015 and October 2020 in a tertiary hospital were identified. One age- and gender- matched control was paired for each case, matched to the date of initial HZ diagnose. The uni- and multivariate analysis were used to evaluate the risk factors for development of HZ in CKD patients.Results: Forty-six HZ patients and controls were identified. In general, about 80% (72 out of 92) patients were classified at end-stage renal disease (ESRD, CKD Ⅳ to Ⅴ). Multivariate analyses revealed that immunosuppressive agents (odds ratio: 12.50, 95% CI: 1.53-102.26, P=0.021) and dialysis (odds ratio: 3.33, 95% CI: 1.13-9.78, P=0.029) were independent risk factors of HZ in patient with CKD. Conclusion: Immunosuppressive medication and dialysis were associated with HZ infection in CKD. Further guideline may highlight the necessity of zoster vaccine for patients with CKD, who undertake immunosuppressive or dialysis treatment.

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