Mucosal wave measurements in the diagnosis of functional dysphonia

2019 ◽  
Vol 73 (6) ◽  
pp. 1-7 ◽  
Author(s):  
Agata Szkiełkowska ◽  
Paulina Krasnodębska ◽  
Beata Miaśkiewicz ◽  
Elżbieta Włodarczyk ◽  
Anna Domeracka-Kolodziej ◽  
...  

ntroduction: The publication describes the characteristics of the glottis in FDs objectified by OQ, measured with VSK and EGG. Aim: The aim of the study was to objectify glottal function in different types of FDs. The scope was to use open quotients gained from various mucosal wave imaging techniques for differential diagnosis of FDs. Material and Method: The study included 204 individuals. In the study, each patient underwent otolaryngological and phoniatric examination. LVS, EGG and VSK were conducted, their results were recorded and stored using an EndoSTROB-DX- -Xion GmbH (Berlin) device with DIVAS software. Results: All patients with FDs had abnormalities in LVS. A statistical analysis showed differences in LVS characteristics according to the type of FD. The mean value of OQVSK was 0.521 in the control group and 0.565 in the study group (P < 0.05). Significant differences were found between patients with hypofunctional – 0.584 and hyperfunctional dysphonia – 0.55. The QOQEGG mean value in patients with FDs was 0.581 and in the control group 0.549 (P < 0.01). There were statistically significant differences between groups of patients with hyper- and hypofunctional dysphonias. Medians amounted to 0.574 and 0.604, respectively. Authors observed different relations of OQ with the type of FD. They decided to introduce a new parameter, illustrating the proportion of QOQEGG/OQVSK. Conclusions: Videostrobokymographic and electroglottographic open quotients differentiate euphony from dysphony. The value of OQVSK and QOQEGG and their proportion varies depending on different types of functional dysphonias. The OQVSK and QOQEGG should be included in the diagnostic algorithm of voice.

Author(s):  
Mohammed Abdul Rahman ◽  
Raghunatha Rao D ◽  
Vasantha L

The present study is aimed to study and analyze the true and pseudo Cholinesterase levels in the subjects exposed to pesticides during short term by intentional or accidental intake and long term exposure due to their occupation were studied at Department of Biochemistry, SVS medical college and hospital mahbubnagar district. Whole blood cholinesterase levels and Pseudo cholinesterase levels were estimated. 150 people were taken as controls who had no medical illness and a total number of 300 cases of pesticide poisoning were selected, aged between 20 to 55 years, which consist of 150 acute poisoning and 150 chronic poisoning subjects in Mahbubnagar district, were taken as case study, the detailed case history and the type of organophosphorus pesticide taken were recorded. Mean and standard deviation (S.D) of all variables were calculated and compared with those of controls. Statistical significance was assessed and P-value <0.05 were considered significant.           During acute poisoning the mean value of Whole blood cholinesterase/True cholinesterase (U / L) in acute poisoning cases on first day was 1.267± 0.612 on 3th day was 1.651±0.647, on 7th day was 2.221±0.684 and at the end of 6 months was 3.970±0.404.The difference between the study group and control group (4.0 ± 0.39) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in acute poisoning cases on first day was 2213.05 ± 1749.81, on 3th day was 2862.3 ± 2025.6, on 7th day was 4008.4 ± 2355.9 and at the end of 6 months was 7708.34 ± 880.72.The difference between the study group and control group (7991.97 ± 1276.5) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. During chronic poisoning (exposure) the mean value of Whole blood cholinesterase (U/L) in controls is 4.0 ± 0.39 as compared to 3.019 ± 0.848 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in controls was 7991.97 ± 1276.5 as compared to 6214 ± 1189 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant.


2019 ◽  
Vol 47 (7) ◽  
pp. 704-709
Author(s):  
Mosunmola A. Adeku ◽  
Omololu Adegbola ◽  
Godwin O. Ajayi

Abstract Background Spontaneous miscarriages are common pregnancy complications which result in psychological and emotional burden in the affected women. It is therefore necessary to identify biomarkers that can predict pregnancy outcome in women with threatened miscarriages so as to assist in their counselling and management. Methods The study compared levels of maternal serum CA125 in 65 pregnancies with threatened miscarriages (study group) with 65 normal intrauterine pregnancies (control group) between 6 weeks and 19 weeks + 6 days gestation using an enzyme linked immunosorbent assay (ELISA) technique. Results The mean age of the study and control groups were 29.5 ± 0.14 years and 30.1 ± 0.14 years, respectively. The mean serum CA125 in the study group was 30.1 ± 1.1 IU/mL while that of the control group was 22.9 ± 1.2 IU/mL and this was statistically significant (P = 0.0001). The mean serum CA125 level in the women whose pregnancies were aborted (aborters) was 34.8 ± 1.4 IU/mL while the mean value among those whose pregnancies continued till term (non-aborters) was 27.3 ± 1.2 IU/mL. This was statistically significant (P = 0.001). Further analysis using CA125 ≥36.2 IU/mL (mean value of serum CA125 among aborters + 1 standard deviation) as a threshold for intrauterine pregnancies that eventually got aborted showed a sensitivity of 66.7%, specificity of 83.3%, positive predictive value of 55.6%, negative predictive value of 88.9% and the diagnostic effectiveness (accuracy) was 79.4%. Conclusion The measurement of serum CA125 is a useful predictor of pregnancy outcome in threatened miscarriages.


2020 ◽  
Vol 77 (8) ◽  
pp. 852-858
Author(s):  
Vladan Djordjevic ◽  
Mila Jovanovic ◽  
Sanja Colic ◽  
Milena Stasevic ◽  
Amina Asotic ◽  
...  

Background/Aim. According to the World Health Organization (WHO), there is an increasing prevalence of mental disorders among children and adolescents worldwide. Previous studies have shown that people with mental disorders, regardless age, have an increased prevalence of dental caries due to several reasons. The aim of this study was to determine prevalence of dental caries in adolescents with mental disorders and to consider possible risk factors that might contribute to their current dental health status. Methods. The study was conducted as an observational cross-sectional study. The study group comprised 70 randomly selected hospitalized adolescents with mental disorders. The control group comprised 70 randomly chosen mentally healthy adolescents. They were matched to the study group by gender and age. All the participants were subjected to targeted dental examination according to criteria recommended by the WHO. Collection of data related to mental disorders of the study group was obtained from the patient?s medical records. All collected data were organized and analyzed by descriptive statistical parameters and regression models. Results. Majority of the study group patients were diagnosed with schizophrenia, schizotypal and delusional disorders (F20-F29), as well as behavioral and emotional disorders usually occurring in childhood and adolescence (F90-F98). Almost 90% of them were treated with antipsychotics of the second generation, as monotherapy or in combination with first-generation antipsychotics. Adolescents with mental disorders had significantly more carious and extracted teeth and three times less filled teeth than mentally healthy adolescents in the control group. The mean value of the decay-missing-filled teeth (DMF) index in the study group patients was also significantly higher than the mean value of DMF index in the control group subjects. Conclusion. It seems that mental disorder among adolescents mainly affects oral health indirectly, decreasing motivation of patients in maintaining oral hygiene.


Author(s):  
Sameer Jagrwal ◽  
Gourav Kumar Goyal ◽  
SK Tak

Background: Hypertensive disorders of pregnancy complicate about 8% of all gestations. Hypertensive disorders are responsible for significant maternal and perinatal morbidity and mortality. AIMS: To determine the hematological parameters and morbidity in neonates born to mothers with gestational hypertension, pre-eclampsia or eclampsia syndrome and in neonates born to normotensive mothers without any maternal complications or medical illness with special reference to platelet count and neutrophil count. Methods and Material: The study was a prospective study conducted on neonates born to pregnant women complicated with gestational hypertension, pre-eclampsia or eclampsia syndrome and neonates born to normotensive mothers recruited at Neonatal Intensive Care Unit and Post natal wards who were delivered at Ananta Hospital and AIMS & RC, Rajsamand (Raj.) from October 2018 to September 2019 and the hematological parameters of these babies were studied. Results: In our study we observed that the mean value of platelet count were significantly lower in study group compared to control group which was highly Statistical significant (p<0.001). The mean value of PT, aPTT, Bleeding Time and Clotting time were significantly higher in study group, as compared to control group. The statistical analytic differences were highly significant in all parameters i.e. PT, aPTT, Bleeding Time and Clotting time (P<0.001). Conclusion: To conclude early hematological screening of babies are recommended to facilitate early detection and management of serious neonatal complications describes above, to decrease morbidity and improved growth, development and survival. Keywords:  Pre-eclampsia, Eclampsia, Gestational Hypertension, Newborns.


Author(s):  
Divya Raj ◽  
Subramaniam Santhi ◽  
G. J. Sara Sapharina

AbstractObjectivesThis study finds out the effectiveness of neurobic exercise program on memory and depression among elderly residing in old age homes.MethodsThe non-probability purposive sampling technique was used for sample selection. Wechsler's memory scale (WMS-IV) and Geriatric depression scale (GDS) were the instruments used to assess the memory and depression among elderly during the pretest and posttest, respectively and the researcher had developed data sheet to collect information about the background variables using interview technique.ResultsThe neurobic exercise program was found to be effective in reducing depression among elderly residing in old age homes. There was a significant difference (p<0.001) in the level of depression had been found during the pretest and posttest in the interventional group. There was a statistically significant difference (p<0.001) found between the study group and in the control group. There was significant correlation (r=0.417, p<0.05) found between the memory and depression during the pretest in the study group among the elderly. A statistically significant association (p<0.05) found in the mean scores of depression and marital status of the elderly during the pretest in the study group and there was a significant association (p<0.01) found in the mean scores of depression and the gender of the elderly during the pretest and posttest in the non interventional group were found.ConclusionsThe findings suggested that neurobic exercise program is an effective intervention in improving memory and reducing depression.


Biology ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 358
Author(s):  
Javier Aragoneses ◽  
Ana Suárez ◽  
Nansi López-Valverde ◽  
Francisco Martínez-Martínez ◽  
Juan Manuel Aragoneses

The aim of this study was to evaluate the effect of implant surface treatment with carboxyethylphosphonic acid and fibroblast growth factor 2 on the bone–implant interface during the osseointegration period in vivo using an animal model. The present research was carried out in six minipigs, in whose left tibia implants were inserted as follows: eight implants with a standard surface treatment, for the control group, and eight implants with a surface treatment of carboxyethylphosphonic acid and immobilization of FGF-2, for the test group. At 4 weeks after the insertion of the implants, the animals were sacrificed for the histomorphometric analysis of the samples. The means of the results for the implant–bone contact variable (BIC) were 46.39 ± 17.49% for the test group and 34.00 ± 9.92% for the control group; the difference was not statistically significant. For the corrected implant–bone contact variable (BICc), the mean value of the test group was 60.48 ± 18.11%, and that for the control group, 43.08 ± 10.77%; the difference was statistically significant (p-value = 0.035). The new bone formation (BV/TV) showed average results of 27.28 ± 3.88% for the test group and 26.63 ± 7.90% for the control group, meaning that the differences were not statistically significant (p-value = 0.839). Regarding the bone density at the interthread level (BAI/TA), the mean value of the test group was 32.27 ± 6.70%, and that of the control group was 32.91 ± 7.76%, with a p-value of 0.863, while for the peri-implant density (BAP/TA), the mean value of the test group was 44.96 ± 7.55%, and that for the control group was 44.80 ± 8.68%, without a significant difference between the groups. The current research only found a significant difference for the bone–implant contact at the cortical level; therefore, it could be considered that FGF-2 acts on the mineralization of bone tissue. The application of carboxyethylphosphonic acid on the surface of implants can be considered a promising alternative as a biomimetic coating for the immobilization of FGF-2. Despite no differences in the new bone formation around the implants or in the interthread or peri-implant bone density being detected, the biofunctionalization of the implant surface with FGF-2 accelerates the mineralization of the bone–implant interface at the cortical level, thereby reducing the osseointegration period.


1984 ◽  
Vol 98 (12) ◽  
pp. 1213-1216 ◽  
Author(s):  
Harbans Lal ◽  
O. P. Sachdeva ◽  
H. R. Mehta

AbstractSerum immunoglobulin (IgG, IgA and IgM) levels were determined in patients with chronic tonsillitis before and one month after tonsillectomy. The preoperative levels of serum IgG, IgA and IgM were significantly higher when compared with the controls. The increase may be due to repeated antigenic stimulation. The post-operative levels for the three immunoglobulins were decreased; however, a significant reduction was observed for IgG only where the mean value was comparable with the control group. The data confirm that tonsillectomy does not disturb the humoral immune system of the body.


The purpose of the research was to investigatethe effect of activity-based games on the academic achievement of graduate-level pupils in social sciences.An experimental research design with a pre-and post-test control group was used in this study. As pre-test and post-test, MCQ achievement tests containing 70 items were used as research methods for data collecting. The initial stage in this initiative was to collect data on what inspires children to learn. Both groups took a pre-test, and the results were tallied.The project's second phase was to study the effects of variousactivities on academic achievement. Both groups were given an MCQ performance test. The T-test was used to analyze the data. The findings of this study demonstrated that, compared to the control group, mostpupils'marks improved in the experimental group. The mean value showedthat experimental group participants scored 18.77on the post-test, while control group students scored 16.21. According to a post-lesson poll, most students regarded activity-based games to be more engaging than lecture-based instruction.


Author(s):  
Kazuhiro Tochigi ◽  
Ryo Nagaoka ◽  
Jens Erik Wilhjelm ◽  
Hideyuki Hasegawa

Abstract In the early stage of atherosclerosis, the luminal surface of the arterial wall becomes rough. Methods for distinguishing between the reflected and backscattered components in the ultrasonic echo from the arterial wall has the potential to be used as a method for assessment of the roughness of the arterial wall. In this study, we proposed a method to distinguish between the reflected and backscattered components using a technique based on plane wave compounding. This method was evaluated by experiments using planar phantoms with rough surfaces made of polyurethane rubber. The coefficient of variation calculated from the mean value of the reflection component and the standard deviation of the backscattering component was proportional to the roughness of the rubber phantom. This result shows the potential usefulness of this method for analyzing surface roughness of the arterial wall.


2017 ◽  
Vol 1 ◽  
pp. 54
Author(s):  
Arita Destianingsih ◽  
Ari Satria

The aim of this study was to know the effectiveness of the use of alphabet cards game as interesting tool to explain vocabularies and it make it easier to remember their meanings. This study belongs to the quasi experimental research and presents pre-test, post test and to investigate the effect of using alphabet cards game on vocabulary mastery of commercial business administration students. The participants were the students from commercial business administration students at the third semester (N=54) of State Polytechnic Bengkalis and divided into two groups. Both groups were taught vocabulary, however, the experimental group students who are exposed to alphabet cards game and the controlled group students who received conventional method. Pre-test and post-test were given to both experimental group students and controlled group students. The score of the vocabulary tests were compared through independent sample t-test. The mean value of pre-test of experimental class was 61.35, while the control class was 52.23. After learning using alphabet card games in experimental class the mean value obtained in post-test was 78.85, while in control class was 59.04.  The improved of learning outcomes can be seen from the level of significance was 0.000 and it was lower than t test 0.000<0.05.  It means that the hypothesis null is not accepted. Therefore, it can be concluded that the score of the students in learning vocabulary between the experimental group and control group was significantly different. The experimental group students who learned vocabulary using alphabet cards game had increased their vocabulary mastery.


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