A PREPARATION FOR THE TREATMENT OF VARIOUS TYPES OF MASTITIS

2021 ◽  
Vol 1 (1) ◽  
pp. 140-144

In large dairy farms, a special place is occupied by diseases of the mammary glands, which significantly affect the productivity of animals and reduce the quality of milk. Despite the fact that much attention is paid in science and practice to the problem of the spread and prevention of breast diseases, their harm increases every year. The main method of prevention of mastitis diseases is cost-effective animal husbandry with compliance with zoohygienic requirements for keeping, feeding and milking, which ensure a high level of natural stability of the body and productivity of animals. Our proposed drug «Dorob-K» was used for the first time. The composition of the drug consists of red oil and ASD2 fraction. Red oil-polyphite oil, a medicinal product of plant origin. A complex of biologically active substances that are part of herbs (mainly saponin glycosides – glycyrrhizin, as well as essential oils, peptides, vitamins and minerals) have an anti-inflammatory, antibacterial, regenerating effect. It is a 100% natural extract made from 7 types of medicinal plants (melissa grass, thyme creeping grass, rosehip fruit, licorice roots, nettle leaves, St. John's wort grass, sea buckthorn oil) and as an auxiliary substance - sunflower oil. Sea buckthorn oil and ASD2 fraction have immunomodulating and regenerating properties. They, covering inflammatory tissues, reduce the sensitivity of nerve endings and contribute to faster healing of inflammatory processes. And ASD2 fraction is a tissue preparation that has a high therapeutic effect in the treatment of mastitis, activates the physiological processes of a healthy body and increases its resistance to various factors. The proposed drug contains natural, environmentally friendly and pharmacologically active drugs. The drug «Dorob-K» is easy to prepare and use. The prepared drug was injected into the udder of cows intracisternally, in an amount of 5 ml, 2 times a day, with an interval of 12 hours. For the treatment of latent udder, 4 days were used, and for the treatment of clinical forms-7 days.

2019 ◽  
Vol 20 (7) ◽  
pp. 661-665
Author(s):  
Cunxi Nie ◽  
Fei Xie ◽  
Ning Ma ◽  
Yueyu Bai ◽  
Wenju Zhang ◽  
...  

As a major component of biologically active compounds in the body, proteins contribute to the synthesis of body tissues for the renewal and growth of the body. The high level of dietary protein and the imbalance of amino acid (AA) composition in mammals result in metabolic disorders, inefficient utilization of protein resources and increased nitrogen excretion. Fortunately, nutritional interventions can be an effective way of attenuating the nitrogen excretion and increasing protein utilization, which include, but are not limited to, formulating the AA balance and protein-restricted diet supplementing with essential AAs, and adding probiotics in the diet. This review highlights recent advances in the turnover of dietary proteins and mammal’s metabolism for health, in order to improve protein bioavailability through nutritional approach.


Author(s):  
L. P. Yarmots ◽  
G. A. Yarmots ◽  
A. E. Belenkaya ◽  
M. O. Smyshlyaeva

Unbalanced mineral and vitamin nutrition of lactating cows can be a critical factor in the realization of their productive potential. The development and introduction into production of inexpensive, but effective feed additives is the main trend of improving the feeding of modern animal husbandry. Under the conditions of the Tyumen region such natural raw materials can be sapropels, which successfully combine a variety of biologically active substances. The purpose of the research was to study the digestibility of nutrients and energy metabolism in lactating cows when sapropel is included in the ration. Scientifi c and economic experiment in the study of the effectiveness of feeding sapropel lake Nepryak has been carried out in the training and experimental farm of the State Northern Trans-Urals Agrarian University. The animals of the control group have been fed the main diet. Cows of the 1st and 2nd experimental groups have been fed 300 and 500 g of sapropel per head/day, respectively, in addition to the main ration. It has been found as a result of research that the introduction of sapropel into the ration of cows has a positive effect on the digestibility of nutrients. The digestibility coefficients were higher in the animals of the 1st and 2nd experimental groups compared with the cows of the control group. Cows from the experimental groups digested all the organic substances of the ration better. During the experiment period cows of the 1st and 2nd experimental groups in contrast to the control group had higher milk yield by 11,31 and 10,38 %, respectively, milk protein yield by 10,56 and 5,95 %, milk fat yield by 17,18 and 12,99 %. It has been established that the introduction of sapropel into the ration of cows has the positive effect on the digestibility of nutrients, contributes to the increase of milk productivity, normalizes the metabolism in the body.


2021 ◽  
pp. 56-71
Author(s):  
N. Polischuk ◽  
◽  
B. Коvаlеnkо ◽  
V. Коvаlеnkо ◽  
◽  
...  

Purpose. To prepare a justification for the use of sodium and potassium salts of humic and fulvic acids (humates) as substances with biologically active properties in fish feeds based on the analysis of sources of scientific and technical information and own experimental materials, Findings. A complex general characteristic of humic substances was provided, the mechanism of biologically active action of humates on living organisms was described. Examples of the use of humates in crop production, medicine, animal husbandry and aquaculture were given. The results of our own studies on the use of humates as a feed additive for valuable objects of aquaculture were presented. Prospects for the inclusion of micro-additives of sodium and potassium humates in the composition of fish feed in order to increase fish survival and digestibility of feed were outlined. Originality. To date, the introduction of humates into fish feed as micronutrients was experimental. The analysis of scientific sources and materials of own studies gave the basis for the conclusion about the need of complex detailed studying of mechanisms of effects of humates on fish. In particular, it is of interest to study the protective properties of humates from the accumulation of heavy metals in the body of fish for the use of micronutrients of these substances in fish feeds. Practical value. The use of humate feed additives in aquaculture will help to solve such urgent problems as the prevention of excessive losses of biological material of cultivated objects, reduction of feed costs, improvement of consumer characteristics of food products. Humates, as substances of natural origin with protective and immunomodulatory action, can become substitutes for some synthetic therapeutic and prophylactic drugs. Key words: aquaculture, humates, compound feed, feed additive, growth rate, survival, feed assimilation.


2021 ◽  
Vol 32 ◽  
pp. 04002
Author(s):  
Alexey Yevglevsky ◽  
Andrey Gostev

One of the global, vital problems of humanity is iodine deficiency. According to the World Health Organization (WHO), more than 2 billion people live in conditions of iodine deficiency. people: among them, 740 million have endemic goiter, 43 million have mental retardation, more than 6 million. they suffer from cretinism (an extreme degree of mental retardation). Currently, iodine deficiency diseases are the most common non-infectious diseases in the world. What about mammalian animals? In animals, iodine performs the same functions as in humans. Animals, especially agricultural animals, are just as sensitive to iodine deficiency as humans. With a lack of iodine in the body of animals, the biosynthesis of thyroid hormones is disrupted, which leads to a decrease in the intensity of redox processes, as a result of which all types of metabolism are disrupted:-protein, fat, carbohydrate, macro – and microelement, energy. In this regard, the failure of the thyroid gland is accompanied by the development of severe pathobiochemical processes, which, in the end, leads to the clinical manifestation of pathophysiological conditions. Taking into account the fact that in conditions of constant iodine deficiency it is very problematic to ensure the health of productive animals, the issues of prevention of iodine deficiency conditions are economically significant for industrial animal husbandry. It is no accident that in countries experiencing natural iodine deficiency, state programs have been developed that provide for the use of iodine-containing additives in the diets of productive animals. Despite the fact that the simplest and most affordable method of eliminating iodine deficiency in humans and animals is the inclusion of iodized salt in the diet, however, this method can not be used for veterinary purposes. First of all, the feed method of using biologically active additives eliminates the possibility of dosed therapeutic or preventive treatment. On the pages of this article, we draw attention to the emerging prospects for the use of a new iodine-metabolic composition in non-infectious and infectious pathology, based on an iodine polymer complex known in pharmacology as iodinol and succinic acid.


2019 ◽  
Vol 16 (33) ◽  
pp. 130-139
Author(s):  
K. MAKANGALI ◽  
D. KONYSBAEVA ◽  
G. ZHAKUPOVA ◽  
V. GORBULYA ◽  
Zh. SUYUNDIKOVA

Consumer properties of meat largely depend on the physical and chemical composition. The value of camel meat is determined by its high content of nutrients in an easily digestible form necessary for the normal functioning of the body. However, the main obstacle to the use of camel meat in the production of sausage products is meat hardness and weak moisture-binding capacity of camel meat. Thus, research in this area is relevant. This article represents the study of sea buckthorn seed powder effect on the quality indicators of cooked-smoked meat products from camel meat and beef. In this regard, the chemical composition of the sea buckthorn seed powder was studied, which showed a high content of proteins and polysaccharides. It was found that the powder from the sea buckthorn seeds is a source of such biologically active substances as tocopherol 62.15 ± 2.13 mg/100 g, carotenoids 4.21 ± 0.22 mg/100 g, and flavonoids 1.54 ± 0.06%.06%. The choice of powder from the sea buckthorn seeds as part of cooked-smoked meat product from camel meat and beef is justified. It has been scientifically proven that the powder from the sea buckthorn seeds boosts the functional and technological parameters, improves the structural, mechanical and color characteristics of the finished product. In particular, it increases the product yield by 6.8%, the moisture content by 9.35%, the moisture-binding capacity by 2%, the fat-holding capacity by 3.5%; the shearing force was 5.8 N/m. As a result of the study, the use of sea buckthorn seed powder in the production of meat products from camel meat and beef has been proposed.


2021 ◽  
Vol 2 (44) ◽  
pp. 18-18
Author(s):  
Alexander Saakian ◽  
◽  

Biological feed additive "Vitacell" belongs to the group of biologically active metabolites containing live vegetative cells and spores of microorganisms of cellulolytic, probiotic and prebiotic action. The inclusion of the probiotic "Vitacella" in the diet of young cattle contributes to the stimulation of metabolic processes in the body, increasing feed conversion and improving clinical and biochemical blood parameters. The effectiveness of the use of such feed additives has been clinically proven by domestic and foreign authors. The use of these drugs helps to normalize the intestinal microflora, maintain mineral homeostasis and, as a result, increase the immune reactivity of the body, which is an integral part of the successful management of animal husbandry in the modern conditions of the food market. Keywords: PROBIOTIC, VITACELL, SYMBIOTIC MICROFLORA, BIOCHEMICAL STATUS


2020 ◽  
Vol 215 ◽  
pp. 02002
Author(s):  
Vladimir Pashtetsky ◽  
Pavel Ostapchuk ◽  
Tatiana Kuevda ◽  
Denis Zubochenko ◽  
Sergey Yemelianov ◽  
...  

Scientists working in the field of animal nutrition have recently begun to pay more attention to biologically active substances contained in plants-phytobiotics. Their complex study (composition, effect on the body) is carried out only in the last 20-30 years. It was found that the use of plant components in animal husbandry (plant parts, essential oils, extracts) was accompanied by an increase in feed conversion, an overall improvement in production indicators, and an immunostimulatory effect.


Author(s):  
В.В. КОНДРАТЕНКО ◽  
Н.Е. ПОСОКИНА ◽  
А.И. ЗАХАРОВА ◽  
М.В. ТРИШКАНЕВА

Польза для здоровья от ферментированных функциональных продуктов выражается непосредственно, через взаимодействие живых микроорганизмов, поступивших в организм вместе с пищевыми продуктами или с биологически активными добавками (пробиотический эффект), или косвенно, в результате потребления микробных метаболитов, синтезируемых в процессе ферментирования (биогенный эффект). Целый ряд исследований посвящен потенциалу процесса ферментирования для создания экономически эффективного производства пищевых продуктов с новыми функциональными и потребительскими свойствами. Присутствие в составе субстрата достаточного количества нутриентов (преимущественно сахаров) играет решающую роль в развитии молочнокислых микроорганизмов в процессе ферментирования. В этой связи были исследованы динамики концентрации глюкозы и фруктозы в результате направленной углеводной корректировки субстрата, приготовленного из белокочанной капусты сорта Парус. Установлено, что оптимальным, с точки зрения деструкции сахаров, является консорциум молочнокислых микроорганизмов видов L. casei и L. plantarum. Экспериментально установлено, что только этот консорциум удовлетворяет условие устойчивого синергизма между входящими в него видами микроорганизмов во время основного этапа ферментирования при условии углеводной корректировки сырья. Процесс углеводной корректировки целесообразно использовать при разработке технологии направленной ферментации овощного сырья. The health benefits of fermented functional products are expressed directly, through the interaction of living microorganisms that have entered the body together with food or biologically active additives (probiotic effect), or indirectly, as a result of consumption of microbial metabolites synthesized during fermentation (biogenic effect). A number of studies are devoted to the potential of the fermentation process to create cost-effective food production with new functional and consumer properties. The presence of a sufficient amount of nutrients (mainly sugars) in the substrate plays a crucial role in the development of lactic acid microorganisms during fermentation. In this regard, the dynamics of glucose and fructose concentrations were investigated as a result of directed carbohydrate adjustment of the substrate prepared from white cabbage of the Parus variety. It has been established that the consortium of lactic acid microorganisms of the species L. casei and L. plantarum is optimal from the point of view of the destruction of sugars. It has been experimentally established that only this consortium satisfies the condition of stable synergy between the species of microorganisms included in it during the main stage of fermentation, subject to carbohydrate adjustment of raw materials. It is advisable to use the process of carbohydrate correction in the development of technology for directed fermentation of vegetable raw materials.


2020 ◽  
pp. 223-228
Author(s):  
Ol'ga Valer'yevna Trineeva ◽  
Margarita Aleksandrovna Rudaya ◽  
Aleksey Ivanovich Slivkin

Sea buckthorn (Hippophae rhamnoides L.) is an object of general interest due to the high content of biologically active substances (BAS). Fruits contain water- and fat-soluble vitamins, organic acids, sugars, tannins, amino acids, flavonoids and carotenoids. The latter, in turn, give the fruits a typical yellow-orange color. Carotenoids (α-, β-, and γ-carotenes) make up 11% of the unsaponifiable fraction of sea buckthorn oil and are very valuable compounds for the cosmetics industry. Leading scientists of the world have found that carotenoids have antioxidant, antimutagenic and antitumor properties, and therefore are actively used for the prevention of cancer. The fruits of sea buckthorn are the raw materials for the pharmacopeia drug - sea buckthorn oil and a large number of various herbal medicines based on it. To separate and identify complex compounds, such as carotenoids, considerable attention is paid to the TLC method. In connection with the foregoing objective of the study was the study of the TLC profile of carotenoids of sea buckthorn fruits of various varieties. Optimal chromatographic conditions were selected that ensure the best separation of carotenoid zones in a thin sorbent layer. In the used eluting system, satisfactory separation of the chromatographic zones of carotenoids is observed, since the value of sorption selectivity is greater than unity. To characterize the chromatographic profile of each variety, it is proposed to use a value of Rs that is more independent of the influence of various parameters and does not require standards. The difference in the obtained TLC profile of carotenoids of sea buckthorn fruits of representatives of ten different varieties, as well as for the fruits of a wild plant, was established. The maximum number of chromatographic zones is observed for the Ryabinovaya variety, and the minimum for the Stolichnaya variety. It was established that by the method of «fingerprints» it is possible to identify the sort of fruits of sea buckthorn by the type of chromatographic profile of carotenoids.


Pharmacia ◽  
2021 ◽  
Vol 68 (4) ◽  
pp. 731-739
Author(s):  
Ani Slavik Dadayan ◽  
Lala Ashot Stepanyan ◽  
Tatevik Hovhannes Sargsyan ◽  
Anahit Mkhitar Hovhannisyan ◽  
Slavik Arshak Dadayan

Biologically active substances, the antioxidant and antimicrobial activity of aqueous, 70% ethylate and ethyl acetate extracts of fruits of maclura orange (Osage Orange), a representative of the Moraceae genus growing in the Ararat region of Armenia have been studied. It is found that plant extracts are rich in a wide range of pharmacologically active substances, in particular, tannins, flavonoids, organic acids, vitamins, anthocyanins, micro- and microelements, etc. Based on the investigations performed, extracts of maclura orange can be recommended as a source of biologically active substances (BAS), as well as a preventive and corrective agent in deficiency or imbalance of macro- and microelements in tissue and cellular structures in various pathological processes in the body. An ethanol extract of maclura fruits exhibits the antimicrobial activity against Bacillus subtilis 1820, E. Coli 5002, Serratia marcescens 5251 and Staphylococcus aureus ATCC-6538 strains. Maclura extracts can be used as an environmentally friendly source of antioxidants against early aging.


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